المؤلفون: Auger SA; Department of Chemistry, University of Minnesota─Twin Cities, 207 Pleasant Street, Minneapolis, Minnesota 55455, United States., Venkatachalapathy S; Department of Chemistry, University of Minnesota─Twin Cities, 207 Pleasant Street, Minneapolis, Minnesota 55455, United States., Suazo KFG; Department of Chemistry, University of Minnesota─Twin Cities, 207 Pleasant Street, Minneapolis, Minnesota 55455, United States., Wang Y; Department of Chemistry, University of Minnesota─Twin Cities, 207 Pleasant Street, Minneapolis, Minnesota 55455, United States., Sarkis AW; Department of Chemistry, University of Minnesota─Twin Cities, 207 Pleasant Street, Minneapolis, Minnesota 55455, United States., Bernhagen K; Department of Chemistry, University of Minnesota─Twin Cities, 207 Pleasant Street, Minneapolis, Minnesota 55455, United States., Justyna K; Department of Chemistry, University of Minnesota─Twin Cities, 207 Pleasant Street, Minneapolis, Minnesota 55455, United States., Schaefer JV; Department of Biochemistry, University of Zurich, Zurich CH-8057, Switzerland., Wollack JW; Department of Chemistry and Biochemistry, St. Catherine University, 2004 Randolph Avenue, St. Paul, Minnesota 55105, United States., Plückthun A; Department of Biochemistry, University of Zurich, Zurich CH-8057, Switzerland., Li L; Department of Experimental and Clinical Pharmacology, University of Minnesota─Twin Cities, 2001 6th Street SE, Minneapolis, Minnesota 55455, United States., Distefano MD; Department of Chemistry, University of Minnesota─Twin Cities, 207 Pleasant Street, Minneapolis, Minnesota 55455, United States.

المصدر: Bioconjugate chemistry [Bioconjug Chem] 2024 Jul 17; Vol. 35 (7), pp. 922-933. Date of Electronic Publication: 2024 Apr 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9010319 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4812 (Electronic) Linking ISSN: 10431802 NLM ISO Abbreviation: Bioconjug Chem Subsets: MEDLINE

مواضيع طبية MeSH: Norbornanes*/chemistry , Click Chemistry* , Farnesyltranstransferase*/metabolism , Protein Prenylation*, Humans ; Animals

المؤلفون: Suazo KF; Department of Chemistry, University of Minnesota, Minneapolis, MN 55455, USA. Electronic address: suazo003@umn.edu., Mishra V; Center for Motor Neuron Biology and Diseases, Department of Neurology. Columbia University Irving Medical Center. New York, NY 10032, USA; Department of Pathology & Cell Biology. Columbia University Irving Medical Center. New York, NY 10032, USA. Electronic address: vartikarmishra@gmail.com., Maity S; Department of Chemistry, University of Minnesota, Minneapolis, MN 55455, USA., Auger SA; Department of Chemistry, University of Minnesota, Minneapolis, MN 55455, USA. Electronic address: auger054@umn.edu., Justyna K; Department of Chemistry, University of Minnesota, Minneapolis, MN 55455, USA. Electronic address: kjustyna@umn.edu., Petre AM; Department of Chemistry, University of Minnesota, Minneapolis, MN 55455, USA. Electronic address: petre096@umn.edu., Ottoboni L; Department of Pathophysiology and Transplantation, Dino Ferrari Center, Università degli Studi di Milano, Milan, Italy. Electronic address: linda.ottoboni@unimi.it., Ongaro J; Neurology Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Corti SP; Department of Pathophysiology and Transplantation, Dino Ferrari Center, Università degli Studi di Milano, Milan, Italy; Neurology Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy; Neuromuscular and Rare Diseases Unit, Department of Neuroscience, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy. Electronic address: stefania.corti@unimi.it., Lotti F; Center for Motor Neuron Biology and Diseases, Department of Neurology. Columbia University Irving Medical Center. New York, NY 10032, USA; Department of Pathology & Cell Biology. Columbia University Irving Medical Center. New York, NY 10032, USA. Electronic address: fl2219@cumc.columbia.edu., Przedborski S; Center for Motor Neuron Biology and Diseases, Department of Neurology. Columbia University Irving Medical Center. New York, NY 10032, USA; Department of Pathology & Cell Biology. Columbia University Irving Medical Center. New York, NY 10032, USA; Department of Neuroscience, Pathology, and Cell Biology, Columbia University Irving Medical Center, New York, NY 10032, USA. Electronic address: sp30@cumc.columbia.edu., Distefano MD; Department of Chemistry, University of Minnesota, Minneapolis, MN 55455, USA. Electronic address: diste001@umn.edu.

