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1دورية أكاديمية
المؤلفون: Thomas Lanyon-Hogg, Naoko Masumoto, George Bodakh, Antonio D. Konitsiotis, Emmanuelle Thinon, Ursula R. Rodgers, Raymond J. Owens, Anthony I. Magee, Edward W. Tate
المصدر: Data in Brief, Vol 7, Iss , Pp 257-281 (2016)
مصطلحات موضوعية: Computer applications to medicine. Medical informatics, R858-859.7, Science (General), Q1-390
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: Malgorzata Broncel, Remigiusz A Serwa, Paulina Ciepla, Eberhard Krause, Margaret J. Dallman, Anthony I. Magee, Edward W. Tate
المصدر: Data in Brief, Vol 4, Iss C, Pp 379-383 (2015)
مصطلحات موضوعية: Protein modification, Myristoylation, Tagging by substrate, Modification site, Computer applications to medicine. Medical informatics, R858-859.7, Science (General), Q1-390
وصف الملف: electronic resource
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3
المؤلفون: Milon Mondal, Balazs Pogranyi, Matthew J. Fuchter, Leran Zhang, Christian Siebold, Jake L. Greenfield, Lea Sefer, Sebastian A. Andrei, Thomas Lanyon-Hogg, Markus Ritzefeld, Callum D. Johnston, Joshua Newington, Claire E. Coupland, Anthony I. Magee, Edward W. Tate
المصدر: Angewandte Chemie International Edition
Angewandte Chemie (International Ed. in English)مصطلحات موضوعية: 0301 basic medicine, Light, Pyridines, enzymes, membrane-bound O-acyltransferase, MBOAT, Photochemistry, 010402 general chemistry, 01 natural sciences, Catalysis, Homology (biology), Small Molecule Libraries, Structure-Activity Relationship, 03 medical and health sciences, HHAT, Acetyltransferases, Hedgehog acyltransferase, Humans, Binding site, photoaffinity labelling, Hedgehog, 030304 developmental biology, chemistry.chemical_classification, 0303 health sciences, Binding Sites, Palmitoyl Coenzyme A, Communication, Affinity Labels, General Chemistry, General Medicine, Small molecule, Communications, 3. Good health, 0104 chemical sciences, Kinetics, 030104 developmental biology, Enzyme, chemistry, Hedgehog signalling, Acyltransferase, Medicinal Chemistry
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المؤلفون: Claire E. Coupland, Sebastian A. Andrei, T. Bertie Ansell, Loic Carrique, Pramod Kumar, Lea Sefer, Rebekka A. Schwab, Eamon F.X. Byrne, Els Pardon, Jan Steyaert, Anthony I. Magee, Thomas Lanyon-Hogg, Mark S.P. Sansom, Edward W. Tate, Christian Siebold
المساهمون: Department of Bio-engineering Sciences, Structural Biology Brussels, Cancer Research UK, Biotechnology and Biological Sciences Research Council (BBSRC)
المصدر: Molecular Cell
مصطلحات موضوعية: Biochemistry & Molecular Biology, STRUCTURE VALIDATION, animal structures, PROTEINS, Protein Conformation, Acylation, Hedgehog acyl transferase, membrane-bound O-acyltransferase, Heme, Sonic Hedgehog signaling, Molecular Dynamics Simulation, CRYO-EM, Article, Structure-Activity Relationship, Allosteric Regulation, Catalytic Domain, Chlorocebus aethiops, Animals, Humans, Hedgehog Proteins, Enzyme Inhibitors, PALMITOYLATION, Molecular Biology, 11 Medical and Health Sciences, Science & Technology, IDENTIFICATION, REFINEMENT, Palmitoyl Coenzyme A, ALGORITHMS, Cryoelectron Microscopy, RECOGNITION, Membrane Proteins, small molecule inhibitor, drug, cryo-EM structure, Cell Biology, molecular dynamics simulations, 06 Biological Sciences, palmitoyl co enzyme A, HEK293 Cells, embryonic structures, COS Cells, VISUALIZATION, integral membrane protein, Life Sciences & Biomedicine, Acyltransferases, GENERATION, Developmental Biology, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4126d9db15243ce2d4d7d77c45ec15bc
