المؤلفون: Bishop TR; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Subramanian C; Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN, USA., Bilotta EM; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Garnar-Wortzel L; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Ramos AR; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Zhang Y; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Asiaban JN; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Ott CJ; Massachusetts General Hospital Cancer Center, Charlestown, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA., Rock CO; Department of Infectious Diseases, St. Jude Children's Research Hospital, Memphis, TN, USA., Erb MA; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA. michaelerb@scripps.edu.

المصدر: Nature chemical biology [Nat Chem Biol] 2023 Oct; Vol. 19 (10), pp. 1215-1222. Date of Electronic Publication: 2023 May 01.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Histone Acetyltransferases*/metabolism , Neoplasms*, Humans ; p300-CBP Transcription Factors/metabolism ; Acetyl Coenzyme A/metabolism ; Protein Binding

المؤلفون: Zhang Y; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Remillard D; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Onubogu U; Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, FL, USA., Karakyriakou B; Massachusetts General Hospital Cancer Center, Charlestown, MA, USA., Asiaban JN; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Ramos AR; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Bowland K; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Bishop TR; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Barta PA; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Nance S; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA., Durbin AD; Department of Oncology, St. Jude Children's Research Hospital, Memphis, TN, USA., Ott CJ; Massachusetts General Hospital Cancer Center, Charlestown, MA, USA.; Department of Medicine, Harvard Medical School, Boston, MA, USA.; Broad Institute of MIT & Harvard, Cambridge, MA, USA., Janiszewska M; Department of Molecular Medicine, The Herbert Wertheim UF Scripps Institute for Biomedical Innovation & Technology, Jupiter, FL, USA., Cravatt BF; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA., Erb MA; Department of Chemistry, The Scripps Research Institute, La Jolla, CA, USA. michaelerb@scripps.edu.

المصدر: Nature structural & molecular biology [Nat Struct Mol Biol] 2023 Aug; Vol. 30 (8), pp. 1160-1171. Date of Electronic Publication: 2023 Jul 24.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101186374 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1545-9985 (Electronic) Linking ISSN: 15459985 NLM ISO Abbreviation: Nat Struct Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: Multiple Myeloma*/genetics , Neuroblastoma*/genetics, Humans ; Mi-2 Nucleosome Remodeling and Deacetylase Complex/genetics ; Mi-2 Nucleosome Remodeling and Deacetylase Complex/metabolism ; Histone Deacetylase 1/genetics ; Histone Deacetylase 1/metabolism ; Gene Expression Regulation ; Nucleosomes ; Histone Deacetylase 2/genetics ; Histone Deacetylase 2/metabolism

المؤلفون: Asiaban JN; School of Medicine, University of California San Francisco, San Francisco, California., Patel S; School of Medicine, University of California San Francisco, San Francisco, California., Ormseth CH; School of Medicine, University of California San Francisco, San Francisco, California., Donohue KC; School of Medicine, University of California San Francisco, San Francisco, California., Wallin D; Department of Emergency Medicine, University of California San Francisco, San Francisco, California., Wang RC; Department of Emergency Medicine, University of California San Francisco, San Francisco, California., Raven MC; Department of Emergency Medicine, University of California San Francisco, San Francisco, California; Philip R. Lee Institute for Health Policy Studies, University of California San Francisco, San Francisco, California.

المصدر: The Journal of emergency medicine [J Emerg Med] 2023 Apr; Vol. 64 (4), pp. 476-480. Date of Electronic Publication: 2023 Mar 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 8412174 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 0736-4679 (Print) Linking ISSN: 07364679 NLM ISO Abbreviation: J Emerg Med Subsets: MEDLINE

مواضيع طبية MeSH: Medicare* , Advance Care Planning*, Aged ; Humans ; United States ; Retrospective Studies ; Pilot Projects ; Emergency Service, Hospital

المؤلفون: Garnar-Wortzel L; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States., Bishop TR; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States., Kitamura S; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, California 92037, United States.; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California 92037, United States., Milosevich N; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States., Asiaban JN; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States., Zhang X; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States., Zheng Q; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States., Chen E; California Institute for Biomedical Research, The Scripps Research Institute, La Jolla, California 92037, United States., Ramos AR; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States., Ackerman CJ; California Institute for Biomedical Research, The Scripps Research Institute, La Jolla, California 92037, United States., Hampton EN; California Institute for Biomedical Research, The Scripps Research Institute, La Jolla, California 92037, United States., Chatterjee AK; California Institute for Biomedical Research, The Scripps Research Institute, La Jolla, California 92037, United States., Young TS; California Institute for Biomedical Research, The Scripps Research Institute, La Jolla, California 92037, United States., Hull MV; California Institute for Biomedical Research, The Scripps Research Institute, La Jolla, California 92037, United States., Sharpless KB; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States., Cravatt BF; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States., Wolan DW; Department of Molecular Medicine, The Scripps Research Institute, La Jolla, California 92037, United States.; Department of Integrative Structural and Computational Biology, The Scripps Research Institute, La Jolla, California 92037, United States., Erb MA; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States.

