المؤلفون: Attfield, KE, Jensen, LT, Kaufmann, M, Friese, MA, Fugger, L

المصدر: Attfield, K E, Jensen, L T, Kaufmann, M, Friese, M A & Fugger, L 2022, ' The immunology of multiple sclerosis ', Nature Reviews. Immunology, vol. 22, no. 12, pp. 734-750 . https://doi.org/10.1038/s41577-022-00718-z

مصطلحات موضوعية: History, Multiple Sclerosis, Phenotype, Humans, Computer Science Applications, Education

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::225d2d52eff2ab5d54522a9e8a286b5d
https://doi.org/10.1038/s41577-022-00718-z

المؤلفون: Moutsianas, L, Jostins, L, Beecham, AH, Dilthey, AT, Xifara, DK, Ban, M, Shah, TS, Patsopoulos, NA, Alfredsson, L, Anderson, CA, Attfield, KE, Baranzini, SE, Barrett, J, Binder, TMC, Booth, D, Buck, D, Celius, EG, Cotsapas, C, D'Alfonso, S, Dendrou, CA, Donnelly, P, Dubois, B, Fontaine, B, Fugger, L, Goris, A, Gourraud, PA, Graetz, C, Hemmer, B, Hillert, J, Kockum, I, Leslie, S, Lill, CM, Martinelli-Boneschi, F, Oksenberg, JR, Olsson, T, Oturai, A, Saarela, J, Sondergaard, HB, Spurkland, A, Taylor, B, Winkelmann, J, Zipp, F, Haines, JL, Pericak-Vance, MA, Spencer, CCA, Stewart, G, Hafler, DA, Ivinson, AJ, Harbo, HF, Hauser, SL, De Jager, PL, Compston, A, McCauley, JL, Sawcer, S, McVean, G

المصدر: Nature genetics. 47(10):1107

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:132112956

المؤلفون: Dendrou, CA, Cortes, A, Shipman, L, Evans, HG, Attfield, KE, Jostins, L, Barber, T, Kaur, G, Kuttikkatte, SB, Leach, OA, Desel, C, Faergeman, SL, Cheeseman, J, Neville, MJ, Sawcer, S, Compston, A, Johnson, AR, Everett, C, Bell, JI, Karpe, F, Ultsch, M, Eigenbrot, C, McVean, G, Fugger, L

المساهمون: Sawcer, Stephen [0000-0001-7685-0974], Apollo - University of Cambridge Repository

مصطلحات موضوعية: CD4-Positive T-Lymphocytes, Male, Genotype, Protein Conformation, Quantitative Trait Loci, Mutation, Missense, Autoimmunity, Polymorphism, Single Nucleotide, Autoimmune Diseases, Epigenesis, Genetic, Mice, Animals, Humans, Genetic Association Studies, Recombination, Genetic, TYK2 Kinase, Sequence Analysis, RNA, Homozygote, Genetic Variation, Genomics, Janus Kinase 2, HEK293 Cells, Phenotype, Immune System, Leukocytes, Mononuclear, Cytokines, Female, Transcriptome, Signal Transduction

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c8a11182731ee452ca491b63d96777e4
https://www.repository.cam.ac.uk/handle/1810/262725

المؤلفون: Jensen LT; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark.; Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK., Attfield KE; Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK., Fugger L; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark. lars.fugger@ndcn.ox.ac.uk.; Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK. lars.fugger@ndcn.ox.ac.uk.; MRC Translational Immune Discovery Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK. lars.fugger@ndcn.ox.ac.uk.