المصدر: Bioorganic chemistry [Bioorg Chem] 2024 Jun; Vol. 147, pp. 107365. Date of Electronic Publication: 2024 Apr 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

مواضيع طبية MeSH: Astrocytes*/metabolism , Astrocytes*/cytology , Protein Prenylation* , Alkynes*/chemistry , Alkynes*/chemical synthesis , Motor Neurons*/metabolism , Motor Neurons*/cytology, Animals ; Terpenes/chemistry ; Terpenes/chemical synthesis ; Terpenes/metabolism ; Mice ; Molecular Structure ; Cells, Cultured

المؤلفون: Suazo KF; Department of Chemistry, University of Minnesota, Minneapolis, MN USA 55455., Mishra V; Center for Motor Neuron Biology and Diseases, Department of Neurology. Columbia University Irving Medical Center. New York, NY 10032.; Department of Pathology & Cell Biology. Columbia University Irving Medical Center. New York, NY 10032., Maity S; Department of Chemistry, University of Minnesota, Minneapolis, MN USA 55455., Auger SA; Department of Chemistry, University of Minnesota, Minneapolis, MN USA 55455., Justyna K; Department of Chemistry, University of Minnesota, Minneapolis, MN USA 55455., Petre A; Department of Chemistry, University of Minnesota, Minneapolis, MN USA 55455., Ottoboni L; Department of Pathophysiology and Transplantation, Dino Ferrari Center, Università degli Studi di Milano, Milan, Italy., Ongaro J; Neurology Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Corti SP; Department of Pathophysiology and Transplantation, Dino Ferrari Center, Università degli Studi di Milano, Milan, Italy.; Neurology Unit, Foundation IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy.; Neuromuscular and Rare Diseases Unit, Department of Neuroscience, Fondazione IRCCS Ca' Granda Ospedale Maggiore Policlinico, Milan, Italy., Lotti F; Center for Motor Neuron Biology and Diseases, Department of Neurology. Columbia University Irving Medical Center. New York, NY 10032.; Department of Pathology & Cell Biology. Columbia University Irving Medical Center. New York, NY 10032., Przedborski S; Center for Motor Neuron Biology and Diseases, Department of Neurology. Columbia University Irving Medical Center. New York, NY 10032.; Department of Pathology & Cell Biology. Columbia University Irving Medical Center. New York, NY 10032.; Department of Neuroscience, Pathology, and Cell Biology, Columbia University Irving Medical Center, New York, NY 10032., Distefano MD; Department of Chemistry, University of Minnesota, Minneapolis, MN USA 55455.

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2024 Mar 06. Date of Electronic Publication: 2024 Mar 06.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Puthenveetil R; Section on Structural and Chemical Biology, Neurosciences and Cellular and Structural Biology Division, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20817, United States., Auger SA; Department of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States., Gómez-Navarro N; Section on Structural and Chemical Biology, Neurosciences and Cellular and Structural Biology Division, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20817, United States., Rana MS; Section on Structural and Chemical Biology, Neurosciences and Cellular and Structural Biology Division, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20817, United States., Das R; Department of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States., Healy LB; Section on Structural and Chemical Biology, Neurosciences and Cellular and Structural Biology Division, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20817, United States., Suazo KF; Department of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States., Shi ZD; The Chemistry and Synthesis Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Rockville, Maryland 20850, United States., Swenson RE; The Chemistry and Synthesis Center, National Heart, Lung, and Blood Institute, National Institutes of Health, Rockville, Maryland 20850, United States., Distefano MD; Department of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States., Banerjee A; Section on Structural and Chemical Biology, Neurosciences and Cellular and Structural Biology Division, Eunice Kennedy Shriver National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, Maryland 20817, United States.

