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المؤلفون: George H. Addona, David Jonathan Bennett, Brian J. Long, Sheila Ranganath, Anuradha Khilnani, Archie Tse, B. Wesley Trotter, Jared Cumming, Saso Cemerski, Ian Knemeyer, Vincenzo Pucci, Hyun Chong Woo, Sharad K. Sharma, Shuxia Zhao, Bo-Sheng Pan, Jennifer Piesvaux, Heidi M. Ferguson, Ellen C. Minnihan, Sarah Javaid, Manjiri Sathe, Jeremy Presland, Long Cui, Yiping Chen, Kalyan Chakravarthy, Jason Laskey, Eric S. Muise, Yanhong Ma, Johnny E. Kopinja, Samanthi A. Perera
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e6fcaf4831f75b8eb5c4beefa54ae209
https://doi.org/10.1158/1535-7163.22522690.v1 -
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المؤلفون: George H. Addona, David Jonathan Bennett, Brian J. Long, Sheila Ranganath, Anuradha Khilnani, Archie Tse, B. Wesley Trotter, Jared Cumming, Saso Cemerski, Ian Knemeyer, Vincenzo Pucci, Hyun Chong Woo, Sharad K. Sharma, Shuxia Zhao, Bo-Sheng Pan, Jennifer Piesvaux, Heidi M. Ferguson, Ellen C. Minnihan, Sarah Javaid, Manjiri Sathe, Jeremy Presland, Long Cui, Yiping Chen, Kalyan Chakravarthy, Jason Laskey, Eric S. Muise, Yanhong Ma, Johnny E. Kopinja, Samanthi A. Perera
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3debc597dc269548a67fe876b174413a
https://doi.org/10.1158/1535-7163.22522684 -
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المؤلفون: George H. Addona, David Jonathan Bennett, Brian J. Long, Sheila Ranganath, Anuradha Khilnani, Archie Tse, B. Wesley Trotter, Jared Cumming, Saso Cemerski, Ian Knemeyer, Vincenzo Pucci, Hyun Chong Woo, Sharad K. Sharma, Shuxia Zhao, Bo-Sheng Pan, Jennifer Piesvaux, Heidi M. Ferguson, Ellen C. Minnihan, Sarah Javaid, Manjiri Sathe, Jeremy Presland, Long Cui, Yiping Chen, Kalyan Chakravarthy, Jason Laskey, Eric S. Muise, Yanhong Ma, Johnny E. Kopinja, Samanthi A. Perera
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5490569e56c5aaab6a439f8f48897ab7
https://doi.org/10.1158/1535-7163.22522681.v1 -
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المؤلفون: Prasanthi Geda, Mark A. McCoy, Liping Yang, Chaomin Li, Armetta D. Hill, Xavier Fradera, Marianne L. Spatz, Matthew Ernst Voss, Carolyn Michele Cammarano, Pierre Daublain, Xiao Wang, Christopher F. Thompson, B. Wesley Trotter, C. Gary Marshall, Michael H. Reutershan, Peter Goldenblatt, Latha G. Nair, Manami Shizuka, Tammie C. Yeh, John G. Cryan, Isabelle Dussault, Michelle Martinez, Mingmei Cai, Raymond A. Kemper, Binyuan Sun, Michelle R. Machacek, Dietrich Steinhuebel, Giovanna Scapin, Michael D. Altman, Stephane L. Bogen, Matthew Christopher, Dapeng Chen, Victoria Kutilek, Weidong Pan
المصدر: Journal of Medicinal Chemistry. 64:16213-16241
مصطلحات موضوعية: Chemistry, Clinical investigation, Drug Discovery, P53 protein, Molecular Medicine, Computational biology
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المؤلفون: Wonsuk Chang, Michael D. Altman, Charles A. Lesburg, Samanthi A. Perera, Jennifer A. Piesvaux, Gottfried K. Schroeder, Daniel F. Wyss, Saso Cemerski, Yiping Chen, Edward DiNunzio, Andrew M. Haidle, Thu Ho, Ilona Kariv, Ian Knemeyer, Johnny E. Kopinja, Brian M. Lacey, Jason Laskey, Jongwon Lim, Brian J. Long, Yanhong Ma, Matthew L. Maddess, Bo-Sheng Pan, Jeremy P. Presland, Edward Spooner, Dietrich Steinhuebel, Quang Truong, Zhibo Zhang, Jianmin Fu, George H. Addona, Alan B. Northrup, Emma Parmee, James R. Tata, David Jonathan Bennett, Jared N. Cumming, Tony Siu, B. Wesley Trotter
المصدر: Journal of medicinal chemistry. 65(7)
مصطلحات موضوعية: Mice, Neoplasms, Drug Discovery, Molecular Medicine, Animals, Cytokines, Humans, Membrane Proteins, Immunotherapy, Interferons
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المؤلفون: Xavier Fradera, Michael H. Reutershan, Michelle R. Machacek, B. Wesley Trotter, Mark A. McCoy
المصدر: Chembiochem : a European journal of chemical biology. 23(6)
مصطلحات موضوعية: Models, Molecular, Binding Sites, Magnetic Resonance Spectroscopy, Protein Conformation, Organic Chemistry, Molecular Medicine, Proteins, Ligands, Molecular Biology, Biochemistry, Protein Binding
