المؤلفون: Nasser A; Formerly with Supernus Pharmaceuticals, Inc., 9715 Key West Ave, Rockville, MD, 20850, USA. anasser25@gmail.com., Gomeni R; PharmacoMetrica, Lieu-dit Longcol, La Fouillade, France., Ceresoli-Borroni G; Supernus Pharmaceuticals, Inc., Rockville, MD, USA., Xie L; Formerly with Supernus Pharmaceuticals, Inc., 9715 Key West Ave, Rockville, MD, 20850, USA., Busse GD; Formerly with Supernus Pharmaceuticals, Inc., 9715 Key West Ave, Rockville, MD, 20850, USA., Melyan Z; Formerly with Supernus Pharmaceuticals, Inc., 9715 Key West Ave, Rockville, MD, 20850, USA., Rubin J; Supernus Pharmaceuticals, Inc., Rockville, MD, USA.

المصدر: Journal of pharmacokinetics and pharmacodynamics [J Pharmacokinet Pharmacodyn] 2024 Aug; Vol. 51 (4), pp. 385-393. Date of Electronic Publication: 2024 Apr 05.

نوع المنشور: Journal Article; Comparative Study

بيانات الدورية: Publisher: Springer Country of Publication: United States NLM ID: 101096520 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-8744 (Electronic) Linking ISSN: 1567567X NLM ISO Abbreviation: J Pharmacokinet Pharmacodyn Subsets: MEDLINE

مواضيع طبية MeSH: Apomorphine*/administration & dosage , Apomorphine*/pharmacokinetics , Parkinson Disease*/drug therapy , Models, Biological*, Humans ; Administration, Sublingual ; Injections, Subcutaneous ; Antiparkinson Agents/pharmacokinetics ; Antiparkinson Agents/administration & dosage ; Antiparkinson Agents/therapeutic use ; Computer Simulation ; Dose-Response Relationship, Drug

المؤلفون: Bardgett ME; Department of Psychological Science, Northern Kentucky University, Highland Heights, KY 41076, United States. Electronic address: bardgettm@nku.edu., Griffith MS; Department of Psychological Science, Northern Kentucky University, Highland Heights, KY 41076, United States., Robinson KR; Department of Psychological Science, Northern Kentucky University, Highland Heights, KY 41076, United States., Stevens RM; Department of Psychological Science, Northern Kentucky University, Highland Heights, KY 41076, United States., Gannon MA; Department of Psychological Science, Northern Kentucky University, Highland Heights, KY 41076, United States., Knuth MD; Department of Psychological Science, Northern Kentucky University, Highland Heights, KY 41076, United States., Hawk GS; Department of Statistics, College of Arts and Sciences, University of Kentucky, Lexington, KY 40504, United States; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, KY 40504, United States., Pauly JR; Department of Statistics, College of Arts and Sciences, University of Kentucky, Lexington, KY 40504, United States; Department of Pharmaceutical Sciences, College of Pharmacy, University of Kentucky, Lexington, KY 40504, United States.

المصدر: Behavioural brain research [Behav Brain Res] 2024 Sep 13; Vol. 473, pp. 115171. Date of Electronic Publication: 2024 Jul 31.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 8004872 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7549 (Electronic) Linking ISSN: 01664328 NLM ISO Abbreviation: Behav Brain Res Subsets: MEDLINE

مواضيع طبية MeSH: Apomorphine*/pharmacology , Apomorphine*/administration & dosage , Risperidone*/pharmacology , Risperidone*/administration & dosage , Quinpirole*/pharmacology , Rats, Long-Evans* , Dopamine Agonists*/pharmacology , Dopamine Agonists*/administration & dosage , Motor Activity*/drug effects , Antipsychotic Agents*/pharmacology , Antipsychotic Agents*/administration & dosage, Animals ; Rats ; Female ; Male ; Dose-Response Relationship, Drug ; Receptors, Dopamine D2/metabolism ; Receptors, Dopamine D2/drug effects ; Animals, Newborn ; Age Factors ; Sex Factors

المؤلفون: Ikram H; Neurochemistry and Biochemical Neuropharmacology Research Unit, Department of Biochemistry, University of Karachi, Karachi, 75270, Pakistan. hikram@uok.edu.pk., Zakir R; Neurochemistry and Biochemical Neuropharmacology Research Unit, Department of Biochemistry, University of Karachi, Karachi, 75270, Pakistan., Haleem DJ; Neurochemistry and Biochemical Neuropharmacology Research Unit, Department of Biochemistry, University of Karachi, Karachi, 75270, Pakistan.; Neuroscience Research Laboratory, Dr Panjwani Center for Molecular Medicine and Drug Research-ICCBS, University of Karachi, Karachi, 75270, Pakistan.

