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المؤلفون: Mahdia Benkhoucha, Mashal Claude Ahmed, Dominique Baeten, Romain Marignier, Jose Boucraut, Olivier Casez, Michael Hahne, Jean Boutonnat, Corinne Sonrier, Benoit Manfroi, Laurie Baert, Patrice N. Marche, Nathalie Sturm, Marine Tessier, Patrice H. Lalive, Romain R. Vivès, Bertrand Huard, Cyril Rivat, Catherine Ghezzi, Hans Lassmann, Pascal Schneider, Natalia Popa, Gilda Raguenez, Alexis Broisat, Hugues Lortat-Jacob, Mitra Ahmadi
المساهمون: Institute for Advanced Biosciences / Institut pour l'Avancée des Biosciences (Grenoble) (IAB), Centre Hospitalier Universitaire [Grenoble] (CHU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Etablissement français du sang - Auvergne-Rhône-Alpes (EFS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Department of Pathology and Immunology [Geneva, Switzerland] (Clinical Pathology Division), University of Geneva [Switzerland]-Geneva University Hospitals - HUG [Switzerland], Centre de recherche en neurobiologie - neurophysiologie de Marseille (CRN2M), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Département d'anatomie et cythologie pathologique, CHU Grenoble-Hôpital Michallon, Centre Hospitalier Universitaire [Grenoble] (CHU), Centre de recherche en neurosciences de Lyon (CRNL), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Université Jean Monnet [Saint-Étienne] (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Radiopharmaceutiques biocliniques (LRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Institut des Neurosciences de Montpellier - Déficits sensoriels et moteurs (INM), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Institut de Génétique Moléculaire de Montpellier (IGMM), Centre National de la Recherche Scientifique (CNRS)-Université de Montpellier (UM), Department of Clinical Immunology and Rheumatology [Academic Medical Center, Amsterdam], University of Amsterdam [Amsterdam] (UvA), Institut de biologie structurale (IBS - UMR 5075 ), Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Direction de Recherche Fondamentale (CEA) (DRF (CEA)), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Centre National de la Recherche Scientifique (CNRS), Department of Biochemistry [Lausanne], Université de Lausanne (UNIL), University of Vienna [Vienna], Department of Clinical Neurosciences [Geneva, Switzerland], Unit of Neuroimmunology and Neuromuscular Diseases [Geneva, Switzerland] (Division of Neurology), Geneva University Hospitals - HUG [Switzerland]-Geneva University Hospitals - HUG [Switzerland], This work was supported by Grenoble Alpes University (B.H.), the National Institute of Health and Medical Research (B.H.), the Association for Aid to Multiple Sclerosis Research (B.H.), the National Agency for Research (program center of excellence in neurodegeneration obtained within the Grenoble excellence in neurodegeneration network, B.H.), the Swiss National Science Foundation (310030_156961/310030_176256 to PS and 310030_153164/310030_176678 to PL), and the Swiss Multiple Sclerosis Society (P.L.)., Clinical Immunology and Rheumatology, AII - Inflammatory diseases, Centre Hospitalier Universitaire [Grenoble] (CHU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Etablissement français du sang - Auvergne-Rhône-Alpes (EFS)-Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019]), Université de Genève = University of Geneva (UNIGE)-Geneva University Hospitals - HUG [Switzerland], Centre de recherche en neurosciences de Lyon - Lyon Neuroscience Research Center (CRNL), Université de Lyon-Université de Lyon-Université Jean Monnet - Saint-Étienne (UJM)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut des Neurosciences de Montpellier (INM), Université de Montpellier (UM)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Université Grenoble Alpes [2016-2019] (UGA [2016-2019])-Institut de Recherche Interdisciplinaire de Grenoble (IRIG), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA), Université de Lausanne = University of Lausanne (UNIL), Grenoble Alpes University, the National Institute of Health and Medical Research, the Association for Aid to Multiple Sclerosis Research), the National Agency for Research (program center of excellence in neurodegeneration obtained within the Grenoble excellence in neurodegeneration network, the Swiss National Science Foundation (310030_156961/310030_176256 to PS and 310030_153164/310030_176678 )The Swiss Multiple Sclerosis Society, MARCHE, Patrice
المصدر: Annals of Neurology
Annals of Neurology, Wiley, 2019, 85 (3), pp.406-420. ⟨10.1002/ana.25415⟩
Annals of neurology, vol. 85, no. 3, pp. 406-420
Annals of neurology, 85(3), 406-420. John Wiley and Sons Inc.
