المؤلفون: Zhu R; Department of Orthopedics, The First Affiliated Hospital of Anhui Medical University, Anhui Medical University, 218 Jixi Road, Hefei 230022, China; Department of Orthopedics, Hefei Orthopedics Hospital, 58 Chaohu Northern Road, Hefei 238001, China., Kang Y; Department of Orthopedics, The First Affiliated Hospital of Anhui Medical University, Anhui Medical University, 218 Jixi Road, Hefei 230022, China., Li Q; School of Basic Medical Sciences, Anhui Medical University, 81 Meishan Road, Hefei 230032, China., Peng K; Department of Orthopedics, The First Affiliated Hospital of Anhui Medical University, Anhui Medical University, 218 Jixi Road, Hefei 230022, China; The Key Laboratory of Microbiology and Parasitology of Anhui Province, Anhui Medical University, 81 Meishan Road, Hefei 230032, China., Shi X; School of Basic Medical Sciences, Anhui Medical University, 81 Meishan Road, Hefei 230032, China. Electronic address: xuanming.shi@ahmu.edu.cn., Yin Z; Department of Orthopedics, The First Affiliated Hospital of Anhui Medical University, Anhui Medical University, 218 Jixi Road, Hefei 230022, China. Electronic address: ahmu_zsyin@163.com., Xuan Y; Department of Orthopedics, The First Affiliated Hospital of Anhui Medical University, Anhui Medical University, 218 Jixi Road, Hefei 230022, China; Department of Orthopedics, The Second People's Hospital of Hefei, 246 Heping Road, Hefei 230011, China. Electronic address: xy15251620255@163.com.

المصدر: Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie [Biomed Pharmacother] 2024 Jun; Vol. 175, pp. 116734. Date of Electronic Publication: 2024 May 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 8213295 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1950-6007 (Electronic) Linking ISSN: 07533322 NLM ISO Abbreviation: Biomed Pharmacother Subsets: MEDLINE

مواضيع طبية MeSH: Ferroptosis*/drug effects , alpha-Tocopherol*/pharmacology , Spinal Cord Injuries*/drug therapy , Spinal Cord Injuries*/metabolism , Spinal Cord Injuries*/pathology , Spinal Cord Injuries*/physiopathology , Recovery of Function*/drug effects , Down-Regulation*/drug effects , Arachidonate 15-Lipoxygenase*/metabolism , Arachidonate 15-Lipoxygenase*/genetics , Rats, Sprague-Dawley*, Animals ; Rats ; Lipid Peroxidation/drug effects ; Male ; Reactive Oxygen Species/metabolism ; Arachidonate 12-Lipoxygenase/metabolism ; Arachidonate 12-Lipoxygenase/genetics ; Disease Models, Animal ; Molecular Docking Simulation

المؤلفون: Zhang W; Department of Respiratory and Critical Care Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China. Electronic address: zhangweizhen157@126.com., Huang F; Department of Respiratory and Critical Care Medicine, Nanfang Hospital, Southern Medical University, Guangzhou, 510515, China., Ding X; The First Clinical College, Guangdong Medical University, Zhanjiang 524023, China., Qin J; The First Clinical College, Guangdong Medical University, Zhanjiang 524023, China., Wang W; The Marine Biomedical Research Institute of Guangdong Zhanjiang, School of Ocean and Tropical Medicine, Guangdong Medical University, Zhanjiang, Guangdong 524023, China., Luo L; The Marine Biomedical Research Institute of Guangdong Zhanjiang, School of Ocean and Tropical Medicine, Guangdong Medical University, Zhanjiang, Guangdong 524023, China. Electronic address: luolianxiang321@gdmu.edu.cn.