المصدر: Metabolic brain disease [Metab Brain Dis] 2024 Aug; Vol. 39 (6), pp. 1051-1063. Date of Electronic Publication: 2024 Jun 19.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Springer Country of Publication: United States NLM ID: 8610370 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-7365 (Electronic) Linking ISSN: 08857490 NLM ISO Abbreviation: Metab Brain Dis Subsets: MEDLINE

مواضيع طبية MeSH: Apomorphine*/pharmacology , Neuroprotective Agents*/pharmacology , Neuroprotective Agents*/therapeutic use , Dementia*/drug therapy , Dementia*/metabolism , Dementia*/prevention & control , Disease Models, Animal* , Rats, Wistar* , Scopolamine* , Memory*/drug effects, Animals ; Rats ; Male ; Oxidative Stress/drug effects ; Brain/metabolism ; Brain/drug effects ; Catalase/metabolism ; Superoxide Dismutase/metabolism ; Lipid Peroxidation/drug effects ; Acetylcholinesterase/metabolism ; Glutathione Peroxidase/metabolism ; Antioxidants/pharmacology ; Antioxidants/therapeutic use

المؤلفون: Serra M; Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy., Marongiu J; Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy., Simola N; Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy. Electronic address: nicola.simola@unica.it., Costa G; Department of Biomedical Sciences, University of Cagliari, Cagliari, Italy.

المصدر: Experimental neurology [Exp Neurol] 2024 Nov; Vol. 381, pp. 114939. Date of Electronic Publication: 2024 Aug 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 0370712 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2430 (Electronic) Linking ISSN: 00144886 NLM ISO Abbreviation: Exp Neurol Subsets: MEDLINE

مواضيع طبية MeSH: Vocalization, Animal*/drug effects , Antiparkinson Agents*/pharmacology , Apomorphine*/pharmacology , Levodopa*/pharmacology, Animals ; Rats ; Male ; Parkinsonian Disorders/drug therapy ; Parkinsonian Disorders/chemically induced ; Early Growth Response Protein 1/metabolism ; Neurons/drug effects ; Rats, Wistar ; Affect/drug effects ; Prefrontal Cortex/drug effects ; Prefrontal Cortex/metabolism ; Oxidopamine/toxicity ; Dopamine Agonists/pharmacology

المؤلفون: Kassubek J; Department of Neurology, University Hospital Ulm, Oberer Eselsberg 45, 89081, Ulm, Germany. jan.kassubek@uni-ulm.de.; German Centre for Neurodegenerative Diseases, Ulm, Germany. jan.kassubek@uni-ulm.de., Factor SA; Jean and Paul Amos Parkinson's Disease and Movement Disorder Program, Emory University School of Medicine, Atlanta, GA, USA., Balaguer E; Hospital Universitari General de Catalunya, Barcelona, Spain., Schwarz J; Department of Geriatrics, Kreisklinik Ebersberg, Ebersberg, Germany., Chaudhuri KR; Department of Neurosciences, Institute of Psychiatry, Psychology and Neuroscience and Parkinson's Foundation Centre of Excellence, King's College Hospital, King's College London, London, UK., Isaacson SH; Parkinson's Disease and Movement Disorders Center of Boca Raton, Boca Raton, FL, USA., Wu S; Sumitomo Pharma America, Inc., Marlborough, MA, USA., Denecke Muhr C; BIAL-Portela & Ca S.A., Porto, Portugal., Kulisevsky J; Hospital de la Santa Creu i Sant Pau, Barcelona, Spain.; Universitat Autònoma de Barcelona and CIBERNED, Madrid, Spain.

المصدر: Journal of neurology [J Neurol] 2024 Jun; Vol. 271 (6), pp. 3554-3570. Date of Electronic Publication: 2024 Mar 28.

