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المؤلفون: Kevin N. Winzenberg, Teresa Cablewski, Abdelselam Ali, Roger M. Sargent, David G. Sawutz, Ashit K. Ganguly, Craig L. Francis
المصدر: Bioorganic & Medicinal Chemistry Letters. 21:4160-4163
مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Chemical synthesis, Pyridazine, Structure-Activity Relationship, chemistry.chemical_compound, Ivermectin, Drug Discovery, medicine, Animals, Anthelmintic, Molecular Biology, biology, Bicyclic molecule, Antinematodal Agents, Organic Chemistry, biology.organism_classification, In vitro, Pyridazines, chemistry, Larva, Benzene derivatives, Molecular Medicine, Haemonchus, Haemonchus contortus, medicine.drug
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المؤلفون: Urooj A. Mirza, Doll Ronald J, Birendra N. Pramanik, Viyyoor M. Girijavallabhan, Guodong Chen, Yan-Hui Liu, Ashit K. Ganguly
المصدر: Journal of Mass Spectrometry. 43:1393-1401
مصطلحات موضوعية: chemistry.chemical_classification, Protein Denaturation, Spectrometry, Mass, Electrospray Ionization, Electrospray, Alkyl and Aryl Transferases, Farnesyl Protein Transferase, Pyridines, Stereochemistry, Pentamer, Electrospray ionization, Size-exclusion chromatography, Farnesyl pyrophosphate, Mass spectrometry, Mass Spectrometry, Molecular Weight, chemistry.chemical_compound, Enzyme, Piperidines, chemistry, Chromatography, Gel, lipids (amino acids, peptides, and proteins), Enzyme Inhibitors, Spectroscopy
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المؤلفون: Weidong Pan, Prudence Bradley, Kevin X. Chen, Parekh Tejal N, Andrea Hart, Frank Bennett, Danial Prelusky, Srikanth Venkatraman, Robert Chase, Susan Bogdanowich-Knipp, Jianshe Kong, Bancha Vibulbhan, Viyyoor M. Girijavallabhan, Hendrata Siska, Rong Kong, Weiying Yang, Kuo-Chi Cheng, Ashit K. Ganguly, Nancy Butkiewicz, Ashok Arasappan, Yuhua Huang, Andrew Prongay, Bruce A. Malcolm, Xiang Liang, Rong Liu, Xiaoming Cui, Walter A. Korfmacher, Sony Agrawal, Wanli Wu, Zhuyan Guo, Stephane L. Bogen, Pike Russell E, Ronald E. White, Jesse Wong, Yi-Tsung Liu, Jean-Marc Brisson, John Pichardo, Anil K. Saksena, Pavlovsky Anastasia, Bahige M. Baroudy, F. George Njoroge, Vincent Madison, Patrick Pinto, Santhanam Bama, Raymond G. Lovey, Edwin Jao, Lisa Broske, Veljko Popov, Yunsheng Hsieh, Paul Ingravallo, Sumei Ruan, Piwinski John J
المصدر: Journal of Medicinal Chemistry. 49:6074-6086
مصطلحات موضوعية: Hepatitis, NS3, biology, Hepacivirus, Hepatitis C virus, Ribavirin, Hepatitis C, medicine.disease, biology.organism_classification, medicine.disease_cause, Virology, chemistry.chemical_compound, chemistry, Hepatocellular carcinoma, Drug Discovery, medicine, Molecular Medicine, Protease inhibitor (pharmacology)
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المؤلفون: Baldwin John J, Ashit K. Ganguly, He Huang, Laura L. Rokosz, Alan B. Cooper, Doll Ronald J, Chia-Yu Huang, John C. Reader, Ge Li, Corey Strickland, Tara M. Stauffer
المصدر: Bioorganic & Medicinal Chemistry Letters. 16:507-511
مصطلحات موضوعية: Molecular model, Stereochemistry, Farnesyltransferase, Clinical Biochemistry, Pharmaceutical Science, Drug design, chemistry.chemical_element, Zinc, Crystallography, X-Ray, Biochemistry, Chemical synthesis, Catalysis, Inhibitory Concentration 50, Mice, Structure-Activity Relationship, Peptide Library, Drug Discovery, Animals, Farnesyltranstransferase, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, Farnesyl-diphosphate farnesyltransferase, Binding Sites, biology, Chemistry, Organic Chemistry, Active site, Enzyme, NIH 3T3 Cells, biology.protein, Molecular Medicine