Annals of Neurology, 2019, 85 (3), pp.406-420. ⟨10.1002/ana.25415⟩مصطلحات موضوعية: Male, 0301 basic medicine, T-Lymphocytes, Mice, chemistry.chemical_compound, 0302 clinical medicine, B-Cell Activating Factor, Medicine, Mice, Knockout, Reverse Transcriptase Polymerase Chain Reaction, Chondroitin Sulfates, Middle Aged, Immunohistochemistry, Interleukin-10, 3. Good health, Interleukin 10, Neurology, Adult, Aged, Animals, Astrocytes/immunology, Astrocytes/metabolism, Astrocytes/pathology, B-Cell Activating Factor/metabolism, Cell Proliferation, Chondroitin Sulfate Proteoglycans/metabolism, Chondroitin Sulfates/metabolism, Cytokines/immunology, Disease Models, Animal, Encephalomyelitis, Autoimmune, Experimental/immunology, Encephalomyelitis, Autoimmune, Experimental/metabolism, Encephalomyelitis, Autoimmune, Experimental/pathology, Female, Humans, Interleukin-10/immunology, Macrophages/pathology, Multiple Sclerosis/immunology, Multiple Sclerosis/metabolism, Multiple Sclerosis/pathology, T-Lymphocytes/immunology, Tumor Necrosis Factor Ligand Superfamily Member 13/genetics, Tumor Necrosis Factor Ligand Superfamily Member 13/metabolism, Tumor Necrosis Factor Ligand Superfamily Member 13/pharmacology, Cytokines, [SDV.IMM]Life Sciences [q-bio]/Immunology, Tumor necrosis factor alpha, medicine.symptom, Encephalomyelitis, Autoimmune, Experimental, Multiple Sclerosis, [SDV.IMM] Life Sciences [q-bio]/Immunology, Tumor Necrosis Factor Ligand Superfamily Member 13, Inflammation, 03 medical and health sciences, [SDV.BBM] Life Sciences [q-bio]/Biochemistry, Molecular Biology, [SDV.BBM]Life Sciences [q-bio]/Biochemistry, Molecular Biology, B-cell activating factor, Autoimmune encephalitis, business.industry, Macrophages, Multiple sclerosis, medicine.disease, 030104 developmental biology, Chondroitin Sulfate Proteoglycans, chemistry, Chondroitin sulfate proteoglycan, Astrocytes, Immunology, Cytokine secretion, Neurology (clinical), business, 030217 neurology & neurosurgery
وصف الملف: application/pdf
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المؤلفون: Pierre J. Magistretti, Igor Allaman, Nicole Schaeren-Wiemers, Melanie Gentner, J. Tschopp, Thomas Zeis, Kate Schroder
المصدر: Brain Behavior and Immunity
Brain behavior and immunity
Brain, Behavior, and Immunity, vol. 48, pp. 313-325مصطلحات موضوعية: Adult, Male, Astrocyte–neuron lactate shuttle, Multiple Sclerosis, Inflammasomes, Central nervous system, Immunology, Astrocyte-neuron lactate shuttle, Gene Expression, Biology, Mice, Young Adult, Behavioral Neuroscience, Aged, Aged, 80 and over, Animals, Astrocytes/immunology, Astrocytes/metabolism, Cerebral Cortex/immunology, Cerebral Cortex/metabolism, Female, Humans, Middle Aged, Multiple Sclerosis/genetics, Multiple Sclerosis/immunology, Neurons/immunology, Neurons/metabolism, Signal Transduction/genetics, Signal Transduction/immunology, Downregulation and upregulation, Gene expression, medicine, Neurons, Brain energy homeostasis, Regulation of gene expression, Gray matter pathology, Endocrine and Autonomic Systems, Multiple sclerosis, Inflammasome, Cerebral cortex, medicine.disease, medicine.anatomical_structure, Astrocytes, Normal appearing gray matter, Neuroscience, Signal Transduction, medicine.drug, Astrocyte
وصف الملف: application/pdf
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المؤلفون: Koji Yamanaka, Jari Koistinaho, Douglas T. Golenbock, Terrence Town, Guy C. Brown, Erik Boddeke, Monica J. Carson, V. Hugh Perry, Gabor C. Petzold, Olga Garaschuk, David J. Brooks, Markus P. Kummer, John C.S. Breitner, Nikolaus Deigendesch, Frederic Brosseron, Greg M. Cole, Nicolas G. Bazan, Stéphane Hunot, Michael T. Heneka, Dave Morgan, Javier Vitorica, Gary E. Landreth, Clive Holmes, Eicke Latz, Bertrand Joseph, Annett Halle, Charles A. Dinarello, Mari L. Shinohara, Joseph El Khoury, Douglas L. Feinstein, Andreas H. Jacobs, Tony Wyss-Coray, Alexei Verkhratsky, Karl Herrup, Richard M. Ransohoff, Sally A. Frautschy, Bente Finsen
