المؤلفون: Dai H; Cardiovascular Center, The Affiliated Hospital of Yunnan University, Yunnan University, Kunming, Yunnan, China.; School of Medicine, Yunnan University, Kunming, Yunnan, China., Liu Y; Department of Gynecology, Yunnan Cancer Hospital and The Third Affiliated Hospital of Kunming Medical University, Kunming, Yunnan, China., Zhu M; Department of Geriatrics, The Affiliated Huaian Hospital of Xuzhou Medical University, Huaian Second People's Hospital, Huaian, Jiangsu, China., Tao S; Cardiovascular Center, The Affiliated Hospital of Yunnan University, Yunnan University, Kunming, Yunnan, China., Hu C; Cardiovascular Center, The Affiliated Hospital of Yunnan University, Yunnan University, Kunming, Yunnan, China., Luo P; Department of Oncology, Zhujiang Hospital, Southern Medical University, Guangzhou, China., Jiang A; Department of Urology, Changzheng Hospital, Naval Medical University, Shanghai, China., Zhang G; Cardiovascular Center, The Affiliated Hospital of Yunnan University, Yunnan University, Kunming, Yunnan, China.; School of Medicine, Yunnan University, Kunming, Yunnan, China.

المصدر: Journal of cellular and molecular medicine [J Cell Mol Med] 2024 Aug; Vol. 28 (16), pp. e70034.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101083777 Publication Model: Print Cited Medium: Internet ISSN: 1582-4934 (Electronic) Linking ISSN: 15821838 NLM ISO Abbreviation: J Cell Mol Med Subsets: MEDLINE

مواضيع طبية MeSH: Cardiomyopathy, Hypertrophic*/metabolism , Cardiomyopathy, Hypertrophic*/diagnosis , Cardiomyopathy, Hypertrophic*/genetics , Machine Learning* , Neoplasms*/metabolism , Neoplasms*/diagnosis , Neoplasms*/genetics , Neoplasms*/pathology , Biomarkers*/metabolism, Humans ; Male ; Female ; Prognosis ; Biomarkers, Tumor/metabolism ; Biomarkers, Tumor/genetics ; Middle Aged ; Nomograms

المؤلفون: Li Q; Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing 210003, China.; Department of Epidemiology and Health Statistics, School of Public Health, Southeast University, Nanjing 210003, China., Xu Z; Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing 210003, China.; Department of Epidemiology and Health Statistics, School of Public Health, Southeast University, Nanjing 210003, China., Gong Q; Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing 210003, China.; Department of Epidemiology and Health Statistics, School of Public Health, Southeast University, Nanjing 210003, China., Shen X; Key Laboratory of Environmental Medicine Engineering, Ministry of Education, School of Public Health, Southeast University, Nanjing 210003, China.; Department of Epidemiology and Health Statistics, School of Public Health, Southeast University, Nanjing 210003, China.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 21; Vol. 25 (16). Date of Electronic Publication: 2024 Aug 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Altitude Sickness*/genetics , Biomarkers, Tumor*/genetics , Biomarkers, Tumor*/metabolism , Glycoproteins*/genetics , Glycoproteins*/metabolism , Neoplasms*/genetics , Neoplasms*/metabolism, Humans ; Altitude ; Biomarkers ; Prognosis ; Tumor Microenvironment/genetics

المؤلفون: Pacifico F; Istituto per l'Endocrinologia e l'Oncologia Sperimentale, CNR, Via S. Pansini 5, 80131 Naples, Italy., Magni F; Proteomics and Metabolomics Unit, Department of Medicine and Surgery, University of Milano-Bicocca, 20854 Vedano al Lambro, Italy., Leonardi A; Dipartimento di Medicina Molecolare e Biotecnologie Mediche, University of Naples 'Federico II', Via S. Pansini 5, 80131 Naples, Italy., Crescenzi E; Istituto per l'Endocrinologia e l'Oncologia Sperimentale, CNR, Via S. Pansini 5, 80131 Naples, Italy.

