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1دورية أكاديمية
المؤلفون: Mikhail Yu. Myshkin, Roope Männikkö, Olesya A. Krumkacheva, Dmitrii S. Kulbatskii, Anton O. Chugunov, Antonina A. Berkut, Alexander S. Paramonov, Mikhail A. Shulepko, Matvey V. Fedin, Michael G. Hanna, Dimitri M. Kullmann, Elena G. Bagryanskaya, Alexander S. Arseniev, Mikhail P. Kirpichnikov, Ekaterina N. Lyukmanova, Alexander A. Vassilevski, Zakhar O. Shenkarev
المصدر: Frontiers in Pharmacology, Vol 10 (2019)
مصطلحات موضوعية: channelopathies, sodium channel, gating modifier, NMR spectroscopy, cell-free expression, combinatorial selective labeling, Therapeutics. Pharmacology, RM1-950
وصف الملف: electronic resource
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المؤلفون: Peter B. Oparin, Anton O. Chugunov, Alyona F. Lihonosova, Antonina A. Berkut, Steve Peigneur, Valentin M. Tabakmakher, Alexander A. Vassilevski, Ekaterina V. Novikova, Konstantin S. Mineev, Roman G. Efremov, Nikolay A. Krylov, Jan Tytgat, Eugene V. Grishin, Alexander S. Arseniev
المصدر: J Biol Chem
مصطلحات موضوعية: 0301 basic medicine, Magnetic Resonance Spectroscopy, Protein Conformation, Surface Properties, Peptide, Molecular Dynamics Simulation, Ligands, Biochemistry, Mass Spectrometry, 03 medical and health sciences, Protein structure, Potassium Channel Blockers, medicine, Animals, Humans, Amino Acid Sequence, Structural motif, Molecular Biology, Ion channel, chemistry.chemical_classification, Kv1.3 Potassium Channel, 030102 biochemistry & molecular biology, Chemistry, Proteins, Computational Biology, Potassium channel blocker, Cell Biology, Potassium channel, 030104 developmental biology, Mutation, Biophysics, Peptides, Selectivity, Protein Binding, medicine.drug, Communication channel
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::876ba469ad7832347896c92267059b31
https://doi.org/10.1074/jbc.ra119.010494 -
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المؤلفون: Roman G. Efremov, Anton O. Chugunov, M. A. Chernykh, Antonina A. Berkut, Nikita A. Kuldyushev, Alexander A. Vassilevski, Steve Peigneur, Jan Tytgat
مصطلحات موضوعية: EXPRESSION, Biochemistry & Molecular Biology, Science & Technology, Chemistry, PROTEINS, Sodium channel, Organic Chemistry, Lysine, Chemistry, Organic, protein engineering, ALPHA-TOXINS, Biochemistry, molecular dynamics, Residue (chemistry), Insect toxin, Glycine, Physical Sciences, Biophysics, Neurotoxin, neurotoxins, voltage-gated sodium channels, Peptide sequence, Life Sciences & Biomedicine, Nest (protein structural motif)
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a01dbe01e6f8724fe8bcaccb6dcd9688
https://lirias.kuleuven.be/handle/20.500.12942/715710 -
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المؤلفون: Nikita A. Kuldyushev, Jan Tytgat, Steve Peigneur, Konstantin S. Mineev, Antonina A. Berkut, Alexander A. Vassilevski, Eugene V. Grishin, Alexander S. Arseniev
المصدر: Proteins: Structure, Function, and Bioinformatics. 86:1117-1122
مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Arginine, Protein Conformation, Stereochemistry, Amino Acid Motifs, Neurotoxins, Scorpion Venoms, Venom, complex mixtures, Biochemistry, Arthropod Proteins, Scorpions, 03 medical and health sciences, Structural Biology, Side chain, Animals, Neurotoxin, Amino Acid Sequence, Structural motif, Molecular Biology, Ion channel, 030102 biochemistry & molecular biology, biology, Chemistry, Sodium channel, biology.organism_classification, 030104 developmental biology, Sequence Alignment, Mesobuthus eupeus
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المؤلفون: Antonina A. Berkut, D.S. Kulbatskii, Elena G. Bagryanskaya, Ekaterina N. Lyukmanova, Mikhail A. Shulepko, Anton O. Chugunov, Olesya A. Krumkacheva, Roope Männikkö, Dimitri M. Kullmann, Zakhar O. Shenkarev, Mikhail P. Kirpichnikov, Matvey V. Fedin, Alexander S. Paramonov, Mikhail Yu. Myshkin, Alexander S. Arseniev, Michael G. Hanna, Alexander A. Vassilevski
المصدر: Frontiers in Pharmacology, Vol 10 (2019)
مصطلحات موضوعية: 0301 basic medicine, Gating, law.invention, 03 medical and health sciences, NMR spectroscopy, 0302 clinical medicine, law, Pharmacology (medical), Binding site, Electron paramagnetic resonance, Protein secondary structure, Pharmacology, Chemistry, Sodium channel, lcsh:RM1-950, cell-free expression, gating modifier, Nuclear magnetic resonance spectroscopy, channelopathies, Spider toxin, lcsh:Therapeutics. Pharmacology, 030104 developmental biology, combinatorial selective labeling, Docking (molecular), 030220 oncology & carcinogenesis, Biophysics, sodium channel
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d9b0c5d36f6d3f0fb3041eea491f274b
https://doi.org/10.3389/fphar.2019.00953 -
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المؤلفون: Michael G. Hanna, Antonina A. Berkut, Stephanie Schorge, Roope Männikkö, Dimitri M. Kullmann, Dmitry Kuzmin, D.S. Kulbatskii, Michael G. Thor, Emma R. Wilson, Alexander S. Paramonov, Alexander A. Vassilevski, Zakhar O. Shenkarev, Frank Bosmans, Marisol Sampedro Castañeda, Mikhail Yu. Myshkin, Ekaterina N. Lyukmanova, Louise King, Mikhail P. Kirpichnikov
