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1دورية أكاديمية
المؤلفون: Patrick Baum, Ramona Schmid, Carina Ittrich, Werner Rust, Katrin Fundel-Clemens, Susanne Siewert, Martin Baur, Lisa Mara, Lore Gruenbaum, Armin Heckel, Roland Eils, Roland E Kontermann, Gerald J Roth, Florian Gantner, Andreas Schnapp, John E Park, Andreas Weith, Karsten Quast, Detlev Mennerich
المصدر: PLoS ONE, Vol 5, Iss 12, p e14272 (2010)
وصف الملف: electronic resource
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المؤلفون: Wolfgang J. Rettig, Armin Heckel, Jens Quant, Andreas Zoephel, Gerd Bader, Pilar Garin-Chesa, Ulrike Tontsch-Grunt, Wolfgang Sommergruber, Susanna Kautschitsch, Martin Krssak, Gerald J. Roth, Frank Hilberg
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::15b6ea2186679c686773cc82eb8804b8
https://doi.org/10.1158/0008-5472.c.6497339 -
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المؤلفون: Wolfgang J. Rettig, Armin Heckel, Jens Quant, Andreas Zoephel, Gerd Bader, Pilar Garin-Chesa, Ulrike Tontsch-Grunt, Wolfgang Sommergruber, Susanna Kautschitsch, Martin Krssak, Gerald J. Roth, Frank Hilberg
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4dc987044139262ecca31c9b8b23fd85
https://doi.org/10.1158/0008-5472.22374101.v1 -
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المؤلفون: Patrick Baum, Trixi Brandl, Detlev Mennerich, Stefan Hoerer, Gisela Schnapp, Joerg Kley, Gerald Juergen Roth, Matthias Grauert, Andreas Schnapp, Armin Heckel, John Edward Park
المصدر: Journal of Medicinal Chemistry. 53:7287-7295
مصطلحات موضوعية: Models, Molecular, Indoles, Receptor, Platelet-Derived Growth Factor alpha, p38 mitogen-activated protein kinases, Receptor, Transforming Growth Factor-beta Type I, Smad2 Protein, Protein Serine-Threonine Kinases, Pharmacology, Crystallography, X-Ray, Cell Line, Structure-Activity Relationship, Growth factor receptor, Drug Discovery, Humans, Structure–activity relationship, Kinome, Smad3 Protein, Phosphorylation, Receptor, Chemistry, Stereoisomerism, Protein kinase domain, Drug Design, Molecular Medicine, Receptors, Transforming Growth Factor beta, Transforming growth factor
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المؤلفون: Thorsten Lehmann, Ralf Lotz, Thorsten Oost, Mueller Stephan Georg, Klaus Rudolf, Dirk Stenkamp, Armin Heckel, Ralph Budzinski, Jörg Kley, Gerd-Michael Maier, Gerald Juergen Roth, Leo Thomas, Martin Lenter, Kirsten Arndt, Michael Markert
المصدر: Bioorganicmedicinal chemistry letters. 25(16)
مصطلحات موضوعية: medicine.medical_specialty, Pyridines, Clinical Biochemistry, hERG, Pharmaceutical Science, Pharmacology, In Vitro Techniques, Lipidoses, Biochemistry, Part iii, Structure-Activity Relationship, Internal medicine, Appetite Depressants, Drug Discovery, medicine, Potassium Channel Blockers, Moiety, Animals, Humans, Receptors, Somatostatin, Receptor, Molecular Biology, Phospholipids, Phospholipidosis, biology, Chemistry, Organic Chemistry, Body Weight, Antagonist, Ether-A-Go-Go Potassium Channels, High-Throughput Screening Assays, Rats, Pyridazines, Endocrinology, Design synthesis, Pyrazines, biology.protein, Hepatocytes, Microsomes, Liver, Molecular Medicine, Anti-Obesity Agents, Cyclobutanes, Sibutramine, medicine.drug
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6
المؤلفون: Gerd-Michael Maier, Thorsten Lehmann, Ralf Lotz, Jörg Kley, Martin Lenter, Michael Markert, Mueller Stephan Georg, Kirsten Arndt, Philipp Lustenberger, Klaus Rudolf, Thorsten Oost, Armin Heckel, Marcus Schindler, Gerald Juergen Roth, Dirk Stenkamp
المصدر: Bioorganicmedicinal chemistry letters. 25(16)
مصطلحات موضوعية: Pyridines, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Biochemistry, Receptors, G-Protein-Coupled, Eating, Structure-Activity Relationship, Animal model, In vivo, Drug Discovery, Potency, Animals, Cytochrome P-450 Enzyme Inhibitors, ATP Binding Cassette Transporter, Subfamily B, Member 1, Obesity, Receptors, Somatostatin, Receptor, Molecular Biology, Chemistry, Organic Chemistry, Body Weight, Antagonist, Limiting, High-Throughput Screening Assays, Rats, Design synthesis, Cytochrome P-450 CYP2D6, Alkynes, Drug Design, Molecular Medicine, Efflux, Anti-Obesity Agents