المصدر: Biochimica et biophysica acta. Molecular basis of disease [Biochim Biophys Acta Mol Basis Dis] 2024 Jun; Vol. 1870 (5), pp. 167176. Date of Electronic Publication: 2024 Apr 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101731730 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-260X (Electronic) Linking ISSN: 09254439 NLM ISO Abbreviation: Biochim Biophys Acta Mol Basis Dis Subsets: MEDLINE

مواضيع طبية MeSH: Ferroptosis* , Arachidonate 15-Lipoxygenase*/metabolism , Arachidonate 15-Lipoxygenase*/genetics , Lipid Peroxidation* , Asthma*/pathology , Asthma*/metabolism , Asthma*/genetics , Epithelial Cells*/metabolism , Epithelial Cells*/pathology, Animals ; Humans ; Mice ; Disease Models, Animal ; Cell Line ; Female ; Arachidonate 12-Lipoxygenase

المؤلفون: Reisch F; Department of Biochemistry, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität Zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.; Institute for Nutritional Sciences, University of Potsdam, Arthur-Scheunert-Allee 114-116, 14558, Nuthetal, Germany.; Lipidomix GmbH, Robert-Rössle-Straße 10, 13125, Berlin, Germany., Heydeck D; Department of Biochemistry, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität Zu Berlin, Charitéplatz 1, 10117, Berlin, Germany., Schäfer M; Department of Biochemistry, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität Zu Berlin, Charitéplatz 1, 10117, Berlin, Germany.; Institute for Nutritional Sciences, University of Potsdam, Arthur-Scheunert-Allee 114-116, 14558, Nuthetal, Germany., Rothe M; Lipidomix GmbH, Robert-Rössle-Straße 10, 13125, Berlin, Germany., Yang J; Department of Biochemistry, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität Zu Berlin, Charitéplatz 1, 10117, Berlin, Germany., Stehling S; Department of Biochemistry, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität Zu Berlin, Charitéplatz 1, 10117, Berlin, Germany., Püschel GP; Institute for Nutritional Sciences, University of Potsdam, Arthur-Scheunert-Allee 114-116, 14558, Nuthetal, Germany., Kuhn H; Department of Biochemistry, Charité-Universitätsmedizin Berlin, corporate member of Freie Universität Berlin and Humboldt Universität Zu Berlin, Charitéplatz 1, 10117, Berlin, Germany. hartmut.kuehn@charite.de.

المصدر: Cellular & molecular biology letters [Cell Mol Biol Lett] 2023 Nov 29; Vol. 28 (1), pp. 97. Date of Electronic Publication: 2023 Nov 29.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 9607427 Publication Model: Electronic Cited Medium: Internet ISSN: 1689-1392 (Electronic) Linking ISSN: 14258153 NLM ISO Abbreviation: Cell Mol Biol Lett Subsets: MEDLINE

مواضيع طبية MeSH: Arachidonate 15-Lipoxygenase*/genetics , Hydrogen Peroxide*, Animals ; Female ; Humans ; Male ; Mice ; Arachidonate 12-Lipoxygenase/genetics ; Arachidonic Acid ; Mammals

المؤلفون: Kianfar S; Bahrami Children Hospital, Tehran University of Medical Sciences, Tehran, Iran., Salimi V; Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran., Jahangirifard A; Lung Transplant Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran., Mirtajani SB; Lung Transplant Research Center, National Research Institute of Tuberculosis and Lung Diseases (NRITLD), Shahid Beheshti University of Medical Sciences, Tehran, Iran., Vaezi MA; Department of Biochemistry, School of Medicine, Iran University of Medical Sciences, Tehran, Iran., Yavarian J; Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran; Research Center for Antibiotic Stewardship & Antimicrobial Resistance, Tehran university of Medical Sciences, Tehran, Iran., Mokhtari-Azad T; Department of Virology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran., Tavakoli-Yaraki M; Department of Biochemistry, School of Medicine, Iran University of Medical Sciences, Tehran, Iran. Electronic address: tavakoli.m@iums.ac.ir.

المصدر: Prostaglandins, leukotrienes, and essential fatty acids [Prostaglandins Leukot Essent Fatty Acids] 2023 Oct; Vol. 197, pp. 102587. Date of Electronic Publication: 2023 Sep 03.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Churchill Livingstone Country of Publication: Scotland NLM ID: 8802730 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1532-2823 (Electronic) Linking ISSN: 09523278 NLM ISO Abbreviation: Prostaglandins Leukot Essent Fatty Acids Subsets: MEDLINE

مواضيع طبية MeSH: Arachidonate 15-Lipoxygenase*/genetics , COVID-19*, Humans ; Male ; Female ; Cyclooxygenase 2/genetics ; Cyclooxygenase 2/metabolism ; Dinoprostone/metabolism ; SARS-CoV-2/metabolism ; Cyclooxygenase 1/genetics ; Protein Isoforms ; Scavenger Receptors, Class E ; Arachidonate 5-Lipoxygenase/metabolism

المؤلفون: Makullah M; Department of Microbiology and Immunology, Tulane University, New Orleans, Louisiana, United States., Ellis DA; Department of Microbiology and Immunology, Tulane University, New Orleans, Louisiana, United States., Jones M; Department of Microbiology and Immunology, Tulane University, New Orleans, Louisiana, United States., Steele C; Department of Microbiology and Immunology, Tulane University, New Orleans, Louisiana, United States.

