نتائج البحث - "Antigens Neoplasm/immunology"

المساهمون: Institut Cochin (IC UM3 (UMR 8104 / U1016)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Centre de Physiopathologie Toulouse Purpan (CPTP), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Instituto Oswaldo Cruz / Oswaldo Cruz Institute [Rio de Janeiro] (IOC), Fundação Oswaldo Cruz (FIOCRUZ), Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), This work was funded by Brazilian National Council for Scientific and Technological Development (CNPq), L.G.P. was supported by grant no. 140718/2019-2 and V.C.A. was supported by grant no. 310329/2019-1. The Coordination for the Improvement of Higher Education Personnel (CAPES), with support from the Program PrInt-Fiocruz-CAPES, the Oswaldo Cruz Institute (IOC), Oswaldo Cruz Foundation (Fiocruz), and Mercosur Fund for Structural Convergence (FOCEM, 03/11) provided funding for L.G.P. and V.C.A. E.D. was supported by a funding from the European Union's Horizon 2020 Research and Innovation Programme under grant agreement no. 667980., European Project: 667980,H2020,H2020-PHC-2015-two-stage,CARAT(2016), PINIER, CHRISTINE, Chimeric Antigen Receptors (CARs) for Advanced Therapies - CARAT - - H20202016-01-01 - 2019-12-31 - 667980 - VALID, Université de Toulouse (UT)-Université de Toulouse (UT)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Fundação Oswaldo Cruz / Oswaldo Cruz Foundation (FIOCRUZ)

المصدر: Journal of Leukocyte Biology
Journal of Leukocyte Biology, 2020, 108 (4), pp.1067-1079. ⟨10.1002/JLB.1MR0520-746R⟩

مصطلحات موضوعية: 0301 basic medicine, MESH: T-Lymphocytes* / pathology, medicine.medical_treatment, T-Lymphocytes, MESH: Antigens, Neoplasm / immunology, MESH: Cell Movement / immunology, Review, Immunotherapy, Adoptive, 0302 clinical medicine, Cancer immunotherapy, [SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Cell Movement, Neoplasms, Tumor Microenvironment, Immunology and Allergy, Cytotoxic T cell, chimeric antigen receptor engineering, Receptors, Chimeric Antigen, MESH: Neoplasms* / therapy, medicine.anatomical_structure, motility, MESH: Immunotherapy, Adoptive, [SDV.MHEP.MI] Life Sciences [q-bio]/Human health and pathology/Infectious diseases, Antibody, MESH: T-Lymphocytes* / immunology, T cell, extracellular matrix, Immunology, Reviews, Biology, MESH: Neoplasms* / pathology, T cell trafficking, Guest Editors: João P.B. Viola, Lis Antonelli, Martin Bonamino, Jose Alves Filho, and Helder Nakaya, 03 medical and health sciences, Antigens, Neoplasm, medicine, Humans, MESH: Receptors, Chimeric Antigen / immunology, MESH: Tumor Microenvironment / immunology, Tumor microenvironment, MESH: Humans, cancer immunotherapy, Cell Biology, Immune checkpoint, Chimeric antigen receptor, 030104 developmental biology, Cancer cell, Cancer research, biology.protein, XLIV Congress of the Brazilian Society of Immunology, MESH: Neoplasms* / immunology, 030215 immunology

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfc95014385f55a1f07ac5fb0e34df16
https://pubmed.ncbi.nlm.nih.gov/32620049

View record at Wiley

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Prérequis pour une production académique des cellules CART conforme aux bonnes pratiques pharmaceutiques (BPF). Recommandations de la Société francophone de greffe de moelle et de thérapie cellulaire (SFGM-TC)

المؤلفون: Deschamps, Marina, Decot, Véronique, Giverne, Camille, Pinturaud, Marine, Vaissié, Alix, Parquet, Nathalie, Olivero, Sylvain, Mamez, Anne-Claire, Bay, Jacques-Olivier, Yakoub-Agha, Ibrahim, Ferrand, Christophe

المصدر: Bulletin du cancer, Vol. 107, No 1S (2020) pp. S85-S93

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______1400::fc3930c51bdf3f23532771b56c7ef998
https://archive-ouverte.unige.ch/unige:154738

View record from ScienceDirect

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CIITA-transduced glioblastoma cells uncover a rich repertoire of clinically relevant tumor-associated HLA-II antigens

المؤلفون: Michal Bassani-Sternberg, Elise Ramia, Brian Stevenson, Greta Forlani, Elodie Lauret Marie Joseph, Michael Linnebacher, Roberto S. Accolla, Florian Huber, HuiSong Pak, Justine Michaux

