المؤلفون: Chua KP; Genome Institute of Singapore, Singapore, Singapore., Teng YHF; Division of Medical Oncology, National Cancer Center Singapore, Singapore, Singapore.; Cancer Therapeutics Research Laboratory, National Cancer Center Singapore, Singapore, Singapore., Tan AC; Division of Medical Oncology, National Cancer Center Singapore, Singapore, Singapore.; Duke-NUS Medical School Singapore, Singapore., Takano A; Division of Pathology, Singapore General Hospital, Singapore, Singapore., Alvarez JJS; Genome Institute of Singapore, Singapore, Singapore., Nahar R; Genome Institute of Singapore, Singapore, Singapore., Rohatgi N; Genome Institute of Singapore, Singapore, Singapore., Lai GGY; Division of Medical Oncology, National Cancer Center Singapore, Singapore, Singapore., Aung ZW; Division of Medical Oncology, National Cancer Center Singapore, Singapore, Singapore., Yeong JPS; Division of Pathology, Singapore General Hospital, Singapore, Singapore., Lim KH; Division of Pathology, Singapore General Hospital, Singapore, Singapore., Naeini MM; Genome Institute of Singapore, Singapore, Singapore., Kassam I; Genome Institute of Singapore, Singapore, Singapore., Jain A; Division of Medical Oncology, National Cancer Center Singapore, Singapore, Singapore., Tan WL; Division of Medical Oncology, National Cancer Center Singapore, Singapore, Singapore., Gogna A; Department of Vascular and Interventional Radiology, Singapore General Hospital, Singapore, Singapore., Too CW; Department of Vascular and Interventional Radiology, Singapore General Hospital, Singapore, Singapore., Kanesvaran R; Division of Medical Oncology, National Cancer Center Singapore, Singapore, Singapore., Ng QS; Division of Medical Oncology, National Cancer Center Singapore, Singapore, Singapore., Ang MK; Division of Medical Oncology, National Cancer Center Singapore, Singapore, Singapore., Rajasekaran T; Division of Medical Oncology, National Cancer Center Singapore, Singapore, Singapore., Anantham D; Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore, Singapore., Phua GC; Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore, Singapore., Tan BS; Department of Vascular and Interventional Radiology, Singapore General Hospital, Singapore, Singapore., Lee YY; Genome Institute of Singapore, Singapore, Singapore., Wang L; Division of Medical Oncology, National Cancer Center Singapore, Singapore, Singapore., Teo ASM; Genome Institute of Singapore, Singapore, Singapore., Khng AJ; Genome Institute of Singapore, Singapore, Singapore., Lim MJ; Genome Institute of Singapore, Singapore, Singapore., Suteja L; Division of Medical Oncology, National Cancer Center Singapore, Singapore, Singapore., Toh CK; Division of Medical Oncology, National Cancer Center Singapore, Singapore, Singapore., Lim WT; Division of Medical Oncology, National Cancer Center Singapore, Singapore, Singapore.; Duke-NUS Medical School Singapore, Singapore.; IMCB NCC MPI Singapore Oncogenome Laboratory, Institute of Molecular and Cell Biology, Singapore, Singapore., Iyer NG; Cancer Therapeutics Research Laboratory, National Cancer Center Singapore, Singapore, Singapore.; Duke-NUS Medical School Singapore, Singapore.; Division of Surgical Oncology, National Cancer Center Singapore, Singapore, Singapore., Tam WL; Genome Institute of Singapore, Singapore, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore., Tan EH; Division of Medical Oncology, National Cancer Center Singapore, Singapore, Singapore., Zhai W; Genome Institute of Singapore, Singapore, Singapore.; Key Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, Beijing, China.; Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, Kunming, China., Hillmer AM; Genome Institute of Singapore, Singapore, Singapore.; Institute of Pathology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany., Skanderup AJ; Genome Institute of Singapore, Singapore, Singapore. daniel.tan.s.w@singhealth.com.sg skanderupamj@gis.a-star.edu.sg., Tan DSW; Genome Institute of Singapore, Singapore, Singapore. daniel.tan.s.w@singhealth.com.sg skanderupamj@gis.a-star.edu.sg.; Division of Medical Oncology, National Cancer Center Singapore, Singapore, Singapore.; Cancer Therapeutics Research Laboratory, National Cancer Center Singapore, Singapore, Singapore.; Duke-NUS Medical School Singapore, Singapore.

