المؤلفون: Saulnier O; INSERM U830, Équipe Labellisée LNCC, PSL Research University, SIREDO Oncology Centre, Institut Curie, 75005 Paris, France.; Université Paris Diderot, Sorbonne Paris Cité, F-75013 Paris, France., Guedri-Idjouadiene K; University of Liège, Interdisciplinary Cluster for Applied Genoproteomics (GIGA), Liège, Belgium.; University of Liège, GIGA-Molecular Biology of Diseases, Liège, Belgium., Aynaud MM; INSERM U830, Équipe Labellisée LNCC, PSL Research University, SIREDO Oncology Centre, Institut Curie, 75005 Paris, France., Chakraborty A; Institut Curie, PSL Research University, CNRS UMR3348, INSERM U1278, F-91405 Orsay, France.; Université Paris-Saclay, CNRS UMR3348, INSERM U1278, F-91405 Orsay, France.; Équipe Labellisée Ligue Nationale Contre le Cancer, F-91405 Orsay, France., Bruyr J; University of Liège, Interdisciplinary Cluster for Applied Genoproteomics (GIGA), Liège, Belgium.; University of Liège, GIGA-Molecular Biology of Diseases, Liège, Belgium., Pineau J; INSERM U830, Équipe Labellisée LNCC, PSL Research University, SIREDO Oncology Centre, Institut Curie, 75005 Paris, France., O'Grady T; University of Liège, Interdisciplinary Cluster for Applied Genoproteomics (GIGA), Liège, Belgium.; University of Liège, GIGA-Molecular Biology of Diseases, Liège, Belgium., Mirabeau O; INSERM U830, Équipe Labellisée LNCC, PSL Research University, SIREDO Oncology Centre, Institut Curie, 75005 Paris, France., Grossetête S; INSERM U830, Équipe Labellisée LNCC, PSL Research University, SIREDO Oncology Centre, Institut Curie, 75005 Paris, France., Galvan B; University of Liège, Interdisciplinary Cluster for Applied Genoproteomics (GIGA), Liège, Belgium.; University of Liège, GIGA-Molecular Biology of Diseases, Liège, Belgium., Claes M; University of Liège, Interdisciplinary Cluster for Applied Genoproteomics (GIGA), Liège, Belgium.; University of Liège, GIGA-Molecular Biology of Diseases, Liège, Belgium., Al Oula Hassoun Z; University of Liège, Interdisciplinary Cluster for Applied Genoproteomics (GIGA), Liège, Belgium.; University of Liège, GIGA-Molecular Biology of Diseases, Liège, Belgium., Sadacca B; INSERM U932, RT2Lab Team, Translational Research Department, PSL Research University, Institut Curie, F-75005 Paris, France.; CNRS UMR5219, Institut de Mathématiques de Toulouse; Université de Toulouse; F-31062 Toulouse, France., Laud K; INSERM U830, Équipe Labellisée LNCC, PSL Research University, SIREDO Oncology Centre, Institut Curie, 75005 Paris, France., Zaïdi S; INSERM U830, Équipe Labellisée LNCC, PSL Research University, SIREDO Oncology Centre, Institut Curie, 75005 Paris, France., Surdez D; INSERM U830, Équipe Labellisée LNCC, PSL Research University, SIREDO Oncology Centre, Institut Curie, 75005 Paris, France., Baulande S; Institut Curie, PSL Research University, NGS Platform, 26 rue d'Ulm, F-75005 Paris, France., Rambout X; University of Liège, Interdisciplinary Cluster for Applied Genoproteomics (GIGA), Liège, Belgium.; University of Liège, GIGA-Molecular Biology of Diseases, Liège, Belgium., Tirode F; Claude Bernard University Lyon 1, INSERM 1052, CNRS 5286, Cancer Research Center of Lyon (CRCL), Lyon University, Lyon, France., Dutertre M; Institut Curie, PSL Research University, CNRS UMR3348, INSERM U1278, F-91405 Orsay, France.; Université Paris-Saclay, CNRS UMR3348, INSERM U1278, F-91405 Orsay, France.; Équipe Labellisée Ligue Nationale Contre le Cancer, F-91405 Orsay, France., Delattre O; INSERM U830, Équipe Labellisée LNCC, PSL Research University, SIREDO Oncology Centre, Institut Curie, 75005 Paris, France., Dequiedt F; University of Liège, Interdisciplinary Cluster for Applied Genoproteomics (GIGA), Liège, Belgium.; University of Liège, GIGA-Molecular Biology of Diseases, Liège, Belgium.