نوع المنشور: Journal Article; Clinical Trial, Phase III; Multicenter Study

بيانات الدورية: Publisher: Springer-Verlag Country of Publication: Germany NLM ID: 0423161 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-1459 (Electronic) Linking ISSN: 03405354 NLM ISO Abbreviation: J Neurol Subsets: MEDLINE

مواضيع طبية MeSH: Parkinson Disease*/drug therapy , Parkinson Disease*/complications , Apomorphine*/administration & dosage , Apomorphine*/adverse effects , Apomorphine*/pharmacology , Antiparkinson Agents*/administration & dosage , Antiparkinson Agents*/adverse effects, Humans ; Male ; Female ; Middle Aged ; Aged ; Administration, Sublingual ; Treatment Outcome

المؤلفون: Hislop J; Department of Neurology, University of Miami Miller School of Medicine, Miami, Florida, USA., Margolesky J; Department of Neurology, University of Miami Miller School of Medicine, Miami, Florida, USA., Shpiner DS; Department of Neurology, University of Miami Miller School of Medicine, Miami, Florida, USA.

المصدر: The International journal of neuroscience [Int J Neurosci] 2024 May; Vol. 134 (5), pp. 474-480. Date of Electronic Publication: 2022 Aug 24.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Informa Healthcare Country of Publication: England NLM ID: 0270707 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1563-5279 (Electronic) Linking ISSN: 00207454 NLM ISO Abbreviation: Int J Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Apomorphine*/administration & dosage , Apomorphine*/pharmacology , Apomorphine*/adverse effects , Parkinson Disease*/drug therapy , Antiparkinson Agents*/administration & dosage , Antiparkinson Agents*/adverse effects, Humans ; Administration, Sublingual

المؤلفون: Chan TT, Gonzalez AL, Lyons BM

المصدر: Journal of the American Veterinary Medical Association [J Am Vet Med Assoc] 2024 Apr 12; Vol. 262 (7), pp. 924-927. Date of Electronic Publication: 2024 Apr 12 (Print Publication: 2024).

نوع المنشور: Journal Article; Randomized Controlled Trial, Veterinary

بيانات الدورية: Publisher: American Veterinary Medical Association Country of Publication: United States NLM ID: 7503067 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1943-569X (Electronic) Linking ISSN: 00031488 NLM ISO Abbreviation: J Am Vet Med Assoc Subsets: MEDLINE

مواضيع طبية MeSH: Vomiting*/veterinary , Apomorphine*/administration & dosage , Apomorphine*/therapeutic use , Dog Diseases*/drug therapy, Animals ; Dogs ; Female ; Male ; Emetics/therapeutic use ; Emetics/administration & dosage

المؤلفون: Thijssen E; Centre for Human Drug Research (CHDR), Leiden, The Netherlands.; Leiden University Medical Centre (LUMC), Leiden, The Netherlands., Tuk B; Criceto IKM, Casteren, The Netherlands., Cakici M; Centre for Human Drug Research (CHDR), Leiden, The Netherlands.; Leiden University Medical Centre (LUMC), Leiden, The Netherlands., van Velze V; Centre for Human Drug Research (CHDR), Leiden, The Netherlands.; Leiden University Medical Centre (LUMC), Leiden, The Netherlands., Klaassen E; Centre for Human Drug Research (CHDR), Leiden, The Netherlands., Merkus F; Innotesto BV, Kasterlee, Belgium., van Laar T; Groningen University Medical Center (UMCG), Groningen, The Netherlands., Kremer P; Centre for Human Drug Research (CHDR), Leiden, The Netherlands.; Leiden University Medical Centre (LUMC), Leiden, The Netherlands., Groeneveld GJ; Centre for Human Drug Research (CHDR), Leiden, The Netherlands.; Leiden University Medical Centre (LUMC), Leiden, The Netherlands.

المصدر: Clinical and translational science [Clin Transl Sci] 2024 May; Vol. 17 (5), pp. e13796.

