المؤلفون: Narmada BC; Laboratory of Precision Medicine and Cancer Evolution, Genome Institute of Singapore, Agency for Science, Technology and Research (A∗STAR), 60 Biopolis St., #02-01 Genome, Singapore 138672; Experimental Drug Development Centre, A∗STAR, 10 Biopolis Way, Chromos, Singapore 138670, Singapore., Khakpoor A; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Shirgaonkar N; Laboratory of Precision Medicine and Cancer Evolution, Genome Institute of Singapore, Agency for Science, Technology and Research (A∗STAR), 60 Biopolis St., #02-01 Genome, Singapore 138672., Narayanan S; Institute of Molecular and Cell Biology, A∗STAR, 61 Biopolis Drive, Proteos, Singapore, 138673, Singapore., Aw PPK; Laboratory of Precision Medicine and Cancer Evolution, Genome Institute of Singapore, Agency for Science, Technology and Research (A∗STAR), 60 Biopolis St., #02-01 Genome, Singapore 138672., Singh M; Bioinformatics Institute, A∗STAR, 30 Biopolis Street, Matrix, Singapore 138671, Singapore., Ong KH; Bioinformatics Institute, A∗STAR, 30 Biopolis Street, Matrix, Singapore 138671, Singapore., Owino CO; Laboratory of Precision Medicine and Cancer Evolution, Genome Institute of Singapore, Agency for Science, Technology and Research (A∗STAR), 60 Biopolis St., #02-01 Genome, Singapore 138672; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Ng JWT; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Yew HC; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Binte Mohamed Nasir NS; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Au VB; Institute of Molecular and Cell Biology, A∗STAR, 61 Biopolis Drive, Proteos, Singapore, 138673, Singapore., Sng R; Institute of Molecular and Cell Biology, A∗STAR, 61 Biopolis Drive, Proteos, Singapore, 138673, Singapore., Kaliaperumal N; Institute of Molecular and Cell Biology, A∗STAR, 61 Biopolis Drive, Proteos, Singapore, 138673, Singapore., Khine HHTW; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., di Tocco FC; Cancer Research Center of Lyon (CRCL), INSERM U1052, CNRS UMR5286, Lyon, France., Masayuki O; Translational Immunology Institute (TII), SingHealth-DukeNUS Academic Medical Centre, Singapore 169856, Singapore., Naikar S; Translational Immunology Institute (TII), SingHealth-DukeNUS Academic Medical Centre, Singapore 169856, Singapore., Ng HX; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Chia SL; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Seah CXY; Department of Medicine, National University Hospital, Singapore., Alnawaz MH; Department of Medicine, National University Hospital, Singapore., Wai CLY; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Tay AYL; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Mangat KS; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Chew V; Translational Immunology Institute (TII), SingHealth-DukeNUS Academic Medical Centre, Singapore 169856, Singapore., Yu W; Institute of Molecular and Cell Biology, A∗STAR, 61 Biopolis Drive, Proteos, Singapore, 138673, Singapore; Bioinformatics Institute, A∗STAR, 30 Biopolis Street, Matrix, Singapore 138671, Singapore., Connolly JE; Institute of Molecular and Cell Biology, A∗STAR, 61 Biopolis Drive, Proteos, Singapore, 138673, Singapore; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore; Institute of Biomedical Studies, Baylor University, Waco, TX, USA; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA., Periyasamy G; Experimental Drug Development Centre, A∗STAR, 10 Biopolis Way, Chromos, Singapore 138670, Singapore., Plissonnier ML; Cancer Research Center of Lyon (CRCL), INSERM U1052, CNRS UMR5286, Lyon, France., Levrero M; Cancer Research Center of Lyon (CRCL), INSERM U1052, CNRS UMR5286, Lyon, France; Department of Hepatology, Hôpital Croix-Rousse, Hospices Civils de Lyon, Lyon, France; University of Lyon Claude Bernard 1 (UCLB1), Lyon, France; Department of Medicine SCIAC and the Italian Institute of Technology (IIT) Center for Life Nanosciences (CLNS), University of Rome La Sapienza, Rome, Italy., Lim SG; Institute of Molecular and Cell Biology, A∗STAR, 61 Biopolis Drive, Proteos, Singapore, 138673, Singapore; Department of Medicine, National University Hospital, Singapore; Division of Gastroenterology and Hepatology, National University Hospital, National University Health System, Singapore. Electronic address: mdclimsg@nus.edu.sg., DasGupta R; Laboratory of Precision Medicine and Cancer Evolution, Genome Institute of Singapore, Agency for Science, Technology and Research (A∗STAR), 60 Biopolis St., #02-01 Genome, Singapore 138672. Electronic address: dasguptar@gis.a-star.edu.sg.