المصدر: Nature immunology [Nat Immunol] 2024 Mar; Vol. 25 (3), pp. 385-386.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature America Inc Country of Publication: United States NLM ID: 100941354 Publication Model: Print Cited Medium: Internet ISSN: 1529-2916 (Electronic) Linking ISSN: 15292908 NLM ISO Abbreviation: Nat Immunol Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: Lippert AH; Department of Chemistry, University of Cambridge, Cambridge, UK., Paluch C; MRC Human Immunology Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK; Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK; Nuffield Department of Medicine, University of Oxford, Oxford, UK; MiroBio Ltd, Winchester House, Oxford Science Park, Oxford, UK., Gaglioni M; MRC Human Immunology Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK; Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK., Vuong MT; MRC Human Immunology Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK; Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK., McColl J; Department of Chemistry, University of Cambridge, Cambridge, UK., Jenkins E; MRC Human Immunology Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK; Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK., Fellermeyer M; MRC Human Immunology Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK; Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK., Clarke J; MRC Human Immunology Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK; Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK., Sharma S; MRC Human Immunology Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK; Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK., Moreira da Silva S; MiroBio Ltd, Winchester House, Oxford Science Park, Oxford, UK., Akkaya B; MRC Human Immunology Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK; Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Anzilotti C; MRC Human Immunology Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK; Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK; Nuffield Department of Medicine, University of Oxford, Oxford, UK., Morgan SH; MRC Human Immunology Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK; Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK., Jessup CF; MRC Human Immunology Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK; Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK., Körbel M; Department of Chemistry, University of Cambridge, Cambridge, UK., Gileadi U; MRC Human Immunology Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK., Leitner J; Division of Immune Receptors and T cell Activation, Institute of Immunology, Medical University of Vienna, Vienna, Austria., Knox R; MRC Human Immunology Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK; Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK., Chirifu M; MRC Human Immunology Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK; Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK., Huo J; MRC Human Immunology Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK; Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK., Yu S; MRC Human Immunology Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK; Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK., Ashman N; MRC Human Immunology Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK; Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK., Lui Y; MRC Human Immunology Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK; Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK., Wilkinson I; Absolute Antibody Ltd, Redcar, Cleveland, UK., Attfield KE; MRC Human Immunology Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK; Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK., Fugger L; MRC Human Immunology Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK; Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK., Robertson NJ; MiroBio Ltd, Winchester House, Oxford Science Park, Oxford, UK., Lynch CJ; MiroBio Ltd, Winchester House, Oxford Science Park, Oxford, UK., Murray L; MiroBio Ltd, Winchester House, Oxford Science Park, Oxford, UK., Steinberger P; Division of Immune Receptors and T cell Activation, Institute of Immunology, Medical University of Vienna, Vienna, Austria., Santos AM; MRC Human Immunology Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK; Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK., Lee SF; Department of Chemistry, University of Cambridge, Cambridge, UK., Cornall RJ; MRC Human Immunology Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK; Nuffield Department of Medicine, University of Oxford, Oxford, UK. Electronic address: richard.cornall@ndm.ox.ac.uk., Klenerman D; Department of Chemistry, University of Cambridge, Cambridge, UK. Electronic address: dk10012@cam.ac.uk., Davis SJ; MRC Human Immunology Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK; Radcliffe Department of Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK. Electronic address: simon.davis@imm.ox.ac.uk.

المصدر: Immunity [Immunity] 2024 Feb 13; Vol. 57 (2), pp. 256-270.e10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 9432918 Publication Model: Print Cited Medium: Internet ISSN: 1097-4180 (Electronic) Linking ISSN: 10747613 NLM ISO Abbreviation: Immunity Subsets: MEDLINE

مواضيع طبية MeSH: Protein Tyrosine Phosphatases*/metabolism , Signal Transduction*, CD28 Antigens ; Receptors, Immunologic

