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1
المؤلفون: Mingjiang Li, Shanfa Ren, Dongmei Li, Ming Wang, Xiaohe Li, Liang Zhang, Ting Xiao, Hao Ruan, Ronghao Sun, Dandi Gao, Honggang Zhou, Cheng Yang, Jianping Lin, Jiali Bao, Yuli Wei, Mengqi Cui
المصدر: Phytomedicine
مصطلحات موضوعية: dihydromyricetin, SARS-CoV-2 Mpro, Flavonols, Pharmaceutical Science, SMAD, Pharmacology, medicine.disease_cause, pulmonary inflammation, Virus Replication, TNF-α, tumor necrosis factor-α, Mice, Cydn, dynamic compliance, Mlg, mouse lung fibroblasts, Fibrosis, Drug Discovery, Pulmonary fibrosis, Ri, inspiratory resistance, IL-6, interleukin-6, Lung, Coronavirus 3C Proteases, Coronavirus, COVID-19, coronavirus disease 2019, BLM, bleomycin, Chemistry, ECM, extracellular matrix, Molecular Docking Simulation, Col Ⅰ, Collagen-Ⅰ, TGF-β, transform growth factor-β, Molecular Medicine, medicine.symptom, IL-1β, interleukin-1β, Inflammation, FRET, fluorescence resonance energy transfer, Antiviral Agents, Article, α-SMA, α-smooth muscle actin, In vivo, medicine, Animals, Humans, Protease Inhibitors, IC50, pulmonary fibrosis, SARS-CoV-2, Re, expiratory resistance, DHM, Dihydromyricetin, COVID-19, medicine.disease, Mice, Inbred C57BL, Mpro, main protease, Complementary and alternative medicine, SARS-CoV-2, Severe Acute Respiratory Syndrome coronavirus 2, FVC, forced vital capacity, Fn, fibronectin, Transforming growth factor
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المؤلفون: Ik Hwan Kim, Moon Kee Meang, Young Min Yoon, Ji Yong Lee, Byung Soo Youn, Tae Hee Lee, Han-Soo Kim, Lee Ji Eun, Yae Eun Park
المصدر: EBioMedicine
مصطلحات موضوعية: 0301 basic medicine, Research paper, Eupatilin, CD, chromone scaffold derivative, Stem cells, Idiopathic pulmonary fibrosis, chemistry.chemical_compound, Mice, 0302 clinical medicine, Fibrosis, Chromone scaffold, Transforming Growth Factor beta, Phosphorylation, Myofibroblasts, DHLF, diseased human lung fibroblast, Epithelial–mesenchymal transition, Cell Differentiation, General Medicine, Pirfenidone, Extracellular Matrix, 030220 oncology & carcinogenesis, Nintedanib, Dedifferentiation, Myofibroblast, medicine.drug, NASH, non-alcoholic steatohepatitis, BLM, bleomycin-induced lung fibrosis model, General Biochemistry, Genetics and Molecular Biology, Cell Line, 03 medical and health sciences, Bleomycin, In vivo, medicine, Hepatic Stellate Cells, IPF, idiopathic pulmonary fibrosis, Animals, Humans, Smad3 Protein, Flavonoids, business.industry, Fibroblasts, medicine.disease, CS, chromone scaffold, Disease Models, Animal, 030104 developmental biology, chemistry, Gene Expression Regulation, Latent TGF-beta Binding Proteins, Cell Transdifferentiation, Cancer research, business
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المؤلفون: Ya-jun Li, Jun-jia Chen, Ruirong Chen, Chuan-li Lu
المصدر: Carbohydrate Polymers
مصطلحات موضوعية: Corona virus disease 2019, Polymers and Plastics, Neutrophils, Drug Evaluation, Preclinical, polysaccharides, Smad2 Protein, 02 engineering and technology, IL-1RA, interleukin-1 receptor antagonist, Virus diseases, 01 natural sciences, Nrf2, nuclear factor-erythroid 2-related factor 2, Antioxidants, Mice, Pulmonary fibrosis, Pandemic, Epidemiology, BALF, bronchoalveolar lavage fluid, Mechanisms, Materials Chemistry, Medicine, TNF-α, Tumor necrosis factor-α, IL, Interleukin, Major complication, Medicine, Chinese Traditional, DOP, a neutral heteropolysaccharides from Dendrobium