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المؤلفون: Nolan H. Sigal, Daniel Chelsky, Chia-Yu Huang, Ashit K. Ganguly, Laura L. Rokosz, Tara M. Stauffer, Baldwin John J, John C. Reader
المصدر: Bioorganic & Medicinal Chemistry Letters. 15:5537-5543
مصطلحات موضوعية: chemistry.chemical_classification, Farnesyl-diphosphate farnesyltransferase, biology, Stereochemistry, High-throughput screening, Farnesyltransferase, Organic Chemistry, Clinical Biochemistry, Imidazoles, Pharmaceutical Science, Biochemistry, Piperazines, Kinetics, Structure-Activity Relationship, Piperazine, chemistry.chemical_compound, Scintillation proximity assay, chemistry, Drug Discovery, biology.protein, Farnesyltranstransferase, Molecular Medicine, Enzyme Inhibitors, Molecular Biology, Tricyclic
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المؤلفون: Levy Odile Esther, B. Marten, Ashit K. Ganguly, Andrew Prongay, Patrick Pinto, Bruce A. Malcolm, Tin-Yau Chan, Parekh Tejal N, Santhanam Bama, Lim-Wilby Marguerita, Z. Zhu, Vincent Madison, Liwu Hong, Ashok Arasappan, Edwin Jao, Stephane L. Bogen, Hongwu Wang, Kemp Scott Jeffrey, F. G. Njoroge, Srikanth Venkatraman, Nanhua Yao, Kevin X. Chen, Nancy Butkiewicz, Mckittrick Brian A, John Pichardo, Henry M. Vaccaro, Liu Yi-Tsung, V. Girijavallabhan, Anil K. Saksena, Raymond G. Lovey, Richard N. Ingram, Haining Gu, Russell E. Pike, Frank Bennett, Xiaozheng Yang, Susan Y. Tamura
المصدر: Bioorganic & Medicinal Chemistry Letters. 15:4180-4184
مصطلحات موضوعية: chemistry.chemical_classification, Serine protease, Protease, biology, Chemistry, Stereochemistry, medicine.medical_treatment, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Biochemistry, Amino acid, Enzyme, Enzyme inhibitor, Drug Discovery, biology.protein, medicine, Molecular Medicine, Moiety, Potency, Protease inhibitor (pharmacology), Molecular Biology
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المؤلفون: Anil K. Saksena, Andrew T. McPhail, Tze-Ming Chan, Pradip R. Das, Ashit K. Ganguly, Rebecca Osterman, Birendra N. Pramanik, Viyyoor M. Girijavallabhan, Mccormick Jinping
المصدر: Tetrahedron Letters. 44:7997-8000
مصطلحات موضوعية: chemistry.chemical_compound, Olefin fiber, chemistry, Stereochemistry, Aryl, Organic Chemistry, Drug Discovery, Substituent, chemistry.chemical_element, Stereoselectivity, Biochemistry, Nitrogen
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المؤلفون: V. Girijavallabhan, Paul Kirschmeir, Patrick Pinto, Corey Strickland, F. George Njoroge, Bancha Vibulbhan, W. Robert Bishop, Ashit K. Ganguly
المصدر: Bioorganic & Medicinal Chemistry. 11:139-143
مصطلحات موضوعية: Models, Molecular, Farnesyl Protein Transferase, Pyridines, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Antineoplastic Agents, Carboxamide, Kidney, Tritium, Biochemistry, Chemical synthesis, Structure-Activity Relationship, chemistry.chemical_compound, Piperidines, Drug Discovery, medicine, Animals, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, Farnesyl-diphosphate farnesyltransferase, Alkyl and Aryl Transferases, biology, Organic Chemistry, Enzyme, Solubility, chemistry, Enzyme inhibitor, COS Cells, biology.protein, Molecular Medicine, Piperidine, Tricyclic
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المؤلفون: Ashit K. Ganguly, et al. et al.
المصدر: ChemInform. 45
مصطلحات موضوعية: chemistry.chemical_classification, Anti hiv activity, Protease, chemistry, HIV-1 protease, biology, Stereochemistry, medicine.medical_treatment, medicine, biology.protein, General Medicine, Affinities, Sulfonamide