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1دورية أكاديمية
المؤلفون: Arna Katewa, Eric Suto, Jessica Hui, Jose Heredia, Jie Liang, Jason Hackney, Keith Anderson, Tuija M Alcantar, Natasha Bacarro, Debra Dunlap, Jeffrey Eastham, Andres Paler-Martinez, Xin Y Rairdan, Zora Modrusan, Wyne P Lee, Cary D Austin, Daniel Lafkas, Nico Ghilardi
المصدر: PLoS ONE, Vol 16, Iss 1, p e0244439 (2021)
وصف الملف: electronic resource
Relation: https://doaj.org/toc/1932-6203
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المؤلفون: Christopher McBride, Lynnie Trzoss, Davide Povero, Milos Lazic, Geza Ambrus-Aikelin, Angelina Santini, Rama Pranadinata, Gretchen Bain, Ryan Stansfield, Jeffrey A. Stafford, James Veal, Ryan Takahashi, Justin Ly, Shu Chen, Liling Liu, Marika Nespi, Robert Blake, Arna Katewa, Tracy Kleinheinz, Swathi Sujatha-Bhaskar, Nandhini Ramamoorthi, Jessica Sims, Brent McKenzie, Mark Chen, Mark Ultsch, Matthew Johnson, Jeremy Murray, Claudio Ciferri, Steven T. Staben, Michael J. Townsend, Craig E. Stivala
المصدر: Journal of Medicinal Chemistry. 65:14721-14739
مصطلحات موضوعية: Drug Discovery, Molecular Medicine
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المؤلفون: Joseph W. Lubach, Jennifer Vogt, Wendy B. Young, Charles Eigenbrot, Arna Katewa, James J. Crawford, Dinah Misner, Harvey Wong, Hans E. Purkey, Wendy Lee, Adam R. Johnson, Karin Reif, Jacob Z. Chen, Satoko Kakiuchi-Kiyota, Lichuan Liu, Julia Heidmann, Christine Yu, James R. Kiefer, Kelly J. Delatorre
المصدر: ACS Med Chem Lett
مصطلحات موضوعية: Systemic lupus erythematosus, biology, 010405 organic chemistry, Chemistry, Btk inhibitors, Organic Chemistry, hERG, medicine.disease, 01 natural sciences, Biochemistry, 0104 chemical sciences, 010404 medicinal & biomolecular chemistry, immune system diseases, hemic and lymphatic diseases, Rheumatoid arthritis, Drug Discovery, medicine, biology.protein, Cancer research, Immune Diseases, Bruton's tyrosine kinase, skin and connective tissue diseases, Tyrosine kinase
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المؤلفون: Eric Suto, Wyne P. Lee, Jessica Hui, Jie Liang, Xin Y. Rairdan, Jason A. Hackney, Debra Dunlap, Keith R. Anderson, Nico Ghilardi, Jeffrey Eastham, Cary D. Austin, Arna Katewa, Tuija M. Alcantar, Natasha Bacarro, Daniel Lafkas, Andres Paler-Martinez, Jose E. Heredia, Zora Modrusan
المصدر: PLoS ONE, Vol 16, Iss 1, p e0244439 (2021)
PLoS ONEمصطلحات موضوعية: 0301 basic medicine, B Cells, Heredity, Physiology, Biochemistry, White Blood Cells, Mice, 0302 clinical medicine, Animal Cells, immune system diseases, Immune Physiology, Medicine and Health Sciences, Lupus Erythematosus, Systemic, skin and connective tissue diseases, Immune Response, Mice, Knockout, Innate Immune System, Heterozygosity, Multidisciplinary, Systemic lupus erythematosus, Mice, Inbred NZB, Genetically Modified Organisms, Imidazoles, Animal Models, Survival Rate, medicine.anatomical_structure, Experimental Organism Systems, Engineering and Technology, Cytokines, Medicine, Cellular Types, Anatomy, Chemokines, Genetic Engineering, Research Article, Biotechnology, Immune Cells, Science, Immunology, Bioengineering, Mouse Models, Research and Analysis Methods, 03 medical and health sciences, Model Organisms, Signs and Symptoms, Immune system, Genetics, medicine, Animals, Antibody-Producing Cells, B cell, Inflammation, 030203 arthritis & rheumatology, Autoimmune disease, Blood Cells, Lupus erythematosus, Innate immune system, Genetically Modified Animals, Terpenes, business.industry, Biology and Life Sciences, Proteins, Interferon-alpha, Membrane Transport Proteins, TLR9, Kidneys, Cell Biology, Renal System, Dendritic Cells, TLR7, Molecular Development, medicine.disease, Mice, Inbred C57BL, 030104 developmental biology, Toll-Like Receptor 7, Immune System, Toll-Like Receptor 9, Animal Studies, Interferons, Clinical Medicine, business, Developmental Biology