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المؤلفون: Matthew H. Daniels, Sunil Nagpal, Blair T. Lapointe, Jos Cals, Mario van der Stelt, Vladimir Simov, Willem Jan Karstens, Sujal V. Deshmukh, Kenneth Jay Barr, J. Richard Miller, Hans van Eenenaam, Craig C. Correll, John Maclean, Laxminarayan G Hegde, Lily Y. Moy, B. Wesley Trotter, Rachel L. Palte, Janice D Woodhouse, Nunzio Sciammetta, Gopal Parthasarathy, Heidi Ferguson, Rita Azevedo, Hongjun Zhang, Arthur Oubrie, Neville J. Anthony
المصدر: ACS Medicinal Chemistry Letters. 11:114-119
مصطلحات موضوعية: medicine.drug_class, Chemistry, Organic Chemistry, Allosteric regulation, Monoclonal antibody, Biochemistry, Combinatorial chemistry, Small molecule, chemistry.chemical_compound, Nuclear receptor, RAR-related orphan receptor gamma, Drug Discovery, medicine, Moiety, Piperidine, Benzoic acid
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المؤلفون: Michael H, Reutershan, Michelle R, Machacek, Michael D, Altman, Stephane, Bogen, Mingmei, Cai, Carolyn, Cammarano, Dapeng, Chen, Matthew, Christopher, John, Cryan, Pierre, Daublain, Xavier, Fradera, Prasanthi, Geda, Peter, Goldenblatt, Armetta D, Hill, Raymond A, Kemper, Victoria, Kutilek, Chaomin, Li, Michelle, Martinez, Mark, McCoy, Latha, Nair, Weidong, Pan, Christopher F, Thompson, Giovanna, Scapin, Manami, Shizuka, Marianne L, Spatz, Dietrich, Steinhuebel, Binyuan, Sun, Matthew E, Voss, Xiao, Wang, Liping, Yang, Tammie C, Yeh, Isabelle, Dussault, C Gary, Marshall, B Wesley, Trotter
المصدر: Journal of medicinal chemistry. 64(21)
مصطلحات موضوعية: Structure-Activity Relationship, Pyridines, Imidazoles, Humans, Proto-Oncogene Proteins c-mdm2, Tumor Suppressor Protein p53, Protein Binding
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المؤلفون: John A. McIntosh, Zhijian Liu, Brian M. Andresen, Nastaran Salehi Marzijarani, Jeffrey C. Moore, Nicholas M. Marshall, Margie Borra-Garske, Jennifer V. Obligacion, Patrick S. Fier, Feng Peng, Jacob H. Forstater, Matthew S. Winston, Chihui An, Wonsuk Chang, Jongwon Lim, Mark A. Huffman, Steven P. Miller, Fuh-Rong Tsay, Michael D. Altman, Charles A. Lesburg, Dietrich Steinhuebel, B. Wesley Trotter, Jared N. Cumming, Alan Northrup, Xiaodong Bu, Benjamin F. Mann, Mirlinda Biba, Kaori Hiraga, Grant S. Murphy, Joshua N. Kolev, Amanda Makarewicz, Weilan Pan, Iman Farasat, Rachel S. Bade, Kevin Stone, Da Duan, Oscar Alvizo, Donovan Adpressa, Erik Guetschow, Erik Hoyt, Erik L. Regalado, Steve Castro, Nelo Rivera, Joseph P. Smith, Fengqiang Wang, Alejandro Crespo, Deeptak Verma, Stephanus Axnanda, Zachary E. X. Dance, Paul N. Devine, David Tschaen, Keith A. Canada, Paul G. Bulger, Benjamin D. Sherry, Matthew D. Truppo, Rebecca T. Ruck, Louis-Charles Campeau, David Jonathan Bennett, Guy R. Humphrey, Kevin R. Campos, Matthew L. Maddess
المصدر: Nature. 603(7901)
مصطلحات موضوعية: Multidisciplinary, Adenosine, Guanosine, Animals, Membrane Proteins, Interferons, Nucleotidyltransferases, Signal Transduction
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المؤلفون: Saso Cemerski, Jennifer Piesvaux, Jason Laskey, Brian Long, B. Wesley Trotter, Jared N. Cumming, Shuxia Zhao, Eric S. Muise, Yanhong Ma, Ellen C. Minnihan, Samanthi A. Perera, Sheila Ranganath, Sarah Javaid, Bo-Sheng Pan, Sharad K. Sharma, Yiping Chen, Jeremy Presland, Long Cui, Manjiri Sathe, Archie Tse, Kalyan Chakravarthy, Vincenzo Pucci, Ian Knemeyer, Hyun Chong Woo, David Jonathan Bennett, Anuradha D. Khilnani, George H. Addona, Heidi Ferguson, Johnny E. Kopinja
المصدر: Molecular cancer therapeutics. 21(2)
مصطلحات موضوعية: Agonist, Cancer Research, Innate immune system, medicine.drug_class, Chemistry, medicine.medical_treatment, Type I interferon production, Immunity, Innate, Sting, Mice, Cytokine, Immune system, Oncology, Downregulation and upregulation, Stimulator of interferon genes, Cell Line, Tumor, Neoplasms, medicine, Cancer research, Animals, Humans, Female, Immunotherapy, Interferons
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdf6ca49160ce75bedb7022ed181f14a
https://pubmed.ncbi.nlm.nih.gov/34815361
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