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1
المؤلفون: Nicole Trainor, E V Lis, Anthony G. DiLella, Terrence P. McDonald, Annie Liang, Mark E. Layton, Duane R. Reiss, Michael J. Kelly, Sanderson Philip E, James Yergey, Kevin J. Rodzinak, Steven D. Young, Guy R. Seabrook, Christine Fandozzi, Michael E. Cunningham, Scott D. Mosser, Mark O. Urban, John F. Fay, Hao Wang, Kenneth S. Koblan, Rodney A. Bednar
المصدر: ACS Chemical Neuroscience. 2:352-362
مصطلحات موضوعية: Male, ERG1 Potassium Channel, Physiology, Cognitive Neuroscience, Administration, Oral, Biological Availability, Cyclopentanes, Catalepsy, Pharmacology, Receptors, N-Methyl-D-Aspartate, Biochemistry, Rotarod performance test, Rats, Sprague-Dawley, Dogs, Isomerism, Piperidines, Oral administration, Drug Discovery, medicine, Animals, Benzopyrans, Receptor, Ligation, Oxadiazoles, Chemistry, Antagonist, Parkinson Disease, Cell Biology, General Medicine, medicine.disease, Macaca mulatta, Ether-A-Go-Go Potassium Channels, Rats, Pyrimidines, Spinal Nerves, nervous system, Neuropathic pain, Excitatory Amino Acid Antagonists, Neuralgia, NMDA receptor, Female, Indicators and Reagents, Half-Life
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2
المؤلفون: Gene G. Kinney, Anthony G. DiLella, P. Jeffrey Conn, Ornella Valenti, David L. Williams, J. Fred Hess, Terrence P. McDonald, Michael J. Marino, Michelle K. Clements, Ruiping Wang, Julie A. O'Brien
المصدر: Proceedings of the National Academy of Sciences. 100:13668-13673
مصطلحات موضوعية: Male, Agonist, Time Factors, Parkinson's disease, medicine.drug_class, Dopamine, Allosteric regulation, Biology, Pharmacology, Receptors, Metabotropic Glutamate, Models, Biological, Cell Line, Rats, Sprague-Dawley, chemistry.chemical_compound, AMN082, medicine, Animals, Humans, Benzopyrans, Multidisciplinary, Metabotropic glutamate receptor 4, Brain, Esters, Parkinson Disease, Long-term potentiation, Biological Sciences, Potentiator, medicine.disease, Rats, Electrophysiology, Models, Chemical, chemistry, Chromones, Synapses, Allosteric Site, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c7dee85a6ed566f21bd820ae87d5c2b
https://doi.org/10.1073/pnas.1835724100 -
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المؤلفون: Michael J. Marino, P. Jeffrey Conn, Gene G. Kinney, Ornella Valenti, E V Lis, Marion Wittmann, Anthony G. DiLella
المصدر: The Journal of Neuroscience. 23:7218-7226
مصطلحات موضوعية: Male, Reserpine, Striatum, In Vitro Techniques, Motor Activity, Biology, Globus Pallidus, Receptors, Metabotropic Glutamate, Inhibitory postsynaptic potential, Indirect pathway of movement, Synaptic Transmission, Rats, Sprague-Dawley, Synapse, Mice, Basal ganglia, Excitatory Amino Acid Agonists, Animals, gamma-Aminobutyric Acid, Mice, Knockout, Adrenergic Uptake Inhibitors, Aminobutyrates, General Neuroscience, Neural Inhibition, Parkinson Disease, Corpus Striatum, Electric Stimulation, Rats, Disease Models, Animal, Subthalamic nucleus, Globus pallidus, nervous system, Metabotropic glutamate receptor, Synapses, Neuroscience, Cellular/Molecular
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cf52171699aea8a09ce232cc27823a33
https://doi.org/10.1523/jneurosci.23-18-07218.2003 -
4
المؤلفون: Christopher P. Austin, Doreen E. Cashen, Sheng-Shung Pong, Brian D. Spar, Brett Connolly, Tung Ming Fong, D. Euan MacIntyre, Carina P. Tan, Michael R. Tota, Ravi P. Nargund, R. S. L. Chang, Oksana C. Palyha, Constantin Tamvakopoulos, Deborah L. Drazen, Anthony G. DiLella, Jennifer E. Drisko, David J. Figueroa, Tanya MacNeil, Andreas W. Sailer, David H. Weinberg, Randy J. Nelson, Charles Rosenblum, Cathy R.-R.C. Huang, Rui Tang, Arthur A. Patchett, Xiao-Ming Guan, Hong Yu, George J. Christ, Andrew D. Howard, Lex H.T. Van der Ploeg, William J. Martin, Aurawan Vongs, Iyassu K. Sebhat, Ralph A. Stearns
المصدر: Proceedings of the National Academy of Sciences. 99:11381-11386
مصطلحات موضوعية: Male, Agonist, medicine.medical_specialty, DNA, Complementary, Intracranial Pressure, medicine.drug_class, Blood Pressure, In Vitro Techniques, Biology, Somatosensory system, Mice, Sexual Behavior, Animal, Nerve Fibers, Internal medicine, Copulation, medicine, Animals, Glans, In Situ Hybridization, DNA Primers, Multidisciplinary, Reverse Transcriptase Polymerase Chain Reaction, Human penis, Feeding Behavior, Ribonuclease, Pancreatic, Biological Sciences, Spinal cord, Electric Stimulation, Mice, Inbred C57BL, Melanocortin 4 receptor, medicine.anatomical_structure, Endocrinology, Receptors, Corticotropin, Models, Animal, Receptor, Melanocortin, Type 4, Brainstem, Energy Metabolism, Penis