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المؤلفون: Lucinda Tam, Annemarie Lekkerkerker, Jeffrey Eastham-Anderson, Melanie Domeyer, Brent S. McKenzie, Azadeh Hadadianpour, Eugene Varfolomeev, Arna Katewa, Steven Do, A. Francesca Setiadi, Wyne P. Lee, Joy Drobnick, Andres Paler-Martinez, Rajita Pappu, Katherine Bao, Marian C. Bryan, Alfred Wong, James J. Crawford, Cesar A. Corzo, Vida Asghari, Sha Klabunde, Vladimir Ramirez-Carrozi, Jodie Pang, Jason A. Hackney, Hans Brightbill, Christopher Dela Cruz, Ross Francis, Yonglian Sun, Merone Roose-Girma, Claire Emson, Wendy B. Young, Michael J. Townsend, James R. Kiefer, Cary D. Austin, Swathi Sujatha-Bhaskar, Emily Hunley, Nico Ghilardi, Daqi Xu, Søren Warming, Kate Senger, Zhiyu Huang, Vivian W. C. Lau, Domagoj Vucic, Ali A. Zarrin, Eric Suto
المصدر: Science signaling. 13(634)
مصطلحات موضوعية: Plasma Cells, Endosomes, Biochemistry, 03 medical and health sciences, Mice, 0302 clinical medicine, immune system diseases, Interferon, medicine, Agammaglobulinaemia Tyrosine Kinase, Bruton's tyrosine kinase, Animals, Humans, Kinase activity, Molecular Biology, IRGs, 030304 developmental biology, 0303 health sciences, Membrane Glycoproteins, biology, Chemistry, Cell Biology, Dendritic Cells, IRAK4, Immune complex, Cell biology, Interleukin-1 Receptor-Associated Kinases, Toll-Like Receptor 7, biology.protein, Signal transduction, Tyrosine kinase, 030215 immunology, medicine.drug, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6df56c99041e31c3d42be9d115b0561d
https://pubmed.ncbi.nlm.nih.gov/32487715 -
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المؤلفون: Steve Gallion, Jacob Z. Chen, Kropf Jeffrey E, Joseph W. Lubach, Pat Maciejewski, Heleen Scheerens, Seung H. Lee, Aaron C. Schmitt, Daniel F. Ortwine, Arna Katewa, Jin-Ming Xiong, Huiyong Hu, James J. Crawford, Wei Deng, Karin Reif, Zhongdong Zhao, Julie DiPaolo, Liming Dong, Kevin S. Currie, Fusheng Zhou, Peter Blomgren, Jonathon Hau, Charles Eigenbrot, Meire Bremer, Jen Macaluso, Adam R. Johnson, Scott A. Mitchell, Jianjun Xu, Lichuan Liu, James Barbosa, Wendy B. Young, Harvey Wong, Xiaojing Wang
المصدر: ACS Medicinal Chemistry Letters
مصطلحات موضوعية: 0301 basic medicine, Lupus, Arthritis, Pharmacology, Biochemistry, 03 medical and health sciences, Animal model, immune system diseases, hemic and lymphatic diseases, Drug Discovery, medicine, Bruton's tyrosine kinase, Rheumatoid arthritis, chemistry.chemical_classification, Kinase inhibitor, Systemic lupus erythematosus, G-744, biology, Organic Chemistry, medicine.disease, Featured Letter, 030104 developmental biology, chemistry, Btk, biology.protein, Tyrosine kinase, Tricyclic
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المؤلفون: Edna F. Choo, Kevin DeMent, Jodie Pang, Dimitry M. Danilenko, Dolores Diaz, Arna Katewa, Dong U. Lee, Gopinath S. Palanisamy, Nico Ghilardi, Janice Corpuz, Paula Katavolos, Charly Sioson
المصدر: Toxicology and Applied Pharmacology. 300:47-54
مصطلحات موضوعية: Epigenomics, Male, 0301 basic medicine, BRD4, Reticulocytes, Protein Serine-Threonine Kinases, Toxicology, Monocytes, Mice, 03 medical and health sciences, In vivo, Transcriptional regulation, Animals, Lymphocytes, Epigenetics, Pharmacology, Transcriptionally active chromatin, Dose-Response Relationship, Drug, biology, Azepines, Organ Size, Triazoles, Molecular biology, Bromodomain, Cell biology, Mice, Inbred C57BL, 030104 developmental biology, Histone, Immune System, biology.protein