المصدر: Nucleic acids research [Nucleic Acids Res] 2021 May 21; Vol. 49 (9), pp. 5038-5056.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

مواضيع طبية MeSH: Alternative Splicing*, Oncogene Proteins, Fusion/*metabolism , Proto-Oncogene Protein c-fli-1/*metabolism , RNA Splicing Factors/*metabolism , RNA-Binding Protein EWS/*metabolism , Repressor Proteins/*metabolism, Calmodulin-Binding Proteins/genetics ; Calmodulin-Binding Proteins/metabolism ; Cell Line ; Cell Line, Tumor ; HeLa Cells ; Human Umbilical Vein Endothelial Cells/metabolism ; Humans ; Protein Domains ; Sarcoma, Ewing/genetics ; Sarcoma, Ewing/metabolism ; Transcriptional Regulator ERG/chemistry ; Transcriptional Regulator ERG/metabolism

المؤلفون: Pearson JD; Lunenfeld-Tanenbaum Research Institute, Mt Sinai Hospital, Sinai Health System, Toronto, Canada.; Department of Ophthalmology and Vision Science, University of Toronto, Toronto, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada., Trcka D; Lunenfeld-Tanenbaum Research Institute, Mt Sinai Hospital, Sinai Health System, Toronto, Canada., Lu S; Lunenfeld-Tanenbaum Research Institute, Mt Sinai Hospital, Sinai Health System, Toronto, Canada.; Department of Ophthalmology and Vision Science, University of Toronto, Toronto, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada., Hyduk SJ; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada., Jen M; Lunenfeld-Tanenbaum Research Institute, Mt Sinai Hospital, Sinai Health System, Toronto, Canada.; Network Collaborative Biology Centre, Lunenfeld-Tanenbaum Research Institute, Mt Sinai Hospital, Toronto, Canada., Aynaud MM; Lunenfeld-Tanenbaum Research Institute, Mt Sinai Hospital, Sinai Health System, Toronto, Canada., Hernández JJ; Lunenfeld-Tanenbaum Research Institute, Mt Sinai Hospital, Sinai Health System, Toronto, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Canada., Peidis P; Lunenfeld-Tanenbaum Research Institute, Mt Sinai Hospital, Sinai Health System, Toronto, Canada.; Department of Ophthalmology and Vision Science, University of Toronto, Toronto, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada., Barrios-Rodiles M; Lunenfeld-Tanenbaum Research Institute, Mt Sinai Hospital, Sinai Health System, Toronto, Canada.; Network Collaborative Biology Centre, Lunenfeld-Tanenbaum Research Institute, Mt Sinai Hospital, Toronto, Canada., Chan K; Lunenfeld-Tanenbaum Research Institute, Mt Sinai Hospital, Sinai Health System, Toronto, Canada., Woodgett J; Lunenfeld-Tanenbaum Research Institute, Mt Sinai Hospital, Sinai Health System, Toronto, Canada.; Department of Medical Biophysics, University of Toronto, Toronto, Canada., Mazzulli T; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada.; Department of Microbiology, Sinai Health System/University Health Network, Toronto, Canada., Attisano L; Department of Biochemistry, Donnelly Centre, University of Toronto, Toronto, Canada., Pelletier L; Lunenfeld-Tanenbaum Research Institute, Mt Sinai Hospital, Sinai Health System, Toronto, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Canada., Cybulsky MI; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada.; Toronto General Hospital Research Institute, University Health Network, Toronto, Canada., Wrana JL; Lunenfeld-Tanenbaum Research Institute, Mt Sinai Hospital, Sinai Health System, Toronto, Canada.; Network Collaborative Biology Centre, Lunenfeld-Tanenbaum Research Institute, Mt Sinai Hospital, Toronto, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, Canada., Bremner R; Lunenfeld-Tanenbaum Research Institute, Mt Sinai Hospital, Sinai Health System, Toronto, Canada. bremner@lunenfeld.ca.; Department of Ophthalmology and Vision Science, University of Toronto, Toronto, Canada. bremner@lunenfeld.ca.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, Canada. bremner@lunenfeld.ca.

المصدر: Virology journal [Virol J] 2021 May 17; Vol. 18 (1), pp. 99. Date of Electronic Publication: 2021 May 17.