المصدر: American journal of physiology. Lung cellular and molecular physiology [Am J Physiol Lung Cell Mol Physiol] 2023 Aug 01; Vol. 325 (2), pp. L104-L113. Date of Electronic Publication: 2023 May 30.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Physiological Society Country of Publication: United States NLM ID: 100901229 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1504 (Electronic) Linking ISSN: 10400605 NLM ISO Abbreviation: Am J Physiol Lung Cell Mol Physiol Subsets: MEDLINE

مواضيع طبية MeSH: Arachidonate 5-Lipoxygenase*/genetics , Asthma*/metabolism, Animals ; Humans ; Mice ; Arachidonate 15-Lipoxygenase/genetics ; Arachidonate 15-Lipoxygenase/metabolism ; Arachidonic Acid ; Disease Models, Animal ; Mice, Inbred C57BL ; Mice, Knockout

المؤلفون: Damico MV; Department of Pharmacology, Paulista School of Medicine, Federal University of Sao Paulo (UNIFESP), Sao Paulo, Brazil., Gil CD; Department of Morphology and Genetics, Paulista School of Medicine, Federal University of Sao Paulo (UNIFESP), Sao Paulo, Brazil., Godinho RO; Department of Pharmacology, Paulista School of Medicine, Federal University of Sao Paulo (UNIFESP), Sao Paulo, Brazil., Pacini ESA; Department of Pharmacology, Paulista School of Medicine, Federal University of Sao Paulo (UNIFESP), Sao Paulo, Brazil., Fortes-Dias CL; Research and Development Board, Ezequiel Dias Foundation (FUNED), Belo Horizonte, Brazil., Moreira V; Department of Pharmacology, Paulista School of Medicine, Federal University of Sao Paulo (UNIFESP), Sao Paulo, Brazil. Electronic address: vmoreira@unifesp.br.

المصدر: Chemico-biological interactions [Chem Biol Interact] 2023 Jul 01; Vol. 379, pp. 110513. Date of Electronic Publication: 2023 Apr 26.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Ireland NLM ID: 0227276 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-7786 (Electronic) Linking ISSN: 00092797 NLM ISO Abbreviation: Chem Biol Interact Subsets: MEDLINE

مواضيع طبية MeSH: Arachidonate 12-Lipoxygenase*/pharmacology , Muscular Diseases*, Mice ; Animals ; Arachidonate 5-Lipoxygenase/pharmacology ; Muscle Fibers, Skeletal ; Muscle, Skeletal

المؤلفون: Kakularam KR; Department of Biochemistry, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, D-10117 Berlin, Germany., Canyelles-Niño M; Departament de Química, Universitat Autònoma de Barcelona, 08193 Barcelona, Spain.; Arquebio S.L., 08005 Barcelona, Spain., Chen X; Department of Biochemistry, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, D-10117 Berlin, Germany., Lluch JM; Departament de Química, Universitat Autònoma de Barcelona, 08193 Barcelona, Spain.; Institut de Biotecnologia i de Biomedicina (IBB), Universitat Autònoma de Barcelona, 08193 Barcelona, Spain., González-Lafont À; Departament de Química, Universitat Autònoma de Barcelona, 08193 Barcelona, Spain.; Institut de Biotecnologia i de Biomedicina (IBB), Universitat Autònoma de Barcelona, 08193 Barcelona, Spain., Kuhn H; Department of Biochemistry, Charité-Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt Universität zu Berlin, D-10117 Berlin, Germany.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2023 Jun 12; Vol. 24 (12). Date of Electronic Publication: 2023 Jun 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Arachidonate Lipoxygenases*/metabolism , Eicosapentaenoic Acid*/metabolism, Humans ; Animals ; Mice ; Docosahexaenoic Acids ; Arachidonic Acid/metabolism ; Fatty Acids ; Substrate Specificity ; Arachidonate 15-Lipoxygenase/metabolism

