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المؤلفون: Jinquan Cai, Ruijia Wang, Lin Lin, Hengyuan Pang, Magafurov Dinislam, Ziwei Li, Shihong Zhao, Qun Chen, Chuanlu Jiang, Pengfei Wu, Caijun Zha, Chunbin Duan, Xiangqi Meng, Bo Han
المصدر: EBioMedicine
مصطلحات موضوعية: Research paper, DNA Repair, Cellular differentiation, medicine.medical_treatment, ATRX, alpha thalassemia/mental retardation syndrome X-linked, SAA1, serum amyloid A1, Transcriptome, Mice, 0302 clinical medicine, GSEA, gene set enrichment analysis, GME, glioma microenvironment, MEM, Minimum Essential Media, BER, base excision repair, Midkine, TNFSF4, TNF superfamily member 4, NADP, nicotinamide adenine dinucleotide phosphate, General Medicine, DSBR, DNA double-strand break repair, 030220 oncology & carcinogenesis, NHEJ, nonhomologous end joining, Microglia, IHC, immunohistochemistry, γH2AX, phosphorylated on serine 139 on H2A histone family member X, CNV, copy number variation, IL6, interleukin 6, ATM, ataxia telangiectasia-mutated gene, IGV, Integrative Genomics Viewer, MDK, midkine, KEGG, Kyoto Encyclopedia of Genes and Genomes, PI, protease inhibitor, DDR, DNA damage response, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Mrc1, mannose receptor C-type 1, NER, nucleotide excision repair, Glioma, Humans, PTEN, IF, immunofluorescence, GCM, glioma-conditioned medium, IDH, isocitrate dehydrogenase (NADP(+)), Tumor microenvironment, SSBR, DNA single-strand break repair, TMZ, temozolomide, Macrophages, medicine.disease, Mice, Inbred C57BL, body regions, 030104 developmental biology, Pen/Strep, penicillin/streptomycin, HR, homologous recombination, DAPI, 4′,6-diamidino-2-phenylindole, p53, 0301 basic medicine, ATR, Ataxia Telangiectasia And Rad3-Related Protein, qRT-PCR, Quantitative real-time reverse transcription-polymerase chain reaction, DAB, Diaminobenzidine, ChIP, Chromatin immunoprecipitation, Tumor Microenvironment, DNA damage repair, FA, Fanconi anemia, MGMT, O6-methylguanine-DNA methyltransferase, biology, LGG, lower grade glioma, TLS, trans-lesion synthesis, TP53, tumor protein P53, HRP, horseradish peroxidase, Cell Differentiation, Fizz1, found in inflammatory zone 1, SNP, single nucleotide polymorphism, TCGA, The Cancer Genome Atlas dataset, Cytokine, TNFA, tumor necrosis factor alpha, Female, Arg1, arginase 1, DNA repair, SWI/SNF, SWItch/Sucrose Non-Fermentable, MMR, mismatch repair, DMEM, Dulbecco's Modified Eagle Medium, AKT, protein kinase B, CCL2, C-C motif chemokine ligand 2, CGGA, The Chinese Glioma Genome Atlas dataset, C5, Complement C5, Cell Line, Glioma microenvironment, VEGFA, vascular endothelial growth factor A, FBS, fetal bovine serum, PBS, phosphate buffered saline, Cell Line, Tumor, medicine, Animals, ELISA, Enzyme-Linked Immunosorbent Assay, DR, direct repair, GO, gene ontology, ssGSEA, single sample gene set enrichment analysis, FC, fold change, PTEN, phosphatase and tensin homolog, EGFR, epidermal growth factor receptor, TBST, Tris-buffered Saline with Tween 20, NFκB, nuclear factor kappa B, biology.protein, Cancer research, GBM, glioblastoma, EM/PM classification, EGFR module / PDGFRA (platelet derived growth factor receptor A) -based molecular classification, Tumor Suppressor Protein p53
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المؤلفون: Matthias Nahrendorf
المصدر: Journal of the American College of Cardiology
