المؤلفون: Dennis Kirchhoff, Beatrix Stelte-Ludwig, Hans-Georg Lerchen, Antje Margret Wengner, Oliver von Ahsen, Pascale Buchmann, Stephan Märsch, Christoph Mahlert, Simone Greven, Lisa Dietz, Michael Erkelenz, Ruprecht Zierz, Sandra Johanssen, Dominik Mumberg, Anette Sommer

المصدر: Cancers, Vol 12, Iss 11, p 3464 (2020)

مصطلحات موضوعية: acute myeloid leukemia, antibody-drug conjugate, CD123, IL3RA, kinesin spindle protein inhibitor, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282

وصف الملف: electronic resource

Relation: https://www.mdpi.com/2072-6694/12/11/3464; https://doaj.org/toc/2072-6694

URL الوصول: https://doaj.org/article/3654f0b694a240eda2f2d4473f2797ed

المؤلفون: Vignesh Sundararajan, Tuan Zea Tan, Diana Lim, Yanfen Peng, Antje Margret Wengner, Natalie Yan Li Ngoi, Anand D Jeyasekharan, David Shao Peng Tan

المصدر: The Journal of Pathology. 259:194-204

مصطلحات موضوعية: Pathology and Forensic Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::40ed59e0be2918b1d7f7f998e045471a
https://doi.org/10.1002/path.6032

المؤلفون: Benjamin Bader, Sabine Zitzmann-Kolbe, Carl Friedrich Nising, Ulrich Lücking, Qi Wang, Hartmut Rehwinkel, Florian Bartels, Qiuwen Wang, Markus Berger, Antje Margret Wengner, Lars Wortmann, Dieter Moosmayer, Philipp Buchgraber, Hans Briem, Dominik Mumberg, Knut Eis, Uwe Eberspächer, Stefanie Hammer, Christoph A. Schatz, Gerhard Siemeister, Philip Lienau, Ulf Bömer

المصدر: Journal of Medicinal Chemistry. 64:12723-12737

مصطلحات موضوعية: DNA repair, Cell, Antineoplastic Agents, DNA-Activated Protein Kinase, Cell cycle phase, Mice, Phosphatidylinositol 3-Kinases, Structure-Activity Relationship, chemistry.chemical_compound, Cell Line, Tumor, Drug Discovery, medicine, Animals, Humans, Protein kinase A, Cell Proliferation, Molecular Structure, Chemistry, TOR Serine-Threonine Kinases, Drug Synergism, medicine.disease, Xenograft Model Antitumor Assays, In vitro, Rats, medicine.anatomical_structure, Gene Expression Regulation, Ataxia-telangiectasia, Hepatocytes, Cancer research, Molecular Medicine, Drug Therapy, Combination, Homologous recombination, DNA

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::239f4b3d5d418e9f129fce60684625c6
https://doi.org/10.1021/acs.jmedchem.1c00762

المؤلفون: Gerhard Siemeister, Amaury Ernesto Fernandez-Montalvan, Volker K Schulze, Uwe Eberspaecher, Roland Neuhaus, Simon Holton, Stefan Prechtl, Michael Brands, Benjamin Bader, Marian Raschke, Duy Nguyen, Tobias Marquardt, Dirk Kosemund, Detlef Stöckigt, Ulf Bömer, Bertolt Kreft, Hartmut Schirok, Rolf Bohlmann, Antje Margret Wengner, Philip Lienau, Marcus Koppitz, Franz von Nussbaum, Rolf Jautelat, Michael Dr. Brüning, Hans Briem, Dominik Mumberg, Karl Ziegelbauer, Ulrich Klar, Olaf Döhr