المؤلفون: Cai W; Tianjin Key Laboratory of Metabolic Diseases, Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Center for Cardiovascular Diseases, Research Center of Basic Medical Sciences, Department of Physiology and Pathophysiology, Tianjin Medical University, China (W.C., L.L., X.S., Y.L., J.W., Z.C., D.A., Y.Z., X.X.)., Liu L; Tianjin Key Laboratory of Metabolic Diseases, Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Center for Cardiovascular Diseases, Research Center of Basic Medical Sciences, Department of Physiology and Pathophysiology, Tianjin Medical University, China (W.C., L.L., X.S., Y.L., J.W., Z.C., D.A., Y.Z., X.X.)., Shi X; Tianjin Key Laboratory of Metabolic Diseases, Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Center for Cardiovascular Diseases, Research Center of Basic Medical Sciences, Department of Physiology and Pathophysiology, Tianjin Medical University, China (W.C., L.L., X.S., Y.L., J.W., Z.C., D.A., Y.Z., X.X.)., Liu Y; Tianjin Key Laboratory of Metabolic Diseases, Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Center for Cardiovascular Diseases, Research Center of Basic Medical Sciences, Department of Physiology and Pathophysiology, Tianjin Medical University, China (W.C., L.L., X.S., Y.L., J.W., Z.C., D.A., Y.Z., X.X.)., Wang J; Tianjin Key Laboratory of Metabolic Diseases, Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Center for Cardiovascular Diseases, Research Center of Basic Medical Sciences, Department of Physiology and Pathophysiology, Tianjin Medical University, China (W.C., L.L., X.S., Y.L., J.W., Z.C., D.A., Y.Z., X.X.)., Fang X; Third Department of Breast Cancer, Tianjin Medical University Cancer Institute and Hospital, National Clinical Research Center for Cancer, China (X.F.)., Chen Z; Tianjin Key Laboratory of Metabolic Diseases, Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Center for Cardiovascular Diseases, Research Center of Basic Medical Sciences, Department of Physiology and Pathophysiology, Tianjin Medical University, China (W.C., L.L., X.S., Y.L., J.W., Z.C., D.A., Y.Z., X.X.)., Ai D; Tianjin Key Laboratory of Metabolic Diseases, Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Center for Cardiovascular Diseases, Research Center of Basic Medical Sciences, Department of Physiology and Pathophysiology, Tianjin Medical University, China (W.C., L.L., X.S., Y.L., J.W., Z.C., D.A., Y.Z., X.X.)., Zhu Y; Tianjin Key Laboratory of Metabolic Diseases, Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Center for Cardiovascular Diseases, Research Center of Basic Medical Sciences, Department of Physiology and Pathophysiology, Tianjin Medical University, China (W.C., L.L., X.S., Y.L., J.W., Z.C., D.A., Y.Z., X.X.)., Zhang X; Tianjin Key Laboratory of Metabolic Diseases, Province and Ministry Co-sponsored Collaborative Innovation Center for Medical Epigenetics, Center for Cardiovascular Diseases, Research Center of Basic Medical Sciences, Department of Physiology and Pathophysiology, Tianjin Medical University, China (W.C., L.L., X.S., Y.L., J.W., Z.C., D.A., Y.Z., X.X.).

المصدر: Circulation [Circulation] 2023 May 09; Vol. 147 (19), pp. 1444-1460. Date of Electronic Publication: 2023 Mar 29.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0147763 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1524-4539 (Electronic) Linking ISSN: 00097322 NLM ISO Abbreviation: Circulation Subsets: MEDLINE

مواضيع طبية MeSH: Arachidonate 15-Lipoxygenase*/genetics , Arachidonate 15-Lipoxygenase*/metabolism , Arachidonate 15-Lipoxygenase*/pharmacology , Ferroptosis* , Myocardial Reperfusion Injury*/genetics , Myocardial Reperfusion Injury*/metabolism, Animals ; Mice ; Apoptosis ; Arachidonate 12-Lipoxygenase/metabolism ; Arachidonate 12-Lipoxygenase/pharmacology ; Myocytes, Cardiac/metabolism ; Necrosis/metabolism ; Peroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alpha/metabolism ; Ubiquitins/metabolism ; Ubiquitins/pharmacology