المصدر: International journal of molecular sciences [Int J Mol Sci] 2024 Aug 02; Vol. 25 (15). Date of Electronic Publication: 2024 Aug 02.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101092791 Publication Model: Electronic Cited Medium: Internet ISSN: 1422-0067 (Electronic) Linking ISSN: 14220067 NLM ISO Abbreviation: Int J Mol Sci Subsets: MEDLINE

مواضيع طبية MeSH: Neoplasms*/metabolism , Neoplasms*/pathology , Cellular Senescence* , Biomarkers, Tumor*/metabolism , Tumor Microenvironment* , Senescence-Associated Secretory Phenotype*, Humans ; Animals ; Biomarkers ; Senotherapeutics/pharmacology

المؤلفون: Gong L; School of Pharmacy and Bioengineering, Chongqing University of Technology, Chongqing 400054, China., Wu S; School of Pharmacy and Bioengineering, Chongqing University of Technology, Chongqing 400054, China. Electronic address: sxwu2004@cqut.edu.cn., Liu J; School of Pharmacy and Bioengineering, Chongqing University of Technology, Chongqing 400054, China., Zhang M; Laboratory Department of Chongqing Jiulongpo District People's Hospital, Chongqing, 400050, China., Zhuang J; Department of Physics and Energy, Chongqing University of Technology, Chongqing 400054, China., Xu D; NMPA Key Laboratory for Quality Monitoring of Narcotic Drugs and Psychotropic Substances, Chongqing Institute for Food and Drug Control, Chongqing, 401121, China. Electronic address: xudoudou@cqifdc.org.cn.

المصدر: Talanta [Talanta] 2024 Aug 01; Vol. 275, pp. 126082. Date of Electronic Publication: 2024 Apr 16.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 2984816R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3573 (Electronic) Linking ISSN: 00399140 NLM ISO Abbreviation: Talanta Subsets: MEDLINE

مواضيع طبية MeSH: Titanium*/chemistry , Gold*/chemistry , Liver Neoplasms*/diagnosis , Biomarkers, Tumor*/analysis , Biomarkers, Tumor*/immunology , Prothrombin*/chemistry , Biosensing Techniques*/methods , Cysteine*/chemistry, Humans ; Immunoassay/methods ; Metal Nanoparticles/chemistry ; Limit of Detection ; Electrodes ; Carcinoma, Hepatocellular/diagnosis ; Protein Precursors ; Biomarkers

المؤلفون: Chen Y; Institute for Health Innovation & Technology, National University of Singapore, Singapore, Singapore.; Department of Biomedical Engineering, College of Design and Engineering, National University of Singapore, Singapore, Singapore., Zhang L; Institute for Health Innovation & Technology, National University of Singapore, Singapore, Singapore.; Department of Biomedical Engineering, College of Design and Engineering, National University of Singapore, Singapore, Singapore., Wu X; Institute for Health Innovation & Technology, National University of Singapore, Singapore, Singapore., Sun X; Institute for Health Innovation & Technology, National University of Singapore, Singapore, Singapore., Sundah NR; Institute for Health Innovation & Technology, National University of Singapore, Singapore, Singapore.; Department of Biomedical Engineering, College of Design and Engineering, National University of Singapore, Singapore, Singapore., Wong CY; Institute for Health Innovation & Technology, National University of Singapore, Singapore, Singapore.; Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Natalia A; Institute for Health Innovation & Technology, National University of Singapore, Singapore, Singapore.; Department of Biomedical Engineering, College of Design and Engineering, National University of Singapore, Singapore, Singapore., Tam JKC; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore., Lim DW; Division of Medical Oncology, National Cancer Centre Singapore, Singapore, Singapore.; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore, Singapore.; Centre for Clinician-Scientist Development, Duke-NUS Medical School, Singapore, Singapore., Chowbay B; Centre for Clinician-Scientist Development, Duke-NUS Medical School, Singapore, Singapore.; Clinical Pharmacology Laboratory, National Cancer Centre Singapore, Singapore, Singapore.; Singapore Immunology Network, Agency for Science, Technology and Research, Singapore, Singapore., Ang BT; National Neuroscience Institute, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore., Tang C; National Neuroscience Institute, Singapore, Singapore.; Duke-NUS Medical School, Singapore, Singapore.; SG Enable, Innovation, Singapore, Singapore., Loh TP; Institute for Health Innovation & Technology, National University of Singapore, Singapore, Singapore.; Department of Laboratory Medicine, National University Hospital, Singapore, Singapore., Shao H; Institute for Health Innovation & Technology, National University of Singapore, Singapore, Singapore. huilin.shao@nus.edu.sg.; Department of Biomedical Engineering, College of Design and Engineering, National University of Singapore, Singapore, Singapore. huilin.shao@nus.edu.sg.; Department of Surgery, Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore. huilin.shao@nus.edu.sg.; Institute of Molecular and Cell Biology, Agency for Science, Technology and Research, Singapore, Singapore. huilin.shao@nus.edu.sg.

