المؤلفون: Chen W; Center of Clinical Pharmacology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China., Ruan Z; Center of Clinical Pharmacology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China., Lou H; Center of Clinical Pharmacology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China., Yang D; Center of Clinical Pharmacology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China., Chen J; Center of Clinical Pharmacology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China., Shao R; Center of Clinical Pharmacology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China., Jiang B; Center of Clinical Pharmacology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China. Electronic address: jiangbo@zju.edu.cn.

المصدر: European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences [Eur J Pharm Sci] 2023 Nov 01; Vol. 190, pp. 106576. Date of Electronic Publication: 2023 Sep 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science B.V Country of Publication: Netherlands NLM ID: 9317982 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0720 (Electronic) Linking ISSN: 09280987 NLM ISO Abbreviation: Eur J Pharm Sci Subsets: MEDLINE

مواضيع طبية MeSH: Azetines* , Anticholesteremic Agents*, Fluorobenzenes ; Fasting/metabolism ; Therapeutic Equivalency ; Cross-Over Studies ; Area Under Curve ; Healthy Volunteers

المؤلفون: Losa R; Université Paris-Saclay, CNRS, Institut de Chimie des Substances Naturelles, UPR 2301, 91198, Gif-sur-Yvette, France., Lorton C; Université Paris-Saclay, CNRS, Institut de Chimie des Substances Naturelles, UPR 2301, 91198, Gif-sur-Yvette, France., Retailleau P; Université Paris-Saclay, CNRS, Institut de Chimie des Substances Naturelles, UPR 2301, 91198, Gif-sur-Yvette, France., Bignon J; Université Paris-Saclay, CNRS, Institut de Chimie des Substances Naturelles, UPR 2301, 91198, Gif-sur-Yvette, France., Voituriez A; Université Paris-Saclay, CNRS, Institut de Chimie des Substances Naturelles, UPR 2301, 91198, Gif-sur-Yvette, France.

المصدر: Organic letters [Org Lett] 2023 Jul 14; Vol. 25 (27), pp. 5140-5144. Date of Electronic Publication: 2023 Jun 30.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 100890393 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1523-7052 (Electronic) Linking ISSN: 15237052 NLM ISO Abbreviation: Org Lett Subsets: MEDLINE

مواضيع طبية MeSH: Azetines* , Phosphines*, Humans ; Carboxylic Acids ; Catalysis ; Benzoates/chemistry

المؤلفون: Gatazka MR; Willard Henry Dow Laboratory, Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA. corinnas@umich.edu., McFee EC; Willard Henry Dow Laboratory, Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA. corinnas@umich.edu., Ng CH; Willard Henry Dow Laboratory, Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA. corinnas@umich.edu., Wearing ER; Willard Henry Dow Laboratory, Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA. corinnas@umich.edu., Schindler CS; Willard Henry Dow Laboratory, Department of Chemistry, University of Michigan, Ann Arbor, MI 48109, USA. corinnas@umich.edu.

المصدر: Organic & biomolecular chemistry [Org Biomol Chem] 2022 Nov 30; Vol. 20 (46), pp. 9052-9068. Date of Electronic Publication: 2022 Nov 30.

نوع المنشور: Journal Article; Review; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101154995 Publication Model: Electronic Cited Medium: Internet ISSN: 1477-0539 (Electronic) Linking ISSN: 14770520 NLM ISO Abbreviation: Org Biomol Chem Subsets: MEDLINE

مواضيع طبية MeSH: Azetines*, Cyclization ; Nitrogen

المؤلفون: Chen W; Center of Clinical Pharmacology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China., Ruan Z; Center of Clinical Pharmacology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China., Chen J; Center of Clinical Pharmacology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China., Yang D; Center of Clinical Pharmacology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China., Shao R; Center of Clinical Pharmacology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China., Lou H; Center of Clinical Pharmacology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China., Jiang B; Center of Clinical Pharmacology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, China.

