المؤلفون: Xia, XF, Jung, DJ, Webb, P, Zhang, AJ, Zhang, B, Li, LF, Ayers, SD, Gabbi, C, Ueno, Y, Gustafsson, JA, Alpini, G, Moore, DD, LeSage, GD

المصدر: Hepatology (Baltimore, Md.). 56(6):2288-2296

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:126070329

المؤلفون: Zhang A; Houston Methodist Research InstituteGenomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USACollege of Arts and SciencesChemistry Department, Indiana University Bloomington, Bloomington, Indiana, USADepartments of PaediatricsOncology, and Physiology and Pharmacology, University of Western Ontario, London, Ontario, CanadaChildren's Health Research InstituteLondon, Ontario, CanadaDepartment of Molecular Physiology and BiophysicsBaylor College of Medicine, Houston, Texas, USAThe Third Affiliated Hospital of Guangzhou Medical UniversityGuangzhou, China., Sieglaff DH; Houston Methodist Research InstituteGenomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USACollege of Arts and SciencesChemistry Department, Indiana University Bloomington, Bloomington, Indiana, USADepartments of PaediatricsOncology, and Physiology and Pharmacology, University of Western Ontario, London, Ontario, CanadaChildren's Health Research InstituteLondon, Ontario, CanadaDepartment of Molecular Physiology and BiophysicsBaylor College of Medicine, Houston, Texas, USAThe Third Affiliated Hospital of Guangzhou Medical UniversityGuangzhou, China., York JP; Houston Methodist Research InstituteGenomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USACollege of Arts and SciencesChemistry Department, Indiana University Bloomington, Bloomington, Indiana, USADepartments of PaediatricsOncology, and Physiology and Pharmacology, University of Western Ontario, London, Ontario, CanadaChildren's Health Research InstituteLondon, Ontario, CanadaDepartment of Molecular Physiology and BiophysicsBaylor College of Medicine, Houston, Texas, USAThe Third Affiliated Hospital of Guangzhou Medical UniversityGuangzhou, China., Suh JH; Houston Methodist Research InstituteGenomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USACollege of Arts and SciencesChemistry Department, Indiana University Bloomington, Bloomington, Indiana, USADepartments of PaediatricsOncology, and Physiology and Pharmacology, University of Western Ontario, London, Ontario, CanadaChildren's Health Research InstituteLondon, Ontario, CanadaDepartment of Molecular Physiology and BiophysicsBaylor College of Medicine, Houston, Texas, USAThe Third Affiliated Hospital of Guangzhou Medical UniversityGuangzhou, China., Ayers SD; Houston Methodist Research InstituteGenomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USACollege of Arts and SciencesChemistry Department, Indiana University Bloomington, Bloomington, Indiana, USADepartments of PaediatricsOncology, and Physiology and Pharmacology, University of Western Ontario, London, Ontario, CanadaChildren's Health Research InstituteLondon, Ontario, CanadaDepartment of Molecular Physiology and BiophysicsBaylor College of Medicine, Houston, Texas, USAThe Third Affiliated Hospital of Guangzhou Medical UniversityGuangzhou, China., Winnier GE; Houston Methodist Research InstituteGenomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USACollege of Arts and SciencesChemistry Department, Indiana University Bloomington, Bloomington, Indiana, USADepartments of PaediatricsOncology, and Physiology and Pharmacology, University of Western Ontario, London, Ontario, CanadaChildren's Health Research InstituteLondon, Ontario, CanadaDepartment of Molecular Physiology and BiophysicsBaylor College of Medicine, Houston, Texas, USAThe Third Affiliated Hospital of Guangzhou Medical UniversityGuangzhou, China., Kharitonenkov A; Houston Methodist Research InstituteGenomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USACollege of Arts and SciencesChemistry Department, Indiana