المصدر: Nature communications [Nat Commun] 2024 Sep 27; Vol. 15 (1), pp. 8410. Date of Electronic Publication: 2024 Sep 27.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Biosensing Techniques*/methods , Biomarkers, Tumor*/blood, Humans ; Hydrogels/chemistry ; Magnetite Nanoparticles/chemistry ; Magnetics ; Biomarkers/blood ; RNA/blood ; Magnetic Fields ; Neoplasms/blood

المؤلفون: Saeki I; Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan., Shimose S; Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan., Tomonari T; Department of Gastroenterology and Oncology, Institute of Biomedical Sciences, Tokushima University Graduate School of Medicine, Tokushima, Japan., Ito T; Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan., Tani J; Department of Gastroenterology and Neurology, Kagawa University, Faculty of Medicine, Kagawa, Japan., Takeuchi Y; Department of Regenerative Medicine, Center for Innovative Clinical Medicine, Okayama University Hospital, Okayama, Japan., Yoshioka N; Department of Gastroenterology and Hepatology, Japanese Red Cross Aichi Medical Center Nagoya Daiichi Hospital, Nagoya, Aichi, Japan., Naito T; Department of Gastroenterology, Toyohashi Municipal Hospital, Toyohashi, Aichi, Japan., Takeuchi M; Department of Gastroenterology, Anjo Kosei Hospital, Anjo, Japan., Kakizaki S; Department of Clinical Research, NHO Takasaki General Medical Center, Takasaki, Gunma, Japan., Hatanaka T; Department of Gastroenterology, Gunma Saiseikai Maebashi Hospital, Maebashi, Japan., Sasaki K; Department of Gastroenterology and Hepatology, Kawasaki Medical School, Kurashiki, Japan., Yasunaka T; Department of Gastroenterology, Fukuyama City Hospital, Okayama, Japan., Sakata M; Department of Gastroenterology, NHO Fukuyama Medical Center, Fukuyama, Japan., Iwamoto H; Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan.; Iwamoto Internal Medical Clinic, Kitakyusyu, Japan., Itano S; Department of Gastroenterology and Hepatology, Kurume Central Hospital, Kurume, Japan., Shirono T; Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan., Tanabe N; Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan.; Division of Laboratory, Yamaguchi University Hospital, Yamaguchi, Japan., Yamamoto T; Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan., Kanayama Y; Department of Gastroenterology, Gunma Saiseikai Maebashi Hospital, Maebashi, Japan., Naganuma A; Department of Gastroenterology, NHO Takasaki General Medical Center, Takasaki, Gunma, Japan., Nishina S; Department of Gastroenterology and Hepatology, Kawasaki Medical School, Kurashiki, Japan., Otsuka M; Department of Gastroenterology and Hepatology, Okayama University Hospital, Okayama, Japan., Kobara H; Department of Gastroenterology and Neurology, Kagawa University, Faculty of Medicine, Kagawa, Japan., Kawashima H; Department of Gastroenterology and Hepatology, Nagoya University Graduate School of Medicine, Nagoya, Aichi, Japan., Takayama T; Department of Gastroenterology and Oncology, Institute of Biomedical Sciences, Tokushima University Graduate School of Medicine, Tokushima, Japan., Kawaguchi T; Division of Gastroenterology, Department of Medicine, Kurume University School of Medicine, Kurume, Japan., Yamasaki T; Department of Oncology and Laboratory Medicine, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan., Takami T; Department of Gastroenterology and Hepatology, Yamaguchi University Graduate School of Medicine, Yamaguchi, Japan.

مؤلفون مشاركون: Hepatology InVestigator Experts in Japan (HIVE-J) Study Group

المصدر: PloS one [PLoS One] 2024 Sep 25; Vol. 19 (9), pp. e0311084. Date of Electronic Publication: 2024 Sep 25 (Print Publication: 2024).