المصدر: Clinical cancer research : an official journal of the American Association for Cancer Research [Clin Cancer Res] 2021 Nov 01; Vol. 27 (21), pp. 5939-5950. Date of Electronic Publication: 2021 Jul 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 9502500 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3265 (Electronic) Linking ISSN: 10780432 NLM ISO Abbreviation: Clin Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Mutation*, Carcinoma, Non-Small-Cell Lung/*drug therapy , Carcinoma, Non-Small-Cell Lung/*genetics , Lung Neoplasms/*drug therapy , Lung Neoplasms/*genetics, ErbB Receptors/genetics ; Humans ; Protein-Tyrosine Kinases/genetics

المؤلفون: Ragasa C; Development Strategy and Governance Division (DSGD), International Food Policy Research Institute (IFPRI), Washington, District of Columbia, USA., Lambrecht I; Development Strategy and Governance Division (DSGD), International Food Policy Research Institute (IFPRI), Yangon, Myanmar., Mahrt K; Development Strategy and Governance Division (DSGD), International Food Policy Research Institute (IFPRI), Denver, Colorado, USA., Zhao H; Development Strategy and Governance Division (DSGD), International Food Policy Research Institute (IFPRI), Washington, District of Columbia, USA., Aung ZW; Development Strategy and Governance Division (DSGD), International Food Policy Research Institute (IFPRI), Nay Pyi Taw, Myanmar., Scott J; Gender and Nutrition, WorldFish, Yangon, Myanmar.

المصدر: Maternal & child nutrition [Matern Child Nutr] 2021 Oct; Vol. 17 (4), pp. e13259. Date of Electronic Publication: 2021 Aug 19.

نوع المنشور: Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101201025 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1740-8709 (Electronic) Linking ISSN: 17408695 NLM ISO Abbreviation: Matern Child Nutr Subsets: MEDLINE

مواضيع طبية MeSH: COVID-19*, Animals ; Diet ; Female ; Health Education ; Humans ; Myanmar ; SARS-CoV-2

المؤلفون: Ragasa C; International Food Policy Research Institute (IFPRI) Washington DC USA., Lambrecht I; International Food Policy Research Institute (IFPRI) Yangon Myanmar., Mahrt K; International Food Policy Research Institute (IFPRI) Colorado USA., Aung ZW; International Food Policy Research Institute (IFPRI) Yangon Myanmar., Wang M; International Food Policy Research Institute (IFPRI) Yangon Myanmar.

المصدر: Agricultural economics (Amsterdam, Netherlands) [Agric Econ] 2021 May; Vol. 52 (3), pp. 505-523. Date of Electronic Publication: 2021 May 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 101544386 Publication Model: Print-Electronic Cited Medium: Print ISSN: 0169-5150 (Print) Linking ISSN: 01695150 NLM ISO Abbreviation: Agric Econ Subsets: PubMed not MEDLINE