https://pubmed.ncbi.nlm.nih.gov/34890564 -
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المؤلفون: Thomas Lanyon-Hogg, Markus Ritzefeld, Leran Zhang, Balazs Pogranyi, Milon Mondal, Lea Sefer, Callum D. Johnston, Claire E. Coupland, Sebastian A. Andrei, Joshua Newington, Anthony I. Magee, Christian Siebold, Edward W. Tate
المساهمون: Cancer Research UK, Biotechnology and Biological Sciences Research Council (BBSRC), Engineering & Physical Science Research Council (EPSRC)
مصطلحات موضوعية: Science & Technology, PROTEINS, Chemistry, Multidisciplinary, enzymes, Organic Chemistry, membrane-bound O-acyltransferase, ACYLATION, Chemistry, TARGET, Hedgehog signalling, Physical Sciences, Hedgehog acyltransferase, GHRELIN, photoaffinity labelling, 03 Chemical Sciences
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9e59cf7fba46be40356dcde9c651c2d
http://hdl.handle.net/10044/1/87627 -
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المؤلفون: Anthony I. Magee, Nattawadee Panyain, Thomas Lanyon-Hogg, Markus Ritzefeld, Nicola O’Reilly, Ganka Bineva-Todd, Jasmine K. Bickel, Edward W. Tate, Cory A Ocasio, Lea Sefer, Christian Siebold, A.F. Rudolf
المساهمون: Pancreatic Cancer Research Fund, Cancer Research UK
المصدر: Chemical Science
مصطلحات موضوعية: Chemistry, Multidisciplinary, Lipid-anchored protein, 010402 general chemistry, 01 natural sciences, Acylation, Palmitoylation, Hydrolase, medicine, Transferase, PALMITOYLATION, PROBE, Chemical Biology & High Throughput, chemistry.chemical_classification, Science & Technology, HEDGEHOG, 010405 organic chemistry, Chemistry, Drug discovery, Neurodegeneration, General Chemistry, medicine.disease, 0104 chemical sciences, Enzyme, Biochemistry, Physical Sciences, lipids (amino acids, peptides, and proteins), INHIBITORS, 03 Chemical Sciences, Structural Biology & Biophysics
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac31b40b5b5d89fececdd949daee3aed
https://doi.org/10.1039/c9sc01785b -
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المؤلفون: Emmanuelle Thinon, Ursula R. Rodgers, Antonio D. Konitsiotis, Anthony I. Magee, Naoko Masumoto, Edward W. Tate, George Bodakh, Raymond J. Owens, Thomas Lanyon-Hogg
المساهمون: Cancer Research UK
المصدر: Analytical Biochemistry
مصطلحات موضوعية: YnC15, heptadec-16-ynoic acid, Peptide, Protein lipidation, 01 natural sciences, Biochemistry, OTG, n-octyl β-d-glucopyranoside, Substrate Specificity, PATHWAY, PCR, polymerase chain reaction, SONIC-HEDGEHOG, Protein palmitoylation, TBTA, tris[(1-benzyl-1H-1,2,3-triazol-4-yl)methyl]amine, Enzyme Inhibitors, Sonic hedgehog, PROTEIN LIPIDATION, chemistry.chemical_classification, 0303 health sciences, Palmitoyl Coenzyme A, biology, Click chemistry, Chemistry, HRP, horseradish peroxidase, HTS, high-throughput screen, Hedgehog signaling pathway, MBOAT, membrane bound O-acyltransferase, Acyltransferase, Hh, hedgehog, Physical Sciences, Fatty Acids, Unsaturated, Shh, sonic hedgehog, RT, room temperature, Oligopeptides, Life Sciences & Biomedicine, 0301 Analytical Chemistry, CoA, coenzyme A, Biochemistry & Molecular Biology, SDS, sodium dodecyl