المؤلفون: Whitson, RJ, Lee, A, Urman, NM, Mirza, A, Yao, CY, Brown, AS, Li, JR, Shankar, G, Fry, MA, Atwood, SX, Lee, EY, Hollmig, ST, Aasi, SZ, Sarin, KY, Scott, MP, Epstein, EH, Tang, JY, Oro, AE

المصدر: Whitson, RJ; Lee, A; Urman, NM; Mirza, A; Yao, CY; Brown, AS; et al.(2018). Noncanonical hedgehog pathway activation through SRF-MKL1 promotes drug resistance in basal cell carcinomas. Nature Medicine, 24(3), 271-281. doi: 10.1038/nm.4476. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/8hs9c3sv

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=od_______325::93553ba47d1b5fc46da3b0f02f345fa5
http://www.escholarship.org/uc/item/8hs9c3sv

المؤلفون: Long GR; Department of Developmental and Cell Biology, School of Biological Sciences, University of California, Irvine, Irvine, California, USA., Kurdian AI; Department of Developmental and Cell Biology, School of Biological Sciences, University of California, Irvine, Irvine, California, USA., Atwood SX; Department of Developmental and Cell Biology, School of Biological Sciences, University of California, Irvine, Irvine, California, USA; Department of Dermatology, School of Medicine, University of California, Irvine, Irvine, California, USA; Chao Family Comprehensive Cancer Center, University of California, Irvine, Irvine, California, USA. Electronic address: satwood@uci.edu.

المصدر: The Journal of investigative dermatology [J Invest Dermatol] 2024 Jun; Vol. 144 (6), pp. 1181-1183. Date of Electronic Publication: 2024 Feb 22.

نوع المنشور: Letter; Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 0426720 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-1747 (Electronic) Linking ISSN: 0022202X NLM ISO Abbreviation: J Invest Dermatol Subsets: MEDLINE

مواضيع طبية MeSH: Skin Neoplasms*/pathology , Skin Neoplasms*/genetics , Carcinoma, Basosquamous*/pathology , Carcinoma, Basosquamous*/genetics, Humans ; Male ; Female ; Multiomics

المؤلفون: Veniaminova NA; Department of Dermatology, Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA., Jia YY; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA 92697, USA., Hartigan AM; Department of Dermatology, Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA., Huyge TJ; Department of Dermatology, Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA., Tsai SY; Department of Dermatology, Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA., Grachtchouk M; Department of Dermatology, Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA., Nakagawa S; Department of Pathology, University of Michigan, Ann Arbor, MI 48109, USA; Department of Dermatology, Department of Cutaneous Immunology and Microbiology, Graduate School of Medicine, Osaka University, Suita, Osaka, 565-0871, Japan., Dlugosz AA; Department of Dermatology, Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA., Atwood SX; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA 92697, USA. Electronic address: satwood@uci.edu., Wong SY; Department of Dermatology, Department of Cell and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA. Electronic address: sunnyw@umich.edu.

المصدر: Cell reports [Cell Rep] 2023 Sep 26; Vol. 42 (9), pp. 113121. Date of Electronic Publication: 2023 Sep 19.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Sebaceous Glands* , Skin*, Cell Differentiation ; Hair Follicle ; Epithelial Cells

المؤلفون: Stabell AR; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA 92697, USA; NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine, Irvine, CA 92697, USA., Lee GE; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA 92697, USA., Jia Y; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA 92697, USA., Wong KN; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA 92697, USA; NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine, Irvine, CA 92697, USA., Wang S; Department of Mathematics, University of California, Irvine, Irvine, CA 92697, USA., Ling J; Department of Dermatology, University of California, San Diego, La Jolla, CA 92093, USA., Nguyen SD; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA 92697, USA., Sen GL; Department of Dermatology, University of California, San Diego, La Jolla, CA 92093, USA; Department of Cellular and Molecular Medicine, UCSD Stem Cell Program, University of California, San Diego, La Jolla, CA 92093, USA., Nie Q; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA 92697, USA; NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine, Irvine, CA 92697, USA; Department of Mathematics, University of California, Irvine, Irvine, CA 92697, USA; Center for Complex Biological Systems, Chao Family Comprehensive Cancer Center, University of California, Irvine, Irvine, CA 92697, USA., Atwood SX; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA 92697, USA; NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine, Irvine, CA 92697, USA; Center for Complex Biological Systems, Chao Family Comprehensive Cancer Center, University of California, Irvine, Irvine, CA 92697, USA; Department of Dermatology, University of California, Irvine, Irvine, CA 92697, USA. Electronic address: satwood@uci.edu.

المصدر: Cell reports [Cell Rep] 2023 May 30; Vol. 42 (5), pp. 112511. Date of Electronic Publication: 2023 May 16.