المؤلفون: Chen J; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Yang H; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; Key Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, Beijing, China., Teo ASM; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Amer LB; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Sherbaf FG; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Tan CQ; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Alvarez JJS; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Lu B; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Lim JQ; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Takano A; Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore., Nahar R; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Lee YY; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Phua CZJ; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Chua KP; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Suteja L; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore., Chen PJ; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Chang MM; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Koh TPT; Surgical Oncology, National Cancer Centre Singapore, Singapore, Singapore., Ong BH; Department of Cardiothoracic Surgery, National Heart Centre Singapore, Singapore, Singapore., Anantham D; Department of Respiratory & Critical Care Medicine, Singapore General Hospital, Singapore, Singapore., Hsu AAL; Department of Respiratory & Critical Care Medicine, Singapore General Hospital, Singapore, Singapore., Gogna A; Department of Vascular & Interventional Radiology, Singapore General Hospital, Singapore, Singapore., Too CW; Department of Vascular & Interventional Radiology, Singapore General Hospital, Singapore, Singapore., Aung ZW; Division of Clinical Trials and Epidemiological Sciences, National Cancer Centre Singapore, Singapore, Singapore., Lee YF; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore., Wang L; Division of Clinical Trials and Epidemiological Sciences, National Cancer Centre Singapore, Singapore, Singapore., Lim TKH; Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore., Wilm A; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Choi PS; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Ng PY; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Toh CK; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore., Lim WT; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore.; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Ma S; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Lim B; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Liu J; Centre for Quantitative Medicine, Program in Health Services and Systems Research, Duke-NUS Medical School, Singapore, Singapore., Tam WL; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore.; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore.; Cancer Science Institute of Singapore, National University of Singapore, Singapore, Singapore.; Department of Biochemistry, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Skanderup AJ; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Yeong JPS; Department of Anatomical Pathology, Singapore General Hospital, Singapore, Singapore.; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore., Tan EH; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore.; Division of Clinical Trials and Epidemiological Sciences, National Cancer Centre Singapore, Singapore, Singapore., Creasy CL; Oncology R&D, GlaxoSmithKline, Collegeville, PA, USA., Tan DSW; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore. daniel.tan.s.w@nccs.com.sg.; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore. daniel.tan.s.w@nccs.com.sg.; Cancer Therapeutics Research Laboratory, Division of Medical Sciences, National Cancer Centre Singapore, Singapore, Singapore. daniel.tan.s.w@nccs.com.sg., Hillmer AM; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore. ahillmer@uni-koeln.de.; Institute of Pathology, Faculty of Medicine and University Hospital Cologne, University of Cologne, Cologne, Germany. ahillmer@uni-koeln.de., Zhai W; Genome Institute of Singapore, Agency for Science, Technology and Research (A*STAR), Singapore, Singapore. weiweizhai@ioz.ac.cn.; Key Laboratory of Zoological Systematics and Evolution, Institute of Zoology, Chinese Academy of Sciences, Beijing, China. weiweizhai@ioz.ac.cn.; School of Biological Sciences, Nanyang Technological University, Singapore, Singapore. weiweizhai@ioz.ac.cn.; Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, Kunming, China. weiweizhai@ioz.ac.cn.

المصدر: Nature genetics [Nat Genet] 2020 Feb; Vol. 52 (2), pp. 177-186. Date of Electronic Publication: 2020 Feb 03.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE

مواضيع طبية MeSH: Mutation*, Adenocarcinoma of Lung/*genetics , Lung Neoplasms/*genetics, Adenocarcinoma of Lung/etiology ; Adenocarcinoma of Lung/mortality ; Adenocarcinoma of Lung/therapy ; Aged ; Asian People/genetics ; Cohort Studies ; DNA Copy Number Variations ; ErbB Receptors/genetics ; Exome ; Female ; Gene Expression Profiling ; Humans ; Lung Neoplasms/etiology ; Lung Neoplasms/mortality ; Lung Neoplasms/therapy ; Male ; Middle Aged ; Proto-Oncogene Proteins p21(ras)/genetics ; Singapore ; Tumor Suppressor Protein p53/genetics