المؤلفون: Benatzy Y; Faculty of Medicine, Institute of Biochemistry I, Goethe University Frankfurt, Frankfurt, Germany., Palmer MA; Faculty of Medicine, Institute of Biochemistry I, Goethe University Frankfurt, Frankfurt, Germany., Lütjohann D; Institute for Clinical Chemistry and Clinical Pharmacology, University of Bonn, Bonn, Germany., Ohno RI; Chair of Food Chemistry, Faculty of Mathematics and Natural Sciences, University of Wuppertal, Wuppertal, Germany., Kampschulte N; Chair of Food Chemistry, Faculty of Mathematics and Natural Sciences, University of Wuppertal, Wuppertal, Germany., Schebb NH; Chair of Food Chemistry, Faculty of Mathematics and Natural Sciences, University of Wuppertal, Wuppertal, Germany., Fuhrmann DC; Faculty of Medicine, Institute of Biochemistry I, Goethe University Frankfurt, Frankfurt, Germany. Electronic address: fuhrmann@biochem.uni-frankfurt.de., Snodgrass RG; Faculty of Medicine, Institute of Biochemistry I, Goethe University Frankfurt, Frankfurt, Germany; Western Human Nutrition Research Center, Agricultural Research Service, United States Department of Agriculture, Davis, CA, USA. Electronic address: ryan.snodgrass@usda.gov., Brüne B; Faculty of Medicine, Institute of Biochemistry I, Goethe University Frankfurt, Frankfurt, Germany; Fraunhofer Institute for Translational Medicine and Pharmacology ITMP, Frankfurt, Germany; German Cancer Consortium (DKTK), Partner Site Frankfurt, Germany. Electronic address: b.bruene@biochem.uni-frankfurt.de.

المصدر: Redox biology [Redox Biol] 2024 Jun; Vol. 72, pp. 103149. Date of Electronic Publication: 2024 Apr 03.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier, B.V Country of Publication: Netherlands NLM ID: 101605639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2317 (Electronic) Linking ISSN: 22132317 NLM ISO Abbreviation: Redox Biol Subsets: MEDLINE

مواضيع طبية MeSH: Sterol Regulatory Element Binding Protein 2*/metabolism , Sterol Regulatory Element Binding Protein 2*/genetics , Lipid Peroxidation* , Cholesterol*/metabolism , Macrophages*/metabolism , Arachidonate 15-Lipoxygenase*/metabolism , Arachidonate 15-Lipoxygenase*/genetics , Homeostasis*, Humans ; MAP Kinase Signaling System ; Mitogen-Activated Protein Kinase 3/metabolism ; Mitogen-Activated Protein Kinase 3/genetics ; Mitogen-Activated Protein Kinase 1/metabolism ; Mitogen-Activated Protein Kinase 1/genetics ; Gene Expression Regulation

المؤلفون: Horio Y; Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Ikeda, Osaka, Japan; Department of Food Sciences and Nutrition, Mukogawa Women's University, Nishinomiya, Hyogo, Japan., Isegawa Y; Department of Food Sciences and Nutrition, Mukogawa Women's University, Nishinomiya, Hyogo, Japan. Electronic address: isegawa@mukogawa-u.ac.jp., Shichiri M; Biomedical Research Institute, National Institute of Advanced Industrial Science and Technology (AIST), Ikeda, Osaka, Japan. Electronic address: mototada-shichiri@aist.go.jp.

المصدر: The Journal of nutritional biochemistry [J Nutr Biochem] 2023 Apr; Vol. 114, pp. 109276. Date of Electronic Publication: 2023 Jan 20.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Country of Publication: United States NLM ID: 9010081 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-4847 (Electronic) Linking ISSN: 09552863 NLM ISO Abbreviation: J Nutr Biochem Subsets: MEDLINE

مواضيع طبية MeSH: Arachidonate 5-Lipoxygenase*/drug effects , Arachidonate 5-Lipoxygenase*/metabolism , Isoflavones*/pharmacology , MAP Kinase Signaling System*/drug effects, Humans ; Adenosine Triphosphate/metabolism ; Arachidonate 12-Lipoxygenase/metabolism ; Arachidonic Acid/metabolism ; Mitogen-Activated Protein Kinase Kinases/metabolism ; Influenza, Human/metabolism