المؤلفون: Hua V Lin, Dunlu Chen, Zhu Shen, Lei Zhu, Xuesong Ouyang, Aurawan Vongs, Yanqing Kan, John M Levorse, Edward J Kowalik, Daphne M Szeto, Xiaorui Yao, Jianying Xiao, Shirley Chen, Jinqi Liu, Marga Garcia-Calvo, Myung K Shin, Shirly Pinto

المصدر: PLoS ONE, Vol 8, Iss 1, p e54480 (2013)

مصطلحات موضوعية: Medicine, Science

وصف الملف: electronic resource

Relation: http://europepmc.org/articles/PMC3545956?pdf=render; https://doaj.org/toc/1932-6203

URL الوصول: https://doaj.org/article/04d6fea951f2478297b3dfeed85ea767

المؤلفون: Doreen E. Cashen, Constantin Tamvakopoulos, Qianping Peng, William J. Martin, David H. Weinberg, Charles Rosenblum, Arthur A. Patchett, Tanya MacNeil, Patrick G. Pollard, Zhixiong Ye, Raman K. Bakshi, Ralph A. Stearns, Rubana N. Kalyani, Palucki Brenda, Joseph M. Metzger, Alison M. Strack, Lex H.T. Van der Ploeg, D. Euan MacIntyre, Iyassu K. Sebhat, Aurawan Vongs, Airu S. Chen, Ravi P. Nargund, Liangqin Guo, Matthew J. Wyvratt, Randy R. Miller, Rui Tang, Howard Y. Chen, Khaled J. Barakat

المصدر: Bioorganic & Medicinal Chemistry Letters. 15:3501-3505

مصطلحات موضوعية: Male, Agonist, Quinuclidines, Time Factors, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Rodentia, Carboxamide, Biochemistry, Chemical synthesis, Piperazines, Rats, Sprague-Dawley, Eating, Structure-Activity Relationship, Piperidines, In vivo, Drug Discovery, medicine, Animals, Humans, Receptor, Molecular Biology, Aza Compounds, Bicyclic molecule, Chemistry, Penile Erection, digestive, oral, and skin physiology, Organic Chemistry, Small molecule, Rats, Microsomes, Liver, Receptor, Melanocortin, Type 4, Molecular Medicine, Melanocortin, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::eec96b03aa1e5f2ba3d3c429b0a51544
https://doi.org/10.1016/j.bmcl.2005.05.109

المؤلفون: George A. Doss, Lex H.T. Van der Ploeg, Qianping Peng, Ravi P. Nargund, Charles Rosenblum, Randall R. Miller, Aurawan Vongs, Palucki Brenda, Tanya MacNeil, Ralph A. Stearns, Min K. Park, David H. Weinberg, Rui Tang, Arthur A. Patchett, Constantin Tamvakopoulos

المصدر: Bioorganic & Medicinal Chemistry Letters. 15:1993-1996

مصطلحات موضوعية: Agonist, Stereochemistry, medicine.drug_class, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, Biochemistry, Piperazines, Structure-Activity Relationship, chemistry.chemical_compound, Drug Discovery, medicine, Humans, Receptor, Molecular Biology, biology, Chemistry, Organic Chemistry, biology.organism_classification, In vitro, Piperazine, Microsoma, Microsome, Receptor, Melanocortin, Type 4, Molecular Medicine, Melanocortin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::44e32b60eac4ad2438147bfe723f3834
https://doi.org/10.1016/j.bmcl.2005.02.068

المؤلفون: William J. Martin, D. Euan MacIntyre, Ravi P. Nargund, Rubana N. Kalyani, Rui Tang, George A. Doss, Min K. Park, Alison M. Strack, Erin McGowan, Joseph M. Metzger, Charles Rosenblum, Randall R. Miller, Palucki Brenda, Qianping Peng, Arthur A. Patchett, Ralph A. Stearns, Patrick G. Pollard, Lex H.T. Van der Ploeg, Iyassu K. Sebhat, Constantin Tamvakopoulos, Cherrie Shepherd, Aurawan Vongs, Tanya MacNeil, David H. Weinberg, Zhixiong Ye

المصدر: Bioorganic & Medicinal Chemistry Letters. 15:171-175

مصطلحات موضوعية: Male, Agonist, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, Biochemistry, Chemical synthesis, Piperazines, Mice, Dogs, Erectile Dysfunction, Piperidines, In vivo, Drug Discovery, medicine, Animals, Obesity, Receptor, Molecular Biology, Chemistry, Organic Chemistry, Haplorhini, In vitro, Rats, Receptor, Melanocortin, Type 4, Molecular Medicine, Melanocortin