المصدر: Journal of hepatology [J Hepatol] 2024 Jul; Vol. 81 (1), pp. 42-61. Date of Electronic Publication: 2024 Feb 28.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 8503886 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1600-0641 (Electronic) Linking ISSN: 01688278 NLM ISO Abbreviation: J Hepatol Subsets: MEDLINE

مواضيع طبية MeSH: Hepatitis B, Chronic*/immunology , Hepatitis B, Chronic*/virology , Immunity, Innate*/immunology , Adaptive Immunity*/immunology , Single-Cell Analysis*/methods, Humans ; Hepatitis B virus/immunology ; Hepatitis B virus/genetics ; Male ; Female ; T-Lymphocytes, Cytotoxic/immunology ; Adult ; Liver/immunology ; Liver/pathology ; Hepatitis B Surface Antigens/immunology ; Middle Aged ; Killer Cells, Natural/immunology

المؤلفون: Prativadibhayankaram VS; Experimental Drug Development Centre, A*STAR Research Entities (ARES), Singapore, Singapore., Lee LS; National Centre for Infectious Diseases, Tan Tock Seng Hospital, 16 Jalan Tan Tock Seng, Singapore, 308442, Singapore., Lye D; National Centre for Infectious Diseases, Tan Tock Seng Hospital, 16 Jalan Tan Tock Seng, Singapore, 308442, Singapore.; Yong Loo Lin School of Medicine, Singapore, Singapore.; Lee Kong Chian School of Medicine, Singapore, Singapore., Xiaoying X; National Centre for Infectious Diseases, Tan Tock Seng Hospital, 16 Jalan Tan Tock Seng, Singapore, 308442, Singapore., Nellore R; Experimental Drug Development Centre, A*STAR Research Entities (ARES), Singapore, Singapore., Pendharkar V; Experimental Drug Development Centre, A*STAR Research Entities (ARES), Singapore, Singapore., Hentze H; Experimental Drug Development Centre, A*STAR Research Entities (ARES), Singapore, Singapore., Guan S; Hummingbird Bioscience, Singapore, Singapore., Ayers BJ; Hummingbird Bioscience, Singapore, Singapore., Seah SGK; Biological Defence Programme, DSO National Laboratories, Singapore, Singapore., Chye H; Biological Defence Programme, DSO National Laboratories, Singapore, Singapore., Talib NSN; Institute of Molecular and Cell Biology (IMCB), A*STAR Research Entities (ARES), Singapore, Singapore., Kaliaperumal N; Institute of Molecular and Cell Biology (IMCB), A*STAR Research Entities (ARES), Singapore, Singapore., Ong WY; Institute of Molecular and Cell Biology (IMCB), A*STAR Research Entities (ARES), Singapore, Singapore., Wong ZX; Institute of Molecular and Cell Biology (IMCB), A*STAR Research Entities (ARES), Singapore, Singapore., Au VB; Institute of Molecular and Cell Biology (IMCB), A*STAR Research Entities (ARES), Singapore, Singapore., Alok A; Institute of Molecular and Cell Biology (IMCB), A*STAR Research Entities (ARES), Singapore, Singapore., Connolly JE; Institute of Molecular and Cell Biology (IMCB), A*STAR Research Entities (ARES), Singapore, Singapore.; Institute of Biomedical Studies, Baylor University, Waco, TX, USA., Boyd-Kirkup JD; Hummingbird Bioscience, Singapore, Singapore., Ingram PJ; Hummingbird Bioscience, Singapore, Singapore., Hanson BJ; Hummingbird Bioscience, Singapore, Singapore., Ethirajulu K; Experimental Drug Development Centre, A*STAR Research Entities (ARES), Singapore, Singapore., O'Connell D; Experimental Drug Development Centre, A*STAR Research Entities (ARES), Singapore, Singapore., Chan CEZ; National Centre for Infectious Diseases, Tan Tock Seng Hospital, 16 Jalan Tan Tock Seng, Singapore, 308442, Singapore. conrad_ez_chan@ncid.sg.; Biological Defence Programme, DSO National Laboratories, Singapore, Singapore. conrad_ez_chan@ncid.sg.