المصدر: ACS central science [ACS Cent Sci] 2021 May 26; Vol. 7 (5), pp. 815-830. Date of Electronic Publication: 2021 Apr 30.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: ACS Publications Country of Publication: United States NLM ID: 101660035 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2374-7943 (Print) Linking ISSN: 23747943 NLM ISO Abbreviation: ACS Cent Sci Subsets: PubMed not MEDLINE

المؤلفون: López-Erauskin J, Tadokoro T, Baughn MW, Myers B, McAlonis-Downes M, Chillon-Marinas C, Asiaban JN, Artates J, Bui AT, Vetto AP, Lee SK, Le AV, Sun Y, Jambeau M, Boubaker J, Swing D, Qiu J, Hicks GG, Ouyang Z, Fu XD, Tessarollo L, Ling SC, Parone PA, Shaw CE, Marsala M, Lagier-Tourenne C, Cleveland DW, Da Cruz S

المصدر: Neuron [Neuron] 2020 Apr 22; Vol. 106 (2), pp. 354.

نوع المنشور: Journal Article; Published Erratum

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 8809320 Publication Model: Print Cited Medium: Internet ISSN: 1097-4199 (Electronic) Linking ISSN: 08966273 NLM ISO Abbreviation: Neuron Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: Asiaban JN; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States., Milosevich N; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States., Chen E; Calibr at Scripps Research, La Jolla, California 92037, United States., Bishop TR; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States., Wang J; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States., Zhang Y; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States., Ackerman CJ; Calibr at Scripps Research, La Jolla, California 92037, United States., Hampton EN; Calibr at Scripps Research, La Jolla, California 92037, United States., Young TS; Calibr at Scripps Research, La Jolla, California 92037, United States., Hull MV; Calibr at Scripps Research, La Jolla, California 92037, United States., Cravatt BF; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States., Erb MA; Department of Chemistry, The Scripps Research Institute, La Jolla, California 92037, United States.

المصدر: ACS chemical biology [ACS Chem Biol] 2020 Apr 17; Vol. 15 (4), pp. 895-903. Date of Electronic Publication: 2020 Mar 19.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Biological Assay/*methods , High-Throughput Screening Assays/*methods , Small Molecule Libraries/*analysis , Small Molecule Libraries/*metabolism , Transcriptional Elongation Factors/*metabolism, Cell Line, Tumor ; Drug Discovery ; HEK293 Cells ; Humans ; Ligands ; Protein Binding ; Protein Domains/drug effects ; Small Molecule Libraries/pharmacology ; Transcriptional Elongation Factors/antagonists & inhibitors

المؤلفون: López-Erauskin J; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093, USA., Tadokoro T; Department of Anesthesiology, University of California at San Diego, La Jolla, CA 92093, USA., Baughn MW; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093, USA., Myers B; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093, USA., McAlonis-Downes M; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093, USA., Chillon-Marinas C; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093, USA., Asiaban JN; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093, USA., Artates J; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093, USA., Bui AT; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093, USA., Vetto AP; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093, USA., Lee SK; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093, USA., Le AV; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093, USA., Sun Y; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093, USA., Jambeau M; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093, USA., Boubaker J; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093, USA., Swing D; Mouse Cancer Genetics Program, National Cancer Institute, Frederick, MD, 21702, USA., Qiu J; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA 92093, USA., Hicks GG; Regenerative Medicine Program and Department of Biochemistry & Medical Genetics, University of Manitoba, Winnipeg, R3T 2N2, Canada., Ouyang Z; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA 92093, USA., Fu XD; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA 92093, USA., Tessarollo L; Mouse Cancer Genetics Program, National Cancer Institute, Frederick, MD, 21702, USA., Ling SC; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093, USA., Parone PA; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093, USA., Shaw CE; United Kingdom Dementia Research Institute Centre, Maurice Wohl Clinical Neuroscience Institute, Institute of Psychiatry, Psychology and Neuroscience, King's College London, SE5 9NU London, U.K; Centre for Brain Research, University of Auckland, Auckland, New Zealand., Marsala M; Department of Anesthesiology, University of California at San Diego, La Jolla, CA 92093, USA., Lagier-Tourenne C; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093, USA; Department of Neurosciences, University of California at San Diego, La Jolla, CA 92093, USA., Cleveland DW; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093, USA; Department of Cellular and Molecular Medicine, University of California at San Diego, La Jolla, CA 92093, USA; Department of Neurosciences, University of California at San Diego, La Jolla, CA 92093, USA. Electronic address: dcleveland@ucsd.edu., Da Cruz S; Ludwig Institute for Cancer Research, University of California at San Diego, La Jolla, CA 92093, USA. Electronic address: sdacruz@ucsd.edu.

المصدر: Neuron [Neuron] 2018 Nov 21; Vol. 100 (4), pp. 816-830.e7. Date of Electronic Publication: 2018 Oct 18.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 8809320 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4199 (Electronic) Linking ISSN: 08966273 NLM ISO Abbreviation: Neuron

مواضيع طبية MeSH: Amyotrophic Lateral Sclerosis/*genetics , Axons/*physiology , Frontotemporal Dementia/*genetics , Loss of Function Mutation/*genetics , Protein Biosynthesis/*physiology , RNA-Binding Protein FUS/*genetics, Amyotrophic Lateral Sclerosis/metabolism ; Amyotrophic Lateral Sclerosis/pathology ; Animals ; Axons/pathology ; Cells, Cultured ; Female ; Frontotemporal Dementia/metabolism ; Frontotemporal Dementia/pathology ; Hippocampus/metabolism ; Hippocampus/pathology ; Humans ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Pregnancy ; RNA-Binding Protein FUS/biosynthesis