المصدر: The Lancet. Neurology, vol 14, iss 4
ResearcherID
The lancet/ Neurology 14(4), 388-405 (2015). doi:10.1016/S1474-4422(15)70016-5
Lancet Neurology, 14, 388-405
Heneka, MT; Carson, MJ; Khoury, JE; Landreth, GE; Brosseron, F; Feinstein, DL; et al.(2015). Neuroinflammation in Alzheimer's disease. The Lancet Neurology, 14(4), 388-405. doi: 10.1016/S1474-4422(15)70016-5. UCLA: Retrieved from: http://www.escholarship.org/uc/item/99h2f9m1
Lancet Neurology, 14, 4, pp. 388-405
Heneka, M T, Carson, M J, Khoury, J E, Landreth, G E, Brosseron, F, Feinstein, D L, Jacobs, A H, Wyss-Coray, T, Vitorica, J, Ransohoff, R M, Herrup, K, Frautschy, S A, Finsen, B, Brown, G C, Verkhratsky, A, Yamanaka, K, Koistinaho, J, Latz, E, Halle, A, Petzold, G C, Town, T, Morgan, D, Shinohara, M L, Perry, V H, Holmes, C, Bazan, N G, Brooks, D J, Hunot, S, Joseph, B, Deigendesch, N, Garaschuk, O, Boddeke, E, Dinarello, C A, Breitner, J C, Cole, G M, Golenbock, D T & Kummer, M P 2015, ' Neuroinflammation in Alzheimer's disease ', Lancet Neurology, vol. 14, no. 4, pp. 388-405 . https://doi.org/10.1016/S1474-4422(15)70016-5
The Lancet Neurologyمصطلحات موضوعية: Aging, MILD COGNITIVE IMPAIRMENT, lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4], Disease, Alzheimer's Disease, Systemic inflammation, Severity of Illness Index, Inflammation/diagnosis, immunology [Inflammation], Aetiology, metabolism [Inflammation], blood [Biomarkers], Microglia, complications [Obesity], pathology [Microglia], RANDOMIZED CONTROLLED-TRIAL, immunology [Microglia], Disease Progression, Locus Coeruleus, Anti-Inflammatory Agents, Non-Steroidal/therapeutic use, Central nervous system, Clinical Sciences, CEREBRAL AMYLOID ANGIOPATHY, Article, administration & dosage [Nootropic Agents], Phagocytosis, Alzheimer Disease, Humans, Inflammation Mediators/immunology, NITRIC-OXIDE SYNTHASE, GENOME-WIDE ASSOCIATION, Locus Coeruleus/pathology, pathology [Locus Coeruleus], Animal, Prevention, Inflammatory and immune system, CENTRAL-NERVOUS-SYSTEM, Immunity, Immunity, Innate, diagnosis [Inflammation], immunology [Alzheimer Disease], nervous system, Astrocytes, Brain Injuries, Immunology, Dementia, Neurology (clinical), Obesity/complications, Neuroscience, Biomarkers, Protein Folding, Microglia/immunology, Anti-Inflammatory Agents, genetics [Alzheimer Disease], Neurodegenerative, prevention & control [Alzheimer Disease], pathology [Alzheimer Disease], Risk Factors, Brain Injuries/complications, complications [Brain Injuries], 2.1 Biological and endogenous factors, Innate, Nootropic Agents, therapeutic use [Anti-Inflammatory Agents, Non-Steroidal], pathology [Astrocytes], Clinical Trials as Topic, Nootropic Agents/administration & dosage, Anti-Inflammatory Agents, Non-Steroidal, Pattern recognition receptor, medicine.anatomical_structure, cerebrospinal fluid [Biomarkers], Neurological, medicine.symptom, Inflammation Mediators, immunology [Inflammation Mediators], Non-Steroidal, metabolism [Alzheimer Disease], Astrocytes/immunology, ANTIINFLAMMATORY PREVENTION TRIAL, TRAUMATIC BRAIN-INJURY, immunology [Astrocytes], metabolism [Brain Injuries], POSITRON-EMISSION-TOMOGRAPHY, metabolism [Obesity], Acquired Cognitive Impairment, medicine, Animals, ddc:610, Obesity, TRANSGENIC MOUSE MODEL, Neuroinflammation, Inflammation, Alzheimer Disease/genetics, Innate immune system, Neurology & Neurosurgery, business.industry, metabolism [Inflammation Mediators], Neurosciences, Alzheimer's Disease including Alzheimer's Disease Related Dementias (AD/ADRD), Brain Disorders, Disease Models, Animal, Disease Models, Immunization, business, Biomarkers/blood