المؤلفون: Barrie W; Department of Zoology, University of Cambridge, Cambridge, UK.; Department of Genetics, University of Cambridge, Cambridge, UK., Yang Y; Department of Statistical Sciences, School of Mathematics, University of Bristol, Bristol, UK.; MRC Integrative Epidemiology Unit, Population Health Sciences, University of Bristol, Bristol, UK., Irving-Pease EK; Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark., Attfield KE; Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK., Scorrano G; Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark., Jensen LT; Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark., Armen AP; Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK., Dimopoulos EA; Pathogen Genomics and Evolution Group, Department of Veterinary Medicine, University of Cambridge, Cambridge, UK., Stern A; Departments of Integrative Biology and Statistics, University of California, Berkeley, Berkeley, CA, USA., Refoyo-Martinez A; Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark., Pearson A; Department of Genetics, University of Cambridge, Cambridge, UK., Ramsøe A; Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark., Gaunitz C; Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark., Demeter F; Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.; Eco-anthropologie (EA), Muséum National d'Histoire Naturelle, CNRS, Université de Paris, Musée de l'Homme, Paris, France., Jørkov MLS; Laboratory of Biological Anthropology, Department of Forensic Medicine, University of Copenhagen, Copenhagen, Denmark., Møller SB; Ålborg Historiske Museum, Nordjyske Museer, Vestbjerg, Denmark., Springborg B; Ålborg Historiske Museum, Nordjyske Museer, Vestbjerg, Denmark., Klassen L; Museum Østdanmark-Djursland og Randers, Randers, Denmark., Hyldgård IM; Museum Østdanmark-Djursland og Randers, Randers, Denmark., Wickmann N; Museum Vestsjælland, Holbæk, Denmark., Vinner L; Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark., Korneliussen TS; Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark., Allentoft ME; Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.; Trace and Environmental DNA (TrEnD) Laboratory, School of Molecular and Life Sciences, Curtin University, Perth, Western Australia, Australia., Sikora M; Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark., Kristiansen K; Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.; Department of Historical Studies, University of Gothenburg, Gothenburg, Sweden., Rodriguez S; MRC Integrative Epidemiology Unit, Population Health Sciences, University of Bristol, Bristol, UK., Nielsen R; Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark.; Departments of Integrative Biology and Statistics, University of California, Berkeley, Berkeley, CA, USA., Iversen AKN; Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK. astrid.iversen@ndcn.ox.ac.uk.; Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK. astrid.iversen@ndcn.ox.ac.uk., Lawson DJ; Department of Statistical Sciences, School of Mathematics, University of Bristol, Bristol, UK. dan.lawson@bristol.ac.uk.; MRC Integrative Epidemiology Unit, Population Health Sciences, University of Bristol, Bristol, UK. dan.lawson@bristol.ac.uk., Fugger L; Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK. lars.fugger@ndcn.ox.ac.uk.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark. lars.fugger@ndcn.ox.ac.uk.; MRC Human Immunology Unit, John Radcliffe Hospital, University of Oxford, Oxford, UK. lars.fugger@ndcn.ox.ac.uk., Willerslev E; Department of Zoology, University of Cambridge, Cambridge, UK. ew482@cam.ac.uk.; Lundbeck Foundation GeoGenetics Centre, Globe Institute, University of Copenhagen, Copenhagen, Denmark. ew482@cam.ac.uk.; MARUM Center for Marine Environmental Sciences and Faculty of Geosciences, University of Bremen, Bremen, Germany. ew482@cam.ac.uk.

المصدر: Nature [Nature] 2024 Jan; Vol. 625 (7994), pp. 321-328. Date of Electronic Publication: 2024 Jan 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Genetic Predisposition to Disease*/history , Genome, Human* , Grassland* , Multiple Sclerosis*/genetics , Multiple Sclerosis*/history , Multiple Sclerosis*/immunology, Humans ; Datasets as Topic ; Diet/ethnology ; Diet/history ; Europe/ethnology ; Genetics, Medical ; History, 15th Century ; History, Ancient ; History, Medieval ; Human Migration/history ; Life Style/ethnology ; Life Style/history ; Neurodegenerative Diseases/genetics ; Neurodegenerative Diseases/history ; Neurodegenerative Diseases/immunology ; Population Density

المؤلفون: Jensen LT; Department of Clinical Medicine, Aarhus University Hospital, Aarhus 8200, Denmark., Attfield KE; Nuffield Department of Clinical Neurosciences, Oxford Centre for Neuroinflammation, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, UK., Feldmann M; Nuffield Department of Orthopaedics, Rheumatology and Musculoskeletal Sciences, The Kennedy Institute for Rheumatology, Botnar Research Institute, University of Oxford, Oxford OX3 7LD, UK., Fugger L; Department of Clinical Medicine, Aarhus University Hospital, Aarhus 8200, Denmark; Nuffield Department of Clinical Neurosciences, Oxford Centre for Neuroinflammation, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DU, UK; MRC Human Immunology Unit, John Radcliffe Hospital, University of Oxford, Oxford OX3 9DS, UK. Electronic address: lars.fugger@ndcn.ox.ac.uk.