University Bloomington, Bloomington, Indiana, USADepartments of PaediatricsOncology, and Physiology and Pharmacology, University of Western Ontario, London, Ontario, CanadaChildren's Health Research InstituteLondon, Ontario, CanadaDepartment of Molecular Physiology and BiophysicsBaylor College of Medicine, Houston, Texas, USAThe Third Affiliated Hospital of Guangzhou Medical UniversityGuangzhou, China., Pin C; Houston Methodist Research InstituteGenomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USACollege of Arts and SciencesChemistry Department, Indiana University Bloomington, Bloomington, Indiana, USADepartments of PaediatricsOncology, and Physiology and Pharmacology, University of Western Ontario, London, Ontario, CanadaChildren's Health Research InstituteLondon, Ontario, CanadaDepartment of Molecular Physiology and BiophysicsBaylor College of Medicine, Houston, Texas, USAThe Third Affiliated Hospital of Guangzhou Medical UniversityGuangzhou, China Houston Methodist Research InstituteGenomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USACollege of Arts and SciencesChemistry Department, Indiana University Bloomington, Bloomington, Indiana, USADepartments of PaediatricsOncology, and Physiology and Pharmacology, University of Western Ontario, London, Ontario, CanadaChildren's Health Research InstituteLondon, Ontario, CanadaDepartment of Molecular Physiology and BiophysicsBaylor College of Medicine, Houston, Texas, USAThe Third Affiliated Hospital of Guangzhou Medical UniversityGuangzhou, China., Zhang P; Houston Methodist Research InstituteGenomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USACollege of Arts and SciencesChemistry Department, Indiana University Bloomington, Bloomington, Indiana, USADepartments of PaediatricsOncology, and Physiology and Pharmacology, University of Western Ontario, London, Ontario, CanadaChildren's Health Research InstituteLondon, Ontario, CanadaDepartment of Molecular Physiology and BiophysicsBaylor College of Medicine, Houston, Texas, USAThe Third Affiliated Hospital of Guangzhou Medical UniversityGuangzhou, China., Webb P; Houston Methodist Research InstituteGenomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USACollege of Arts and SciencesChemistry Department, Indiana University Bloomington, Bloomington, Indiana, USADepartments of PaediatricsOncology, and Physiology and Pharmacology, University of Western Ontario, London, Ontario, CanadaChildren's Health Research InstituteLondon, Ontario, CanadaDepartment of Molecular Physiology and BiophysicsBaylor College of Medicine, Houston, Texas, USAThe Third Affiliated Hospital of Guangzhou Medical UniversityGuangzhou, China xxia2@tmhs.org pwebb@tmhs.org., Xia X; Houston Methodist Research InstituteGenomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USACollege of Arts and SciencesChemistry Department, Indiana University Bloomington, Bloomington, Indiana, USADepartments of PaediatricsOncology, and Physiology and Pharmacology, University of Western Ontario, London, Ontario, CanadaChildren's Health Research InstituteLondon, Ontario, CanadaDepartment of Molecular Physiology and BiophysicsBaylor College of Medicine, Houston, Texas, USAThe Third Affiliated Hospital of Guangzhou Medical UniversityGuangzhou, China Houston Methodist Research InstituteGenomic Medicine Program, 6670 Bertner Ave, Houston, Texas 77030, USACollege of Arts and SciencesChemistry Department, Indiana University Bloomington, Bloomington, Indiana, USADepartments of PaediatricsOncology, and Physiology and Pharmacology, University of Western Ontario, London, Ontario, CanadaChildren's Health Research InstituteLondon, Ontario, CanadaDepartment of Molecular Physiology and BiophysicsBaylor College of Medicine, Houston, Texas, USAThe Third Affiliated Hospital of Guangzhou Medical UniversityGuangzhou, China xxia2@tmhs.org pwebb@tmhs.org.