المصدر: Infectious diseases and therapy [Infect Dis Ther] 2022 Oct; Vol. 11 (5), pp. 1999-2015. Date of Electronic Publication: 2022 Sep 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Adis Country of Publication: New Zealand NLM ID: 101634499 Publication Model: Print-Electronic Cited Medium: Print ISSN: 2193-8229 (Print) Linking ISSN: 21936382 NLM ISO Abbreviation: Infect Dis Ther Subsets: PubMed not MEDLINE

المؤلفون: Nickles E; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Life Sciences Institute, Immunology Programme, National University of Singapore, Singapore, Singapore.; Immunology Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Dharmadhikari B; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Life Sciences Institute, Immunology Programme, National University of Singapore, Singapore, Singapore.; Immunology Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Yating L; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; Life Sciences Institute, Immunology Programme, National University of Singapore, Singapore, Singapore.; Immunology Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Walsh RJ; Department of Haematology-Oncology, National University Cancer Institute, National University Health System, Singapore, Singapore., Koh LP; Department of Haematology-Oncology, National University Cancer Institute, National University Health System, Singapore, Singapore., Poon M; Department of Haematology-Oncology, National University Cancer Institute, National University Health System, Singapore, Singapore., Tan LK; Department of Haematology-Oncology, National University Cancer Institute, National University Health System, Singapore, Singapore., Wang LZ; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore., Ang Y; Department of Haematology-Oncology, National University Cancer Institute, National University Health System, Singapore, Singapore., Asokumaran Y; Department of Haematology-Oncology, National University Cancer Institute, National University Health System, Singapore, Singapore., Chong WQ; Department of Haematology-Oncology, National University Cancer Institute, National University Health System, Singapore, Singapore., Huang Y; Department of Haematology-Oncology, National University Cancer Institute, National University Health System, Singapore, Singapore., Loh KS; Department of Haematology-Oncology, National University Cancer Institute, National University Health System, Singapore, Singapore., Tay J, Soo R; Department of Haematology-Oncology, National University Cancer Institute, National University Health System, Singapore, Singapore., Koh M; Health Sciences Authority, Singapore, Singapore., Ho LP; Health Sciences Authority, Singapore, Singapore., Chan M; Health Sciences Authority, Singapore, Singapore., Niam M; Health Sciences Authority, Singapore, Singapore., Soh M; Health Sciences Authority, Singapore, Singapore., Luah YH; Health Sciences Authority, Singapore, Singapore., Lim CM; Department of Otolaryngology - Head and Neck Surgery, Singapore General Hospital, Singapore, Singapore., Kaliaperumal N; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore, Singapore., Au VB; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore, Singapore., Talib NBSN; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore, Singapore., Sng R; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore, Singapore., Connolly JE; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore, Singapore.; Parker Institute for Cancer Immunotherapy, San Francisco, CA, USA., Goh BC; Department of Haematology-Oncology, National University Cancer Institute, National University Health System, Singapore, Singapore. phcgbc@nus.edu.sg., Schwarz H; Department of Physiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. phssh@nus.edu.sg.; Life Sciences Institute, Immunology Programme, National University of Singapore, Singapore, Singapore. phssh@nus.edu.sg.; Immunology Translational Research Programme, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. phssh@nus.edu.sg.

المصدر: Cancer immunology, immunotherapy : CII [Cancer Immunol Immunother] 2022 Jun; Vol. 71 (6), pp. 1531-1543. Date of Electronic Publication: 2021 Oct 18.

نوع المنشور: Clinical Trial, Phase I; Journal Article

بيانات الدورية: Publisher: Springer Verlag Country of Publication: Germany NLM ID: 8605732 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1432-0851 (Electronic) Linking ISSN: 03407004 NLM ISO Abbreviation: Cancer Immunol Immunother Subsets: MEDLINE

مواضيع طبية MeSH: Epstein-Barr Virus Infections* , Nasopharyngeal Neoplasms*/therapy, 4-1BB Ligand/genetics ; Dendritic Cells ; Herpesvirus 4, Human ; Humans ; Nasopharyngeal Carcinoma/therapy