المصدر: Proceedings of the National Academy of Sciences of the United States of America
مصطلحات موضوعية: 0301 basic medicine, hypokalemic periodic paralysis, Neurotoxins, Mutation, Missense, Spider Venoms, Gating, Protein Structure, Secondary, 03 medical and health sciences, Xenopus laevis, channelopathy, Channelopathy, medicine, Neurotoxin, Animals, Humans, NAV1.4 Voltage-Gated Sodium Channel, Ion channel, Multidisciplinary, Chemistry, Sodium channel, Periodic paralysis, Depolarization, neurotoxin, gating modifier, Biological Sciences, medicine.disease, Spider toxin, 3. Good health, 030104 developmental biology, HEK293 Cells, Amino Acid Substitution, Biophysics, Female, Ion Channel Gating, Paralysis, Hyperkalemic Periodic, Neuroscience, sodium channel
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2cbd146f10ccda3c469e9fb5df178df0
http://europepmc.org/articles/PMC5924911 -
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المؤلفون: Eugene V. Grishin, Daniil Osipov, Antonina A. Berkut, Alexander A. Vassilevski, Evgeniia Lagereva, Anfisa Popova, Alexander Andreev-Andrievskiy
المصدر: Toxicon. 138:59-67
مصطلحات موضوعية: Male, Xylazine, 0301 basic medicine, Chlorpromazine, Poecilotheria, Oxcarbazepine, Spider Venoms, Stereotypic Movement Disorder, Venom, Voltage-Gated Sodium Channels, Pharmacology, Toxicology, 03 medical and health sciences, 0302 clinical medicine, Seizures, Spider Bites, medicine, Animals, Envenomation, Muscle Cramp, Mice, Inbred BALB C, 030102 biochemistry & molecular biology, biology, business.industry, Spider bites, biology.organism_classification, medicine.disease, Stereotypy (non-human), Hyperalgesia, medicine.symptom, business, 030217 neurology & neurosurgery, Muscle cramp, medicine.drug
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المؤلفون: Eugene V. Grishin, Antonina A. Berkut, Alexander A. Vassilevski, Jan Tytgat, Steve Peigneur, Nikita A. Kuldyushev
المصدر: FEBS Letters. 591:3414-3420
مصطلحات موضوعية: Models, Molecular, 0301 basic medicine, Gene isoform, Insecta, Recombinant Fusion Proteins, Neurotoxins, Biophysics, Gene Expression, Scorpion Venoms, Biology, Protein Engineering, Biochemistry, Protein Structure, Secondary, Substrate Specificity, Scorpions, Mice, Structure-Activity Relationship, Xenopus laevis, 03 medical and health sciences, Thioredoxins, Structural Biology, Escherichia coli, Genetics, Animals, Humans, Neurotoxin, Structure–activity relationship, Protein Interaction Domains and Motifs, Amino Acid Sequence, Cloning, Molecular, Binding site, Molecular Biology, Binding Sites, NAV1.2 Voltage-Gated Sodium Channel, Sequence Homology, Amino Acid, Sodium channel, Cell Biology, biology.organism_classification, 030104 developmental biology, Oocytes, Selectivity, Sequence Alignment, Mesobuthus eupeus, Protein Binding
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المؤلفون: Eugene V. Grishin, Peter B. Oparin, Antonina A. Berkut, Alexander S. Arseniev, Alexander A. Vassilevski, Kirill D. Nadezhdin
المصدر: Biochemical Journal. 473:3113-3126
مصطلحات موضوعية: 0301 basic medicine, Magnetic Resonance Spectroscopy, Sequence analysis, Spider Venoms, Microbial Sensitivity Tests, Biology, Biochemistry, Mass Spectrometry, Protein Structure, Secondary, 03 medical and health sciences, medicine, Amino Acid Sequence, Mode of action, Molecular Biology, Sequence Homology, Amino Acid, 030102 biochemistry & molecular biology, Voltage-dependent calcium channel, Ecology, Circular Dichroism, Cell Membrane, Cell Biology, 030104 developmental biology, Membrane, Mechanism of action, Helix, Biophysics, Inhibitor cystine knot, Target protein, medicine.symptom
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::234ef52248f0c09b0f9bff8fd9d11f71
https://doi.org/10.1042/bcj20160573 -
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المؤلفون: Mikhail P. Kirpichnikov, Alexander A. Vassilevski, Zakhar O. Shenkarev, Jan Tytgat, M. Yu. Myshkin, Ekaterina N. Lyukmanova, Antonina A. Berkut, Steve Peigneur, Mikhail A. Shulepko
المصدر: Doklady. Biochemistry and biophysics. 484(1)
مصطلحات موضوعية: Tityus serrulatus, Biophysics, Muscle Proteins, Scorpion Venoms, Venom, medicine.disease_cause, Biochemistry, Inclusion bodies, Protein Structure, Secondary, Sodium Channels, law.invention, NAV1.5 Voltage-Gated Sodium Channel, 03 medical and health sciences, Structure-Activity Relationship, Xenopus laevis, law, medicine, Animals, Humans, NAV1.4 Voltage-Gated Sodium Channel, Escherichia coli, Nuclear Magnetic Resonance, Biomolecular, 030304 developmental biology, Membrane potential, 0303 health sciences, biology, Toxin, Chemistry, Sodium channel, 030302 biochemistry & molecular biology, General Chemistry, General Medicine, biology.organism_classification, Recombinant Proteins, Rats, Recombinant DNA, Sodium Channel Blockers