المصدر: Journal of Medicinal Chemistry. 63:8025-8042

مصطلحات موضوعية: Male, Programmed cell death, DNA damage, Antineoplastic Agents, Cell Cycle Proteins, Spindle Apparatus, Protein Serine-Threonine Kinases, 01 natural sciences, 03 medical and health sciences, Dogs, Drug Delivery Systems, Cell Line, Tumor, Drug Discovery, medicine, Animals, Humans, Rats, Wistar, Mitosis, 030304 developmental biology, 0303 health sciences, Chemistry, Kinase, Cancer, Protein-Tyrosine Kinases, Cell cycle, medicine.disease, Protein Structure, Tertiary, Rats, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, Spindle checkpoint, Treatment Outcome, Microsomes, Liver, Cancer research, M Phase Cell Cycle Checkpoints, Molecular Medicine, Female, Triazolopyridine, HT29 Cells, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d455cb11862ac96ed455f56494ef1c0a
https://doi.org/10.1021/acs.jmedchem.9b02035

المؤلفون: Philip Lienau, Ellermann Manuel, Stuart L. Schreiber, Stefan Gradl, Martin Lange, Timothy A. Lewis, Luc de Waal, Xiaoyun Wu, Heidi Greulich, Charlotte Kopitz, Willmen Youngsaye, Matthew Meyerson, Antje Margret Wengner

المصدر: ACS Med Chem Lett

مصطلحات موضوعية: biology, 010405 organic chemistry, Chemistry, business.industry, Organic Chemistry, Cancer, Phosphodiesterase, medicine.disease, biology.organism_classification, 01 natural sciences, Biochemistry, Phenotype, 0104 chemical sciences, HeLa, 010404 medicinal & biomolecular chemistry, Text mining, Pharmacokinetics, Drug Discovery, Cancer cell, medicine, Cancer research, Viability assay, business

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0251f22115f85e06b04cdf79c203dd07
https://doi.org/10.1021/acsmedchemlett.9b00360

المؤلفون: Anette Sommer, Katrine Wickstroem, Alexander Kristian, Christine Ellingsen, Dominik Mumberg, Heidrun Ellinger-Ziegelbauer, Olav B. Ryan, Jenny Karlsson, Lars Linden, Antje Margret Wengner, Aasmund Larsen, Else-Marie Hagelin, Roger Smeets, Alan Cuthbertson, Urs B. Hagemann, Roger M. Bjerke, Uta Wirnitzer

المصدر: International Journal of Radiation Oncology*Biology*Physics. 105:410-422

مصطلحات موضوعية: Cancer Research, Immunoconjugates, Cell cycle checkpoint, Ataxia Telangiectasia Mutated Proteins, 030218 nuclear medicine & medical imaging, Histones, Mice, 0302 clinical medicine, Molecular Targeted Therapy, Cytotoxicity, Chelating Agents, Radiation, integumentary system, Thorium, Drug Synergism, Cell cycle, Tumor antigen, Up-Regulation, G2 Phase Cell Cycle Checkpoints, Drug Combinations, Oncology, 030220 oncology & carcinogenesis, musculoskeletal diseases, congenital, hereditary, and neonatal diseases and abnormalities, Cell Survival, DNA damage, Mice, Nude, Breast Neoplasms, Antibodies, Monoclonal, Humanized, 03 medical and health sciences, Cell Line, Tumor, medicine, Animals, Humans, Radiology, Nuclear Medicine and imaging, cardiovascular diseases, Viability assay, Receptor, Fibroblast Growth Factor, Type 2, Protein Kinase Inhibitors, business.industry, Cancer, Radioimmunotherapy, medicine.disease, Xenograft Model Antitumor Assays, stomatognathic diseases, Cell culture, Cancer research, business, DNA Damage, Thorium Compounds

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7faa00ef3067a6eed2af0f1daf71b692
https://doi.org/10.1016/j.ijrobp.2019.06.2508

المؤلفون: Katrine Wickstroem, Gerhard Siemeister, Christine Ellingsen, Alan Cuthbertson, Véronique Cruciani, Urs B. Hagemann, Olav B. Ryan, Karl Ziegelbauer, Jenny Karlsson, Alexander Kristian, Roger M. Bjerke, Lars Linden, Antje Margret Wengner, Dominik Mumberg