sulfate, TCEP, tris(2-carboxyethyl)phosphine, Lipoylation, Recombinant Fusion Proteins, Detergents, cat–ELCCA, catalytic assay using an enzyme-linked click chemistry assay, PBS, phosphate-buffered saline, Biophysics, Enzyme-Linked Immunosorbent Assay, click–ELISA, click chemistry armed enzyme-linked immunosorbent assay, CHAPS, 3-[(3-cholamidopropyl)dimethylammonio]-1-propanesulfonate, HEK293a, human embryonic kidney 293a, Article, Biochemical Research Methods, PROBES, 03 medical and health sciences, Palmitoylation, HHAT, Hhat, hedgehog acyltransferase, 0399 Other Chemical Sciences, Hedgehog acyltransferase, Humans, Biotinylation, Hedgehog Proteins, Maltose, DDM, n-dodecyl β-d-maltopyranoside, Molecular Biology, PAGE, polyacrylamide gel electrophoresis, 030304 developmental biology, Science & Technology, 010405 organic chemistry, HUMAN-CELLS, GOAT, ghrelin-O-acyltransferase, Chemistry, Analytical, CANCER PROGRESSION, 0601 Biochemistry And Cell Biology, Cell Biology, Peptide Fragments, MBOAT, 0104 chemical sciences, HEK293 Cells, Immobilized Proteins, Solubility, biology.protein, BSA, bovine serum albumin, Streptavidin, PTM, posttranslational modification, INHIBITORS, Protein Processing, Post-Translational, Acyltransferases
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المؤلفون: Remigiusz A. Serwa, Malgorzata Broncel, Anthony I. Magee, Margaret J. Dallman, Eberhard Krause, Edward W. Tate, Paulina Ciepla
المصدر: Data in Brief, Vol 4, Iss C, Pp 379-383 (2015)
Data in Brief, 4: 379-383
Data in Briefمصطلحات موضوعية: Multidisciplinary, biology, Tagging by substrate, Modification site, Myristoylation, Protein modification, HEK 293 cells, Myristic acid, Protein lipidation, biology.organism_classification, lcsh:Computer applications to medicine. Medical informatics, Combinatorial chemistry, HeLa, chemistry.chemical_compound, chemistry, Biochemistry, Proteome, lcsh:R858-859.7, Azide, lcsh:Science (General), Zebrafish, Data Article, lcsh:Q1-390
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المصدر: Molecular Membrane Biology. 32:65-74
مصطلحات موضوعية: animal structures, Cell, Cell Biology, Biology, Hedgehog signaling pathway, Cell biology, medicine.anatomical_structure, Biochemistry, embryonic structures, Extracellular, biology.protein, medicine, Animals, Humans, Hedgehog Proteins, Protein Multimerization, Signal transduction, Sonic hedgehog, Protein Processing, Post-Translational, Molecular Biology, Intracellular, Tissue homeostasis, Signal Transduction, Morphogen
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المؤلفون: Paulina Ciepla, Martin Spitaler, Antonios D. Konitsiotis, Thomas Lanyon-Hogg, Anthony I. Magee, Edward W. Tate, Biljana Jovanovic
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: Lipoylation, Acyltransferase, Amino Acid Motifs, Biology, Topology, Biochemistry, Hedgehog Signaling Pathway, HHAT, Palmitoylation, Catalytic Domain, Membrane Biology, Humans, Protein palmitoylation, Molecular Biology, Hedgehog, Secretory pathway, Cancer, Endoplasmic reticulum, Cell Biology, MBOAT, Transmembrane protein, 3. Good health, Cell biology, Transmembrane Domain, Protein Palmitoylation, Transmembrane domain, HEK293 Cells, Mutation, Click Chemistry, Protein Processing, Post-Translational, Acyltransferases, HeLa Cells
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1117d955cb0ceba20ae541660890c90e
https://doi.org/10.1074/jbc.m114.614578