المصدر: EBioMedicine [EBioMedicine] 2023 Nov; Vol. 97, pp. 104840. Date of Electronic Publication: 2023 Oct 18.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101647039 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2352-3964 (Electronic) Linking ISSN: 23523964 NLM ISO Abbreviation: EBioMedicine Subsets: MEDLINE

مواضيع طبية MeSH: Janus Kinase Inhibitors*/pharmacology , Janus Kinase Inhibitors*/therapeutic use , Autoimmune Diseases*/drug therapy , Psoriasis*/drug therapy, Humans ; TYK2 Kinase/genetics ; Cytokines ; Janus Kinase 1/genetics ; Janus Kinase 1/metabolism

المؤلفون: Kaur G; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Porter CBM; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Ashenberg O; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Lee J; Department of Biomedical Engineering, School of Biomedical Engineering and Imaging Sciences, King's College London, London, UK., Riesenfeld SJ; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Pritzker School of Molecular Engineering, University of Chicago, Chicago, IL, USA.; Department of Medicine, University of Chicago, Chicago, IL, USA., Hofree M; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Aggelakopoulou M; Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK., Subramanian A; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Kuttikkatte SB; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK., Attfield KE; Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK., Desel CAE; Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK.; University Department of Neurology, University Hospital Magdeburg, Magdeburg, Germany., Davies JL; Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK., Evans HG; Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK., Avraham-Davidi I; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Nguyen LT; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Dionne DA; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Neumann AE; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Jensen LT; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark., Barber TR; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK., Soilleux E; Department of Pathology, Tennis Court Rd, University of Cambridge, Cambridge, England., Carrington M; Basic Science Program, Frederick National Laboratory for Cancer Research in the Laboratory of Integrative Cancer Immunology, National Cancer Institute, Bethesda, MD, USA.; Ragon Institute of MGH, MIT, and Harvard, Cambridge, MA, USA., McVean G; Big Data Institute, Li Ka Shing Centre for Health Information and Discovery, University of Oxford, Oxford, UK., Rozenblatt-Rosen O; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Genentech, 1 DNA Way, South San Francisco, CA, USA., Regev A; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA. aregev@broadinstitute.org.; Massachusetts Institute of Technology, Department of Biology, Cambridge, MA, USA. aregev@broadinstitute.org.; Howard Hughes Medical Institute, Chevy Chase, MD, USA. aregev@broadinstitute.org.; Genentech, 1 DNA Way, South San Francisco, CA, USA. aregev@broadinstitute.org., Fugger L; MRC Human Immunology Unit, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK. lars.fugger@ndcn.ox.ac.uk.; Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, MRC Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK. lars.fugger@ndcn.ox.ac.uk.; Department of Clinical Medicine, Aarhus University Hospital, Aarhus, Denmark. lars.fugger@ndcn.ox.ac.uk.

المصدر: Nature communications [Nat Commun] 2022 Jul 29; Vol. 13 (1), pp. 4398. Date of Electronic Publication: 2022 Jul 29.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Fetal Growth Retardation*/genetics , Fetal Growth Retardation*/metabolism , Trophoblasts*/metabolism, Animals ; Cell Communication/genetics ; Female ; Fetus/metabolism ; HLA-C Antigens/genetics ; HLA-C Antigens/metabolism ; Mice ; Pregnancy