المؤلفون: Narayanan S; Translational Immunology Programme, Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology, and Research, Singapore (A*STAR) Research Entities (RE), 61 Biopolis Drive, Proteos, Singapore, 138673, Singapore., Au VB; Translational Immunology Programme, Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology, and Research, Singapore (A*STAR) Research Entities (RE), 61 Biopolis Drive, Proteos, Singapore, 138673, Singapore., Khakpoor A; Division of Gastroenterology and Hepatology, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Yan C; Division of Gastroenterology and Hepatology, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Ahl PJ; Translational Immunology Programme, Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology, and Research, Singapore (A*STAR) Research Entities (RE), 61 Biopolis Drive, Proteos, Singapore, 138673, Singapore., Kaliaperumal N; Translational Immunology Programme, Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology, and Research, Singapore (A*STAR) Research Entities (RE), 61 Biopolis Drive, Proteos, Singapore, 138673, Singapore., Lee B; Singapore Immunology Network, A*STAR REs, Singapore, Singapore., Xiang WW; IMCB, Tessa Therapeutics Pvt Ltd, Singapore, Singapore., Wang J; Division of Gastroenterology and Hepatology, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Lee C; Division of Gastroenterology and Hepatology, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Tay A; Division of Gastroenterology and Hepatology, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Lim SG; Translational Immunology Programme, Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology, and Research, Singapore (A*STAR) Research Entities (RE), 61 Biopolis Drive, Proteos, Singapore, 138673, Singapore.; Division of Gastroenterology and Hepatology, Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Connolly JE; Translational Immunology Programme, Institute of Molecular and Cell Biology (IMCB), Agency for Science, Technology, and Research, Singapore (A*STAR) Research Entities (RE), 61 Biopolis Drive, Proteos, Singapore, 138673, Singapore. jeconnolly@imcb.a-star.edu.sg.; Department of Microbiology and Immunology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. jeconnolly@imcb.a-star.edu.sg.; Institute of Biomedical Studies, Baylor University, Waco, TX, USA. jeconnolly@imcb.a-star.edu.sg.

المصدر: Scientific reports [Sci Rep] 2021 Apr 02; Vol. 11 (1), pp. 7455. Date of Electronic Publication: 2021 Apr 02.

نوع المنشور: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Chemokines/*blood , Cytokines/*blood , Hepatitis B Surface Antigens/*immunology , Hepatitis B, Chronic/*drug therapy , Hepatitis B, Chronic/*immunology, Bayes Theorem ; Hepatitis B, Chronic/blood ; Humans ; Interferon-alpha/therapeutic use ; Time Factors

المؤلفون: Hopkins R; Institute of Molecular and Cell Biology, A∗STAR, Singapore 138673, Singapore; Tessa Therapeutics, Singapore 038982, Singapore., Xiang W; Tessa Therapeutics, Singapore 038982, Singapore., Marlier D; Tessa Therapeutics, Singapore 038982, Singapore., Au VB; Institute of Molecular and Cell Biology, A∗STAR, Singapore 138673, Singapore., Ching Q; Institute of Molecular and Cell Biology, A∗STAR, Singapore 138673, Singapore., Wu LX; Institute of Molecular and Cell Biology, A∗STAR, Singapore 138673, Singapore., Guan R; Tessa Therapeutics, Singapore 038982, Singapore., Lee B; Singapore Immunology Network, Singapore 138648, Singapore., Chia WK; National Cancer Centre Singapore, Singapore 169610, Singapore., Wang WW; Tessa Therapeutics, Singapore 038982, Singapore; National Cancer Centre Singapore, Singapore 169610, Singapore., Wee J; National Cancer Centre Singapore, Singapore 169610, Singapore., Ng J; Tessa Therapeutics, Singapore 038982, Singapore; National Cancer Centre Singapore, Singapore 169610, Singapore., Cheong R; National Cancer Centre Singapore, Singapore 169610, Singapore., Han S; National Cancer Centre Singapore, Singapore 169610, Singapore., Chu A; National Cancer Centre Singapore, Singapore 169610, Singapore., Chee CL; National Cancer Centre Singapore, Singapore 169610, Singapore., Shuen T; National Cancer Centre Singapore, Singapore 169610, Singapore., Podinger M; Singapore Immunology Network, Singapore 138648, Singapore., Lezhava A; Genome Institute of Singapore, A∗STAR, Singapore 138672, Singapore., Toh HC; Institute of Molecular and Cell Biology, A∗STAR, Singapore 138673, Singapore; Tessa Therapeutics, Singapore 038982, Singapore; National Cancer Centre Singapore, Singapore 169610, Singapore. Electronic address: toh.han.chong@singhealth.com.sg., Connolly JE; Institute of Molecular and Cell Biology, A∗STAR, Singapore 138673, Singapore; Tessa Therapeutics, Singapore 038982, Singapore; Institute of Biomedical Studies, Baylor University, Waco, TX 76712, USA. Electronic address: jeconnolly@imcb.a-star.edu.sg.