المصدر: Journal of Nuclear Medicine. 60:1293-1300

مصطلحات موضوعية: 0301 basic medicine, biology, DNA damage, Chemistry, DNA repair, Poly ADP ribose polymerase, Cancer, medicine.disease, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, 030220 oncology & carcinogenesis, Radionuclide therapy, Cancer cell, Cancer research, medicine, biology.protein, Radiology, Nuclear Medicine and imaging, Mesothelin, Ovarian cancer

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::57b8d74ea4dd855e7c11d73f285f836c
https://doi.org/10.2967/jnumed.118.223701

المؤلفون: Yi Bei, Christian Furth, Koshi Imami, Jana Rolff, Angelika Eggert, Johannes H. Schulte, Jennifer von Stebut, Monika Scheer, Konstantin Helmsauer, Matthias Selbach, Victor Bardinet, Michael V. Ortiz, Heathcliff Dorado Garcia, Andrej Lissat, Dennis Gürgen, Georg Seifert, Patrick Hundsoerfer, Anton G. Henssen, Kerstin Haase, Joachim G. Schulz, Antje Margret Wengner, Fabian Pusch, Marieluise Kirchner, Philipp Mertins, Glorymar Ibáñez, Birgit Lala, Natalie Timme, Ian C. MacArthur, Rocío Chamorro González, Celine Y. Chen

مصطلحات موضوعية: medicine.anatomical_structure, Oncogene, Chemistry, In vivo, Poly ADP ribose polymerase, Cell, Cancer research, medicine, Alveolar rhabdomyosarcoma, Progenitor cell, Rhabdomyosarcoma, medicine.disease, In vitro

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c849f80077ec09157cfcca2492437ef6
https://doi.org/10.1101/2020.12.04.411413

المؤلفون: Sandra Johanssen, Pascale Buchmann, Hans-Georg Lerchen, Christoph Mahlert, Lisa Dietz, Ruprecht Zierz, Dennis Kirchhoff, Antje Margret Wengner, Stephan Märsch, Anette Sommer, Beatrix Stelte-Ludwig, Dominik Mumberg, Michael Erkelenz, Simone Greven, Oliver von Ahsen

المصدر: Cancers
Volume 12
Issue 11
Cancers, Vol 12, Iss 3464, p 3464 (2020)

مصطلحات موضوعية: 0301 basic medicine, Cancer Research, Antibody-drug conjugate, Cell, acute myeloid leukemia, lcsh:RC254-282, Article, antibody-drug conjugate, 03 medical and health sciences, 0302 clinical medicine, In vivo, hemic and lymphatic diseases, medicine, kinesin spindle protein inhibitor, Interleukin 3, IL3RA, biology, business.industry, Myeloid leukemia, lcsh:Neoplasms. Tumors. Oncology. Including cancer and carcinogens, body regions, Haematopoiesis, 030104 developmental biology, medicine.anatomical_structure, Oncology, 030220 oncology & carcinogenesis, CD123, Cancer research, biology.protein, Interleukin-3 receptor, Antibody, business

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::911a4606c808e1a54227263040923acb

المؤلفون: Bernard Haendler, Arne Scholz, Antje Margret Wengner

المصدر: International Journal of Molecular Sciences
International Journal of Molecular Sciences, Vol 21, Iss 8273, p 8273 (2020)

مصطلحات موضوعية: Male, DNA Repair, DNA damage, DNA repair, Estrogen receptor, PARP-1, Breast Neoplasms, Review, Biology, DNA damage response, Medical Oncology, Catalysis, Inorganic Chemistry, lcsh:Chemistry, Prostate cancer, hormone-dependent, breast cancer, medicine, Animals, Humans, Molecular Targeted Therapy, Physical and Theoretical Chemistry, Molecular Biology, Gene, lcsh:QH301-705.5, Spectroscopy, DNA-PKcs, Organic Chemistry, Prostatic Neoplasms, General Medicine, medicine.disease, prostate cancer, Computer Science Applications, radiation, genomic DNA, ATR, lcsh:Biology (General), lcsh:QD1-999, ATM, Cancer cell, Cancer research, Female, DNA Damage, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0f8d6d4d7e58b590865327774e53c155
http://europepmc.org/articles/PMC7663807