المؤلفون: Kaufmann M; Institut für Neuroimmunologie und Multiple Sklerose, Zentrum für Molekulare Neurobiologie Hamburg, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.; Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK., Schaupp AL; Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK., Sun R; Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK.; Proteomics Program, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark.; Department of Neurosurgery, Queen Elizabeth Hospital, Birmingham, UK., Coscia F; Proteomics Program, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark.; Spatial Proteomics Group, Max Delbrück Center for Molecular Medicine in the Helmholtz Association, Berlin, Germany., Dendrou CA; Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK.; Nuffield Department of Medicine, Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK., Cortes A; Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK., Kaur G; Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK.; MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK.; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Evans HG; Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK., Mollbrink A; Department of Gene Technology, KTH Royal Institute of Technology, Science for Life Laboratory, Solna, Sweden., Navarro JF; Department of Gene Technology, KTH Royal Institute of Technology, Science for Life Laboratory, Solna, Sweden., Sonner JK; Institut für Neuroimmunologie und Multiple Sklerose, Zentrum für Molekulare Neurobiologie Hamburg, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany., Mayer C; Institut für Neuroimmunologie und Multiple Sklerose, Zentrum für Molekulare Neurobiologie Hamburg, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany., DeLuca GC; Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, Oxford, UK., Lundeberg J; Department of Gene Technology, KTH Royal Institute of Technology, Science for Life Laboratory, Solna, Sweden., Matthews PM; Department of Brain Sciences, Imperial College London, London, UK.; UK Dementia Research Institute, Imperial College London, London, UK., Attfield KE; Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK., Friese MA; Institut für Neuroimmunologie und Multiple Sklerose, Zentrum für Molekulare Neurobiologie Hamburg, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany., Mann M; Proteomics Program, Novo Nordisk Foundation Center for Protein Research, University of Copenhagen, Copenhagen, Denmark.; Department of Proteomics and Signal Transduction, Max Planck Institute of Biochemistry, Martinsried, Germany., Fugger L; Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK. lars.fugger@imm.ox.ac.uk.; MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK. lars.fugger@imm.ox.ac.uk.

المصدر: Nature neuroscience [Nat Neurosci] 2022 Jul; Vol. 25 (7), pp. 944-955. Date of Electronic Publication: 2022 Jun 20.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 9809671 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1726 (Electronic) Linking ISSN: 10976256 NLM ISO Abbreviation: Nat Neurosci Subsets: MEDLINE

مواضيع طبية MeSH: Central Nervous System Diseases*/complications , Multiple Sclerosis*/pathology, Disease Progression ; Humans ; Neurons/metabolism ; Proteomics

المؤلفون: Kaufmann M; Institut für Neuroimmunologie und Multiple Sklerose, Zentrum für Molekulare Neurobiologie Hamburg, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany., Evans H; Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK., Schaupp AL; Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK., Engler JB; Institut für Neuroimmunologie und Multiple Sklerose, Zentrum für Molekulare Neurobiologie Hamburg, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany., Kaur G; Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK.; MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK., Willing A; Institut für Neuroimmunologie und Multiple Sklerose, Zentrum für Molekulare Neurobiologie Hamburg, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany., Kursawe N; Institut für Neuroimmunologie und Multiple Sklerose, Zentrum für Molekulare Neurobiologie Hamburg, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany., Schubert C; Institut für Neuroimmunologie und Multiple Sklerose, Zentrum für Molekulare Neurobiologie Hamburg, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany., Attfield KE; Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK., Fugger L; Oxford Centre for Neuroinflammation, Nuffield Department of Clinical Neurosciences, John Radcliffe Hospital, University of Oxford, Oxford, UK.; MRC Human Immunology Unit, Weatherall Institute of Molecular Medicine, John Radcliffe Hospital, University of Oxford, Oxford, UK., Friese MA; Institut für Neuroimmunologie und Multiple Sklerose, Zentrum für Molekulare Neurobiologie Hamburg, Universitätsklinikum Hamburg-Eppendorf, Hamburg, Germany.

المصدر: Med (New York, N.Y.) [Med] 2021 Mar 12; Vol. 2 (3), pp. 296-312.e8.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101769215 Publication Model: Print Cited Medium: Internet ISSN: 2666-6340 (Electronic) Linking ISSN: 26666340 NLM ISO Abbreviation: Med

مواضيع طبية MeSH: Multiple Sclerosis*/drug therapy , Multiple Sclerosis, Chronic Progressive*/drug therapy , Multiple Sclerosis, Relapsing-Remitting*/drug therapy, Central Nervous System/pathology ; Humans ; Natalizumab/therapeutic use ; T-Lymphocytes/pathology