نوع المنشور: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 101231645 Publication Model: Electronic Cited Medium: Internet ISSN: 1743-422X (Electronic) Linking ISSN: 1743422X NLM ISO Abbreviation: Virol J Subsets: MEDLINE

مواضيع طبية MeSH: Reagent Kits, Diagnostic*, COVID-19/*diagnosis , COVID-19 Nucleic Acid Testing/*methods , SARS-CoV-2/*isolation & purification , Specimen Handling/*methods, Humans ; Nasopharynx/virology ; RNA, Viral/isolation & purification ; Sensitivity and Specificity

المؤلفون: Aynaud MM; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, M5G 1X5, ON, Canada., Hernandez JJ; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, M5G 1X5, ON, Canada.; Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, M5S 3E1, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, M5S 1A8, ON, Canada., Barutcu S; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, M5G 1X5, ON, Canada., Braunschweig U; Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, M5S 3E1, ON, Canada., Chan K; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, M5G 1X5, ON, Canada., Pearson JD; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, M5G 1X5, ON, Canada., Trcka D; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, M5G 1X5, ON, Canada., Prosser SL; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, M5G 1X5, ON, Canada., Kim J; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, M5G 1X5, ON, Canada., Barrios-Rodiles M; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, M5G 1X5, ON, Canada., Jen M; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, M5G 1X5, ON, Canada., Song S; Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, M5S 3E1, ON, Canada.; Department of Biochemistry, University of Toronto, Toronto, M5S 1A8, ON, Canada., Shen J; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, M5G 1X5, ON, Canada., Bruce C; Department of Microbiology, Mount Sinai Hospital/University Health Network, Toronto, M5G 1X5, ON, Canada., Hazlett B; Department of Microbiology, Mount Sinai Hospital/University Health Network, Toronto, M5G 1X5, ON, Canada., Poutanen S; Department of Microbiology, Mount Sinai Hospital/University Health Network, Toronto, M5G 1X5, ON, Canada., Attisano L; Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, M5S 3E1, ON, Canada.; Department of Biochemistry, University of Toronto, Toronto, M5S 1A8, ON, Canada., Bremner R; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, M5G 1X5, ON, Canada., Blencowe BJ; Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, M5S 3E1, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, M5S 1A8, ON, Canada., Mazzulli T; Department of Microbiology, Mount Sinai Hospital/University Health Network, Toronto, M5G 1X5, ON, Canada., Han H; Donnelly Centre for Cellular and Biomolecular Research, University of Toronto, Toronto, M5S 3E1, ON, Canada., Pelletier L; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, M5G 1X5, ON, Canada. pelletier@lunenfeld.ca.; Department of Molecular Genetics, University of Toronto, Toronto, M5S 1A8, ON, Canada. pelletier@lunenfeld.ca., Wrana JL; Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, Toronto, M5G 1X5, ON, Canada. wrana@lunenfeld.ca.; Department of Molecular Genetics, University of Toronto, Toronto, M5S 1A8, ON, Canada. wrana@lunenfeld.ca.

المصدر: Nature communications [Nat Commun] 2021 Mar 03; Vol. 12 (1), pp. 1405. Date of Electronic Publication: 2021 Mar 03.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: High-Throughput Nucleotide Sequencing/*methods , SARS-CoV-2/*growth & development , SARS-CoV-2/*pathogenicity, COVID-19/genetics ; COVID-19/immunology ; COVID-19/virology ; Humans ; Molecular Diagnostic Techniques ; Nucleic Acid Amplification Techniques ; RNA, Viral/genetics ; Reverse Transcriptase Polymerase Chain Reaction ; Viral Load