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المؤلفون: Daniel F. Ortwine, Rebecca Erickson, Jonathan Hau, Binqing Wei, Charles Eigenbrot, Arna Katewa, James J. Crawford, Regina Choy, Dinah Misner, Georgette Castanedo, Pawan Bir Kohli, Suzanne Tay, Liming Dong, Lisa D. Belmont, Joseph W. Lubach, Wendy B. Young, Adam R. Johnson, Lichuan Liu, Harvey Wong, Leah Schutt, Karin Reif, Brent S. McKenzie, Melis Coraggio, Nico Ghilardi, Wendy Lee
المصدر: Journal of medicinal chemistry. 61(6)
مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Pyridones, Inflammatory arthritis, Anti-Inflammatory Agents, Arthritis, Piperazines, Madin Darby Canine Kidney Cells, Arthritis, Rheumatoid, Rats, Sprague-Dawley, 03 medical and health sciences, Dogs, immune system diseases, Drug Discovery, medicine, Agammaglobulinaemia Tyrosine Kinase, Bruton's tyrosine kinase, Animals, Humans, Lupus Erythematosus, Systemic, Protein Kinase Inhibitors, B cell, Systemic lupus erythematosus, Lupus erythematosus, biology, Molecular Structure, Chemistry, medicine.disease, Arthritis, Experimental, Rats, 030104 developmental biology, medicine.anatomical_structure, Rats, Inbred Lew, Rheumatoid arthritis, biology.protein, Cancer research, Molecular Medicine, Tyrosine kinase
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المؤلفون: Laura DeForge, Eric Suto, Justin Lesch, Joseph W. Lubach, Arna Katewa, Zora Modrusan, Tao Huang, Allen Nguyen, Harvey Wong, Lichuan Liu, Jianyong Wang, Jason A. Hackney, James J. Crawford, Adam R. Johnson, Chungkee Poon, Sami McVay, Jacob Z. Chen, Zhonghua Lin, Yugang Wang, Marya Liimatta, Jason DeVoss, Peter Blomgren, Kevin S. Currie, Karin Reif, Wendy B. Young, Cary D. Austin, Michael J. Townsend, Nandhini Ramamoorthi, Jonathan Hau, Julie DiPaolo, Meire Bremer, Wyne P. Lee
المصدر: JCI Insight. 2
مصطلحات موضوعية: 0301 basic medicine, Myeloid, Plasma Cells, Lupus nephritis, Gene Expression, Kidney, Lymphocyte Activation, Mice, 03 medical and health sciences, immune system diseases, Agammaglobulinaemia Tyrosine Kinase, medicine, Animals, Humans, Bruton's tyrosine kinase, Myeloid Cells, skin and connective tissue diseases, B-cell activating factor, B cell, Autoantibodies, Cell Proliferation, B-Lymphocytes, Systemic lupus erythematosus, Mice, Inbred NZB, biology, business.industry, Interferon-alpha, Glomerulonephritis, General Medicine, medicine.disease, Lupus Nephritis, Disease Models, Animal, 030104 developmental biology, medicine.anatomical_structure, Immunology, biology.protein, Female, business, Nephritis, Research Article
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f495b8b0af6744c8645b436f824312ac
https://doi.org/10.1172/jci.insight.90111 -
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المؤلفون: Arna Katewa, Daniel F. Ortwine, Pawan Bir Kohli, James J. Crawford, Christine Tam, Regina Choy, Yvonne Franke, Jiansheng Wu, Hong Li, Luciana Burton, Adam R. Johnson, Emily B. Gogol, Charles Eigenbrot, Kyle Mortara, Lisa D. Belmont, Elicia Penuel, Philippe Bergeron, Wendy B. Young, Alberto Estevez, May Lin, Christine Yu, Krista K. Bowman
المصدر: ACS chemical biology. 11(10)
مصطلحات موضوعية: 0301 basic medicine, Threonine, Mutant, Antineoplastic Agents, medicine.disease_cause, Biochemistry, 03 medical and health sciences, chemistry.chemical_compound, 0302 clinical medicine, Piperidines, immune system diseases, hemic and lymphatic diseases, medicine, Agammaglobulinaemia Tyrosine Kinase, Bruton's tyrosine kinase, Humans, Cysteine, Binding site, Protein Kinase Inhibitors, chemistry.chemical_classification, Mutation, biology, Adenine, General Medicine, Protein-Tyrosine Kinases, Leukemia, Lymphocytic, Chronic, B-Cell, Kinetics, 030104 developmental biology, Enzyme, Pyrimidines, chemistry, 030220 oncology & carcinogenesis, Ibrutinib, biology.protein, Cancer research, Molecular Medicine, Pyrazoles, Signal transduction, Tyrosine kinase