المصدر: British journal of clinical pharmacology [Br J Clin Pharmacol] 2022 Jul; Vol. 88 (7), pp. 3153-3161. Date of Electronic Publication: 2022 Feb 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 7503323 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1365-2125 (Electronic) Linking ISSN: 03065251 NLM ISO Abbreviation: Br J Clin Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Azetines* , Models, Biological*, China ; Female ; Fluorobenzenes ; Healthy Volunteers ; Humans ; Male ; Randomized Controlled Trials as Topic

المؤلفون: Colella M; FLAME-Lab, Flow Chemistry and Microreactor Technology Laboratory, Department of Pharmacy - Drug Sciences, University of Bari 'A. Moro', Via E. Orabona 4, 70125 Bari, Italy., Musci P; FLAME-Lab, Flow Chemistry and Microreactor Technology Laboratory, Department of Pharmacy - Drug Sciences, University of Bari 'A. Moro', Via E. Orabona 4, 70125 Bari, Italy., Cannillo D; FLAME-Lab, Flow Chemistry and Microreactor Technology Laboratory, Department of Pharmacy - Drug Sciences, University of Bari 'A. Moro', Via E. Orabona 4, 70125 Bari, Italy., Spennacchio M; FLAME-Lab, Flow Chemistry and Microreactor Technology Laboratory, Department of Pharmacy - Drug Sciences, University of Bari 'A. Moro', Via E. Orabona 4, 70125 Bari, Italy., Aramini A; Department of Discovery, Dompé Farmaceutici S.p.A., Via Campo di Pile, L'Aquila 67100, Italy., Degennaro L; FLAME-Lab, Flow Chemistry and Microreactor Technology Laboratory, Department of Pharmacy - Drug Sciences, University of Bari 'A. Moro', Via E. Orabona 4, 70125 Bari, Italy., Luisi R; FLAME-Lab, Flow Chemistry and Microreactor Technology Laboratory, Department of Pharmacy - Drug Sciences, University of Bari 'A. Moro', Via E. Orabona 4, 70125 Bari, Italy.

المصدر: The Journal of organic chemistry [J Org Chem] 2021 Oct 15; Vol. 86 (20), pp. 13943-13954. Date of Electronic Publication: 2021 Jul 22.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 2985193R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-6904 (Electronic) Linking ISSN: 00223263 NLM ISO Abbreviation: J Org Chem Subsets: MEDLINE

مواضيع طبية MeSH: Azetidines* , Azetines*

المؤلفون: Pirahmadi N; Faculty of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran. Iran., Zarghi A; Faculty of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran. Iran., Salimi A; Department of Pharmacology and Toxicology, School of Pharmacy, Ardabil University of Medical Science, Ardabil. Iran., Arefi H; Faculty of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran. Iran., Pourahmad J; Toxicology and Pharmacology, Faculty of Pharmacy, Shahid Beheshti University of Medical Sciences, Tehran. Iran.

المصدر: Anti-cancer agents in medicinal chemistry [Anticancer Agents Med Chem] 2017; Vol. 17 (9), pp. 1292-1301.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Bentham Science Publishers Country of Publication: Netherlands NLM ID: 101265649 Publication Model: Print Cited Medium: Internet ISSN: 1875-5992 (Electronic) Linking ISSN: 18715206 NLM ISO Abbreviation: Anticancer Agents Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Antineoplastic Agents/*pharmacology , Azetines/*pharmacology , B-Lymphocytes/*drug effects , B-Lymphocytes/*pathology , Mitochondria/*drug effects , Precursor Cell Lymphoblastic Leukemia-Lymphoma/*drug therapy , Precursor Cell Lymphoblastic Leukemia-Lymphoma/*pathology , beta-Lactams/*pharmacology, Antineoplastic Agents/chemical synthesis ; Antineoplastic Agents/chemistry ; Azetines/chemical synthesis ; Azetines/chemistry ; Cell Proliferation/drug effects ; Child ; Child, Preschool ; Cytochromes c/antagonists & inhibitors ; Cytochromes c/metabolism ; Cytosol/drug effects ; Cytosol/metabolism ; Dose-Response Relationship, Drug ; Drug Screening Assays, Antitumor ; Female ; Humans ; Male ; Reactive Oxygen Species/antagonists & inhibitors ; Reactive Oxygen Species/metabolism ; Structure-Activity Relationship ; beta-Lactams/chemical synthesis ; beta-Lactams/chemistry

المؤلفون: Wearing ER; University of Michigan, Department of Chemistry, Willard Henry Dow Laboratory, 930 North University Ave., Ann Arbor, Michigan 48109, United States., Blackmun DE; University of Michigan, Department of Chemistry, Willard Henry Dow Laboratory, 930 North University Ave., Ann Arbor, Michigan 48109, United States., Becker MR; University of Michigan, Department of Chemistry, Willard Henry Dow Laboratory, 930 North University Ave., Ann Arbor, Michigan 48109, United States., Schindler CS; University of Michigan, Department of Chemistry, Willard Henry Dow Laboratory, 930 North University Ave., Ann Arbor, Michigan 48109, United States.