المؤلفون: Aynaud MM; INSERM U830, Équipe Labellisée LNCC, SIREDO Oncology Centre, Institut Curie, 75005 Paris, France., Mirabeau O; INSERM U830, Équipe Labellisée LNCC, SIREDO Oncology Centre, Institut Curie, 75005 Paris, France., Gruel N; INSERM U830, Équipe Labellisée LNCC, SIREDO Oncology Centre, Institut Curie, 75005 Paris, France; Institut Curie, PSL Research University, Department of Translational Research, 75005 Paris, France., Grossetête S; INSERM U830, Équipe Labellisée LNCC, SIREDO Oncology Centre, Institut Curie, 75005 Paris, France., Boeva V; Institut Cochin, INSERM U1016, CNRS UMR 8104, Université Paris Descartes UMR-S1016, 75014 Paris, France; Department of Computer Science, Institute for Machine Learning, Swiss Institute of Bioinformatics (SIB), ETH Zurich, 8092 Zurich, Switzerland; INSERM U900, 75005 Paris, France; Mines ParisTech, PSL Research University, CBIO-Centre for Computational Biology, 75006 Paris, France; Institut Curie, PSL Research University, 75005 Paris, France., Durand S; INSERM U830, Équipe Labellisée LNCC, SIREDO Oncology Centre, Institut Curie, 75005 Paris, France., Surdez D; INSERM U830, Équipe Labellisée LNCC, SIREDO Oncology Centre, Institut Curie, 75005 Paris, France., Saulnier O; INSERM U830, Équipe Labellisée LNCC, SIREDO Oncology Centre, Institut Curie, 75005 Paris, France., Zaïdi S; INSERM U830, Équipe Labellisée LNCC, SIREDO Oncology Centre, Institut Curie, 75005 Paris, France., Gribkova S; INSERM U900, 75005 Paris, France; Mines ParisTech, PSL Research University, CBIO-Centre for Computational Biology, 75006 Paris, France; Institut Curie, PSL Research University, 75005 Paris, France; Université Denis Diderot, 75013, Paris, France., Fouché A; École Normale Supérieure Paris-Saclay, 94230 Cachan, France., Kairov U; Laboratory of Bioinformatics and Systems Biology, Center for Life Sciences, National Laboratory Astana, Nazarbayev University, Nur-Sultan, Kazakhstan., Raynal V; INSERM U830, Équipe Labellisée LNCC, SIREDO Oncology Centre, Institut Curie, 75005 Paris, France., Tirode F; University of Lyon, Université Claude Bernard Lyon 1, CNRS 5286, INSERM U1052, Cancer Research Centre of Lyon, 69008 Lyon, France., Grünewald TGP; INSERM U830, Équipe Labellisée LNCC, SIREDO Oncology Centre, Institut Curie, 75005 Paris, France; Institut Curie, PSL Research University, Department of Translational Research, 75005 Paris, France., Bohec M; NGS Platform, Institut Curie, 75005 Paris, France., Baulande S; NGS Platform, Institut Curie, 75005 Paris, France., Janoueix-Lerosey I; INSERM U830, Équipe Labellisée LNCC, SIREDO Oncology Centre, Institut Curie, 75005 Paris, France., Vert JP; Mines ParisTech, PSL Research University, CBIO-Centre for Computational Biology, 75006 Paris, France; Google Research, Brain Team, 75009 Paris, France., Barillot E; INSERM U900, 75005 Paris, France; Mines ParisTech, PSL Research University, CBIO-Centre for Computational Biology, 75006 Paris, France; Institut Curie, PSL Research University, 75005 Paris, France., Delattre O; INSERM U830, Équipe Labellisée LNCC, SIREDO Oncology Centre, Institut Curie, 75005 Paris, France. Electronic address: olivier.delattre@curie.fr., Zinovyev A; INSERM U900, 75005 Paris, France; Mines ParisTech, PSL Research University, CBIO-Centre for Computational Biology, 75006 Paris, France; Institut Curie, PSL Research University, 75005 Paris, France. Electronic address: andrei.zinovyev@curie.fr.

المصدر: Cell reports [Cell Rep] 2020 Feb 11; Vol. 30 (6), pp. 1767-1779.e6.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation, Neoplastic/*genetics , RNA-Binding Protein EWS/*metabolism , Sarcoma, Ewing/*genetics , Transcription, Genetic/*genetics, Cell Line, Tumor ; Humans ; Signal Transduction