المصدر: Journal of the American Chemical Society [J Am Chem Soc] 2023 Oct 18; Vol. 145 (41), pp. 22287-22292. Date of Electronic Publication: 2023 Sep 29.

نوع المنشور: Journal Article; Research Support, N.I.H., Intramural; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE

مواضيع طبية MeSH: Acyltransferases*/metabolism , COVID-19*, Humans ; Substrate Specificity ; SARS-CoV-2/metabolism ; Proteins/metabolism ; Lipoylation

المؤلفون: Suazo KF; Department of Chemistry, University of Minnesota Minneapolis MN 55455 USA suazo003@umn.edu auger054@umn.edu petre096@umn.edu diste001@umn.edu., Bělíček J; Department of Experimental Biology, Faculty of Science, Palacký University CZ-78371 Czech Republic jakub.belicek01@upol.cz david.kopecny@upol.cz., Schey GL; Department of Medicinal Chemistry, University of Minnesota Minneapolis MN 55455 USA schey013@umn.edu., Auger SA; Department of Chemistry, University of Minnesota Minneapolis MN 55455 USA suazo003@umn.edu auger054@umn.edu petre096@umn.edu diste001@umn.edu., Petre AM; Department of Chemistry, University of Minnesota Minneapolis MN 55455 USA suazo003@umn.edu auger054@umn.edu petre096@umn.edu diste001@umn.edu., Li L; Department of Experimental and Clinical Pharmacology, University of Minnesota Minneapolis MN 55455 USA lil@umn.edu., Błażewska KM; Institute of Organic Chemistry, Faculty of Chemistry, Lodz University of Technology Łódź Poland katarzyna.blazewska@p.lodz.pl., Kopečný D; Department of Experimental Biology, Faculty of Science, Palacký University CZ-78371 Czech Republic jakub.belicek01@upol.cz david.kopecny@upol.cz., Distefano MD; Department of Chemistry, University of Minnesota Minneapolis MN 55455 USA suazo003@umn.edu auger054@umn.edu petre096@umn.edu diste001@umn.edu.

المصدر: RSC chemical biology [RSC Chem Biol] 2023 Aug 30; Vol. 4 (11), pp. 913-925. Date of Electronic Publication: 2023 Aug 30 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101768727 Publication Model: eCollection Cited Medium: Internet ISSN: 2633-0679 (Electronic) Linking ISSN: 26330679 NLM ISO Abbreviation: RSC Chem Biol Subsets: PubMed not MEDLINE

المؤلفون: Koehn OJ; Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA., Lorimer E; Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA., Unger B; Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA., Harris R; Department of Pediatrics and Human Development, College of Human Medicine, Michigan State University, Grand Rapids, Michigan, USA., Das AS; Department of Pediatrics and Human Development, College of Human Medicine, Michigan State University, Grand Rapids, Michigan, USA., Suazo KF; Department of Chemistry, University of Minnesota, Minneapolis, Minnesota, USA., Auger SA; Department of Chemistry, University of Minnesota, Minneapolis, Minnesota, USA., Distefano MD; Department of Chemistry, University of Minnesota, Minneapolis, Minnesota, USA., Prokop JW; Department of Pediatrics and Human Development, College of Human Medicine, Michigan State University, Grand Rapids, Michigan, USA; Department of Pharmacology and Toxicology, Michigan State University, East Lansing, Michigan, USA., Williams CL; Department of Pharmacology and Toxicology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA. Electronic address: williams@mcw.edu.