المصدر: Molecular therapy : the journal of the American Society of Gene Therapy [Mol Ther] 2021 Feb 03; Vol. 29 (2), pp. 734-743. Date of Electronic Publication: 2020 Sep 30.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 100890581 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-0024 (Electronic) Linking ISSN: 15250016 NLM ISO Abbreviation: Mol Ther Subsets: MEDLINE

مواضيع طبية MeSH: Immunotherapy, Adoptive*/methods, Myeloid-Derived Suppressor Cells/*immunology , Nasopharyngeal Carcinoma/*immunology , Nasopharyngeal Carcinoma/*therapy , T-Lymphocytes/*immunology, Epstein-Barr Virus Infections/immunology ; Herpesvirus 4, Human/immunology ; Humans ; Myeloid-Derived Suppressor Cells/metabolism ; Nasopharyngeal Carcinoma/pathology ; T-Lymphocytes/metabolism ; T-Lymphocytes, Cytotoxic/immunology ; T-Lymphocytes, Cytotoxic/metabolism ; Treatment Failure ; Treatment Outcome

المؤلفون: Tan EE; Department of Paediatric Subspecialties, KK Women's and Children's Hospital, Singapore.; Duke-NUS Medical School, Singapore., Hopkins RA; Program in Translational Immunology, Institute of Molecular and Cell Biology, A*STAR, Singapore., Lim CK; Program in Translational Immunology, Institute of Molecular and Cell Biology, A*STAR, Singapore., Jamuar SS; Department of Paediatric Subspecialties, KK Women's and Children's Hospital, Singapore.; Duke-NUS Medical School, Singapore., Ong C; Duke-NUS Medical School, Singapore.; Department of Paediatrics and., Thoon KC; Duke-NUS Medical School, Singapore.; Department of Paediatrics and., Koh MJ; Duke-NUS Medical School, Singapore.; Dermatology Service, KK Women's and Children's Hospital, Singapore., Shin EM; Institute of Molecular and Cell Biology, A*STAR, Singapore.; Cancer Science Institute of Singapore, Singapore.; National University of Singapore, Singapore., Lian DW; Department of Paediatric Subspecialties, KK Women's and Children's Hospital, Singapore.; Duke-NUS Medical School, Singapore.; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Weerasooriya M; Department of Microbiology and Immunology and.; Immunology Programme, Life Sciences Institute, National University of Singapore, Singapore., Lee CZ; Singapore Immunology Network and., Soetedjo AAP; Institute of Molecular and Cell Biology, A*STAR, Singapore., Lim CS; Institute of Molecular and Cell Biology, A*STAR, Singapore., Au VB; Program in Translational Immunology, Institute of Molecular and Cell Biology, A*STAR, Singapore., Chua E; Program in Translational Immunology, Institute of Molecular and Cell Biology, A*STAR, Singapore., Lee HY; Institute of Molecular and Cell Biology, A*STAR, Singapore., Jones LA; Program in Translational Immunology, Institute of Molecular and Cell Biology, A*STAR, Singapore., James SS; Department of Microbiology and Immunology and.; Immunology Programme, Life Sciences Institute, National University of Singapore, Singapore., Kaliaperumal N; Program in Translational Immunology, Institute of Molecular and Cell Biology, A*STAR, Singapore., Kwok J; Program in Translational Immunology, Institute of Molecular and Cell Biology, A*STAR, Singapore., Tan ES; Duke-NUS Medical School, Singapore.; Department of Paediatrics and., Thomas B; Duke-NUS Medical School, Singapore.; Department of Paediatrics and., Wu LX; Program in Translational Immunology, Institute of Molecular and Cell Biology, A*STAR, Singapore., Ho L; Institute of Molecular and Cell Biology, A*STAR, Singapore., Fairhurst AM; Institute of Molecular and Cell Biology, A*STAR, Singapore., Ginhoux F; Singapore Immunology Network and., Teo AK; Institute of Molecular and Cell Biology, A*STAR, Singapore., Zhang YL; Department of Microbiology and Immunology and.; Immunology Programme, Life Sciences Institute, National University of Singapore, Singapore., Ong KH; Institute of Molecular and Cell Biology, A*STAR, Singapore., Yu W; Institute of Molecular and Cell Biology, A*STAR, Singapore., Venkatesh B; Institute of Molecular and Cell Biology, A*STAR, Singapore., Tergaonkar V; Department of Pathology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Laboratory of NF-κB Signaling, Institute of Molecular and Cell Biology, A*STAR, Singapore.; Centre for Cancer Biology, University of South Australia and SA Pathology, Adelaide, Australia.; Faculty of Health Sciences, University of Macau, Macau, China., Reversade B; Institute of Molecular and Cell Biology, A*STAR, Singapore.; Department of Medical Genetics, School of Medicine, Koç University, Istanbul, Turkey.; Department of Paediatrics, National University of Singapore, Singapore.; Institute of Medical Biology, A*STAR, Singapore., Chin KC; Program in Translational Immunology, Institute of Molecular and Cell Biology, A*STAR, Singapore.; Department of Physiology and., Tan AM; Singapore Immunology Network and., Liew WK; Duke-NUS Medical School, Singapore.; Department of Paediatrics and., Connolly JE; Program in Translational Immunology, Institute of Molecular and Cell Biology, A*STAR, Singapore.; Department of Paediatrics and.; Department of Microbiology and Immunity, National University of Singapore, Singapore.; Institute of Biomedical Studies, Baylor University Medical Center, Waco, Texas, USA.