نوع المنشور: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Transcriptome*/genetics , Skin*/metabolism, Humans ; Keratinocytes/metabolism ; Epidermis/metabolism ; Cell Differentiation ; Organoids

المؤلفون: Cang Z; Department of Mathematics and Center for Research in Scientific Computation, North Carolina State University, Raleigh, NC, USA., Zhao Y; Department of Mathematics, The George Washington University, Washington, DC, USA., Almet AA; Department of Mathematics, University of California, Irvine, Irvine, CA, USA.; The NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine, Irvine, CA, USA., Stabell A; The NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine, Irvine, CA, USA.; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA, USA., Ramos R; The NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine, Irvine, CA, USA.; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA, USA., Plikus MV; The NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine, Irvine, CA, USA.; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA, USA., Atwood SX; The NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine, Irvine, CA, USA.; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA, USA., Nie Q; Department of Mathematics, University of California, Irvine, Irvine, CA, USA. qnie@uci.edu.; The NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine, Irvine, CA, USA. qnie@uci.edu.; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA, USA. qnie@uci.edu.

المصدر: Nature methods [Nat Methods] 2023 Feb; Vol. 20 (2), pp. 218-228. Date of Electronic Publication: 2023 Jan 23.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101215604 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1548-7105 (Electronic) Linking ISSN: 15487091 NLM ISO Abbreviation: Nat Methods Subsets: MEDLINE

مواضيع طبية MeSH: Transcriptome* , Cell Communication*/genetics, Humans ; Gene Expression Profiling ; Signal Transduction ; Computer Simulation ; Single-Cell Analysis

المؤلفون: Singha MK; Department of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, California 92697, United States., Zimak J; Department of Pharmaceutical Sciences, University of California, Irvine, Irvine, California 92697, United States., Levine SR; Department of Pharmaceutical Sciences, University of California, Irvine, Irvine, California 92697, United States., Dai N; New England Biolabs, Beverly, Massachusetts 01915, United States., Hong C; Department of Cell and Developmental Biology, University of California, Irvine, Irvine, California 92697, United States., Anaraki C; Department of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, California 92697, United States., Gupta M; Department of Chemistry, University of California, Irvine, Irvine, California 92697, United States., Halbrook CJ; Department of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, California 92697, United States., Atwood SX; Department of Cell and Developmental Biology, University of California, Irvine, Irvine, California 92697, United States., Spitale RC; Department of Molecular Biology and Biochemistry, University of California, Irvine, Irvine, California 92697, United States.; Department of Pharmaceutical Sciences, University of California, Irvine, Irvine, California 92697, United States.; Department of Chemistry, University of California, Irvine, Irvine, California 92697, United States.

المصدر: Biochemistry [Biochemistry] 2022 Dec 06; Vol. 61 (23), pp. 2638-2642. Date of Electronic Publication: 2022 Nov 16.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4995 (Electronic) Linking ISSN: 00062960 NLM ISO Abbreviation: Biochemistry Subsets: MEDLINE

مواضيع طبية MeSH: RNA*/chemistry , Tandem Mass Spectrometry*, Animals ; Mice ; Humans ; Chromatography, Liquid ; Gene Expression Profiling

المؤلفون: Bardwell AJ; Department of Developmental and Cell Biology, University of California, Irvine, CA, USA., Wu B; Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, CA, USA., Sarin KY; Department of Dermatology, Stanford University School of Medicine, Stanford, CA, USA., Waterman ML; Department of Microbiology and Molecular Genetics, School of Medicine, University of California, Irvine, CA, USA., Atwood SX; Department of Developmental and Cell Biology, University of California, Irvine, CA, USA., Bardwell L; Department of Developmental and Cell Biology, University of California, Irvine, CA, USA bardwell@uci.edu.

المصدر: Life science alliance [Life Sci Alliance] 2022 Jul 13; Vol. 5 (11). Date of Electronic Publication: 2022 Jul 13 (Print Publication: 2022).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Life Science Alliance, LLC Country of Publication: United States NLM ID: 101728869 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 2575-1077 (Electronic) Linking ISSN: 25751077 NLM ISO Abbreviation: Life Sci Alliance Subsets: MEDLINE

مواضيع طبية MeSH: Mitogen-Activated Protein Kinase 1* , Repressor Proteins* , Zinc Finger Protein GLI1*/antagonists & inhibitors , Zinc Finger Protein GLI1*/genetics , Zinc Finger Protein GLI1*/metabolism, Animals ; Binding Sites ; Cells, Cultured ; Conserved Sequence ; Hedgehog Proteins/metabolism ; Humans ; MAP Kinase Signaling System ; Mutation ; Neoplasms/genetics ; Neoplasms/metabolism ; Neoplasms/pathology ; Phosphorylation ; Protein Binding