مصطلحات موضوعية: lymphocytes, PcAT, peri-cardial adipose tissue, innate lymphoid cells, Ischemia, heart failure, Inflammation, LAD, left anterior descending, medicine, Humans, Myocardial infarction, Original Investigation, business.industry, Innate lymphoid cell, Myocardial inflammation, medicine.disease, Arg1, Arginase 1, Immunity, Innate, cytokines, IL, interleukin, Treg, regulatory T cells, Myocarditis, myocardial infarction, ILC2, type 2 innate lymphoid cells, Immunology, MI, myocardial infarction, interleukin-2, ACS, acute coronary syndrome, RNAseq, RNA sequencing, medicine.symptom, Cardiology and Cardiovascular Medicine, business
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المؤلفون: Annalisa Addante, Laura M. Laiglesia, Inés Barahona, Ángela M. Valverde, Virginia Pardo, Laura Ruiz, M. Pilar Valdecantos, Aránzazu Sánchez, Patricia Rada, Águeda González-Rodríguez, Carmelo García-Monzón, María J. Moreno-Aliaga, Esther Rey
المساهمون: Nafarroako Gobernua, European Foundation for the Study of Diabetes, European Commission, Instituto de Salud Carlos III, Ministerio de Economía y Competitividad (España)
المصدر: Molecular Metabolism, Vol 7, Iss, Pp 132-146 (2018)
Repositorio Institucional de la Consejería de Sanidad de la Comunidad de Madrid
Consejería de Sanidad de la Comunidad de Madrid
Molecular Metabolism
Digital.CSIC. Repositorio Institucional del CSIC
instnameمصطلحات موضوعية: Male, 0301 basic medicine, FGF21, Steatosis, IL6, Interleukin 6, medicine.medical_treatment, Interleukin-1beta, Fgf21, fibroblast growth factor 21, Choline, Mice, Methionine, Non-alcoholic Fatty Liver Disease, Cytotoxic T cell, Cells, Cultured, Steatohepatitis, Protein Tyrosine Phosphatase, Non-Receptor Type 1, Cd36, fatty acid translocase, Fatty liver, Epithelial Cell Adhesion Molecule, mRNA, messenger RNA, 3. Good health, TNFα, tumor necrosis factor α, Cytokine, Liver, Original Article, Arg1, arginase 1, medicine.symptom, hormones, hormone substitutes, and hormone antagonists, medicine.medical_specialty, lcsh:Internal medicine, IL13, Interleukin 13, Inflammation, Biology, Oval cells, digestive system, 03 medical and health sciences, Internal medicine, medicine, Animals, Humans, lcsh:RC31-1245, Molecular Biology, No2, inducible nitric oxide synthase, Keratin-19, IL4, Interleukin 4, IL1β, Interleukin 1β, Interleukin-6, Macrophages, Insulin, PTP1B, nutritional and metabolic diseases, Cell Biology, medicine.disease, digestive system diseases, Ccl2, chemokine (C–C motif) ligand 2, Diet, Fibroblast Growth Factors, Mice, Inbred C57BL, 030104 developmental biology, Endocrinology, Immunology
وصف الملف: application/pdf
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المؤلفون: Matthew R. Gangl, Ryan K. Alexander, Prerna Bhargava, Yae-Huei Liou, Lingling Dai, Chih-Hao Lee, Sihao Liu, Nelson H. Knudsen, Alexander L. Hyde, Kristopher J. Stanya, David Jacobi
المصدر: Molecular Metabolism
Molecular Metabolism, Vol 6, Iss 10, Pp 1186-1197 (2017)مصطلحات موضوعية: 0301 basic medicine, Lipopolysaccharides, Male, ATM, adipose tissue resident macrophage, Meta-inflammation, Peroxisome proliferator-activated receptor, Adipose tissue, Apoptosis, White adipose tissue, Mice, ANGPTL4, Homeostasis, SVF, stromal vascular fraction, OCR, oxygen consumption rate, PPAR delta, chemistry.chemical_classification, M2, alternative activation of macrophage, Cell Death, Mgl1, macrophage galactose-type lectin-1, Inflammasome, WAT, white adipose tissue, Alternative activation, Plin2, perilipin 2, Cell biology, H2-Eb1, histocompatibility 2, class II antigen E beta, Bcl2, B-cell lymphoma 2, Lipotoxicity, Original Article, medicine.symptom, Arg1, arginase 1, ILC2, type 2 innate lymphoid cell, medicine.drug, BMDM, bone marrow derived macrophage, Signal Transduction, lcsh:Internal medicine, medicine.medical_specialty, M1, classic