المصدر: The Journal of endocrinology [J Endocrinol] 2015 Mar; Vol. 224 (3), pp. 289-301. Date of Electronic Publication: 2014 Dec 11.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BioScientifica Country of Publication: England NLM ID: 0375363 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1479-6805 (Electronic) Linking ISSN: 00220795 NLM ISO Abbreviation: J Endocrinol Subsets: MEDLINE

مواضيع طبية MeSH: Fibroblast Growth Factors/*physiology , Liver/*metabolism , Thyroid Hormone Receptors beta/*physiology, Animals ; Fibroblast Growth Factors/genetics ; Gene Expression Profiling ; Gene Expression Regulation/drug effects ; Hep G2 Cells ; Hepatocytes/metabolism ; Humans ; Liver/drug effects ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Microarray Analysis ; Response Elements ; Triiodothyronine/pharmacology

المؤلفون: Lammel Lindemann JA; Houston Methodist Research Institute, Houston, Texas, United States; Escuela de Biotecnología y Alimentos, Instituto Tecnológico y de Estudios Superiores de Monterrey, Mexico., Angajala A; Houston Methodist Research Institute, Houston, Texas, United States., Engler DA; Houston Methodist Research Institute, Houston, Texas, United States., Webb P; Houston Methodist Research Institute, Houston, Texas, United States; Escuela de Biotecnología y Alimentos, Instituto Tecnológico y de Estudios Superiores de Monterrey, Mexico. Electronic address: PWebb@tmhs.org., Ayers SD; Houston Methodist Research Institute, Houston, Texas, United States. Electronic address: SDAyers@tmhs.org.

المصدر: Molecular and cellular endocrinology [Mol Cell Endocrinol] 2014 May 05; Vol. 388 (1-2), pp. 32-40. Date of Electronic Publication: 2014 Feb 25.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: North Holland Publishing Country of Publication: Ireland NLM ID: 7500844 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1872-8057 (Electronic) Linking ISSN: 03037207 NLM ISO Abbreviation: Mol Cell Endocrinol Subsets: MEDLINE

مواضيع طبية MeSH: Cholesterol 7-alpha-Hydroxylase/*genetics , Thyroid Hormone Receptors beta/*metabolism , Triiodothyronine/*physiology, Adenoviridae/genetics ; Animals ; Base Sequence ; Cholesterol 7-alpha-Hydroxylase/metabolism ; Enzyme Induction ; Gene Expression ; HEK293 Cells ; Hep G2 Cells ; Humans ; Mice ; Promoter Regions, Genetic ; Protein Binding ; Thyroid Hormone Receptors beta/genetics

المؤلفون: Meruvu S; Center for Genomic Medicine, Houston Methodist Research Institute , Houston, Texas., Ayers SD, Winnier G, Webb P

المصدر: Thyroid : official journal of the American Thyroid Association [Thyroid] 2013 Nov; Vol. 23 (11), pp. 1333-44. Date of Electronic Publication: 2013 Oct 16.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Mary Ann Liebert Publishers Country of Publication: United States NLM ID: 9104317 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-9077 (Electronic) Linking ISSN: 10507256 NLM ISO Abbreviation: Thyroid Subsets: MEDLINE

مواضيع طبية MeSH: Antithyroid Agents/*chemistry , Receptors, Thyroid Hormone/*metabolism , Thyroid Hormones/*chemistry, Animals ; Chemistry, Pharmaceutical/trends ; Cholesterol/metabolism ; Clinical Trials as Topic ; Drug Design ; Fatty Liver/metabolism ; Glucose/metabolism ; Homeostasis ; Humans ; Hydroxymethylglutaryl-CoA Reductase Inhibitors/metabolism ; Lipids/chemistry ; Metabolic Syndrome/metabolism ; Non-alcoholic Fatty Liver Disease ; Obesity/metabolism ; Signal Transduction ; Thyroid Hormone Receptors beta/metabolism