المؤلفون: Musa J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany., Cidre-Aranaz F; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany., Aynaud MM; INSERM U830, Équipe Labellisée LNCC Genetics and Biology of Pediatric Cancers, PSL Research University, SIREDO Oncology Centre, Institut Curie Research Centre, Paris, France., Orth MF; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany., Knott MML; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany., Mirabeau O; INSERM U830, Équipe Labellisée LNCC Genetics and Biology of Pediatric Cancers, PSL Research University, SIREDO Oncology Centre, Institut Curie Research Centre, Paris, France., Mazor G; Department of Life Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel., Varon M; Department of Life Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel., Hölting TLB; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany., Grossetête S; INSERM U830, Équipe Labellisée LNCC Genetics and Biology of Pediatric Cancers, PSL Research University, SIREDO Oncology Centre, Institut Curie Research Centre, Paris, France., Gartlgruber M; Neuroblastoma Genomics, German Cancer Research Center (DKFZ), Heidelberg, Germany., Surdez D; INSERM U830, Équipe Labellisée LNCC Genetics and Biology of Pediatric Cancers, PSL Research University, SIREDO Oncology Centre, Institut Curie Research Centre, Paris, France., Gerke JS; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany., Ohmura S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany., Marchetto A; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany., Dallmayer M; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany., Baldauf MC; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany., Stein S; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany., Sannino G; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany., Li J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany., Romero-Pérez L; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany., Westermann F; Neuroblastoma Genomics, German Cancer Research Center (DKFZ), Heidelberg, Germany., Hartmann W; Division of Translational Pathology, Gerhard-Domagk Institute of Pathology, University Hospital of Münster, Münster, Germany., Dirksen U; Department of Pediatric Hematology and Oncology, University Hospital of Essen, Essen, Germany., Gymrek M; Department of Medicine, University of California, San Diego, La Jolla, CA, USA.; Department of Computer Science and Engineering, University of California, San Diego, La Jolla, CA, USA., Anderson ND; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada., Shlien A; Program in Genetics and Genome Biology, The Hospital for Sick Children, Toronto, ON, Canada.; Department of Laboratory Medicine and Pathobiology, University of Toronto, Toronto, ON, Canada.; Department of Paediatric Laboratory Medicine, The Hospital for Sick Children, Toronto, ON, Canada., Rotblat B; Department of Life Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel., Kirchner T; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany.; German Cancer Consortium (DKTK), Partner site Munich, Munich, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany., Delattre O; INSERM U830, Équipe Labellisée LNCC Genetics and Biology of Pediatric Cancers, PSL Research University, SIREDO Oncology Centre, Institut Curie Research Centre, Paris, France., Grünewald TGP; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany. thomas.gruenewald@med.uni-muenchen.de.; Institute of Pathology, Faculty of Medicine, LMU Munich, Munich, Germany. thomas.gruenewald@med.uni-muenchen.de.; German Cancer Consortium (DKTK), Partner site Munich, Munich, Germany. thomas.gruenewald@med.uni-muenchen.de.; German Cancer Research Center (DKFZ), Heidelberg, Germany. thomas.gruenewald@med.uni-muenchen.de.

المصدر: Nature communications [Nat Commun] 2019 Sep 11; Vol. 10 (1), pp. 4128. Date of Electronic Publication: 2019 Sep 11.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Germ-Line Mutation/*genetics , Neoplasms/*genetics , Neoplasms/*therapy, Animals ; Cell Cycle Proteins ; Cell Line, Tumor ; Cell Proliferation ; Cell Survival ; Cyclin-Dependent Kinase 2/antagonists & inhibitors ; Cyclin-Dependent Kinase 2/metabolism ; Gene Expression Regulation, Neoplastic ; HEK293 Cells ; Humans ; Mice ; Microsatellite Repeats/genetics ; Neoplasm Proteins/metabolism ; Oncogene Proteins, Fusion/metabolism ; Phenotype ; Polymorphism, Genetic ; Trans-Activators ; Treatment Outcome ; Up-Regulation/genetics