المصدر: The Journal of clinical investigation [J Clin Invest] 2020 Nov 02; Vol. 130 (11), pp. 5817-5832.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

مواضيع طبية MeSH: Genes, Dominant* , Hematopoietic Stem Cell Transplantation* , Interleukin-1beta*/genetics , Interleukin-1beta*/immunology , Liver Diseases*/genetics , Liver Diseases*/immunology , Liver Diseases*/therapy , Mutation* , NF-KappaB Inhibitor alpha*/genetics , NF-KappaB Inhibitor alpha*/immunology , Severe Combined Immunodeficiency*/genetics , Severe Combined Immunodeficiency*/immunology , Severe Combined Immunodeficiency*/therapy, Allografts ; Animals ; Female ; HEK293 Cells ; Humans ; Male ; Mice ; Neutropenia/genetics ; Neutropenia/immunology ; Neutropenia/therapy ; Signal Transduction/genetics ; Signal Transduction/immunology

المؤلفون: Ngoi NY; Department of Haematology-Oncology, National University Cancer Institute, Singapore., Heong V; Department of Medical Oncology, Tan Tock Seng Hospital, Singapore., Ow S; Department of Haematology-Oncology, National University Cancer Institute, Singapore., Chay WY; Division of Medical Oncology, National Cancer Centre Singapore, Singapore., Kim HS; Department of Obstetrics and Gynecology, Seoul National University, Seoul, Republic of Korea., Choi CH; Department of Obstetrics and Gynecology, Samsung Medical Center, Seoul, Republic of Korea., Goss G; Box Hill Hospital, Box Hill, Victoria, Australia., Goh JC; Royal Brisbane and Women's Hospital, Herston, Queensland, Australia.; The University of Queensland, Saint Lucia, Queensland, Australia., Tai BC; Saw Swee Hock School of Public Health, National University of Singapore, Singapore.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Lim DG; Department of Pathology, National University Hospital, Singapore., Kaliaperumal N; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore., Au VB; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore., Connolly JE; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore.; Institute of Biomedical Studies, Baylor University, Waco, Texas, USA., Kim JW; Department of Obstetrics and Gynecology, Seoul National University, Seoul, Republic of Korea., Friedlander M; The Prince of Wales Hospital, Randwick, New South Wales, Australia.; Prince of Wales Clinical School University of New South Wales, Randwick, New South Wales, Australia., Kim K; Seoul National University Bundang Hospital, Seoul, Republic of Korea., Tan DS; Department of Haematology-Oncology, National University Cancer Institute, Singapore david_sp_tan@nuhs.edu.sg.; Yong Loo Lin School of Medicine, National University of Singapore, Singapore.; Cancer Science Institute Singapore, Singapore.

المصدر: International journal of gynecological cancer : official journal of the International Gynecological Cancer Society [Int J Gynecol Cancer] 2020 Aug; Vol. 30 (8), pp. 1239-1242. Date of Electronic Publication: 2020 Jun 25.

نوع المنشور: Clinical Trial Protocol; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BMJ Country of Publication: England NLM ID: 9111626 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1525-1438 (Electronic) Linking ISSN: 1048891X NLM ISO Abbreviation: Int J Gynecol Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Adenocarcinoma, Clear Cell*/diagnostic imaging , Adenocarcinoma, Clear Cell*/drug therapy , Antibodies, Monoclonal*/therapeutic use , Antineoplastic Agents*/therapeutic use , Immune Checkpoint Inhibitors*/therapeutic use , Neoplasm Recurrence, Local*/diagnostic imaging , Neoplasm Recurrence, Local*/drug therapy , Ovarian Neoplasms*/diagnostic imaging , Ovarian Neoplasms*/drug therapy, Female ; Humans ; Antineoplastic Agents, Immunological/therapeutic use ; Progression-Free Survival ; Response Evaluation Criteria in Solid Tumors ; Survival Rate ; Clinical Trials, Phase II as Topic ; Multicenter Studies as Topic ; Randomized Controlled Trials as Topic

