المؤلفون: He Y; School of Parmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China., Guo J; School of Parmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China; Innovation Research Institute of Traditional Chinese Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China., Ding H; School of Parmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China., Lin M; School of Parmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China., Wu Y; School of Parmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China., He Z; School of Parmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, China., Wang Z; School of Parmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China., Xia Q; School of Parmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China., Zhu C; School of Parmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China., Zhang Y; School of Parmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. Electronic address: analysisdrug@126.com., Feng N; School of Parmacy, Shanghai University of Traditional Chinese Medicine, Shanghai 201203, China. Electronic address: npfeng@shutcm.edu.cn.

المصدر: International journal of pharmaceutics [Int J Pharm] 2024 Jul 20; Vol. 660, pp. 124310. Date of Electronic Publication: 2024 Jun 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier/North-Holland Biomedical Press Country of Publication: Netherlands NLM ID: 7804127 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3476 (Electronic) Linking ISSN: 03785173 NLM ISO Abbreviation: Int J Pharm Subsets: MEDLINE

مواضيع طبية MeSH: Indocyanine Green*/administration & dosage , Indocyanine Green*/chemistry , Breast Neoplasms*/drug therapy , Breast Neoplasms*/pathology , Photochemotherapy*/methods , Biphenyl Compounds*/administration & dosage , Biphenyl Compounds*/chemistry , Metal-Organic Frameworks*/chemistry , Glutathione*/metabolism , Lignans*/administration & dosage , Lignans*/chemistry , Lignans*/pharmacology , Drug Liberation*, Animals ; Female ; Humans ; MCF-7 Cells ; Mice, Inbred BALB C ; Cyclodextrins/chemistry ; Mice ; Apoptosis/drug effects ; Nanoparticles/chemistry ; Nanoparticles/administration & dosage ; Drug Delivery Systems/methods ; Reactive Oxygen Species/metabolism ; Mice, Nude ; Drug Carriers/chemistry ; Allyl Compounds ; Phenols

المؤلفون: Sun H; Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China., Liu Y; Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China., Wang X; Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China., Shu L; Affiliated Hospital of Integrated Traditional Chinese and Western Medicine, Nanjing University of Chinese Medicine, Nanjing, China; State Key Laboratory of Oral Drug Delivery Systems of Chinese Materia Medica, Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China. Electronic address: shuluan2006@hotmail.com.

المصدر: European journal of pharmacology [Eur J Pharmacol] 2024 Jul 15; Vol. 975, pp. 176642. Date of Electronic Publication: 2024 May 14.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Lignans*/pharmacology , Lignans*/therapeutic use , Biphenyl Compounds*/pharmacology , Biphenyl Compounds*/therapeutic use , Depression*/drug therapy , Diabetes Mellitus, Experimental*/drug therapy , Diabetes Mellitus, Experimental*/complications , Network Pharmacology* , Receptors, Calcitriol*/metabolism , Receptors, Calcitriol*/agonists , Molecular Docking Simulation*, Animals ; Mice ; Male ; Antidepressive Agents/pharmacology ; Antidepressive Agents/therapeutic use ; Mice, Inbred C57BL ; Diet, High-Fat/adverse effects ; Retinoid X Receptor alpha/metabolism ; Hippocampus/drug effects ; Hippocampus/metabolism ; Autophagy/drug effects ; Behavior, Animal/drug effects ; Comorbidity ; Allyl Compounds ; Phenols

المؤلفون: Kim JH; Clinical Trials Center, Chungnam National University Hospital, 266 Munhwa-ro, Jung-gu, Daejeon, Republic of Korea.; Department of Medical Science, Chungnam National University College of Medicine, Daejeon, Republic of Korea., Song JH; Clinical Trials Center, Chungnam National University Hospital, 266 Munhwa-ro, Jung-gu, Daejeon, Republic of Korea.; Department of Medical Science, Chungnam National University College of Medicine, Daejeon, Republic of Korea., Kim M; Pharmaceutical Research and Technology Development Center, Chong Kun Dang Pharmaceutical Corporation, Yongin, Gyeonggi, Republic of Korea., Hong JH; Clinical Trials Center, Chungnam National University Hospital, 266 Munhwa-ro, Jung-gu, Daejeon, Republic of Korea.; Department of Pharmacology, Chungnam National University College of Medicine, Daejeon, Republic of Korea., Sunwoo J; Clinical Trials Center, Chungnam National University Hospital, 266 Munhwa-ro, Jung-gu, Daejeon, Republic of Korea. swj4991@cnuh.co.kr., Jung JG; Department of Family Medicine, Chungnam National University Hospital, Daejeon, Republic of Korea. jjg72@hanmail.net.; Department of Family Medicine, Chungnam National University College of Medicine, 266 Munhwa-ro, Jung-gu, Daejeon, Republic of Korea. jjg72@hanmail.net.