المصدر: Journal of the American Chemical Society [J Am Chem Soc] 2021 Oct 06; Vol. 143 (39), pp. 16235-16242. Date of Electronic Publication: 2021 Sep 27.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE

مواضيع طبية MeSH: Photochemical Processes*, Alkynes/*chemistry , Azetines/*chemical synthesis , Cycloaddition Reaction/*methods , Oximes/*chemistry, Light ; Molecular Structure

المؤلفون: Ruan Z; Center of Clinical Pharmacology, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China., Jiang B, Chen J, Zhang X, Lou H, Xiang M, Shao Q, Wang J

المصدر: Journal of clinical pharmacology [J Clin Pharmacol] 2014 Oct; Vol. 54 (10), pp. 1144-52. Date of Electronic Publication: 2014 Apr 21.

نوع المنشور: Clinical Trial, Phase I; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley Country of Publication: England NLM ID: 0366372 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4604 (Electronic) Linking ISSN: 00912700 NLM ISO Abbreviation: J Clin Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Anticholesteremic Agents/*administration & dosage , Azetines/*administration & dosage , Cholesterol, LDL/*blood , Fluorobenzenes/*administration & dosage, Adult ; Anticholesteremic Agents/pharmacokinetics ; Anticholesteremic Agents/pharmacology ; Area Under Curve ; Asian People ; Azetines/pharmacokinetics ; Azetines/pharmacology ; Cross-Over Studies ; Dose-Response Relationship, Drug ; Double-Blind Method ; Female ; Fluorobenzenes/pharmacokinetics ; Fluorobenzenes/pharmacology ; Food-Drug Interactions ; Half-Life ; Humans ; Male ; Young Adult

المؤلفون: Chen J; Center of Clinical Pharmacology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China., Lou H; Center of Clinical Pharmacology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China., Jiang B; Center of Clinical Pharmacology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China., Shao R; Center of Clinical Pharmacology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China., Ruan Z; Center of Clinical Pharmacology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China., Wang J; Center of Clinical Pharmacology, the Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.

المصدر: Bioanalysis [Bioanalysis] 2015; Vol. 7 (15), pp. 1857-67.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Future Science Country of Publication: England NLM ID: 101512484 Publication Model: Print Cited Medium: Internet ISSN: 1757-6199 (Electronic) Linking ISSN: 17576180 NLM ISO Abbreviation: Bioanalysis Subsets: MEDLINE

مواضيع طبية MeSH: Anticholesteremic Agents/*chemistry , Azetines/*chemistry , Chromatography, Liquid/*methods , Fluorobenzenes/*chemistry , Tandem Mass Spectrometry/*methods, Anticholesteremic Agents/metabolism ; Azetines/metabolism ; Fluorobenzenes/metabolism ; Humans

المؤلفون: Marichev KO; Department of Chemistry, The University of Texas at San Antonio, San Antonio, TX, 78249, USA., Dong K; Department of Chemistry, The University of Texas at San Antonio, San Antonio, TX, 78249, USA., Massey LA; Department of Chemistry, The University of Texas at San Antonio, San Antonio, TX, 78249, USA., Deng Y; Department of Chemistry, The University of Texas at San Antonio, San Antonio, TX, 78249, USA., De Angelis L; Department of Chemistry, The University of Texas at San Antonio, San Antonio, TX, 78249, USA., Wang K; Department of Chemistry, The University of Texas at San Antonio, San Antonio, TX, 78249, USA., Arman H; Department of Chemistry, The University of Texas at San Antonio, San Antonio, TX, 78249, USA., Doyle MP; Department of Chemistry, The University of Texas at San Antonio, San Antonio, TX, 78249, USA. michael.doyle@utsa.edu.

المصدر: Nature communications [Nat Commun] 2019 Nov 22; Vol. 10 (1), pp. 5328. Date of Electronic Publication: 2019 Nov 22.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Azetines/*chemical synthesis , Cycloaddition Reaction/*methods, Amino Acids ; Azetidines ; Catalysis ; Chemistry Techniques, Synthetic/methods ; Diazonium Compounds ; Indicators and Reagents/chemical synthesis ; Stereoisomerism