وصف الملف: application/pdf
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المؤلفون: Frans G. M. Kroese, Jacques De Keyser, Nadine Wilczak, Jan Wilschut, Daniel Chesik, Lisa Glazenburg, E Zeinstra
المساهمون: Faculteit Medische Wetenschappen/UMCG, Translational Immunology Groningen (TRIGR), Gerontology
المصدر: Journal of Neuroimmunology, 179(1-2), 191-195. ELSEVIER SCIENCE BV
مصطلحات موضوعية: Histocompatibility Antigens Class II/*biosynthesis, Wistar, Phenylephrine/pharmacology, multiple sclerosis, Phenylephrine, Immunology and Allergy, 5-HT4 agonists, Receptor, Cells, Cultured, Cisapride, Cultured, biology, MULTIPLE-SCLEROSIS, Cisapride/pharmacology, Immunohistochemistry, Benzofurans/pharmacology, Serotonin Receptor Agonists, RECEPTORS, Neurology, B7-1 Antigen, Astrocytes/immunology/*metabolism, Serotonin Agonists/*pharmacology, Adrenergic alpha-Agonists, medicine.drug, Agonist, PLAQUES, medicine.medical_specialty, B7 co-stimulatory molecules, medicine.drug_class, Immunology, Adrenergic alpha-Agonists/pharmacology, RATS, IA-ANTIGEN, Interferon-gamma, Immune system, Antigen, Internal medicine, cAMP, medicine, Animals, Rats, Wistar, Antigens, 5-HT receptor, Benzofurans, MHC class II, Prucalopride, LESIONS, CENTRAL-NERVOUS-SYSTEM, Histocompatibility Antigens Class II, astrocytes, Serotonin/*drug effects, CD80/*biosynthesis, Endocrinology, TISSUE, Receptors, Serotonin, CELLS, biology.protein, Neurology (clinical), Immunostaining, Interferon Type II/immunology/*metabolism
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المؤلفون: Jacques De Keyser, Esther Zeinstra, Elliot M. Frohman
المساهمون: Van der Zee lab, Gerontology, Vrije Universiteit Brussel, Gerontologie
المصدر: Archives of Neurology, 60(1), 132-136. AMER MEDICAL ASSOC
مصطلحات موضوعية: Astrocytes/immunology, Multiple Sclerosis, Antigen-Presenting Cells, BETA-ADRENERGIC RECEPTORS, Major histocompatibility complex, MYELIN BASIC-PROTEIN, Immune system, Arts and Humanities (miscellaneous), medicine, Antigen-Presenting Cells/immunology, IA ANTIGEN EXPRESSION, Humans, Pathophysiology of multiple sclerosis, Multiple Sclerosis/immunology, NITRIC-OXIDE SYNTHASE, Antigen-presenting cell, Neuroinflammation, Microglia, biology, Multiple sclerosis, CENTRAL-NERVOUS-SYSTEM, CLASS-II MOLECULES, HUMAN-FETAL ASTROCYTES, medicine.disease, MAJOR HISTOCOMPATIBILITY COMPLEX, medicine.anatomical_structure, Astrocytes, Immunology, biology.protein, B7 COSTIMULATORY MOLECULES, Neurology (clinical), RAT CEREBRAL-CORTEX, Neuroscience, Astrocyte, Human
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f21947b650715ced9f9b48686fc5fe93
https://pubmed.ncbi.nlm.nih.gov/12533101 -
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المؤلفون: Jacques De Keyser, Esther Zeinstra, Nadine Wilczak
المساهمون: Gerontology, Van der Zee lab
المصدر: Journal of Neuroimmunology, 135(1-2), 166-171. ELSEVIER SCIENCE BV
مصطلحات موضوعية: Male, Proteolipid protein 1, T-Lymphocytes, ENCEPHALITOGENIC T-CELLS, multiple sclerosis, MYELIN BASIC-PROTEIN, B7-1, B7-2, Antigen-Presenting Cells/physiology, Immunology and Allergy, IA ANTIGEN EXPRESSION, Membrane Glycoproteins, Chronic Active, CLASS-II MOLECULES, Antigens, CD/*analysis, Middle Aged, Immunohistochemistry, Antigens, CD80/*analysis, Cell biology, medicine.anatomical_structure, Neurology, B7-1 Antigen, Female, Astrocytes/*immunology/physiology, Adult, Immunology, Central nervous system, Antigen-Presenting Cells, Biology, Major histocompatibility complex, Antigen, Antigens, CD, medicine, PROTEOLIPID PROTEIN, Humans, Aged, Multiple sclerosis, CENTRAL-NERVOUS-SYSTEM, astrocytes, IN-VITRO, co-stimulatory molecules, GAMMA, medicine.disease, In vitro, Myelin basic protein, Chronic Disease, biology.protein, COSTIMULATORY MOLECULES, Neurology (clinical), B7-2 Antigen, HUMAN MICROGLIA, aged, 80 and over