المؤلفون: Tan AC; Division of Medical Oncology, National Cancer Centre Singapore, Singapore., Lai GGY; Division of Medical Oncology, National Cancer Centre Singapore, Singapore., Tan GS; Division of Pathology, Singapore General Hospital, Singapore., Poon SY; Division of Medical Oncology, National Cancer Centre Singapore, Singapore., Doble B; Duke-NUS Medical School, National University of Singapore, Singapore., Lim TH; Division of Pathology, Singapore General Hospital, Singapore., Aung ZW; Division of Medical Oncology, National Cancer Centre Singapore, Singapore., Takano A; Division of Pathology, Singapore General Hospital, Singapore; Duke-NUS Medical School, National University of Singapore, Singapore., Tan WL; Division of Medical Oncology, National Cancer Centre Singapore, Singapore., Ang MK; Division of Medical Oncology, National Cancer Centre Singapore, Singapore; Duke-NUS Medical School, National University of Singapore, Singapore., Tan BS; Duke-NUS Medical School, National University of Singapore, Singapore; Department of Vascular and Interventional Radiology, Singapore General Hospital, Singapore., Devanand A; Duke-NUS Medical School, National University of Singapore, Singapore; Department of Respiratory and Critical Care Medicine, Singapore General Hospital, Singapore., Too CW; Duke-NUS Medical School, National University of Singapore, Singapore; Department of Vascular and Interventional Radiology, Singapore General Hospital, Singapore., Gogna A; Duke-NUS Medical School, National University of Singapore, Singapore; Department of Vascular and Interventional Radiology, Singapore General Hospital, Singapore., Ong BH; Duke-NUS Medical School, National University of Singapore, Singapore; Department of Cardiothoracic Surgery, National Heart Centre Singapore, Singapore., Koh TPT; Division of Medical Oncology, National Cancer Centre Singapore, Singapore., Kanesvaran R; Division of Medical Oncology, National Cancer Centre Singapore, Singapore; Duke-NUS Medical School, National University of Singapore, Singapore., Ng QS; Division of Medical Oncology, National Cancer Centre Singapore, Singapore., Jain A; Division of Medical Oncology, National Cancer Centre Singapore, Singapore; Duke-NUS Medical School, National University of Singapore, Singapore., Rajasekaran T; Division of Medical Oncology, National Cancer Centre Singapore, Singapore; Duke-NUS Medical School, National University of Singapore, Singapore., Lim AST; Division of Pathology, Singapore General Hospital, Singapore; Duke-NUS Medical School, National University of Singapore, Singapore., Lim WT; Division of Medical Oncology, National Cancer Centre Singapore, Singapore; Duke-NUS Medical School, National University of Singapore, Singapore., Toh CK; Division of Medical Oncology, National Cancer Centre Singapore, Singapore; Duke-NUS Medical School, National University of Singapore, Singapore., Tan EH; Division of Medical Oncology, National Cancer Centre Singapore, Singapore; Duke-NUS Medical School, National University of Singapore, Singapore., Lim TKH; Division of Pathology, Singapore General Hospital, Singapore; Duke-NUS Medical School, National University of Singapore, Singapore., Tan DSW; Division of Medical Oncology, National Cancer Centre Singapore, Singapore; Duke-NUS Medical School, National University of Singapore, Singapore. Electronic address: daniel.tan.s.w@singhealth.com.sg.

المصدر: Lung cancer (Amsterdam, Netherlands) [Lung Cancer] 2020 Jan; Vol. 139, pp. 207-215. Date of Electronic Publication: 2019 Nov 26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Scientific Publishers Country of Publication: Ireland NLM ID: 8800805 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8332 (Electronic) Linking ISSN: 01695002 NLM ISO Abbreviation: Lung Cancer Subsets: MEDLINE

مواضيع طبية MeSH: Cost-Benefit Analysis* , Molecular Targeted Therapy*, Adenocarcinoma of Lung/*pathology , Antineoplastic Combined Chemotherapy Protocols/*therapeutic use , Carcinoma, Non-Small-Cell Lung/*pathology , High-Throughput Nucleotide Sequencing/*methods , Lung Neoplasms/*pathology, Adenocarcinoma of Lung/drug therapy ; Adenocarcinoma of Lung/economics ; Adenocarcinoma of Lung/genetics ; Adult ; Aged ; Aged, 80 and over ; Asia ; Biomarkers, Tumor/genetics ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Carcinoma, Non-Small-Cell Lung/economics ; Carcinoma, Non-Small-Cell Lung/genetics ; ErbB Receptors/genetics ; Female ; Follow-Up Studies ; Humans ; Lung Neoplasms/drug therapy ; Lung Neoplasms/economics ; Lung Neoplasms/genetics ; Male ; Middle Aged ; Mutation ; Prognosis ; Retrospective Studies