المؤلفون: Guerrero-Juarez CF; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA 92697, USA.; Department of Mathematics, University of California, Irvine, Irvine, CA 92697, USA.; NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine, Irvine, CA 92697, USA.; Center for Complex Biological Systems, University of California, Irvine, Irvine, CA 92697, USA., Lee GH; Department of Dermatology, Stanford University School of Medicine, Stanford, CA 94305, USA., Liu Y; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA 92697, USA.; NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine, Irvine, CA 92697, USA., Wang S; Department of Mathematics, University of California, Irvine, Irvine, CA 92697, USA.; NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine, Irvine, CA 92697, USA., Karikomi M; Department of Mathematics, University of California, Irvine, Irvine, CA 92697, USA., Sha Y; Department of Mathematics, University of California, Irvine, Irvine, CA 92697, USA., Chow RY; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA 92697, USA., Nguyen TTL; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA 92697, USA., Iglesias VS; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA 92697, USA., Aasi S; Department of Dermatology, Stanford University School of Medicine, Stanford, CA 94305, USA., Drummond ML; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA 92697, USA., Nie Q; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA 92697, USA.; Department of Mathematics, University of California, Irvine, Irvine, CA 92697, USA.; NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine, Irvine, CA 92697, USA.; Center for Complex Biological Systems, University of California, Irvine, Irvine, CA 92697, USA., Sarin K; Department of Dermatology, Stanford University School of Medicine, Stanford, CA 94305, USA., Atwood SX; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA 92697, USA.; NSF-Simons Center for Multiscale Cell Fate Research, University of California, Irvine, Irvine, CA 92697, USA.; Center for Complex Biological Systems, University of California, Irvine, Irvine, CA 92697, USA.; Department of Dermatology, University of California, Irvine, Irvine, CA 92697, USA.; Chao Family Comprehensive Cancer Center, University of California, Irvine, Irvine, CA 92697, USA.

المصدر: Science advances [Sci Adv] 2022 Jun 10; Vol. 8 (23), pp. eabm7981. Date of Electronic Publication: 2022 Jun 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Basal Cell*/drug therapy , Carcinoma, Basal Cell*/genetics , Carcinoma, Basal Cell*/metabolism , Skin Neoplasms*/genetics , Skin Neoplasms*/pathology, Animals ; Ecosystem ; Hedgehog Proteins ; Humans ; Mice ; Single-Cell Analysis ; Tumor Microenvironment

المؤلفون: Beasley S; Department of Pharmaceutical Sciences, University of California─Irvine, Irvine, California 92697, United States., Vandewalle A; Department of Pharmaceutical Sciences, University of California─Irvine, Irvine, California 92697, United States., Singha M; Department of Pharmaceutical Sciences, University of California─Irvine, Irvine, California 92697, United States., Nguyen K; Department of Pharmaceutical Sciences, University of California─Irvine, Irvine, California 92697, United States., England W; Department of Pharmaceutical Sciences, University of California─Irvine, Irvine, California 92697, United States., Tarapore E; Department of Developmental & Cellular Biology, University of California─Irvine, Irvine, California 92697, United States., Dai N; New England Biolabs, 240 County Road, Ipswich, Massachusetts 01938, United States., Corrêa IR Jr; New England Biolabs, 240 County Road, Ipswich, Massachusetts 01938, United States., Atwood SX; Department of Developmental & Cellular Biology, University of California─Irvine, Irvine, California 92697, United States., Spitale RC; Department of Pharmaceutical Sciences, University of California─Irvine, Irvine, California 92697, United States.; Department of Chemistry, University of California─Irvine, Irvine, California 92697, United States.

المصدر: Journal of the American Chemical Society [J Am Chem Soc] 2022 Apr 27; Vol. 144 (16), pp. 7085-7088. Date of Electronic Publication: 2022 Apr 13.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE

مواضيع طبية MeSH: Neoplasms* , RNA*/metabolism, Nucleosides/metabolism

المؤلفون: Chow RY; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA, United States., Jeon US; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA, United States., Levee TM; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA, United States., Kaur G; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA, United States., Cedeno DP; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA, United States., Doan LT; Department of Dermatology, University of California, Irvine, Irvine, CA, United States., Atwood SX; Department of Developmental and Cell Biology, University of California, Irvine, Irvine, CA, United States.; Department of Dermatology, University of California, Irvine, Irvine, CA, United States.; Chao Family Comprehensive Cancer Center, University of California, Irvine, Irvine, CA, United States.

المصدر: Frontiers in oncology [Front Oncol] 2021 Jun 29; Vol. 11, pp. 668247. Date of Electronic Publication: 2021 Jun 29 (Print Publication: 2021).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101568867 Publication Model: eCollection Cited Medium: Print ISSN: 2234-943X (Print) Linking ISSN: 2234943X NLM ISO Abbreviation: Front Oncol Subsets: PubMed not MEDLINE