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المؤلفون: April D Lake, Kevin Holsapple, Tanya McDonnell, Joseph C Arezzo, Ricardo Ramirez, Lindsay Gamelin, Mei Yu, Dylan Glatt, Ryan Dick, Xiaodong Xie, Regina Choy, Guofeng Cheng, Chin H Tay, Anne Chester, Darryl Kato, Leigh Ann Burns-Naas
المصدر: Toxicological Sciences. 186:298-308
مصطلحات موضوعية: Hepatitis B virus, Administration, Oral, Animals, Haplorhini, Rats, Wistar, Toxicology, Antiviral Agents, Rats, Retrospective Studies
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::72019e0b0b0a251453a80ddac1615d2b
https://doi.org/10.1093/toxsci/kfac009 -
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المؤلفون: Dean Billheimer, Elmira Torabzadeh, Zhengqiang Lu, Nelly Aranibar, April D. Lake, Michael D. Reily, Nathan J. Cherrington, Lois D. Lehman-McKeeman, Hui Li, Donald G. Robertson, Jian Hua Han, Petr Novák, Anika L. Dzierlenga, Petia Shipkova
المصدر: Obesity. 25:1069-1076
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Pathology, medicine.drug_class, Endocrinology, Diabetes and Metabolism, Metabolite, Medicine (miscellaneous), Biology, digestive system, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Endocrinology, Metabolomics, Internal medicine, Nonalcoholic fatty liver disease, medicine, Metabolome, Nutrition and Dietetics, Methionine, Bile acid, Cholic acid, nutritional and metabolic diseases, medicine.disease, digestive system diseases, 3. Good health, 030104 developmental biology, chemistry, 030211 gastroenterology & hepatology, Steatosis
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المصدر: Liver International. 37:1074-1081
مصطلحات موضوعية: 0301 basic medicine, Glycosylation, Blotting, Western, Biology, Endoplasmic Reticulum, Article, 03 medical and health sciences, chemistry.chemical_compound, N-linked glycosylation, Non-alcoholic Fatty Liver Disease, Gene expression, medicine, Humans, Hepatology, Gene Expression Profiling, Multidrug resistance-associated protein 2, Fatty liver, Membrane Transport Proteins, Biological Transport, Transporter, medicine.disease, carbohydrates (lipids), 030104 developmental biology, Liver, Oligosaccharyltransferase complex, Biochemistry, chemistry, Case-Control Studies, Efflux, Transcriptome, Protein Processing, Post-Translational
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المؤلفون: Nathan J. Cherrington, Rhiannon N. Hardwick, Christopher P. Leamon, Philip S. Low, April D. Lake
مصطلحات موضوعية: 0301 basic medicine, Male, Toxicology, Rats, Sprague-Dawley, chemistry.chemical_compound, 0302 clinical medicine, Methionine, Non-alcoholic Fatty Liver Disease, Nonalcoholic fatty liver disease, Choline, education.field_of_study, Organotechnetium Compounds, Imaging agent, Choline Deficiency, Molecular Imaging, Liver, 030220 oncology & carcinogenesis, medicine.symptom, medicine.medical_specialty, Inflammation, Biology, Diet, High-Fat, digestive system, Article, 03 medical and health sciences, Folic Acid, Predictive Value of Tests, Internal medicine, medicine, Animals, Humans, Folate Receptor 2, education, Pharmacology, Tomography, Emission-Computed, Single-Photon, Folate receptor beta, Innate immune system, Macrophages, nutritional and metabolic diseases, medicine.disease, digestive system diseases, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, Endocrinology, chemistry, Steatosis, Radiopharmaceuticals, Biomarkers
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ff03ce446fa46b12082ec1853c26b6b8
https://europepmc.org/articles/PMC6487882/ -
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المؤلفون: Beth Padnos, Alan H. Tennant, Charlene A. McQueen, Charles E. Wood, Jane Ellen Simmons, Michael F. Hughes, April D. Lake, David G. Ross, Yusupha M. Sey, J. Christopher Corton, Barbara Jane George, Susan D. Hester, Brian N. Chorley, Elaina M. Kenyon, Tanya Moore, Gleta Carswell, Virunya S. Bhat, Judith E. Schmid
المصدر: Toxicological Sciences. 149:312-325
مصطلحات موضوعية: Male, 0301 basic medicine, medicine.medical_specialty, Liver tumor, Phthalic Acids, Peroxisome proliferator-activated receptor, Alpha (ethology), Biology, Pharmacology, Toxicology, Polymerase Chain Reaction, Mice, 03 medical and health sciences, chemistry.chemical_compound, Liver Neoplasms, Experimental, Diethylhexyl Phthalate, Internal medicine, medicine, Animals, PPAR alpha, Mode of action, Cell Proliferation, chemistry.chemical_classification, Dose-Response Relationship, Drug, Liver cell, Body Weight, Phthalate, medicine.disease, Benchmarking, Oxidative Stress, 030104 developmental biology, Endocrinology, Liver, chemistry, Toxicity, Linear Models, Peroxisome proliferator-activated receptor alpha