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d98eb093c84ce4efe5c6dd8dc6a14f2b
https://biblio.vub.ac.be/vubir/reactive-astrocytes -in-chronic-active-lesions-of-multiple-sclerosis-express-costimulatory-molecules-b71-and-b72(40f1f8fa-d834-4bff-bfa6-0ff7b3c4d817).html -
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المؤلفون: José Boucraut, Shozo Izui, Michel Khrestchatisky, Simone Varriale, Dominique Bernard, Sophie Desplat-Jego, Rafik Terra, Yves Chicheportiche, Rita Creidy
المصدر: Journal of Neuroimmunology, Vol. 133, No 1-2 (2002) pp. 116-123
مصطلحات موضوعية: Genetically modified mouse, Central Nervous System, Cell type, Encephalomyelitis, Autoimmune, Experimental, Disease Susceptibility/immunology, Encephalomyelitis, Autoimmune, Experimental/genetics/immunology/ metabolism, Encephalomyelitis, Transgene, Immunology, Mice, Transgenic, Microglia/immunology/ metabolism, ddc:616.07, Biology, Inflammation Mediators/ pharmacology, Proinflammatory cytokine, Mice, medicine, Immunology and Allergy, Animals, RNA, Messenger, Receptor, Cytokine TWEAK, Cells, Cultured, Astrocytes/immunology/ metabolism, Cell Division/drug effects/genetics/immunology, Gene Expression Regulation/immunology, medicine.disease, Cell biology, Central Nervous System/growth & development/immunology/ metabolism, medicine.anatomical_structure, Neurology, Gene Expression Regulation, Astrocytes, Tumor Necrosis Factors, Disease Progression, RNA, Messenger/immunology/metabolism, Neurology (clinical), Disease Susceptibility, Microglia, Carrier Proteins/ genetics/pharmacology, Inflammation Mediators, Apoptosis Regulatory Proteins, Carrier Proteins, Cell Division, Astrocyte
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المؤلفون: Tobias Suter, Bernard Mach, Ursula Malipiero, Luc A. Otten, Walter Reith, Burkhard Ludewig, Annick Muelethaler-Mottet, Adriano Fontana
المصدر: European Journal of Immunology, Vol. 30, No 3 (2000) pp. 794-802
مصطلحات موضوعية: Central Nervous System, Transcriptional Activation, Astrocytes/immunology, Encephalomyelitis, Autoimmune, Experimental, RNA, Messenger/genetics/metabolism, Antigens, CD11/metabolism, Microglia/immunology, Immunology, Central nervous system, Genes, MHC Class II, chemical and pharmacologic phenomena, Biology, ddc:616.07, Myelin oligodendrocyte glycoprotein, MHC Class II Gene, Macrophages/immunology/metabolism/pathology, Mice, Pregnancy, medicine, CIITA, Immunology and Allergy, Animals, RNA, Messenger, Promoter Regions, Genetic, Spinal Cord/immunology/metabolism/pathology, B cell, MHC class II, Microglia, CD11 Antigens, Macrophages, Dendritic cell, Dendritic Cells, Immunohistochemistry, Encephalomyelitis, Autoimmune, Experimental/ genetics/ immunology/pathology, Mice, Inbred C57BL, medicine.anatomical_structure, Spinal Cord, Astrocytes, Central Nervous System/immunology/metabolism/pathology, Dendritic Cells/ immunology/metabolism/pathology, biology.protein, Female
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المؤلفون: Kaltschmidt, Christian, Kaltschmidt, Barbara, Lannes-Vieira, J., Kreutzberg, G. W., Wekerle, H., Baeuerle, P. A., Gehrmann, J.
مصطلحات موضوعية: Astrocytes/immunology, Inbred Lew, Animals, Spinal Cord/immunology, Female, Encephalomyelitis, Immunohistochemistry, NF-kappa B/*immunology, Microglia/*immunology, Rats, Experimental/*immunology/pathology, Autoimmune
URL الوصول: https://explore.openaire.eu/search/publication?articleId=od______2294::1c7102350edcedd46d1dbdc4fedd9db6
https://pub.uni-bielefeld.de/record/2398807
Full Text via ClinicalKey