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::341db11f0e12a0307d07e04176cd4aad
https://doi.org/10.1073/pnas.172378699 -
5
المؤلفون: Brian Hellmig, Susan S. Hoog, Daniel J. O'Shannessy, Kevin O'Donnell, Cheryl A. Janson, Christine Debouck, Ward W. Smith, Michael S. McQueney, Anthony G. DiLella, Xiayang Qiu, Sherin S. Abdel-Meguid
المصدر: Biochemistry. 36:14023-14029
مصطلحات موضوعية: Models, Molecular, Proteases, Protein Conformation, Herpesvirus 2, Human, viruses, medicine.medical_treatment, Molecular Sequence Data, Herpesvirus 1, Human, Crystallography, X-Ray, medicine.disease_cause, Biochemistry, Viral Proteins, Capsid, Organophosphorus Compounds, medicine, Protease Inhibitors, Serine protease, Binding Sites, Protease, biology, Protease inhibitor complex, Chemistry, Serine Endopeptidases, Subtilisin, medicine.disease, Virology, Recombinant Proteins, NS2-3 protease, Cold sore, Herpes simplex virus, biology.protein
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6
المؤلفون: Anthony G. DiLella, Richard L. Jarvest, Daniel J. O'Shannessy, Andrew West, Christine Debouck, Arunbai Patel, Ivan Leo Pinto, Kevin O'Donnell, Joselina G. Gorniak
المصدر: Bioorganic & Medicinal Chemistry Letters. 6:2467-2472
مصطلحات موضوعية: Proteases, Stereochemistry, Chemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Mechanism based, Biochemistry, Combinatorial chemistry, Serine, Covalent bond, Drug Discovery, Molecular Medicine, Molecular Biology
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المؤلفون: Sherin S. Abdel-Meguid, Brian D. Hellmig, Jeffrey S. Culp, Ward W. Smith, Xiayang Qiu, Anthony G. DiLella, Cheryl A. Janson, Susan S. Hoog
المصدر: Nature. 383:275-279
مصطلحات موضوعية: Models, Molecular, Human cytomegalovirus, Protein Folding, Protein Conformation, viruses, medicine.medical_treatment, Molecular Sequence Data, Cytomegalovirus, Biology, Crystallography, X-Ray, medicine.disease_cause, Catalysis, Virus, Herpesviridae, Endopeptidases, Catalytic triad, medicine, Humans, Amino Acid Sequence, Serine protease, Binding Sites, Multidisciplinary, Protease, Serine Endopeptidases, virus diseases, medicine.disease, Virology, NS2-3 protease, Mutagenesis, biology.protein
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المؤلفون: Ian J. Reynolds, Sonia Poli, Lisa M. Hodge, Julien Bortoli, Anthony G. DiLella, Abdhelak Bessif, Brice Campo, Christelle Bolea, Amy Jo Koser, Francoise Girard, Delphine Charvin, Fred Hess, Bin Luo, Emmanuel Le Poul, Susan E. Browne, Karen M. Smith, Nigel J. Liverton
المصدر: The Journal of pharmacology and experimental therapeutics. 343(1)
مصطلحات موضوعية: Male, Allosteric modulator, Parkinson's disease, Allosteric regulation, Mice, Transgenic, Catalepsy, Pharmacology, Receptors, Metabotropic Glutamate, Rats, Sprague-Dawley, Mice, Quinpirole, Allosteric Regulation, medicine, Excitatory Amino Acid Agonists, Animals, Humans, Receptor, Chemistry, Metabotropic glutamate receptor 4, Parkinson Disease, medicine.disease, Rats, Mice, Inbred C57BL, Disease Models, Animal, medicine.anatomical_structure, HEK293 Cells, Molecular Medicine, Forelimb, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8deb76b619f9a1ec3f0c438cca31fb52
https://pubmed.ncbi.nlm.nih.gov/22787118 -
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المؤلفون: Barbara E. Bierer, Robert J. Craig, Wei Zhang, Anthony G. DiLella, Jin Yong-Jiu, Barbara A. Hendrickson, Steven J. Burakoff
المصدر: Gene. 134:271-275
مصطلحات موضوعية: TBX1, Molecular Sequence Data, Biology, Tacrolimus, Homology (biology), Tacrolimus Binding Proteins, Mice, Genetics, Animals, Humans, Genomic library, Amino Acid Sequence, Cloning, Molecular, Gene, Heat-Shock Proteins, Sequence Homology, Amino Acid, Binding protein, Intron, Nucleic acid sequence, Exons, General Medicine, Introns, Blotting, Southern, FKBP, Carrier Proteins
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10
المؤلفون: Anthony G. DiLella, Richard L. Jarvest, Christine Debouck, Andrew West, Joselina G. Gorniak, Ivan Leo Pinto, Arunbai Patel, Kevin O'Donnell, Daniel J. O'Shannessy
المصدر: ChemInform. 28
مصطلحات موضوعية: Serine, Proteases, Biochemistry, Chemistry, Covalent bond, Mechanism based, General Medicine