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::38e9173e9b0b0823886380b760b7694a
https://doi.org/10.1016/j.bmcl.2004.10.020

المؤلفون: Charles Rosenblum, Nicole M Lynn, Aurawan Vongs

المصدر: Regulatory Peptides. 120:113-118

مصطلحات موضوعية: endocrine system, Physiology, Morpholines, Clinical Biochemistry, CHO Cells, Mitogen-activated protein kinase kinase, environment and public health, Biochemistry, MAP2K7, Wortmannin, Phosphatidylinositol 3-Kinases, Cellular and Molecular Neuroscience, chemistry.chemical_compound, Endocrinology, Cricetinae, Cyclic AMP, Animals, ASK1, Melanocyte-Stimulating Hormones, c-Raf, Enzyme Inhibitors, Protein kinase A, Protein Kinase Inhibitors, Cells, Cultured, Mitogen-Activated Protein Kinase 3, MAP kinase kinase kinase, Chemistry, Akt/PKB signaling pathway, Cyclic AMP-Dependent Protein Kinases, Cell biology, Androstadienes, Enzyme Activation, enzymes and coenzymes (carbohydrates), Chromones, Receptor, Melanocortin, Type 4, biological phenomena, cell phenomena, and immunity, hormones, hormone substitutes, and hormone antagonists, Signal Transduction

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::88b965d0e7dc7592dc97e6e1dca75bf8
https://doi.org/10.1016/j.regpep.2004.02.018

المؤلفون: Mark T. Goulet, Lihu Yang, Aurawan Vongs, David H. Weinberg, Charles Rosenblum, Changyou Zhou, Feroze Ujjainwalla, Thomas F. Walsh, Matthew J. Wyvratt, Tanya MacNeil, Rubana N. Kalyani, Rui Tang, Lex H.T. Van der Ploeg, Warner Daniel

المصدر: Bioorganic & Medicinal Chemistry Letters. 13:4431-4435

مصطلحات موضوعية: Agonist, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Molecular Conformation, Pharmaceutical Science, Biochemistry, Chemical synthesis, Mice, Structure-Activity Relationship, Drug Discovery, medicine, Animals, Humans, Receptor, Molecular Biology, Archetype, Binding Sites, integumentary system, Chemistry, digestive, oral, and skin physiology, Organic Chemistry, Stereoisomerism, Pyridazines, Kinetics, Receptor, Melanocortin, Type 4, Molecular Medicine, Indicators and Reagents, Melanocortin, hormones, hormone substitutes, and hormone antagonists

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a9d2c34bd9e7e724008bb422d642c2fd
https://doi.org/10.1016/j.bmcl.2003.09.026

المؤلفون: Christopher P. Austin, Doreen E. Cashen, Sheng-Shung Pong, Brian D. Spar, Brett Connolly, Tung Ming Fong, D. Euan MacIntyre, Carina P. Tan, Michael R. Tota, Ravi P. Nargund, R. S. L. Chang, Oksana C. Palyha, Constantin Tamvakopoulos, Deborah L. Drazen, Anthony G. DiLella, Jennifer E. Drisko, David J. Figueroa, Tanya MacNeil, Andreas W. Sailer, David H. Weinberg, Randy J. Nelson, Charles Rosenblum, Cathy R.-R.C. Huang, Rui Tang, Arthur A. Patchett, Xiao-Ming Guan, Hong Yu, George J. Christ, Andrew D. Howard, Lex H.T. Van der Ploeg, William J. Martin, Aurawan Vongs, Iyassu K. Sebhat, Ralph A. Stearns

المصدر: Proceedings of the National Academy of Sciences. 99:11381-11386

مصطلحات موضوعية: Male, Agonist, medicine.medical_specialty, DNA, Complementary, Intracranial Pressure, medicine.drug_class, Blood Pressure, In Vitro Techniques, Biology, Somatosensory system, Mice, Sexual Behavior, Animal, Nerve Fibers, Internal medicine, Copulation, medicine, Animals, Glans, In Situ Hybridization, DNA Primers, Multidisciplinary, Reverse Transcriptase Polymerase Chain Reaction, Human penis, Feeding Behavior, Ribonuclease, Pancreatic, Biological Sciences, Spinal cord, Electric Stimulation, Mice, Inbred C57BL, Melanocortin 4 receptor, medicine.anatomical_structure, Endocrinology, Receptors, Corticotropin, Models, Animal, Receptor, Melanocortin, Type 4, Brainstem, Energy Metabolism, Penis

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::341db11f0e12a0307d07e04176cd4aad
https://doi.org/10.1073/pnas.172378699