المصدر: Advances in therapy [Adv Ther] 2024 Jul; Vol. 41 (7), pp. 2808-2825. Date of Electronic Publication: 2024 May 21.

نوع المنشور: Journal Article; Randomized Controlled Trial; Comparative Study

بيانات الدورية: Publisher: Health Communications Inc Country of Publication: United States NLM ID: 8611864 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1865-8652 (Electronic) Linking ISSN: 0741238X NLM ISO Abbreviation: Adv Ther Subsets: MEDLINE

مواضيع طبية MeSH: Biphenyl Compounds*/pharmacokinetics , Biphenyl Compounds*/administration & dosage , Amlodipine*/pharmacokinetics , Amlodipine*/administration & dosage , Benzimidazoles*/pharmacokinetics , Benzimidazoles*/administration & dosage , Tetrazoles*/pharmacokinetics , Tetrazoles*/administration & dosage , Cross-Over Studies* , Drug Combinations* , Atorvastatin*/pharmacokinetics , Atorvastatin*/administration & dosage, Humans ; Male ; Adult ; Female ; Young Adult ; Area Under Curve ; Middle Aged ; Angiotensin II Type 1 Receptor Blockers/pharmacokinetics ; Angiotensin II Type 1 Receptor Blockers/administration & dosage ; Calcium Channel Blockers/pharmacokinetics ; Calcium Channel Blockers/administration & dosage ; Therapeutic Equivalency ; Antihypertensive Agents/pharmacokinetics ; Antihypertensive Agents/administration & dosage ; Heptanoic Acids/pharmacokinetics ; Heptanoic Acids/administration & dosage ; Healthy Volunteers

المؤلفون: Zhang W; School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, PR China., Fan Y; School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, PR China., Zhang Y; School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, PR China; State Key Laboratory of Neurology and Oncology Drug Development, Jiangsu Simcere Pharmaceutical Co., Ltd, 699-18 Xuan Wu Avenue, Nanjing 210042, PR China; Jiangsu Simcere Pharmaceutical Co, Ltd, 699-18 Xuan Wu Avenue, Nanjing 210042, PR China., Feng Y; School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, PR China., Luo Y; School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, PR China., Zhou X; School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, PR China., Chen Z; School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, PR China., Wang C; School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, PR China., Lu T; School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, PR China; State Key Laboratory of Natural Medicines, China Pharmaceutical University, 24 Tongjiaxiang, Nanjing 210009, PR China., Tang F; State Key Laboratory of Neurology and Oncology Drug Development, Jiangsu Simcere Pharmaceutical Co., Ltd, 699-18 Xuan Wu Avenue, Nanjing 210042, PR China; Jiangsu Simcere Pharmaceutical Co, Ltd, 699-18 Xuan Wu Avenue, Nanjing 210042, PR China. Electronic address: feng.tang@cn.simcere.com., Chen Y; School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, PR China. Electronic address: ydchen@cpu.edu.cn., Li H; School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, PR China. Electronic address: liashry@163.com., Jiao Y; School of Science, China Pharmaceutical University, 639 Longmian Avenue, Nanjing 211198, PR China. Electronic address: jiaoyu@cpu.edu.cn.

المصدر: Bioorganic chemistry [Bioorg Chem] 2024 Jul; Vol. 148, pp. 107433. Date of Electronic Publication: 2024 May 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

مواضيع طبية MeSH: Benzamides*/pharmacology , Benzamides*/chemistry , Benzamides*/chemical synthesis , Nitriles*/chemistry , Nitriles*/pharmacology , Phenylthiohydantoin*/pharmacology , Phenylthiohydantoin*/analogs & derivatives , Phenylthiohydantoin*/chemistry , Biphenyl Compounds*/pharmacology , Biphenyl Compounds*/antagonists & inhibitors , Receptors, Androgen*/metabolism , Antineoplastic Agents*/pharmacology , Antineoplastic Agents*/chemistry , Antineoplastic Agents*/chemical synthesis , Cell Proliferation*/drug effects , Prostatic Neoplasms*/drug therapy , Prostatic Neoplasms*/pathology , Prostatic Neoplasms*/metabolism , Drug Resistance, Neoplasm*/drug effects , Androgen Receptor Antagonists*/pharmacology , Androgen Receptor Antagonists*/chemistry , Androgen Receptor Antagonists*/chemical synthesis , Androgen Receptor Antagonists*/therapeutic use, Humans ; Male ; Structure-Activity Relationship ; Molecular Structure ; Drug Discovery ; Drug Screening Assays, Antitumor ; Dose-Response Relationship, Drug ; Cell Line, Tumor