المصدر: The Journal of biological chemistry [J Biol Chem] 2023 Jun; Vol. 299 (6), pp. 104698. Date of Electronic Publication: 2023 Apr 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Monomeric GTP-Binding Proteins*/metabolism, Protein Isoforms/genetics ; Protein Isoforms/metabolism ; Prenylation ; rac1 GTP-Binding Protein/genetics ; rac1 GTP-Binding Protein/metabolism ; Protein Prenylation

المؤلفون: Petenkova A; Department of Medicine, Division of Infectious Diseases, Mass General Brigham, Harvard Medical School, Boston, MA, 02115, USA., Auger SA; Department of Chemistry, University of Minnesota, Minneapolis, MN, 55455, USA., Lamb J; Department of Medicine, Division of Infectious Diseases, Mass General Brigham, Harvard Medical School, Boston, MA, 02115, USA., Quellier D; Department of Medicine, Division of Infectious Diseases, Mass General Brigham, Harvard Medical School, Boston, MA, 02115, USA., Carter C; Department of Medicine, Division of Infectious Diseases, Mass General Brigham, Harvard Medical School, Boston, MA, 02115, USA., To OT; Department of Medicine, Division of Infectious Diseases, Mass General Brigham, Harvard Medical School, Boston, MA, 02115, USA., Milosevic J; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA., Barghout R; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA., Kugadas A; Department of Medicine, Division of Infectious Diseases, Mass General Brigham, Harvard Medical School, Boston, MA, 02115, USA., Lu X; Department of Medicine, Division of Infectious Diseases, Mass General Brigham, Harvard Medical School, Boston, MA, 02115, USA., Geddes-McAlister J; Molecular and Cellular Biology Department, University of Guelph, Guelph, ON, N1G 2W1, Canada., Fichorova R; Department of Obstetrics, Gynecology, and Reproductive Biology, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, 02115, USA., Sykes DB; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA, 02114, USA., Distefano MD; Department of Chemistry, University of Minnesota, Minneapolis, MN, 55455, USA., Gadjeva M; Department of Medicine, Division of Infectious Diseases, Mass General Brigham, Harvard Medical School, Boston, MA, 02115, USA. mgadjeva@fas.harvard.edu.; Harvard University, Faculty of Arts and Sciences, Cambridge, MA, 02138, USA. mgadjeva@fas.harvard.edu.

المصدر: Nature communications [Nat Commun] 2023 May 13; Vol. 14 (1), pp. 2761. Date of Electronic Publication: 2023 May 13.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Neutrophils* , Proteins*/metabolism, Animals ; Humans ; Mice ; Mice, Knockout ; Oxidoreductases/metabolism

المؤلفون: Jeong A; University of Minnesota, Minneapolis, Minnesota 55455, United States., Auger SA; University of Minnesota, Minneapolis, Minnesota 55455, United States., Maity S; University of Minnesota, Minneapolis, Minnesota 55455, United States., Fredriksen K; University of Minnesota, Minneapolis, Minnesota 55455, United States., Zhong R; University of Minnesota, Minneapolis, Minnesota 55455, United States., Li L; University of Minnesota, Minneapolis, Minnesota 55455, United States., Distefano MD; University of Minnesota, Minneapolis, Minnesota 55455, United States.

المصدر: ACS chemical biology [ACS Chem Biol] 2022 Oct 21; Vol. 17 (10), pp. 2863-2876. Date of Electronic Publication: 2022 Sep 15.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101282906 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1554-8937 (Electronic) Linking ISSN: 15548929 NLM ISO Abbreviation: ACS Chem Biol Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease*/drug therapy , Alzheimer Disease*/metabolism, Animals ; Mice ; Mice, Transgenic ; Proteomics/methods ; Protein Prenylation ; Proteins/metabolism ; Disease Models, Animal ; Brain/metabolism ; Terpenes/metabolism