activation of macrophage, Angptl4, angiopoietin-like 4, Adipose tissue macrophages, Adipose Tissue, White, Lipolysis, Inflammation, Biology, 03 medical and health sciences, PA, palmitic acid, Nlrp3, NLR family pyrin domain containing 3, Internal medicine, medicine, Ppar, peroxisome proliferator-activated receptor, Animals, Obesity, lcsh:RC31-1245, Mogat1, monoacylglycerol O-acyltransferase 1, Molecular Biology, Sgms1, sphingomyelin synthase 1, Acadvl, acyl-CoA dehydrogenase, very long chain, Macrophages, Cell Biology, Macrophage Activation, Lipid Metabolism, Mice, Inbred C57BL, PPAR gamma, Adipose tissue macrophage, 030104 developmental biology, Endocrinology, chemistry, Stat6, signal transducer and activator of transcription 6, Slc25a20, solute carrier family 25 member 20, Interleukin-4, STAT6 Transcription Factor, Transcriptome
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المؤلفون: Jayne Louise Wilson, Roberto Motterlini, Lucie Muchová, Thierry Martens, Aniket Nikam, Anthony Ollivier, Sylvie Manin, Roberta Foresti, Sabrina Djouadi, Michael Rivard
المساهمون: Institut de Chimie et des Matériaux Paris-Est (ICMPE), Institut de Chimie du CNRS (INC)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Centre National de la Recherche Scientifique (CNRS)
المصدر: Redox Biology
Redox Biology, Elsevier, 2019, 20, pp.334-348. ⟨10.1016/j.redox.2018.10.020⟩
Redox Biology, Vol 20, Iss, Pp 334-348 (2019)مصطلحات موضوعية: Lipopolysaccharides, Male, 0301 basic medicine, Lipopolysaccharide, NQO1, NAD(P)H:quinone oxidoreductase 1, Clinical Biochemistry, Anti-Inflammatory Agents, Gene Expression, AST, aspartate aminotransferase, Pharmacology, medicine.disease_cause, Nrf2, nuclear factor erythroid 2-related factor 2, TNF-α, tumor necrosis factor-α, Biochemistry, Antioxidants, Dual-activity molecules, Mice, chemistry.chemical_compound, ARG1, arginase 1, CO-RMs, CO-releasing molecules, 0302 clinical medicine, LC-MS/MS, liquid chromatography-tandem mass spectrometry, EPF, ethyl prop-2-yn-1-yl fumarate, IL-6, interleukin-6, lcsh:QH301-705.5, Cells, Cultured, ComputingMilieux_MISCELLANEOUS, Mice, Knockout, lcsh:R5-920, M2, anti-inflammatory macrophages, Carbon Monoxide, LDH, lactate dehydrogenase, Dimethyl fumarate, IL-10, interleukin-10, [SDV.SP]Life Sciences [q-bio]/Pharmaceutical sciences, HMOX1, heme oxygenase-1 gene, 3. Good health, Nrf2 activators, CO, carbon monoxide, iNOS, inducible nitric oxide synthase, LPS, lipopolysaccharide, Cytokines, Microglia, Inflammation Mediators, medicine.symptom, lcsh:Medicine (General), Research Paper, M1, pro-inflammatory macrophages, IL-1β, interleukin-1β, NF-E2-Related Factor 2, GCLC, glutamate cysteine ligase C, Carbon monoxide (CO), Inflammation, HO-1, heme oxygenase-1 protein, GCLM, glutamate cysteine ligase M, 03 medical and health sciences, In vivo, ALT, alanine aminotransferase, medicine, Animals, [CHIM.COOR]Chemical Sciences/Coordination chemistry, ARG1, MCP-1/CCL2, monocyte chemoattractant protein-1, ALP, alkaline phosphatase, Macrophage phenotype, Activator (genetics), Macrophages, Organic Chemistry, In vitro, Disease Models, Animal, Oxidative Stress, 030104 developmental biology, lcsh:Biology (General), chemistry, HYCOs, HYbrid CO-releasing molecules, COHb, carbonmonoxy hemoglobin, Heme Oxygenase-1, 030217 neurology & neurosurgery, Oxidative stress, Hb, hemoglobin
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المؤلفون: Pingping Shen, WenYu, Dan Weng, Xiujing Feng, Jian-Xin Li, Dianhua Chen, Haijian Fu, Nanfei Yang, Jingfa Zhao, Yahong Huang, Jiajia Chen, Ren-Xiang Tan, Haohan Qin, Young D. Owen, Feifei Zhou