المؤلفون: Pan X; Department of Emergency, Suichang People's Hospital, Lishui , PR China., Hua Z; Department of Nephrology, Suichang People's Hospital, Lishui, PR China., Fan G; Department of Breast Surgery, Suichang People's Hospital, Lishui, PR China., Feng Q; Intensive Care Unit, Quzhou Kecheng People's Hospital, Quzhou, PR China. qinglongfengicu@sina.com.

المصدر: Histology and histopathology [Histol Histopathol] 2024 Jul; Vol. 39 (7), pp. 921-934. Date of Electronic Publication: 2023 Dec 12.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Histology and Histopathology Country of Publication: Spain NLM ID: 8609357 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1699-5848 (Electronic) Linking ISSN: 02133911 NLM ISO Abbreviation: Histol Histopathol Subsets: MEDLINE

مواضيع طبية MeSH: Sirtuin 1*/metabolism , NLR Family, Pyrin Domain-Containing 3 Protein*/metabolism , Autophagy*/drug effects , Peritonitis*/immunology , Peritonitis*/drug therapy , Inflammasomes*/metabolism , Lignans*/pharmacology , Lignans*/therapeutic use , Disease Models, Animal* , Biphenyl Compounds*/pharmacology , Biphenyl Compounds*/therapeutic use , Rats, Sprague-Dawley*, Animals ; Mice ; Rats ; RAW 264.7 Cells ; Male ; Acute Disease ; Inflammation ; Signal Transduction/drug effects ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/therapeutic use ; Allyl Compounds ; Phenols

المؤلفون: Dai SY; Department of Medicinal Chemistry and Natural Medicine Chemistry, College of Pharmacy, Harbin Medical University, Harbin, 150081, PR China., Qin WX; Department of Medicinal Chemistry and Natural Medicine Chemistry, College of Pharmacy, Harbin Medical University, Harbin, 150081, PR China., Yu S; Department of Medicinal Chemistry and Natural Medicine Chemistry, College of Pharmacy, Harbin Medical University, Harbin, 150081, PR China., Li C; Department of Medicinal Chemistry and Natural Medicine Chemistry, College of Pharmacy, Harbin Medical University, Harbin, 150081, PR China., Yang YH; Department of Medicinal Chemistry and Natural Medicine Chemistry, College of Pharmacy, Harbin Medical University, Harbin, 150081, PR China. Electronic address: yangyihui19790508@sina.com., Pei YH; Department of Medicinal Chemistry and Natural Medicine Chemistry, College of Pharmacy, Harbin Medical University, Harbin, 150081, PR China. Electronic address: peiyueh@vip163.com.

المصدر: Phytochemistry [Phytochemistry] 2024 Jul; Vol. 223, pp. 114132. Date of Electronic Publication: 2024 May 05.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 0151434 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-3700 (Electronic) Linking ISSN: 00319422 NLM ISO Abbreviation: Phytochemistry Subsets: MEDLINE

مواضيع طبية MeSH: Lignans*/chemistry , Lignans*/pharmacology , Biphenyl Compounds*/antagonists & inhibitors , Biphenyl Compounds*/pharmacology , Biphenyl Compounds*/chemistry, Structure-Activity Relationship ; Humans ; Molecular Structure ; Allyl Compounds ; Phenols

المؤلفون: Ali ISM; Pharmaceutics Department, College of Pharmacy, University of Basrah, Basrah, Iraq., Sajad UA; Pharmaceutics Department, College of Pharmacy, University of Basrah, Basrah, Iraq.; Pharmaceutics Department, College of Pharmacy, Almaaqal University, Basrah, Iraq., Abdul Rasool BK; Department of Pharmaceutical Sciences, Dubai Pharmacy College for Girls, Dubai, United Arab Emirates.