المؤلفون: Lai GGY; 1 National Cancer Centre Singapore, Singapore., Lim TH; 2 Singapore General Hospital, Singapore., Lim J; 1 National Cancer Centre Singapore, Singapore., Liew PJR; 2 Singapore General Hospital, Singapore., Kwang XL; 1 National Cancer Centre Singapore, Singapore., Nahar R; 3 Genome Institute of Singapore, Singapore., Aung ZW; 1 National Cancer Centre Singapore, Singapore., Takano A; 2 Singapore General Hospital, Singapore., Lee YY; 3 Genome Institute of Singapore, Singapore., Lau DPX; 1 National Cancer Centre Singapore, Singapore., Tan GS; 2 Singapore General Hospital, Singapore., Tan SH; 1 National Cancer Centre Singapore, Singapore., Tan WL; 1 National Cancer Centre Singapore, Singapore., Ang MK; 1 National Cancer Centre Singapore, Singapore., Toh CK; 1 National Cancer Centre Singapore, Singapore., Tan BS; 2 Singapore General Hospital, Singapore., Devanand A; 2 Singapore General Hospital, Singapore., Too CW; 2 Singapore General Hospital, Singapore., Gogna A; 2 Singapore General Hospital, Singapore., Ong BH; 4 National Heart Centre Singapore, Singapore., Koh TPT; 1 National Cancer Centre Singapore, Singapore., Kanesvaran R; 1 National Cancer Centre Singapore, Singapore., Ng QS; 1 National Cancer Centre Singapore, Singapore., Jain A; 1 National Cancer Centre Singapore, Singapore., Rajasekaran T; 1 National Cancer Centre Singapore, Singapore., Yuan J; 3 Genome Institute of Singapore, Singapore., Lim TKH; 2 Singapore General Hospital, Singapore., Lim AST; 2 Singapore General Hospital, Singapore., Hillmer AM; 3 Genome Institute of Singapore, Singapore., Lim WT; 1 National Cancer Centre Singapore, Singapore., Iyer NG; 1 National Cancer Centre Singapore, Singapore., Tam WL; 3 Genome Institute of Singapore, Singapore., Zhai W; 3 Genome Institute of Singapore, Singapore., Tan EH; 1 National Cancer Centre Singapore, Singapore., Tan DSW; 1 National Cancer Centre Singapore, Singapore.; 3 Genome Institute of Singapore, Singapore.

المصدر: Journal of clinical oncology : official journal of the American Society of Clinical Oncology [J Clin Oncol] 2019 Apr 10; Vol. 37 (11), pp. 876-884. Date of Electronic Publication: 2019 Jan 24.

نوع المنشور: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society of Clinical Oncology Country of Publication: United States NLM ID: 8309333 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-7755 (Electronic) Linking ISSN: 0732183X NLM ISO Abbreviation: J Clin Oncol Subsets: MEDLINE

مواضيع طبية MeSH: Gene Amplification* , Gene Dosage* , Mutation*, Biomarkers, Tumor/*genetics , Carcinoma, Non-Small-Cell Lung/*genetics , Drug Resistance, Neoplasm/*genetics , Lung Neoplasms/*genetics , Proto-Oncogene Proteins c-met/*genetics, Antineoplastic Agents/therapeutic use ; Carcinoma, Non-Small-Cell Lung/drug therapy ; Carcinoma, Non-Small-Cell Lung/enzymology ; Carcinoma, Non-Small-Cell Lung/secondary ; Cell Line, Tumor ; Databases, Factual ; ErbB Receptors/antagonists & inhibitors ; ErbB Receptors/genetics ; ErbB Receptors/metabolism ; Genetic Heterogeneity ; Humans ; In Situ Hybridization, Fluorescence ; Lung Neoplasms/drug therapy ; Lung Neoplasms/enzymology ; Lung Neoplasms/pathology ; Predictive Value of Tests ; Protein Kinase Inhibitors/therapeutic use ; Reproducibility of Results ; Retrospective Studies