المؤلفون: Ng PML; Singapore Immunology Network, Agency for Science, Technology and Research, S138648 Singapore., Kaliaperumal N; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, S138673 Singapore., Lee CY; Singapore Immunology Network, Agency for Science, Technology and Research, S138648 Singapore., Chin WJ; Singapore Immunology Network, Agency for Science, Technology and Research, S138648 Singapore.; School of Biological Science, Nanyang Technological University, S637551 Singapore., Tan HC; Singapore Immunology Network, Agency for Science, Technology and Research, S138648 Singapore., Au VB; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, S138673 Singapore., Goh AX; Singapore Immunology Network, Agency for Science, Technology and Research, S138648 Singapore., Tan QW; Singapore Immunology Network, Agency for Science, Technology and Research, S138648 Singapore.; School of Life Sciences and Chemical Technology, Ngee Ann Polytechnic, S599489 Singapore; and., Yeo DSG; Singapore Immunology Network, Agency for Science, Technology and Research, S138648 Singapore.; School of Life Sciences and Chemical Technology, Ngee Ann Polytechnic, S599489 Singapore; and., Connolly JE; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, S138673 Singapore; Wang_ChengI@immunol.a-star.edu.sg jeconnolly@imcb.a-star.edu.sg.; Institute of Biomedical Studies, Baylor University, Waco, TX 76712., Wang CI; Singapore Immunology Network, Agency for Science, Technology and Research, S138648 Singapore; Wang_ChengI@immunol.a-star.edu.sg jeconnolly@imcb.a-star.edu.sg.

المصدر: Journal of immunology (Baltimore, Md. : 1950) [J Immunol] 2019 Apr 15; Vol. 202 (8), pp. 2307-2319. Date of Electronic Publication: 2019 Feb 22.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association of Immunologists Country of Publication: United States NLM ID: 2985117R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1550-6606 (Electronic) Linking ISSN: 00221767 NLM ISO Abbreviation: J Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Antigen Presentation*, Dendritic Cells/*immunology , Monocytes/*immunology , Ribonucleoproteins/*immunology, CD8-Positive T-Lymphocytes/cytology ; CD8-Positive T-Lymphocytes/immunology ; Dendritic Cells/cytology ; Humans ; Immunoglobulin Fc Fragments/immunology ; Immunoglobulin G/immunology ; Monocytes/cytology ; Ribonucleoproteins/genetics

المؤلفون: Mac Aogáin M; 1 Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore., Tiew PY; 1 Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.; 2 Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore., Lim AYH; 3 Department of Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore., Low TB; 4 Department of Respiratory and Critical Care Medicine, Changi General Hospital, Singapore., Tan GL; 2 Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore., Hassan T; 5 Universiti Kebangsaan Malaysia, Kuala Lumpur, Malaysia., Ong TH; 2 Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore., Pang SL; 6 Department of Biological Sciences, National University of Singapore, Singapore.; 7 Institute of Systems Biology, Universiti Kebangsaan Malaysia, Bangi, Selangor, Malaysia., Lee ZY; 6 Department of Biological Sciences, National University of Singapore, Singapore., Gwee XW; 6 Department of Biological Sciences, National University of Singapore, Singapore., Martinus C; 6 Department of Biological Sciences, National University of Singapore, Singapore., Sio YY; 6 Department of Biological Sciences, National University of Singapore, Singapore., Matta SA; 6 Department of Biological Sciences, National University of Singapore, Singapore., Ong TC; 6 Department of Biological Sciences, National University of Singapore, Singapore., Tiong YS; 6 Department of Biological Sciences, National University of Singapore, Singapore., Wong KN; 6 Department of Biological Sciences, National University of Singapore, Singapore., Narayanan S; 8 Institute of Molecular and Cell Biology, A*STAR, Singapore., Au VB; 8 Institute of Molecular and Cell Biology, A*STAR, Singapore., Marlier D; 8 Institute of Molecular and Cell Biology, A*STAR, Singapore., Keir HR; 9 University of Dundee, Ninewells Hospital and Medical School, Dundee, Scotland; and., Tee A; 4 Department of Respiratory and Critical Care Medicine, Changi General Hospital, Singapore., Abisheganaden JA; 3 Department of Respiratory and Critical Care Medicine, Tan Tock Seng Hospital, Singapore., Koh MS; 2 Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore., Wang Y; 10 Department of Otolaryngology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore., Connolly JE; 8 Institute of Molecular and Cell Biology, A*STAR, Singapore., Chew FT; 6 Department of Biological Sciences, National University of Singapore, Singapore., Chalmers JD; 9 University of Dundee, Ninewells Hospital and Medical School, Dundee, Scotland; and., Chotirmall SH; 1 Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore.