نوع المنشور: Journal Article; Multicenter Study

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Hepatocellular*/drug therapy , Carcinoma, Hepatocellular*/blood , Carcinoma, Hepatocellular*/pathology , alpha-Fetoproteins*/metabolism , alpha-Fetoproteins*/analysis , Prothrombin*/metabolism , Liver Neoplasms*/drug therapy , Liver Neoplasms*/blood , Liver Neoplasms*/pathology , Antibodies, Monoclonal, Humanized*/therapeutic use , Antibodies, Monoclonal*/therapeutic use , Antibodies, Monoclonal*/administration & dosage , Protein Precursors* , Biomarkers, Tumor*/blood, Humans ; Male ; Female ; Middle Aged ; Aged ; Retrospective Studies ; Antineoplastic Combined Chemotherapy Protocols/therapeutic use ; Adult ; Prognosis ; Treatment Outcome ; Biomarkers

المؤلفون: Elkahwagy DMAS; Pharmaceutical Biology Department, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo, 11835, Egypt. dina.ahmed-samir@guc.edu.eg., Kiriacos CJ; Pharmaceutical Biology Department, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo, 11835, Egypt., Mansour M; Pharmaceutical Biology Department, Faculty of Pharmacy and Biotechnology, German University in Cairo, Cairo, 11835, Egypt.

المصدر: Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico [Clin Transl Oncol] 2024 Sep; Vol. 26 (9), pp. 2172-2180. Date of Electronic Publication: 2024 Mar 26.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Country of Publication: Italy NLM ID: 101247119 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1699-3055 (Electronic) Linking ISSN: 1699048X NLM ISO Abbreviation: Clin Transl Oncol Subsets: MEDLINE

مواضيع طبية MeSH: Biomarkers, Tumor*/analysis, Humans ; Logistic Models ; Biomarkers/analysis ; Neoplasms/diagnosis

المؤلفون: Tong B; Department of Clinical Laboratory, Jinhua Municipal Central Hospital, Jinhua Hospital of Zhejiang University, Jinhua, China., Cheng W; Department of Clinical Laboratory, Linping Hospital of Integrated Traditional Chinese and Western Medicine, Hangzhou, Zhejiang, China. 157480943@qq.com.

المصدر: Clinical rheumatology [Clin Rheumatol] 2024 Sep; Vol. 43 (9), pp. 3037-3038. Date of Electronic Publication: 2024 Jul 22.

نوع المنشور: Letter

بيانات الدورية: Publisher: Springer Country of Publication: Germany NLM ID: 8211469 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1434-9949 (Electronic) Linking ISSN: 07703198 NLM ISO Abbreviation: Clin Rheumatol Subsets: MEDLINE

مواضيع طبية MeSH: Arthritis, Rheumatoid*/complications , Lung Diseases, Interstitial*/complications , Lung Diseases, Interstitial*/etiology , Lung Diseases, Interstitial*/diagnosis , Biomarkers*/blood, Humans ; Biomarkers, Tumor/blood ; Inflammation

المؤلفون: Zertuche-Martínez C; Laboratorio de Fibrosis y cáncer, Facultad de Medicina y Cirugía, Universidad Autónoma Benito Juárez de Oaxaca, Oaxaca de Juárez 68120, Oaxaca, Mexico., Velázquez-Enríquez JM; Laboratorio de Fibrosis y cáncer, Facultad de Medicina y Cirugía, Universidad Autónoma Benito Juárez de Oaxaca, Oaxaca de Juárez 68120, Oaxaca, Mexico., González-García K; Laboratorio de Fibrosis y cáncer, Facultad de Medicina y Cirugía, Universidad Autónoma Benito Juárez de Oaxaca, Oaxaca de Juárez 68120, Oaxaca, Mexico., Santos-Álvarez JC; Laboratorio de Fibrosis y cáncer, Facultad de Medicina y Cirugía, Universidad Autónoma Benito Juárez de Oaxaca, Oaxaca de Juárez 68120, Oaxaca, Mexico., Romero-Tlalolini MLÁ; CONAHCYT-Facultad de Medicina y Cirugía, Universidad Autónoma Benito Juárez de Oaxaca, Oaxaca de Juárez 68120, Oaxaca, Mexico. vrvasquezga@conacyt.mx., Pina-Canseco S; Centro de Investigación Facultad de Medicina UNAM UABJO, Facultad de Medicina y Cirugía, Universidad Autónoma Benito Juárez de Oaxaca, Oaxaca de Juárez 68120, Oaxaca, Mexico., Pérez-Campos Mayoral L; Centro de Investigación Facultad de Medicina UNAM UABJO, Facultad de Medicina y Cirugía, Universidad Autónoma Benito Juárez de Oaxaca, Oaxaca de Juárez 68120, Oaxaca, Mexico., Muriel P; Laboratorio de Hepatología Experimental, Departamento de Farmacología, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV-IPN), Ciudad de México 07000, Mexico., Villa-Treviño S; Departamento de Biología Celular, Centro de Investigación y de Estudios Avanzados del Instituto Politécnico Nacional (CINVESTAV-IPN), Ciudad de México 07360, Mexico., Baltiérrez-Hoyos R; CONAHCYT-Facultad de Medicina y Cirugía, Universidad Autónoma Benito Juárez de Oaxaca, Oaxaca de Juárez 68120, Oaxaca, Mexico. vrvasquezga@conacyt.mx., Arellanes-Robledo J; CONAHCYT-Instituto Nacional de Medicina Genómica, Ciudad de México 14610, Mexico., Vásquez-Garzón VR; CONAHCYT-Facultad de Medicina y Cirugía, Universidad Autónoma Benito Juárez de Oaxaca, Oaxaca de Juárez 68120, Oaxaca, Mexico. vrvasquezga@conacyt.mx.