المؤلفون: Nahar R; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore, 138672, Singapore., Zhai W; Human Genetics, Genome Institute of Singapore, Singapore, 138672, Singapore.; School of Biological Sciences, Nanyang Technological University, Singapore, 637551, Singapore., Zhang T; Human Genetics, Genome Institute of Singapore, Singapore, 138672, Singapore., Takano A; Department of Pathology, Singapore General Hospital, Singapore, 169608, Singapore., Khng AJ; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore, 138672, Singapore., Lee YY; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore, 138672, Singapore., Liu X; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore, 138672, Singapore., Lim CH; Department of Cardiothoracic Surgery, National Heart Centre Singapore, Singapore, 169609, Singapore., Koh TPT; Department of Cardiothoracic Surgery, National Heart Centre Singapore, Singapore, 169609, Singapore., Aung ZW; Division of Clinical Trials and Epidemiological Sciences, National Cancer Centre Singapore, Singapore, 169610, Singapore., Lim TKH; Department of Pathology, Singapore General Hospital, Singapore, 169608, Singapore., Veeravalli L; Research Pipeline Development, Genome Institute of Singapore, Singapore, 138672, Singapore., Yuan J; Cancer Stem Cell Biology, Genome Institute of Singapore, Singapore, 138672, Singapore., Teo ASM; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore, 138672, Singapore., Chan CX; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore, 138672, Singapore., Poh HM; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore, 138672, Singapore., Chua IML; Next Generation Sequencing Platform, Genome Institute of Singapore, Singapore, 138672, Singapore., Liew AA; Cancer Stem Cell Biology, Genome Institute of Singapore, Singapore, 138672, Singapore.; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, 169610, Singapore.; Cancer Therapeutics Research Laboratory, Division of Medical Sciences, National Cancer Centre Singapore, Singapore, 169610, Singapore., Lau DPX; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, 169610, Singapore.; Cancer Therapeutics Research Laboratory, Division of Medical Sciences, National Cancer Centre Singapore, Singapore, 169610, Singapore., Kwang XL; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, 169610, Singapore.; Cancer Therapeutics Research Laboratory, Division of Medical Sciences, National Cancer Centre Singapore, Singapore, 169610, Singapore., Toh CK; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, 169610, Singapore., Lim WT; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, 169610, Singapore., Lim B; Cancer Stem Cell Biology, Genome Institute of Singapore, Singapore, 138672, Singapore., Tam WL; Cancer Stem Cell Biology, Genome Institute of Singapore, Singapore, 138672, Singapore., Tan EH; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, 169610, Singapore., Hillmer AM; Cancer Therapeutics and Stratified Oncology, Genome Institute of Singapore, Singapore, 138672, Singapore. axel.hillmer@uk-koeln.de.; Institute of Pathology, University Hospital Cologne, 50937, Cologne, Germany. axel.hillmer@uk-koeln.de., Tan DSW; Cancer Stem Cell Biology, Genome Institute of Singapore, Singapore, 138672, Singapore. daniel.tan.s.w@nccs.com.sg.; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, 169610, Singapore. daniel.tan.s.w@nccs.com.sg.; Cancer Therapeutics Research Laboratory, Division of Medical Sciences, National Cancer Centre Singapore, Singapore, 169610, Singapore. daniel.tan.s.w@nccs.com.sg.

المصدر: Nature communications [Nat Commun] 2018 Jan 15; Vol. 9 (1), pp. 216. Date of Electronic Publication: 2018 Jan 15.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Mutation*, Adenocarcinoma/*genetics , ErbB Receptors/*genetics , Genomics/*methods , Lung Neoplasms/*genetics , Exome Sequencing/*methods, Adenocarcinoma/ethnology ; Adenocarcinoma/pathology ; Asian People/genetics ; Cell Line, Tumor ; Drug Resistance, Neoplasm/drug effects ; Drug Resistance, Neoplasm/genetics ; Genetic Predisposition to Disease/ethnology ; Genetic Predisposition to Disease/genetics ; Humans ; Lung Neoplasms/ethnology ; Lung Neoplasms/pathology ; Protein Kinase Inhibitors/pharmacology