المؤلفون: Chauvin C; Paris-Sciences-Lettres Research University, Institut Curie Research Center, SiRIC, Laboratory of Translational Research in Pediatric Oncology, Paris 75005, France; Paris-Sciences-Lettres Research University, Institut Curie Research Center, INSERM U830, Laboratory of Biology and Genetics of Cancers, Paris 75005, France., Leruste A; Paris-Sciences-Lettres Research University, Institut Curie Research Center, SiRIC, Laboratory of Translational Research in Pediatric Oncology, Paris 75005, France; Paris-Sciences-Lettres Research University, Institut Curie Research Center, INSERM U830, Laboratory of Biology and Genetics of Cancers, Paris 75005, France., Tauziede-Espariat A; Sainte-Anne Hospital, Department of Neuropathology, Paris 75005, France., Andrianteranagna M; Paris-Sciences-Lettres Research University, Institut Curie Research Center, SiRIC, Laboratory of Translational Research in Pediatric Oncology, Paris 75005, France; Paris-Sciences-Lettres Research University, Institut Curie Research Center, INSERM U830, Laboratory of Biology and Genetics of Cancers, Paris 75005, France., Surdez D; Paris-Sciences-Lettres Research University, Institut Curie Research Center, INSERM U830, Laboratory of Biology and Genetics of Cancers, Paris 75005, France., Lescure A; Paris-Sciences-Lettres Research University, Institut Curie, Department of Translational Research, the Biophenics High-Content Screening Laboratory, Cell and Tissue Imaging Facility (PICT-IBiSA), Paris 75005, France., Han ZY; Paris-Sciences-Lettres Research University, Institut Curie Research Center, SiRIC, Laboratory of Translational Research in Pediatric Oncology, Paris 75005, France; Paris-Sciences-Lettres Research University, Institut Curie Research Center, INSERM U830, Laboratory of Biology and Genetics of Cancers, Paris 75005, France., Anthony E; Paris-Sciences-Lettres Research University, Institut Curie, Department of Translational Research, the Biophenics High-Content Screening Laboratory, Cell and Tissue Imaging Facility (PICT-IBiSA), Paris 75005, France., Richer W; Paris-Sciences-Lettres Research University, Institut Curie Research Center, SiRIC, Laboratory of Translational Research in Pediatric Oncology, Paris 75005, France; Paris-Sciences-Lettres Research University, Institut Curie Research Center, INSERM U830, Laboratory of Biology and Genetics of Cancers, Paris 75005, France., Baulande S; Paris-Sciences-Lettres Research University, Institut Curie, Next Generation Sequencing Platform, Paris 75005, France., Bohec M; Paris-Sciences-Lettres Research University, Institut Curie, Next Generation Sequencing Platform, Paris 75005, France., Zaidi S; Paris-Sciences-Lettres Research University, Institut Curie Research Center, INSERM U830, Laboratory of Biology and Genetics of Cancers, Paris 75005, France., Aynaud MM; Paris-Sciences-Lettres Research University, Institut Curie Research Center, INSERM U830, Laboratory of Biology and Genetics of Cancers, Paris 75005, France., Maillot L; Paris-Sciences-Lettres Research University, Institut Curie, Laboratory of Somatic Genetics, Paris 75005, France., Masliah-Planchon J; Paris-Sciences-Lettres Research University, Institut Curie, Laboratory of Somatic Genetics, Paris 75005, France., Cairo S; LTTA Center, Department of Morphology, Surgery and Experimental Medicine, University of Ferrara, Ferrara 44121, Italy; XenTech, Evry 91000, France., Roman-Roman S; Paris-Sciences-Lettres Research University, Institut Curie, Department of Translational Research, the Biophenics High-Content Screening Laboratory, Cell and Tissue Imaging Facility (PICT-IBiSA), Paris 75005, France., Delattre O; Paris-Sciences-Lettres Research University, Institut Curie Research Center, SiRIC, Laboratory of Translational Research in Pediatric Oncology, Paris 75005, France; Paris-Sciences-Lettres Research University, Institut Curie Research Center, INSERM U830, Laboratory of Biology and Genetics of Cancers, Paris 75005, France; Paris-Sciences-Lettres Research University, Institut Curie, Laboratory of Somatic Genetics, Paris 75005, France., Del Nery E; Paris-Sciences-Lettres Research University, Institut Curie, Department of Translational Research, the Biophenics High-Content Screening Laboratory, Cell and Tissue Imaging Facility (PICT-IBiSA), Paris 75005, France., Bourdeaut F; Paris-Sciences-Lettres Research University, Institut Curie Research Center, SiRIC, Laboratory of Translational Research in Pediatric Oncology, Paris 75005, France; Paris-Sciences-Lettres Research University, Institut Curie Research Center, INSERM U830, Laboratory of Biology and Genetics of Cancers, Paris 75005, France; Paris-Sciences-Lettres Research University, Institut Curie Hospital, Department of Pediatric Oncology- Adolescents and Young Adults, Paris 75005, France. Electronic address: franck.bourdeaut@curie.fr.

المصدر: Cell reports [Cell Rep] 2017 Nov 14; Vol. 21 (7), pp. 1737-1745.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101573691 Publication Model: Print Cited Medium: Internet ISSN: 2211-1247 (Electronic) NLM ISO Abbreviation: Cell Rep Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Drug Discovery/*methods , High-Throughput Screening Assays/*methods , Protein Kinase Inhibitors/*pharmacology , Pyrimidines/*pharmacology , Quaternary Ammonium Compounds/*pharmacology , Rhabdoid Tumor/*metabolism , Sulfonamides/*pharmacology, Apoptosis/drug effects ; Cell Line, Tumor ; Endoplasmic Reticulum Stress/drug effects ; Humans ; Indazoles ; Receptor, Platelet-Derived Growth Factor alpha/antagonists & inhibitors ; Receptor, Platelet-Derived Growth Factor beta/antagonists & inhibitors ; SMARCB1 Protein/metabolism

المؤلفون: Musa J; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute for Pathology of the LMU Munich, Munich, Germany., Aynaud MM; INSERM Unit 830 'Genetics and Biology of Cancers', Institut Curie Research Center, Paris, France., Mirabeau O; INSERM Unit 830 'Genetics and Biology of Cancers', Institut Curie Research Center, Paris, France., Delattre O; INSERM Unit 830 'Genetics and Biology of Cancers', Institut Curie Research Center, Paris, France., Grünewald TG; Max-Eder Research Group for Pediatric Sarcoma Biology, Institute for Pathology of the LMU Munich, Munich, Germany.; German Cancer Consortium (DKTK), Munich, Germany.; German Cancer Research Center (DKFZ), Heidelberg, Germany.