المؤلفون: Bernardes A; Institute of Physics of São Carlos, University of São Paulo, Avenida Trabalhador Sãocarlense 400, São Carlos, SP 13560-970, Brazil., Souza PC, Muniz JR, Ricci CG, Ayers SD, Parekh NM, Godoy AS, Trivella DB, Reinach P, Webb P, Skaf MS, Polikarpov I

المصدر: Journal of molecular biology [J Mol Biol] 2013 Aug 23; Vol. 425 (16), pp. 2878-93. Date of Electronic Publication: 2013 May 21.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 2985088R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1089-8638 (Electronic) Linking ISSN: 00222836 NLM ISO Abbreviation: J Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: PPAR alpha/*agonists , PPAR alpha/*chemistry , Pyrimidines/*chemistry , Pyrimidines/*metabolism, Anti-Inflammatory Agents/chemistry ; Anti-Inflammatory Agents/metabolism ; Cells, Cultured ; Crystallography, X-Ray ; Dose-Response Relationship, Drug ; Humans ; Interleukin-6/metabolism ; Interleukin-8/metabolism ; Kinetics ; Models, Molecular ; Molecular Dynamics Simulation ; Protein Conformation

المؤلفون: Nandhikonda P; Department of Chemistry and Biochemistry, University of Wisconsin-Milwaukee, Milwaukee, Wisconsin 53211, USA., Yasgar A, Baranowski AM, Sidhu PS, McCallum MM, Pawlak AJ, Teske K, Feleke B, Yuan NY, Kevin C, Bikle DD, Ayers SD, Webb P, Rai G, Simeonov A, Jadhav A, Maloney D, Arnold LA

المصدر: Biochemistry [Biochemistry] 2013 Jun 18; Vol. 52 (24), pp. 4193-203. Date of Electronic Publication: 2013 Jun 10.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 0370623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4995 (Electronic) Linking ISSN: 00062960 NLM ISO Abbreviation: Biochemistry Subsets: MEDLINE

مواضيع طبية MeSH: Cell Nucleus/*metabolism , Nuclear Receptor Coactivator 2/*chemistry , PPAR delta/*agonists , Receptors, Calcitriol/*chemistry , Thiazoles/*pharmacology, Cell Line, Tumor ; DNA/chemistry ; Dose-Response Relationship, Drug ; HEK293 Cells ; HL-60 Cells ; Humans ; Inhibitory Concentration 50 ; Ligands ; Protein Binding ; Rhodamines/chemistry ; Spectrophotometry/methods

المؤلفون: Kohwi-Shigematsu T; Life Sciences Division, Lawrence Berkeley National Laboratory, University of California, Berkeley, CA 94720, USA. TKohwi-Shigematsu@lbl.gov, Kohwi Y, Takahashi K, Richards HW, Ayers SD, Han HJ, Cai S

المصدر: Methods (San Diego, Calif.) [Methods] 2012 Nov; Vol. 58 (3), pp. 243-54. Date of Electronic Publication: 2012 Jul 07.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.; Review

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 9426302 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9130 (Electronic) Linking ISSN: 10462023 NLM ISO Abbreviation: Methods Subsets: MEDLINE

مواضيع طبية MeSH: Chromatin/*genetics , Matrix Attachment Region Binding Proteins/*physiology, Animals ; Base Sequence ; Binding Sites ; Chromatin Immunoprecipitation/methods ; Chromosome Mapping/methods ; Cross-Linking Reagents/chemistry ; Formaldehyde/chemistry ; Humans ; Models, Molecular ; Molecular Sequence Data ; Nucleic Acid Conformation

المؤلفون: Amato AA; Laboratório de Farmacologia Molecular, Departamento de Ciências Farmacêuticas, Faculdade de Ciências da Saúde, Universidade de Brasília, 70919-970 Brazil., Rajagopalan S, Lin JZ, Carvalho BM, Figueira AC, Lu J, Ayers SD, Mottin M, Silveira RL, Souza PC, Mourão RH, Saad MJ, Togashi M, Simeoni LA, Abdalla DS, Skaf MS, Polikparpov I, Lima MC, Galdino SL, Brennan RG, Baxter JD, Pitta IR, Webb P, Phillips KJ, Neves FA