المصدر: Molecular & Cellular Proteomics : MCP
Molecular & cellular proteomics, vol. 20, pp. 100032

مصطلحات موضوعية: Antigen discovery, CIITA, Cancer Biology, Cancer therapeutics, Glioblastoma, HLA class II, Immunology, Immunopeptidomics, Mass Spectrometry, Tumor antigens, HLA-II, human leukocyte antigen class II, Biochemistry, Epitope, WES, whole-exome sequencing, Analytical Chemistry, APCs, antigen presenting cells, 0303 health sciences, biology, Brain Neoplasms, 030302 biochemistry & molecular biology, a.u., arbitrary units, Nuclear Proteins, TH, T helper cells, 3. Good health, TAAs, tumor-associated antigens, medicine.anatomical_structure, SNPs, single nucleotide polymorphisms, PSM, peptide spectrum match, HLA-I, human leukocyte antigen class I, FDR, false discovery rate, T cell, Class II major histocompatibility complex transactivator, Human leukocyte antigen, Major histocompatibility complex, TcR, T cell receptors, IFNγ, Interferon gamma, ER, endoplasmic reticulum, 03 medical and health sciences, Antigen, Special Issue: Immunopeptidomics, ERAAP, ER aminopeptidase-associated with antigen processing, Antigens, Neoplasm, Cell Line, Tumor, medicine, MHC, major histocompatibility complex, Animals, Humans, Antigen-presenting cell, Molecular Biology, 030304 developmental biology, PBMCs, peripheral blood mononuclear cells, HLA, human leukocyte antigen, Research, T-cell receptor, Histocompatibility Antigens Class II, LFQ, label-free quantification, TAP, transporter-associated with antigen processing, CTL, cytotoxic T cells, CIITA, class II major histocompatibility complex transactivator, HCD, higher-energy collision dissociation, biology.protein, Cancer research, Trans-Activators, Antigens, Neoplasm/immunology, Brain Neoplasms/immunology, Cattle, Glioblastoma/immunology, Histocompatibility Antigens Class II/immunology, Nuclear Proteins/genetics, Nuclear Proteins/immunology, Peptides/immunology, Trans-Activators/genetics, Trans-Activators/immunology, GBM, glioblastoma, Peptides, SNVs, single nucleotide variants

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bfcddca7fc19ba47138689bfadc4b41e
http://hdl.handle.net/11383/2103085

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Chronic TCR-MHC (self)-interactions limit the functional potential of TCR affinity-increased CD8 T lymphocytes

المؤلفون: Nathalie Rufer, Michael Hebeisen, Minh Ngoc Duong, Efe Erdes

المصدر: Journal for ImmunoTherapy of Cancer, Vol 7, Iss 1, Pp 1-17 (2019)
Journal for Immunotherapy of Cancer
Journal for immunotherapy of cancer, vol. 7, no. 1, pp. 284

مصطلحات موضوعية: Cytotoxicity, Immunologic, 0301 basic medicine, Cancer Research, CD3 Complex, Gene Expression, NY-ESO-1 tumor antigen, CD8-Positive T-Lymphocytes, Lymphocyte Activation, Immunotherapy, Adoptive, TCR/CD3 complex, 0302 clinical medicine, Neoplasms, Immunology and Allergy, Cytotoxic T cell, Receptor signaling, T cell function, Receptors, Chimeric Antigen, biology, T cell activation, Chemistry, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, TCR affinity optimization, Cell biology, Cell killing, medicine.anatomical_structure, Antigens, Neoplasm/immunology, CD3 Complex/metabolism, CD8-Positive T-Lymphocytes/immunology, CD8-Positive T-Lymphocytes/metabolism, Cell Line, Tumor, HLA-A2 Antigen/genetics, HLA-A2 Antigen/immunology, HLA-A2 Antigen/metabolism, Humans, Immunophenotyping, Lymphocyte Activation/immunology, Neoplasms/etiology, Neoplasms/metabolism, Neoplasms/therapy, Protein Binding, Receptors, Antigen, T-Cell/genetics, Receptors, Antigen, T-Cell/metabolism, Receptors, Chimeric Antigen/genetics, Receptors, Chimeric Antigen/metabolism, Signal Transduction, CD8 T cells, Immunotherapy, Preclinical study, Oncology, 030220 oncology & carcinogenesis, Molecular Medicine, Research Article, T cell, CD3, Immunology, Receptors, Antigen, T-Cell, chemical and pharmacologic phenomena, Major histocompatibility complex, lcsh:RC254-282, 03 medical and health sciences, Antigen, Antigens, Neoplasm, HLA-A2 Antigen, medicine, Pharmacology, T-cell receptor, 030104 developmental biology, biology.protein, CD8