المؤلفون: J Robert Lane, Ara M Abramyan, Pramisha Adhikari, Alastair C Keen, Kuo-Hao Lee, Julie Sanchez, Ravi Kumar Verma, Herman D Lim, Hideaki Yano, Jonathan A Javitch, Lei Shi

المصدر: eLife, Vol 9 (2020)

مصطلحات موضوعية: dopamine d2 receptor, na+ sensitivity, inverse agonism, molecular dynamics, Medicine, Science, Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: https://elifesciences.org/articles/52189; https://doaj.org/toc/2050-084X

URL الوصول: https://doaj.org/article/22ae5702392642ec91760a357236acbd

المؤلفون: Ravi Kumar Verma, Ara M Abramyan, Mayako Michino, R Benjamin Free, David R Sibley, Jonathan A Javitch, J Robert Lane, Lei Shi

المصدر: PLoS Computational Biology, Vol 14, Iss 1, p e1005948 (2018)

مصطلحات موضوعية: Biology (General), QH301-705.5

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC5786319?pdf=render; https://doaj.org/toc/1553-734X; https://doaj.org/toc/1553-7358

URL الوصول: https://doaj.org/article/c32595f0cebf4f86b145258df520dd63

المؤلفون: Noah X. Hamlish, Ara M. Abramyan, Bhavana Shah, Zhongqi Zhang, Alanna Schepartz

المصدر: ACS Central Science, Vol 10, Iss 5, Pp 1044-1053 (2024)

مصطلحات موضوعية: Chemistry, QD1-999

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2374-7951

URL الوصول: https://doaj.org/article/dc2e4eb49e3a478e8d308603d8956dad

المؤلفون: Zoe L. Watson, Isaac Knudson, Fred R. Ward, Scott J. Miller, Jamie H. D. Cate, Alanna Schepartz, Ara M. Abramyan

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::cf3a15e66d52e2a3452ba1937f3d98c3
https://doi.org/10.1101/2022.08.13.503842

المؤلفون: Disha M. Gandhi, Ara M. Abramyan, Xin Hu, Jeffrey Aubé, Kevin J. Frankowski, David R. Sibley, Emmanuel Akano, Lei Shi, Joseph P. Steiner, Thomas M. Keck, Marc Ferrer, Amy E. Moritz, R. Benjamin Free, Warren S. Weiner, Noel Southall

المصدر: J Med Chem

مصطلحات موضوعية: Male, Agonist, medicine.drug_class, G protein, Induced Pluripotent Stem Cells, CHO Cells, Pharmacology, Article, Protein Structure, Secondary, Mice, Cricetulus, Dopamine receptor D3, Drug Discovery, medicine, Animals, Humans, Receptor, Dose-Response Relationship, Drug, Chemistry, Dopaminergic, Neurodegeneration, Receptors, Dopamine D3, Hep G2 Cells, medicine.disease, Mice, Inbred C57BL, HEK293 Cells, Dopamine receptor, Dopamine Agonists, Molecular Medicine, Phosphorylation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::71df63d947d47819d658d465cac70a62
https://doi.org/10.1021/acs.jmedchem.0c00424

المؤلفون: Ara M. Abramyan, Leanne Liu, Min Xu, Hideaki Yano, Andrew D. Fant, Sett Naing, Lei Shi

المصدر: Computational and Structural Biotechnology Journal, Vol 18, Iss, Pp 199-206 (2020)
Computational and Structural Biotechnology Journal

مصطلحات موضوعية: lcsh:Biotechnology, Biophysics, Western blot, Trimer, Bioluminescence resonance energy transfer, medicine.disease_cause, Biochemistry, Oligomer, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Structural Biology, Interaction network, lcsh:TP248.13-248.65, Genetics, medicine, Oligomerization, ComputingMethodologies_COMPUTERGRAPHICS, 030304 developmental biology, 0303 health sciences, Mutation, Sigma-1 receptor, Endoplasmic reticulum membrane, medicine.diagnostic_test, Molecular dynamics simulations, Amyotrophic lateral sclerosis, Computer Science Applications, Transmembrane domain, chemistry, 030220 oncology & carcinogenesis, Sigma 1 receptor, Research Article, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::473f90f981260c9e6e57698f592744b6
https://doi.org/10.1016/j.csbj.2019.12.012