المصدر: The Journal of biological chemistry [J Biol Chem] 2012 Aug 10; Vol. 287 (33), pp. 28169-79. Date of Electronic Publication: 2012 May 14.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Inc. on behalf of American Society for Biochemistry and Molecular Biology Country of Publication: United States NLM ID: 2985121R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1083-351X (Electronic) Linking ISSN: 00219258 NLM ISO Abbreviation: J Biol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Weight Gain*, Hypoglycemic Agents/*pharmacology , PPAR gamma/*agonists , Thiazolidinediones/*pharmacology, 3T3-L1 Cells ; Animals ; Cyclin-Dependent Kinase 5/genetics ; Cyclin-Dependent Kinase 5/metabolism ; Drug Evaluation, Preclinical ; Humans ; Hypoglycemic Agents/chemistry ; Hypoglycemic Agents/pharmacokinetics ; Ligands ; Mice ; NIH 3T3 Cells ; PPAR gamma/genetics ; PPAR gamma/metabolism ; Phosphorylation/drug effects ; Phosphorylation/genetics ; Protein Structure, Secondary ; Thiazolidinediones/chemistry ; Thiazolidinediones/pharmacokinetics ; U937 Cells

المؤلفون: Puhl AC; Instituto de Física de São Carlos, Universidade de São Paulo, São Carlos, SP, Brazil., Bernardes A, Silveira RL, Yuan J, Campos JL, Saidemberg DM, Palma MS, Cvoro A, Ayers SD, Webb P, Reinach PS, Skaf MS, Polikarpov I

المصدر: Molecular pharmacology [Mol Pharmacol] 2012 Jun; Vol. 81 (6), pp. 788-99. Date of Electronic Publication: 2012 Mar 05.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society for Pharmacology and Experimental Therapeutics Country of Publication: United States NLM ID: 0035623 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1521-0111 (Electronic) Linking ISSN: 0026895X NLM ISO Abbreviation: Mol Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Luteolin/*pharmacology , PPAR gamma/*agonists, 3T3-L1 Cells ; Animals ; Base Sequence ; DNA Primers ; Gene Expression Regulation/drug effects ; Humans ; Luteolin/chemistry ; Mice ; Models, Molecular ; Molecular Dynamics Simulation ; Myristic Acid/chemistry ; PPAR gamma/chemistry ; PPAR gamma/genetics ; Real-Time Polymerase Chain Reaction ; Reverse Transcriptase Polymerase Chain Reaction ; Rosiglitazone ; Thiazolidinediones/antagonists & inhibitors ; Thiazolidinediones/pharmacology

المؤلفون: Liberato MV; São Carlos Physics Institute, University of São Paulo, São Carlos, Sao Paulo, Brazil., Nascimento AS, Ayers SD, Lin JZ, Cvoro A, Silveira RL, Martínez L, Souza PC, Saidemberg D, Deng T, Amato AA, Togashi M, Hsueh WA, Phillips K, Palma MS, Neves FA, Skaf MS, Webb P, Polikarpov I

المصدر: PloS one [PLoS One] 2012; Vol. 7 (5), pp. e36297. Date of Electronic Publication: 2012 May 23.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Models, Molecular* , Protein Conformation*, Fatty Acids/*metabolism , PPAR gamma/*chemistry , PPAR gamma/*metabolism , Thiazolidinediones/*metabolism, 3T3 Cells ; Animals ; Azo Compounds ; Crystallization ; Fatty Acids/pharmacology ; HeLa Cells ; Humans ; Mice ; Molecular Dynamics Simulation ; PPAR gamma/agonists ; Protein Structure, Tertiary