المؤلفون: Xiao-Ming Guan, Charles Rosenblum, Hong Yu, Yue Feng, D. Euan MacIntyre, Alison M. Strack, Lex H.T. Van der Ploeg, Christian N. Nunes, Airu S. Chen, Joseph M. Metzger, Linhai Cao, Easter G. Frazier, Jill K. Fisher, Ramon E. Camacho, William Min, Shobhna Gopal-Truter, Aurawan Vongs, Howard Y. Chen, Theodore N. Mellin, Donald J. Marsh, Myrna E. Trumbauer

المصدر: Nature Genetics. 26:97-102

مصطلحات موضوعية: Leptin, Male, Time Factors, Energy homeostasis, Body Temperature, Mice, Insulin, Protein Isoforms, Tissue Distribution, In Situ Hybridization, Mice, Knockout, Recombination, Genetic, Age Factors, Melanocortin 3 receptor, Blotting, Southern, Phenotype, medicine.anatomical_structure, Adipose Tissue, Receptor, Melanocortin, Type 4, Female, medicine.symptom, Melanocortin, Oligopeptides, Receptor, Melanocortin, Type 3, medicine.medical_specialty, Genotype, Receptors, Peptide, Calorimetry, Motor Activity, Biology, Feed conversion ratio, Melanocortin receptor, Central melanocortin system, Hyperinsulinism, Internal medicine, Genetics, medicine, Animals, Humans, Obesity, Models, Genetic, Body Weight, Feeding Behavior, Thyroxine, Glucose, Endocrinology, Receptors, Corticotropin, alpha-MSH, Lean body mass, Corticosterone, Weight gain

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0d4ce2d771382f4fed6e69e47dad7818
https://doi.org/10.1038/79254

المؤلفون: Jeffrey P Varnerin, T. Smith, Aurawan Vongs, Patricia J. Hey, M. Chou, Joseph J. King, Theodore N. Mellin, Easter G. Frazier, Michael R. Tota, D. E. Macintyre, Beth Junker, Beth Ann Murphy, Charles Rosenblum, Christian N. Nunes, B. W. Burgess, L. H. T. Van Der Ploeg

المصدر: Protein Expression and Purification. 14:335-342

مصطلحات موضوعية: Leptin, Protein Folding, medicine.medical_specialty, Recombinant Fusion Proteins, medicine.medical_treatment, Genetic Vectors, Radioimmunoassay, Mice, Obese, Inclusion bodies, Cell Line, Mice, In vivo, Internal medicine, Weight Loss, Escherichia coli, medicine, Animals, Humans, Histidine, Inclusion Bodies, Leptin receptor, Chemistry, Insulin, digestive, oral, and skin physiology, Proteins, Mice, Mutant Strains, Endotoxins, Diafiltration, Endocrinology, Biochemistry, Protein Biosynthesis, Biological Assay, Peptides, Filtration, hormones, hormone substitutes, and hormone antagonists, Ex vivo, Biotechnology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::705b75a96fc42e5528be2f6399035bb7
https://doi.org/10.1006/prep.1998.0978

المؤلفون: Myung K. Shin, Shirley Chen, Lei Zhu, Xuesong Ouyang, Zhu Shen, Marga Garcia-Calvo, Yanqing Kan, Daphne Szeto, Xiaorui Yao, John Levorse, Dunlu Chen, Jianying Xiao, Jinqi Liu, Aurawan Vongs, Shirly Pinto, Hua V. Lin, Edward J. Kowalik

المصدر: PLoS ONE, Vol 8, Iss 1, p e54480 (2013)
PLoS ONE

مصطلحات موضوعية: Male, Mouse, Gene Dosage, lcsh:Medicine, Biochemistry, Mice, Glucagon-Like Peptide 1, Gene Order, lcsh:Science, Mice, Knockout, Multidisciplinary, digestive, oral, and skin physiology, Animal Models, Postprandial Period, Glucagon-like peptide-1, Lipids, Postprandial, Medicine, Female, Research Article, medicine.medical_specialty, Genotype, Dipeptidyl Peptidase 4, Molecular Sequence Data, Biology, Gastrointestinal Hormones, Model Organisms, Dogs, Internal medicine, medicine, Animals, Secretion, Obesity, Diacylglycerol O-Acyltransferase, Triglycerides, Diacylglycerol kinase, Nutrition, Gastric emptying, Base Sequence, lcsh:R, Lipid metabolism, Lipid Metabolism, Diet, Enzyme Activation, Gastrointestinal Tract, Endocrinology, Metabolism, Gastric Emptying, Gene Expression Regulation, Peptide YY, Metabolic Disorders, lcsh:Q, Hormone

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc0627cc7b3bf91efdbc080a9e167631
http://europepmc.org/articles/PMC3545956?pdf=render