المصدر: Cell death & disease [Cell Death Dis] 2017 Jun 22; Vol. 8 (6), pp. e2895. Date of Electronic Publication: 2017 Jun 22.

نوع المنشور: Journal Article; Review; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE

مواضيع طبية MeSH: Cell Differentiation*, Carcinogenesis/*metabolism , Carcinogenesis/*pathology , Trans-Activators/*metabolism, Animals ; Cell Cycle ; Cell Proliferation ; Cell Survival ; Humans

المؤلفون: Grünewald TG; Genetics and Biology of Cancers Unit, Institut Curie, PSL Research University, Paris, France.; INSERM U830, Institut Curie Research Center, Paris, France., Bernard V; Institut Curie Genomics of Excellence (ICGex) Platform, Institut Curie Research Center, Paris, France., Gilardi-Hebenstreit P; École Normale Supérieure (ENS), Institut de Biologie de l'ENS (IBENS), INSERM U1024, CNRS UMR8197, Paris, France., Raynal V; Genetics and Biology of Cancers Unit, Institut Curie, PSL Research University, Paris, France.; INSERM U830, Institut Curie Research Center, Paris, France.; Institut Curie Genomics of Excellence (ICGex) Platform, Institut Curie Research Center, Paris, France., Surdez D; Genetics and Biology of Cancers Unit, Institut Curie, PSL Research University, Paris, France.; INSERM U830, Institut Curie Research Center, Paris, France., Aynaud MM; Genetics and Biology of Cancers Unit, Institut Curie, PSL Research University, Paris, France.; INSERM U830, Institut Curie Research Center, Paris, France., Mirabeau O; Genetics and Biology of Cancers Unit, Institut Curie, PSL Research University, Paris, France.; INSERM U830, Institut Curie Research Center, Paris, France., Cidre-Aranaz F; Instituto de Investigación de Enfermedades Raras, Instituto de Salud Carlos III, Madrid, Spain., Tirode F; Genetics and Biology of Cancers Unit, Institut Curie, PSL Research University, Paris, France.; INSERM U830, Institut Curie Research Center, Paris, France., Zaidi S; Genetics and Biology of Cancers Unit, Institut Curie, PSL Research University, Paris, France.; INSERM U830, Institut Curie Research Center, Paris, France., Perot G; INSERM U916 Biology of Sarcomas, Institut Bergonié, Bordeaux, France., Jonker AH; Genetics and Biology of Cancers Unit, Institut Curie, PSL Research University, Paris, France.; INSERM U830, Institut Curie Research Center, Paris, France., Lucchesi C; Genetics and Biology of Cancers Unit, Institut Curie, PSL Research University, Paris, France.; INSERM U830, Institut Curie Research Center, Paris, France., Le Deley MC; Département d'Epidémiologie et de Biostatistiques, Institut Gustave Roussy, Villejuif, France., Oberlin O; Département de Pédiatrie, Institut Gustave Roussy, Villejuif, France., Marec-Bérard P; Institute for Pediatric Hematology and Oncology, Leon-Bérard Cancer Center, University of Lyon, Lyon, France., Véron AS; INSERM U1052, Léon-Bérard Cancer Centre, Cancer Research Center of Lyon, Lyon, France., Reynaud S; Unité Génétique Somatique (UGS), Institut Curie Centre Hospitalier, Paris, France., Lapouble E; Unité Génétique Somatique (UGS), Institut Curie Centre Hospitalier, Paris, France., Boeva V; INSERM U900, Bioinformatics, Biostatistics, Epidemiology and Computational Systems Biology of Cancer, Institut Curie Research Center, Paris, France.; Mines ParisTech, Fontainebleau, France., Rio Frio T; Institut Curie Genomics of Excellence (ICGex) Platform, Institut Curie Research Center, Paris, France., Alonso J; Instituto de Investigación de Enfermedades Raras, Instituto de Salud Carlos III, Madrid, Spain., Bhatia S; Institute for Cancer Outcomes and Survivorship, School of Medicine, University of Alabama, Birmingham, Alabama, USA., Pierron G; Unité Génétique Somatique (UGS), Institut Curie Centre Hospitalier, Paris, France., Cancel-Tassin G; Centre de Recherche sur les Pathologies Prostatiques (CeRePP)-Laboratory for Urology, Research Team 2, UPMC, Hôpital Tenon, Paris, France., Cussenot O; Centre de Recherche sur les Pathologies Prostatiques (CeRePP)-Laboratory for Urology, Research Team 2, UPMC, Hôpital Tenon, Paris, France., Cox DG; INSERM U1052, Léon-Bérard Cancer Centre, Cancer Research Center of Lyon, Lyon, France., Morton LM; Division of Cancer Epidemiology and Genetics (DCEG), National Cancer Institute (NCI), Bethesda, Maryland, USA., Machiela MJ; Division of Cancer Epidemiology and Genetics (DCEG), National Cancer Institute (NCI), Bethesda, Maryland, USA., Chanock SJ; Division of Cancer Epidemiology and Genetics (DCEG), National Cancer Institute (NCI), Bethesda, Maryland, USA., Charnay P; École Normale Supérieure (ENS), Institut de Biologie de l'ENS (IBENS), INSERM U1024, CNRS UMR8197, Paris, France., Delattre O; Genetics and Biology of Cancers Unit, Institut Curie, PSL Research University, Paris, France.; INSERM U830, Institut Curie Research Center, Paris, France.; Institut Curie Genomics of Excellence (ICGex) Platform, Institut Curie Research Center, Paris, France.; Unité Génétique Somatique (UGS), Institut Curie Centre Hospitalier, Paris, France.