المصدر: EBioMedicine
EBioMedicine, Vol 9, Iss C, Pp 61-76 (2016)مصطلحات موضوعية: 0301 basic medicine, Male, PPARγ, EMSA, electrophoretic mobility shift assay, lcsh:Medicine, Adipose tissue, Peroxisome proliferator-activated receptor, AST, aspartate aminotransferase, Pharmacology, NF-κB, IHC, Immunological Histological Chemistry, chemistry.chemical_compound, SPF, specific-pathogen-free, Mice, HFD, high fat diet, Obesity-related inflammation, Thiazolidinedione, Apigenin, NF-κB, nuclear factor kappa B, PPARγ, peroxisome proliferator activated receptor γ, chemistry.chemical_classification, Metabolic Syndrome, lcsh:R5-920, ND, normal diet, ITC, isothermal titration calorimetry, NF-kappa B, Api, apigenin, WAT, white adipose tissue, General Medicine, TG, triglycerides, Arg1, arginase, SEM, standard error of mean, Phenotype, Biochemistry, Adipose Tissue, Macrophage polarization, Cytokines, medicine.symptom, TZD, thiazolidinedione, lcsh:Medicine (General), Rosiglitazone, ATM, adipocyte tissue macrophages, medicine.drug, Research Paper, Protein Binding, Signal Transduction, Normal diet, medicine.drug_class, Inflammation, LBD, ligand binding domain, General Biochemistry, Genetics and Molecular Biology, Cell Line, Immunophenotyping, PI, propidium iodide, 03 medical and health sciences, ROS, reactive oxygen species, AnV, Annexin V-FITC, ALT, alanine aminotransferase, medicine, Animals, Protein Interaction Domains and Motifs, Obesity, NO, nitric oxide, Rosi, rosiglitazone, Macrophages, lcsh:R, CT, computer tomography, Macrophage Activation, TC, total cholesterol, PPAR gamma, Disease Models, Animal, 030104 developmental biology, chemistry, DBD, DNA binding domain, ITTs, insulin tolerance tests, H&E, hematoxylin and eosin, Macrophages, Peritoneal, Fizz1, found in inflammatory zone (FIZZ)1, CD206, mannose receptor C type 1, Thiazolidinediones, SPPARMs, selective PPAR modulators, Biomarkers
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المؤلفون: Xiu-Fen Ming, Gautham Yepuri, Michael Forbiteh, Zhihong Yang, Jean-Pierre Montani, Yuyan Xiong, Yi Yu
المصدر: Autophagy
مصطلحات موضوعية: Baf A1, bafilomycin A1, WT, wild type, RPS6, ribosomal protein S6, senescence, AMP-Activated Protein Kinases, ARGINASE, mTORC2, ARG1, arginase 1, 0302 clinical medicine, ARG2, arginase 2, LC3, microtubule-associated protein 1 light chain 3, LDL, low-density lipoprotein, SA-ß-gal, senescence-associated-β-gal, AKT/PKB, v-akt murine thymoma viral oncogene homolog 1, ANOVA, analysis of variance, Cellular Senescence, 0303 health sciences, BECN1, Beclin 1, autophagy-related, NOS3/eNOS, nitric oxide synthase 3 (endothelial cell), MTOR, Three-MA, 3-methyladenine, nor-NOHA, Nω-hydroxy-nor-Arginine, TOR Serine-Threonine Kinases, endothelial cells, RPS6KB1/S6K1, ribosomal protein S6 kinase, 70kDa, polypeptide 1, Atg, autophagy-related, 030220 oncology & carcinogenesis, Ribosomal protein s6, shRNA, short hairpin RNA, AR, aortic roots, SMC, smooth muscle cells, HAEC, human aortic endothelial cells, PtdIns3K, phosphatidylinositol 3-kinase, Signal Transduction, VWF, von Willebrand factor, autophagy, Basic Research Papers, MTOR, mechanistic target of rapamycin, Mice, Transgenic, P70-S6 Kinase 1, Mechanistic Target of Rapamycin Complex 2, Mechanistic Target of Rapamycin Complex 1, Biology, PE, phosphatidylethanolamine, Diet, High-Fat, apoe−/−, Apolipoprotein E-deficient, TP53/p53, tumor protein 53, 03 medical and health sciences, HUVEC, human umbilical vein endothelial cells, Animals, Humans, Protein kinase A, Molecular Biology, Mechanistic target of rapamycin, SQSTM1/p62, sequestosome 1, PI3K/AKT/mTOR pathway, H160F, inactive mutant of mouse ARG2, 030304 developmental biology, PRKAA/AMPK, protein kinase, AMP-activated, α catalytic subunit, EC, endothelial cell, Autophagy, arg2−/−, arginase type II deficient, AMPK, CMV, cytomegalovirus, Cell Biology, Atherosclerosis, BEC, S-12 bromoethyl-L-cystine-HCl, ULK1, unc-51 like autophagy activating kinase 1, Multiprotein Complexes, Cancer research, biology.protein, PRKAA