المصدر: American journal of respiratory and critical care medicine [Am J Respir Crit Care Med] 2019 Apr 01; Vol. 199 (7), pp. 842-853.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Thoracic Society Country of Publication: United States NLM ID: 9421642 Publication Model: Print Cited Medium: Internet ISSN: 1535-4970 (Electronic) Linking ISSN: 1073449X NLM ISO Abbreviation: Am J Respir Crit Care Med Subsets: MEDLINE

مواضيع طبية MeSH: Aspergillus* , Pyroglyphidae*, Allergens/*adverse effects , Allergens/*immunology , Asthma/*etiology , Asthma/*immunology , Bronchiectasis/*complications , Bronchiectasis/*immunology, Adult ; Aged ; Aged, 80 and over ; Animals ; Cohort Studies ; Female ; Humans ; Hypersensitivity/immunology ; Immunization ; Male ; Middle Aged

المؤلفون: Zhong FL; From the Institute of Molecular and Cell Biology, A*STAR, Proteos, Singapore 138673, franklin.zhong@reversade.com.; the Institute of Medical Biology, A*STAR, Immunos, Singapore 138648.; the Skin Research Institute of Singapore, Immunos, Singapore 138648.; the Lee Kong Chian School of Medicine, Nanyang Technological University, Singapore 636921., Robinson K; the Institute of Medical Biology, A*STAR, Immunos, Singapore 138648.; the Skin Research Institute of Singapore, Immunos, Singapore 138648., Teo DET; From the Institute of Molecular and Cell Biology, A*STAR, Proteos, Singapore 138673.; the Institute of Medical Biology, A*STAR, Immunos, Singapore 138648.; the Skin Research Institute of Singapore, Immunos, Singapore 138648., Tan KY; From the Institute of Molecular and Cell Biology, A*STAR, Proteos, Singapore 138673., Lim C; From the Institute of Molecular and Cell Biology, A*STAR, Proteos, Singapore 138673., Harapas CR; the Inflammation Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia., Yu CH; the Inflammation Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia., Xie WH; the Institute of Medical Biology, A*STAR, Immunos, Singapore 138648., Sobota RM; From the Institute of Molecular and Cell Biology, A*STAR, Proteos, Singapore 138673., Au VB; From the Institute of Molecular and Cell Biology, A*STAR, Proteos, Singapore 138673., Hopkins R; From the Institute of Molecular and Cell Biology, A*STAR, Proteos, Singapore 138673., D'Osualdo A; Roche Pharma Research and Early Development, Roche Innovation Center Basel, F. Hoffmann-La Roche Ltd., 4070 Basel, Switzerland., Reed JC; the Sanford-Burnham-Prebys Medical Discovery Institute, La Jolla, California 92037., Connolly JE; From the Institute of Molecular and Cell Biology, A*STAR, Proteos, Singapore 138673.; the Institute of Biomedical Studies, Baylor University, Waco, Texas 76712.; the Department of Microbiology and Immunology, National University of Singapore, Singapore 117545., Masters SL; the Inflammation Division, Walter and Eliza Hall Institute of Medical Research, Parkville, Victoria 3052, Australia.; the Department of Medical Biology, University of Melbourne, Parkville, Victoria 3010 Australia., Reversade B; From the Institute of Molecular and Cell Biology, A*STAR, Proteos, Singapore 138673, bruno@reversade.com.; the Institute of Medical Biology, A*STAR, Immunos, Singapore 138648.; the Reproductive Biology Laboratory, Obstetrics and Gynaecology, Amsterdam UMC, 1105 AZ Amsterdam-Zuidoost, The Netherlands.; the Department of Paediatrics, National University of Singapore, Singapore 119228.; the Medical Genetics Department, Koç University School of Medicine, 34010 Istanbul, Turkey, and.

المصدر: The Journal of biological chemistry [J Biol Chem] 2018 Dec 07; Vol. 293 (49), pp. 18864-18878. Date of Electronic Publication: 2018 Oct 05.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Adaptor Proteins, Signal Transducing/*metabolism , Apoptosis Regulatory Proteins/*metabolism , Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/*metabolism , Inflammasomes/*metabolism, Adaptor Proteins, Signal Transducing/antagonists & inhibitors ; Adaptor Proteins, Signal Transducing/genetics ; Apoptosis Regulatory Proteins/antagonists & inhibitors ; Apoptosis Regulatory Proteins/genetics ; Boronic Acids/pharmacology ; CARD Signaling Adaptor Proteins/metabolism ; Dipeptides/pharmacology ; Dipeptidyl-Peptidases and Tripeptidyl-Peptidases/antagonists & inhibitors ; Enzyme Inhibitors/pharmacology ; Germ-Line Mutation ; HEK293 Cells ; Humans ; Inflammation/genetics ; Mutation, Missense ; NLR Proteins ; Neoplasm Proteins/metabolism ; Protein Binding ; Protein Domains