المصدر: Molecular omics [Mol Omics] 2024 Aug 12; Vol. 20 (7), pp. 483-495. Date of Electronic Publication: 2024 Aug 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101713384 Publication Model: Electronic Cited Medium: Internet ISSN: 2515-4184 (Electronic) Linking ISSN: 25154184 NLM ISO Abbreviation: Mol Omics Subsets: MEDLINE

مواضيع طبية MeSH: Carcinoma, Hepatocellular*/blood , Carcinoma, Hepatocellular*/metabolism , Liver Neoplasms*/blood , Liver Neoplasms*/metabolism , Extracellular Vesicles*/metabolism , Liver Cirrhosis*/blood , Liver Cirrhosis*/metabolism , Proteomics*/methods , Biomarkers, Tumor*/blood, Humans ; Male ; Female ; Middle Aged ; Tandem Mass Spectrometry ; Proteome/metabolism ; Chromatography, Liquid ; Biomarkers/blood

المؤلفون: Li H; Department of Radiology, Huaxi MR Research Center (HMRRC), Frontiers Science Center for Disease-Related Molecular Network, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, No. 37 Guoxue Alley, Chengdu 610041, China., Gong Q; Department of Radiology, Huaxi MR Research Center (HMRRC), Frontiers Science Center for Disease-Related Molecular Network, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, No. 37 Guoxue Alley, Chengdu 610041, China.; Functional and Molecular Imaging Key Laboratory of Sichuan Province and Research Unit of Psychoradiology, Chinese Academy of Medical Sciences, Chengdu 610041, China.; Department of Radiology, West China Xiamen Hospital of Sichuan University, 699 Jinyuan Xi Road, Jimei District, 361021 Xiamen, Fujian, China., Luo K; Department of Radiology, Huaxi MR Research Center (HMRRC), Frontiers Science Center for Disease-Related Molecular Network, State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, No. 37 Guoxue Alley, Chengdu 610041, China.; Functional and Molecular Imaging Key Laboratory of Sichuan Province and Research Unit of Psychoradiology, Chinese Academy of Medical Sciences, Chengdu 610041, China.

المصدر: Theranostics [Theranostics] 2024 Jul 02; Vol. 14 (10), pp. 4127-4146. Date of Electronic Publication: 2024 Jul 02 (Print Publication: 2024).

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Ivyspring International Publisher Country of Publication: Australia NLM ID: 101552395 Publication Model: eCollection Cited Medium: Internet ISSN: 1838-7640 (Electronic) Linking ISSN: 18387640 NLM ISO Abbreviation: Theranostics Subsets: MEDLINE

مواضيع طبية MeSH: Neoplasms*/radiotherapy , Neoplasms*/diagnostic imaging , Molecular Imaging*/methods , Biomarkers, Tumor*/metabolism, Humans ; Animals ; Molecular Probes/chemistry ; Radiotherapy/methods ; Radiotherapy/adverse effects ; Biomarkers/metabolism