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7
المؤلفون: Kirsten Arndt, Ralf Lotz, Klaus Rudolf, Thorsten Lehmann, Mueller Stephan Georg, Ralph Budzinski, Gerald Juergen Roth, Leo Thomas, Martin Lenter, Dirk Stenkamp, Armin Heckel, Thorsten Oost, Marcus Schindler, Jörg Kley
المصدر: Bioorganicmedicinal chemistry letters. 25(16)
مصطلحات موضوعية: Clinical Biochemistry, hERG, Pharmaceutical Science, Pharmacology, Lipidoses, Biochemistry, Structure-Activity Relationship, Drug Discovery, Potassium Channel Blockers, Animals, Receptor, Serotonin, 5-HT2A, Receptors, Somatostatin, Rats, Wistar, Receptor, Molecular Biology, Phospholipids, G protein-coupled receptor, Phospholipidosis, biology, Chemistry, Organic Chemistry, Ether-A-Go-Go Potassium Channels, Rats, Pyridazines, Safety profile, Design synthesis, biology.protein, Molecular Medicine, Anti-Obesity Agents, Serotonin Antagonists
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8
المؤلفون: Richard W. Cole, Silke Hauf, Jan-Michael Peters, Conly L. Rieder, Armin Heckel, Gisela Schnapp, Christine Zimmer, Rainer Walter, Sabrina LaTerra, Jacques van Meel
المصدر: The Journal of Cell Biology
مصطلحات موضوعية: Indoles, Paclitaxel, Aurora B kinase, Mitosis, Cell Cycle Proteins, Spindle Apparatus, Biology, Protein Serine-Threonine Kinases, Microtubules, Article, Kinetochore microtubule, Polyploidy, Aurora Kinases, Chromosome Segregation, Endopeptidases, Animals, Aurora Kinase B, Humans, RNA, Small Interfering, Kinetochores, Separase, Anaphase, Sulfonamides, Cohesin, Kinetochore, Nocodazole, Thiones, Cell Biology, Aneugens, Cell biology, Spindle apparatus, Genes, cdc, Spindle checkpoint, Eukaryotic Cells, Phenotype, Pyrimidines, Protein Kinases, mitosis, chromosome segregation, kinetochores, spindle assembly checkpoint, chemical biology, HeLa Cells
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bad5655f4b0e0696fbed98ac16abcf7
http://europepmc.org/articles/PMC2172906 -
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المؤلفون: Lucia Glocker, Herbert Nar, Martin Lenter, Wolfgang Rist, Adelheid Löhle, Adina Berg, Alexander Pautsch, Dirk Reinert, Armin Heckel, Nadja Stadler, Stefan Kauschke, Gisela Schnapp
المصدر: Biochemistry. 52(20)
مصطلحات موضوعية: Regulation of gene expression, Models, Molecular, Binding Sites, Glucokinase regulatory protein, Glucokinase, Protein Conformation, Fructosephosphates, Fructose, Biology, Crystallography, X-Ray, Biochemistry, Turn (biochemistry), chemistry.chemical_compound, Cytosol, chemistry, biology.protein, Glucose homeostasis, Humans, Binding site, Adaptor Proteins, Signal Transducing
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المؤلفون: Thomas Muller, Armin Heckel, Rainer Soyka, J. Nickl, Hans Weisenberger, W. Eisert
المصدر: Journal of Medicinal Chemistry. 37:26-39
مصطلحات موضوعية: Blood Platelets, Platelet Aggregation, Phosphodiesterase Inhibitors, Pyridines, medicine.drug_class, Stereochemistry, Receptors, Thromboxane, Molecular Conformation, Tritium, Structure-Activity Relationship, Thromboxane A2, chemistry.chemical_compound, Drug Discovery, medicine, Humans, Platelet, Sulfonyl, chemistry.chemical_classification, Molecular Structure, biology, Bridged Bicyclo Compounds, Heterocyclic, Receptor antagonist, Hydrazines, chemistry, Enzyme inhibitor, Drug Design, Fatty Acids, Unsaturated, biology.protein, Molecular Medicine, Collagen, Thromboxane-A Synthase, Cyclooxygenase, Thromboxane-A synthase, Platelet Aggregation Inhibitors, Prostaglandin H2
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a15994671559772ce4619a9efabe5409
https://doi.org/10.1021/jm00027a004