نوع المنشور: Clinical Study; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print Cited Medium: Internet ISSN: 1752-8062 (Electronic) Linking ISSN: 17528054 NLM ISO Abbreviation: Clin Transl Sci Subsets: MEDLINE

مواضيع طبية MeSH: Apomorphine*/administration & dosage , Apomorphine*/pharmacokinetics , Apomorphine*/adverse effects , Parkinson Disease*/drug therapy, Aged ; Female ; Humans ; Male ; Middle Aged ; Administration, Oral ; Administration, Sublingual ; Antiparkinson Agents/administration & dosage ; Antiparkinson Agents/pharmacokinetics ; Antiparkinson Agents/adverse effects ; Biological Availability ; Cross-Over Studies ; Dose-Response Relationship, Drug ; Injections, Subcutaneous ; Adult ; Aged, 80 and over

المؤلفون: Song Z; Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI, 48201, USA., Wang KW; Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, 48824, USA., Hagar HC; Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, 48824, USA., Chen HR; Department of Neuroscience, School of Medicine, University of Virginia, Charlottesville, VA, 22903, USA.; Present address: Department of Life Sciences and Institute of Genome Sciences, National Yang Ming Chiao Tung University, Taipei, Taiwan, 112304., Kuan CY; Department of Neuroscience, School of Medicine, University of Virginia, Charlottesville, VA, 22903, USA., Zhang K; Center for Molecular Medicine and Genetics, Wayne State University School of Medicine, Detroit, MI, 48201, USA. kzhang@med.wayne.edu., Kuo MH; Department of Biochemistry and Molecular Biology, Michigan State University, East Lansing, MI, 48824, USA. kuom@msu.edu.

المصدر: Molecular neurobiology [Mol Neurobiol] 2024 May; Vol. 61 (5), pp. 2653-2671. Date of Electronic Publication: 2023 Nov 03.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Humana Press Country of Publication: United States NLM ID: 8900963 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1559-1182 (Electronic) Linking ISSN: 08937648 NLM ISO Abbreviation: Mol Neurobiol Subsets: MEDLINE

مواضيع طبية MeSH: tau Proteins*/metabolism , Endoplasmic Reticulum Stress*/drug effects , Apomorphine*/pharmacology, Phosphorylation/drug effects ; Humans ; Apoptosis/drug effects ; Unfolded Protein Response/drug effects ; Heme Oxygenase-1/metabolism ; Intracellular Space/metabolism ; Intracellular Space/drug effects ; Animals ; Calcium/metabolism ; Inflammation/pathology ; Inflammation/metabolism ; Inflammation/drug therapy

المؤلفون: Ando D; Division of Drugs, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa, 210-9501, Japan. ando-daisuke@nihs.go.jp., Ozawa A; Laboratory of Anatomy II, Department of Veterinary Medicine, School of Veterinary Medicine, Azabu University, Sagamihara, Kanagawa, 252-5201, Japan., Sakaue M; Laboratory of Anatomy II, Department of Veterinary Medicine, School of Veterinary Medicine, Azabu University, Sagamihara, Kanagawa, 252-5201, Japan., Yamamoto E; Division of Drugs, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa, 210-9501, Japan.; Division of Medical Devices, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa, 210-9501, Japan., Miyazaki T; Division of Drugs, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa, 210-9501, Japan., Sato Y; Division of Drugs, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa, 210-9501, Japan., Koide T; Division of Drugs, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa, 210-9501, Japan., Izutsu KI; Division of Drugs, National Institute of Health Sciences, 3-25-26 Tonomachi, Kawasaki-ku, Kawasaki, Kanagawa, 210-9501, Japan.; Department of Pharmaceutical Sciences, School of Pharmacy, International University of Health and Welfare, 2600-1 Kitakanemaru, Ohtawara, Tochigi, 324-8501, Japan.

المصدر: Pharmaceutical research [Pharm Res] 2024 Jan; Vol. 41 (1), pp. 153-163. Date of Electronic Publication: 2023 Nov 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Kluwer Academic/Plenum Publishers Country of Publication: United States NLM ID: 8406521 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-904X (Electronic) Linking ISSN: 07248741 NLM ISO Abbreviation: Pharm Res Subsets: MEDLINE

مواضيع طبية MeSH: Apomorphine*/pharmacology , Parkinson Disease*/drug therapy, Rats ; Animals ; Drug Delivery Systems ; Administration, Cutaneous ; Skin