المصدر: PloS one [PLoS One] 2024 Jun 06; Vol. 19 (6), pp. e0303900. Date of Electronic Publication: 2024 Jun 06 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE

مواضيع طبية MeSH: Benzimidazoles*/chemistry , Benzimidazoles*/pharmacokinetics , Tetrazoles*/chemistry , Tetrazoles*/pharmacokinetics , Solubility* , Biphenyl Compounds*/chemistry , Biphenyl Compounds*/pharmacokinetics , Polymers*/chemistry , Polymers*/pharmacokinetics, Povidone/chemistry ; Water/chemistry ; Hydrogen-Ion Concentration ; Biological Availability ; Drug Stability ; Drug Liberation ; Acrylates

المؤلفون: Li X; Department of Pharmacy, Personalized Drug Therapy Key Laboratory of Sichuan Province, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, 610072, China., Yuan Z; School of Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China., Wang Y; Geriatric Intensive Care Unit, Sichuan Geriatric Medical Center, Sichuan Provincial People's Hospital, University of Electronic Science and Technology of China, Chengdu, 610072, Sichuan Province, China., Wang W; Department of Biotherapy, Cancer Center and State Key Laboratory of Biotherapy, West China Hospital, Sichuan University, Chengdu, 610041, China; West China Medical Publishers, West China Hospital, Sichuan University, Chengdu, 610041, China. Electronic address: wangwenjing@wchscu.cn., Shi J; Department of Pharmacy, Personalized Drug Therapy Key Laboratory of Sichuan Province, Sichuan Academy of Medical Sciences & Sichuan Provincial People's Hospital, School of Medicine, University of Electronic Science and Technology of China, Chengdu, 610072, China. Electronic address: shijianyoude@126.com.

المصدر: European journal of medicinal chemistry [Eur J Med Chem] 2024 Jun 05; Vol. 272, pp. 116471. Date of Electronic Publication: 2024 Apr 30.

نوع المنشور: Journal Article; Review

بيانات الدورية: Publisher: Editions Scientifiques Elsevier Country of Publication: France NLM ID: 0420510 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1768-3254 (Electronic) Linking ISSN: 02235234 NLM ISO Abbreviation: Eur J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Lignans*/pharmacology , Lignans*/chemistry , Lignans*/chemical synthesis , Biphenyl Compounds*/pharmacology , Biphenyl Compounds*/antagonists & inhibitors , Biphenyl Compounds*/chemistry, Humans ; Structure-Activity Relationship ; Animals ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/chemical synthesis ; Neuroprotective Agents/pharmacology ; Neuroprotective Agents/chemistry ; Neuroprotective Agents/chemical synthesis ; Molecular Structure ; Anti-Inflammatory Agents/pharmacology ; Anti-Inflammatory Agents/chemistry ; Anti-Inflammatory Agents/chemical synthesis ; Anti-Infective Agents/pharmacology ; Anti-Infective Agents/chemistry ; Anti-Infective Agents/chemical synthesis ; Allyl Compounds ; Phenols

المؤلفون: Yang R; Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, School of Pharmaceutical Science, Hengyang Medical School, University of South China, Hengyang 421001, Hunan Province, China; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, Henan Province, China., Fu X; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, Henan Province, China., Fan J; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, Henan Province, China., Wang T; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, Henan Province, China., Song J; Department of Pharmacology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou 450001, China., Xu T; Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, School of Pharmaceutical Science, Hengyang Medical School, University of South China, Hengyang 421001, Hunan Province, China., Guo Y; Hunan Province Cooperative Innovation Center for Molecular Target New Drug Study, School of Pharmaceutical Science, Hengyang Medical School, University of South China, Hengyang 421001, Hunan Province, China; School of Pharmaceutical Sciences, Zhengzhou University, Zhengzhou 450001, Henan Province, China. Electronic address: guoyong_122@163.com., Zhang SY; Department of Pharmacology, School of Basic Medical Sciences, Zhengzhou University, Zhengzhou 450001, China. Electronic address: saiyangz@zzu.edu.cn.