المصدر: Nature genetics [Nat Genet] 2015 Sep; Vol. 47 (9), pp. 1073-8. Date of Electronic Publication: 2015 Jul 27.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE

مواضيع طبية MeSH: Bone Neoplasms/*genetics , Early Growth Response Protein 2/*genetics , Oncogene Proteins, Fusion/*genetics , Proto-Oncogene Protein c-fli-1/*genetics , RNA-Binding Protein EWS/*genetics , Sarcoma, Ewing/*genetics, Animals ; Base Sequence ; Bone Neoplasms/pathology ; Carotenoids/genetics ; Cell Line, Tumor ; Cell Proliferation ; Gene Expression ; Gene Expression Regulation, Neoplastic ; Genetic Association Studies ; Genetic Predisposition to Disease ; Humans ; Mice, SCID ; Microsatellite Repeats ; Molecular Sequence Data ; Neoplasm Transplantation ; Oxygenases/genetics ; Polymorphism, Single Nucleotide ; Quantitative Trait Loci ; Sarcoma, Ewing/pathology ; Tumor Burden

المؤلفون: Mussil B; Molecular Retrovirology Unit, Institut Pasteur, Paris, France., Suspène R, Aynaud MM, Gauvrit A, Vartanian JP, Wain-Hobson S

المصدر: PloS one [PLoS One] 2013 Aug 20; Vol. 8 (8), pp. e73641. Date of Electronic Publication: 2013 Aug 20 (Print Publication: 2013).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: DNA Breaks, Double-Stranded* , Stress, Physiological*, Cell Nucleus/*metabolism , Cytidine Deaminase/*metabolism , Proteins/*metabolism, Base Sequence ; CD4-Positive T-Lymphocytes/immunology ; Cell Cycle Checkpoints ; Cell Death ; Cytidine Deaminase/genetics ; HeLa Cells ; Histones/metabolism ; Humans ; Lymphocyte Activation ; Molecular Sequence Data ; Protein Isoforms/genetics ; Protein Isoforms/metabolism ; Protein Transport ; Proteins/genetics ; RNA Editing/genetics ; Signal Transduction/genetics ; Uracil-DNA Glycosidase/metabolism

المؤلفون: Suspène R; Molecular Retrovirology Unit, Institut Pasteur, Paris, France., Aynaud MM, Vartanian JP, Wain-Hobson S

المصدر: PloS one [PLoS One] 2013 Jun 20; Vol. 8 (6), pp. e63461. Date of Electronic Publication: 2013 Jun 20 (Print Publication: 2013).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: Electronic-Print Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Cytidine/*analogs & derivatives , Cytidine Deaminase/*chemistry , DNA, Single-Stranded/*chemistry , Proteins/*chemistry, Animals ; Base Sequence ; Cell Line ; CpG Islands ; Cytidine/chemistry ; Cytidine/metabolism ; Cytidine Deaminase/metabolism ; DNA, Viral/genetics ; DNA, Viral/metabolism ; Deamination ; Genes, p53 ; HEK293 Cells ; HIV-1/genetics ; Humans ; Molecular Sequence Data ; Oligodeoxyribonucleotides ; Proteins/metabolism ; Quail ; Substrate Specificity