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dfb69e26a93f395a9d9e922003f52486
https://doi.org/10.1093/toxsci/kfv236 -
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المؤلفون: Susan D. Hester, Elias T. Gaillard, Tanya Moore, Michael H. George, Charles E. Wood, William O. Ward, Carlin Okerberg, Anthony B. DeAngelo, Anna Fisher, Brian N. Chorley, April D. Lake, Hongzu Ren, Gleta Carswell, Beena Vallanat
المصدر: Carcinogenesis. 36:782-791
مصطلحات موضوعية: Male, Cancer Research, medicine.medical_specialty, Liver tumor, Mice, Inbred Strains, Dichloroacetic acid, Biology, medicine.disease_cause, Eating, chemistry.chemical_compound, Internal medicine, medicine, Animals, RNA, Messenger, Carcinogen, Dichloroacetic Acid, Dose-Response Relationship, Drug, Liver Neoplasms, General Medicine, Metabolism, DNA Methylation, medicine.disease, Gene Expression Regulation, Neoplastic, MicroRNAs, Endocrinology, chemistry, Phenobarbital, Immunology, Environmental Pollutants, Female, Histopathology, Liver cancer, Carcinogenesis, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::039d62494e0a2953649a5fa06d27d195
https://doi.org/10.1093/carcin/bgv057 -
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المؤلفون: Michael Goedken, John D. Clarke, Nathan J. Cherrington, Curtis D. Klaassen, April D. Lake, Rhiannon N. Hardwick, Andrew J. Lickteig
المصدر: Journal of Hepatology. 61:139-147
مصطلحات موضوعية: Male, Statin, Organic anion transporter 1, medicine.drug_class, Biological Transport, Active, Organic Anion Transporters, Organic Anion Transporters, Sodium-Independent, Pharmacology, Article, Choline, Mice, chemistry.chemical_compound, Methionine, Pharmacokinetics, Non-alcoholic Fatty Liver Disease, medicine, Animals, Humans, Pravastatin, Mice, Knockout, Hepatology, biology, Liver-Specific Organic Anion Transporter 1, Muscles, nutritional and metabolic diseases, Transporter, medicine.disease, Mice, Inbred C57BL, Organic anion-transporting polypeptide, Liver, chemistry, biology.protein, Hydroxymethylglutaryl-CoA Reductase Inhibitors, Steatohepatitis, medicine.drug
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المصدر: Journal of Pharmacology and Experimental Therapeutics. 348:452-458
مصطلحات موضوعية: Male, Simvastatin, medicine.medical_specialty, Organic anion transporter 1, Down-Regulation, Organic Anion Transporters, Metabolism, Transport, and Pharmacogenomics, Rats, Sprague-Dawley, chemistry.chemical_compound, Non-alcoholic Fatty Liver Disease, Internal medicine, Nonalcoholic fatty liver disease, medicine, Animals, Myopathy, Pharmacology, Methionine, biology, Fatty liver, medicine.disease, digestive system diseases, Rats, Fatty Liver, Organic anion-transporting polypeptide, Endocrinology, Liver, chemistry, biology.protein, Molecular Medicine, Hydroxymethylglutaryl-CoA Reductase Inhibitors, medicine.symptom, SLCO1B1, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5de960008959ae49c2632ed6131de4f6
https://doi.org/10.1124/jpet.113.211284 -
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المؤلفون: Petr Novák, Catharine L. Smith, Alexandria L. Chaput, Nathan J. Cherrington, April D. Lake
مصطلحات موضوعية: 0301 basic medicine, medicine.medical_specialty, Peroxisome proliferator-activated receptor, Down-Regulation, Biology, Biochemistry, digestive system, Article, 03 medical and health sciences, Non-alcoholic Fatty Liver Disease, Internal medicine, Gene expression, medicine, Humans, Liver X receptor, Transcription factor, Pharmacology, Regulation of gene expression, chemistry.chemical_classification, Binding Sites, Gene Expression Profiling, nutritional and metabolic diseases, digestive system diseases, Up-Regulation, DNA binding site, Gene expression profiling, 030104 developmental biology, Endocrinology, chemistry, Nuclear receptor, Gene Expression Regulation, Cancer research, Disease Progression, Protein Binding, Transcription Factors
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bcdd8bc79852116d53c86dd70a6aa113
https://europepmc.org/articles/PMC5129657/ -
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المؤلفون: John D. Clarke, April D. Lake, Eric Blomme, Nathan J. Cherrington, Jonathan M. Maher, Tatiana Sharapova
المصدر: Journal of Applied Toxicology. 34:726-732
مصطلحات موضوعية: Liver injury, medicine.medical_specialty, Pathology, Cirrhosis, Fatty liver, Biology, Toxicology, medicine.disease, digestive system, digestive system diseases, Transaminase, chemistry.chemical_compound, Endocrinology, chemistry, Alanine transaminase, Internal medicine, medicine, biology.protein, Choline, Biomarker (medicine), Steatohepatitis