المصدر: Bioorganic & medicinal chemistry [Bioorg Med Chem] 2024 Jun 01; Vol. 107, pp. 117762. Date of Electronic Publication: 2024 May 15.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: England NLM ID: 9413298 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1464-3391 (Electronic) Linking ISSN: 09680896 NLM ISO Abbreviation: Bioorg Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Lignans*/pharmacology , Lignans*/chemistry , Lignans*/chemical synthesis , Biphenyl Compounds*/pharmacology , Biphenyl Compounds*/antagonists & inhibitors , Biphenyl Compounds*/chemistry , Cell Proliferation*/drug effects , Drug Screening Assays, Antitumor* , YAP-Signaling Proteins*/metabolism, Humans ; Structure-Activity Relationship ; HCT116 Cells ; Molecular Structure ; Colonic Neoplasms/drug therapy ; Colonic Neoplasms/pathology ; Colonic Neoplasms/metabolism ; Sulfides/chemistry ; Sulfides/pharmacology ; Sulfides/chemical synthesis ; Transcription Factors/metabolism ; Transcription Factors/antagonists & inhibitors ; Antineoplastic Agents, Phytogenic/pharmacology ; Antineoplastic Agents, Phytogenic/chemistry ; Antineoplastic Agents, Phytogenic/chemical synthesis ; Dose-Response Relationship, Drug ; Antineoplastic Agents/pharmacology ; Antineoplastic Agents/chemistry ; Antineoplastic Agents/chemical synthesis ; Allyl Compounds ; Phenols

المؤلفون: Wang JS; School of Pharmaceutical Sciences, Institute of Drug Discovery and Development, Zhengzhou University, Zhengzhou 450001, China; Engineering Center of Catalysis and Synthesis for Chiral Molecules, Department of Chemistry, Fudan University, Shanghai 200433, China; Shanghai Engineering Center of Industrial Asymmetric Catalysis for Chiral Drugs, Shanghai 200433, China., Zhao KX; School of Pharmaceutical Sciences, Institute of Drug Discovery and Development, Zhengzhou University, Zhengzhou 450001, China; Engineering Center of Catalysis and Synthesis for Chiral Molecules, Department of Chemistry, Fudan University, Shanghai 200433, China; Shanghai Engineering Center of Industrial Asymmetric Catalysis for Chiral Drugs, Shanghai 200433, China., Zhang K; School of Pharmaceutical Sciences, Institute of Drug Discovery and Development, Zhengzhou University, Zhengzhou 450001, China; Engineering Center of Catalysis and Synthesis for Chiral Molecules, Department of Chemistry, Fudan University, Shanghai 200433, China; Shanghai Engineering Center of Industrial Asymmetric Catalysis for Chiral Drugs, Shanghai 200433, China., Pannecouque C; Rega Institute for Medical Research, KU Leuven, Herestraat 49 B-3000, Leuven, Belgium., De Clercq E; Rega Institute for Medical Research, KU Leuven, Herestraat 49 B-3000, Leuven, Belgium., Wang S; Engineering Center of Catalysis and Synthesis for Chiral Molecules, Department of Chemistry, Fudan University, Shanghai 200433, China; Shanghai Engineering Center of Industrial Asymmetric Catalysis for Chiral Drugs, Shanghai 200433, China. Electronic address: shuaiwang@fudan.edu.cn., Chen FE; School of Pharmaceutical Sciences, Institute of Drug Discovery and Development, Zhengzhou University, Zhengzhou 450001, China; Engineering Center of Catalysis and Synthesis for Chiral Molecules, Department of Chemistry, Fudan University, Shanghai 200433, China; Shanghai Engineering Center of Industrial Asymmetric Catalysis for Chiral Drugs, Shanghai 200433, China. Electronic address: rfchen@fudan.edu.cn.

المصدر: Bioorganic chemistry [Bioorg Chem] 2024 Jun; Vol. 147, pp. 107340. Date of Electronic Publication: 2024 Apr 05.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 1303703 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1090-2120 (Electronic) Linking ISSN: 00452068 NLM ISO Abbreviation: Bioorg Chem Subsets: MEDLINE

مواضيع طبية MeSH: Anti-HIV Agents*/pharmacology , Anti-HIV Agents*/chemistry , Anti-HIV Agents*/chemical synthesis , Biphenyl Compounds*/antagonists & inhibitors , Biphenyl Compounds*/pharmacology , Biphenyl Compounds*/chemistry , Drug Design* , HIV Reverse Transcriptase*/antagonists & inhibitors , HIV Reverse Transcriptase*/metabolism , HIV-1*/drug effects , HIV-1*/enzymology , Quinazolines*/pharmacology , Quinazolines*/chemistry , Quinazolines*/chemical synthesis , Reverse Transcriptase Inhibitors*/pharmacology , Reverse Transcriptase Inhibitors*/chemistry , Reverse Transcriptase Inhibitors*/chemical synthesis , Solubility*, Humans ; Dose-Response Relationship, Drug ; Drug Resistance, Viral/drug effects ; Microbial Sensitivity Tests ; Molecular Docking Simulation ; Molecular Structure ; Structure-Activity Relationship