المؤلفون: Per Plenge, Ara M. Abramyan, Gunnar Sørensen, Arne Mørk, Pia Weikop, Ulrik Gether, Benny Bang-Andersen, Lei Shi, Claus J. Loland

المصدر: Nature, Nature Communications. 11(1):1-12

الإتاحة: https://ideas.repec.org/a/nat/natcom/v11y2020i1d10.1038_s41467-020-15292-y.html

المؤلفون: Jordi Bonaventura, Mark A. G. Eldridge, Feng Hu, Juan L. Gomez, Marta Sanchez-Soto, Ara M. Abramyan, Sherry Lam, Matthew A. Boehm, Christina Ruiz, Mitchell R. Farrell, Andrea Moreno, Islam

المصدر: Nature, Nature Communications. 10(1):1-12

الإتاحة: https://ideas.repec.org/a/nat/natcom/v10y2019i1d10.1038_s41467-019-12236-z.html

المؤلفون: Ara M. Abramyan, Lei Shi, Claus J. Loland, Ulrik Gether, Arne Mørk, Benny Bang-Andersen, Per Plenge, Gunnar Sørensen, Pia Weikop

المصدر: Nature Communications
Nature Communications, Vol 11, Iss 1, Pp 1-12 (2020)
Plenge, P, Abramyan, A M, Sørensen, G, Mork, A, Weikop, P, Gether, U, Bang-Andersen, B, Shi, L & Loland, C J 2020, ' The mechanism of a high-affinity allosteric inhibitor of the serotonin transporter ', Nature Communications, vol. 11, no. 1, 1491 . https://doi.org/10.1038/s41467-020-15292-y

مصطلحات موضوعية: 0301 basic medicine, Imipramine, Serotonin, Protein Conformation, Science, Allosteric regulation, General Physics and Astronomy, Drug development, Molecular neuroscience, Citalopram, Ligands, General Biochemistry, Genetics and Molecular Biology, Article, Reuptake, 03 medical and health sciences, 0302 clinical medicine, Allosteric Regulation, medicine, Animals, Binding site, lcsh:Science, Serotonin transporter, Serotonin Plasma Membrane Transport Proteins, Multidisciplinary, biology, Chemistry, General Chemistry, Ligand (biochemistry), Antidepressive Agents, Rats, Molecular Docking Simulation, 030104 developmental biology, Genetic engineering, biology.protein, Biophysics, Mutagenesis, Site-Directed, lcsh:Q, Molecular modelling, 030217 neurology & neurosurgery, Allosteric Site, Selective Serotonin Reuptake Inhibitors, medicine.drug

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51135ede0d0432322ed2914a8c5cf861
http://europepmc.org/articles/PMC7083837

المؤلفون: Julie Sanchez, Herman D. Lim, Ravi Kumar Verma, Ara M. Abramyan, Kuo-Hao Lee, Hideaki Yano, Lei Shi, Pramisha Adhikari, Jonathan A. Javitch, J. Robert Lane, Alastair C. Keen

المصدر: eLife, Vol 9 (2020)
eLife

مصطلحات موضوعية: 0301 basic medicine, Protein Conformation, QH301-705.5, Structural Biology and Molecular Biophysics, inverse agonism, Science, Molecular Dynamics Simulation, 01 natural sciences, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Molecular dynamics, Eticlopride, Biochemistry and Chemical Biology, Dopamine receptor D2, None, Drug Discovery, Salicylamides, 0103 physical sciences, Binding site, Biology (General), Receptor, Binding Sites, 010304 chemical physics, General Immunology and Microbiology, Receptors, Dopamine D2, Chemistry, Drug discovery, General Neuroscience, Molecular biophysics, Receptors, Dopamine D3, General Medicine, Risperidone, molecular dynamics, 3. Good health, 030104 developmental biology, na+ sensitivity, Structural biology, Dopamine Agonists, Biophysics, Dopamine Antagonists, Medicine, dopamine d2 receptor, Research Article, Protein Binding

وصف الملف: PDF

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cad8b8e322c324ef2f01ce0eac02ab9a
https://nottingham-repository.worktribe.com/file/4046260/1/elife-52189-v1