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المؤلفون: Frank Tacke, Thomas Ritz
المصدر: EBioMedicine, Vol 29, Iss, Pp 7-8 (2018)
EBioMedicine 29, 7-8 (2018). doi:10.1016/j.ebiom.2018.02.004
EBioMedicineمصطلحات موضوعية: Liver Cirrhosis, DKO, double knockout, 0301 basic medicine, Macrophage, Hyp, hydroxyproline, Liver fibrosis, TGFβ1, transforming growth factor beta 1 transcript, lcsh:Medicine, CCl4, carbon tetrachloride, Medicine, TNF-α, tumor necrosis factor alpha, Janus, TIMP, tissue inhibitor of metalloproteinase 1, Mice, Knockout, Mice, Inbred BALB C, lcsh:R5-920, Progression, BW, body weight, MMP12, PDGF, platelet-derived growth factor beta, General Medicine, MRC1, mannose receptor C type 1 (CD206), Arg1, Arginase 1, HSC, hepatic stellate cell, ECM, extracellular matrix, MMP, matrix metalloproteinase, Reversal, IFNγ, interferon-gamma, CCL2, chemokine (C-C motif) ligand 2, Liver, iNOS, inducible nitric oxide synthase, qPCR, quantitative polymerase chain reaction, lcsh:Medicine (General), Research Paper, DAPI, 4,6-diamidino-2-phenylindole, ASO, antisense oligonucleotide, SEM, standard error of the mean, Gapdh, glyceraldehyde 3-phosphate dehydrogenase, General Biochemistry, Genetics and Molecular Biology, 03 medical and health sciences, Text mining, Humans, WT, wildtype, Col1a1, procollagen α1(I) transcript, IL-4 receptor alpha, business.industry, Macrophages, lcsh:R, Macrophage Activation, Fibrosis, 030104 developmental biology, STAT3/STAT6, signal transducer and activator of transcription 3 or 6, α-SMA, alpha–smooth muscle actin, Immunology, IL-4Rα, interleukin-4 receptor alpha, business
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9دورية أكاديمية
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المؤلفون: Toni, Weinhage, Jan, Däbritz, Anne, Brockhausen, Timo, Wirth, Markus, Brückner, Michael, Belz, Dirk, Foell, Georg, Varga
المصدر: Cellular and Molecular Gastroenterology and Hepatology
مصطلحات موضوعية: WT, wild type, ATP, adenosine triphosphate, T Cell, IL-1Ra, IL-1 receptor antagonist, Experimental Colitis, PBS, phosphate-buffered saline, Adaptive Immunity, Monocyte, CD73, ecto-5′-nucleotidase, PCR, polymerase chain reaction, ROS, reactive oxygen species, DC, dendritic cells, DSS, dextran sulfate sodium, GM-CSF, granulocyte macrophage colony-stimulating factor, CD, Crohn’s disease, RA, retinoic acid, Dextran Sulfate Sodium, CD39, E-NTPDase, Immune Response, Original Research, NO, nitric oxide, IBD, inflammatory bowel disease, GM-CSF, CFSE, carboxyfluorescein succinimidyl ester, Innate Immunity, qRT-PCR, quantitative reverse-transcription polymerase chain reaction, Foxp3, forkhead-box-protein P3, IL, interleukin, Treg, regulatory T cells, TNFα, tumor necrosis factor α, OD, optical density, ALDH, aldehyde dehydrogenase, MACS, magnetic-activated cell sorting, LPS, lipopolysaccharide, MEICS, murine endoscopic index of colitis severity, FCS, fetal calf serum, GMaM, granulocyte-macrophage colony-stimulating factor–activated monocytes, Arg1, arginase 1
URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::59b8c900c87291c0ebcd84642e07ae37
https://pubmed.ncbi.nlm.nih.gov/28210690
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