officinale, LMWF, Low-molecular weight fucoidan, AUF1, an adaptor protein AU-binding factor 1, BLM, bleomycin, FN, Fibronectin, Mw, molecular weight, POL, Total polysaccharide from O. lanpingensis, Mortality rate, Forkhead Box Protein O3, 021001 nanoscience & nanotechnology, PF, Pulmonary fibrosis, COVID-2019, Coronavirus disease-2019, FMP-1, a polysaccharide from Morchella esculenta, HEPF cell, human embryo pulmonary fibrosis cell, RNA, Long Noncoding, Coronavirus Infections, 0210 nano-technology, EMT, epithelial-mesenchymal transition, Signal Transduction, medicine.medical_specialty, Coronavirus disease 2019 (COVID-19), Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), MCP-1, Monocyte chemotactic protein 1, Pneumonia, Viral, 010402 general chemistry, Article, α-SMA, α-smooth muscle actin, Transforming Growth Factor beta1, Betacoronavirus, Bleomycin, ROS, reactive oxygen species, DANCR, differentiation antagonizing non-protein coding RNA, SOD, superoxide dismutase, FYGL-1, a neutral heteropolysaccharide from G. lucidum, ASP, total polysaccharides from Angelica sinensis, Animals, Humans, Heterogeneous Nuclear Ribonucleoprotein D0, Smad3 Protein, Pandemics, MS80, a novel sulfated oligosaccharide extracted from seaweed, ComputingMethodologies_COMPUTERGRAPHICS, MDA, malondialdehyde, Biological Products, Plants, Medicinal, pulmonary fibrosis, SARS-CoV-2, business.industry, OSM, Oncostatin M, Macrophages, BMSCs, bone marrow mesenchymal stem cells, TGF-β1, transforming growth factor β1, Organic Chemistry, Fungi, COVID-19, Seaweed, medicine.disease, Rats, 0104 chemical sciences, Disease Models, Animal, Immunology, RLE-6TN cell, alveolar type Ⅱ epithelial cell, business, IFN-γ, Interferon gamma, Phytotherapy
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المؤلفون: Ramakrishna Sistla, Satya Krishna Tirunavalli, Karthik Gourishetti, Taslim Babru Shaikh, Sai Balaji Andugulapati
المصدر: Phytomedicine
مصطلحات موضوعية: Pulmonary Fibrosis, ALP, Alkaline phosphatase, Pharmaceutical Science, EMT, epithelial to mesenchymal transition, Smad Proteins, CTCF, Corrected Total Cellular Fluorescence, NHLF, Normal human lung fibroblasts, Idiopathic pulmonary fibrosis, chemistry.chemical_compound, 0302 clinical medicine, Fibrosis, Transforming Growth Factor beta, Drug Discovery, Pulmonary fibrosis, BLM, Bleomycin, Myofibroblasts, 0303 health sciences, Cell Differentiation, Pirfenidone, respiratory system, Genistein, ECM, extracellular matrix, Extracellular Matrix, HIF1-α, Hypoxia-Inducible Factor 1-α, 030220 oncology & carcinogenesis, Molecular Medicine, Nintedanib, Female, Collagen, TIMP, Tissue inhibitory metalloproteinase, E-cad, E-cadherin, LDH, Lactic Acid Dehydrogenase, hr, hour, medicine.drug, TGF-β, FN-I, Fibronectin-I, Epithelial-Mesenchymal Transition, CTGF, Connective tissue growth factor: RT-qPCR, Reverse transcriptase quantitative PCR, Bleomycin, Article, 03 medical and health sciences, COL3Al, Collagen3α1, LOXL-2, Lysyl oxidase-like2, BALF, Bronchoalveolar lavage Fluid (BALF), In vivo, Abbreviations: BCA, Biochanin-A, medicine, Animals, Humans, PCMLS, Precision cut mouse lung slices, Rats, Wistar, 030304 developmental biology, Pharmacology, Inflammation, α-SMA, a-smooth muscle actin, rTGF-β1, recombinant transforming growth factor-beta 1, business.industry, IPF, Idiopathic pulmonary fibrosis, SRB, sulforhodamine-B, Reproducibility of Results, medicine.disease, DHLF, Diseased (IPF) human lung fibroblasts, FDA, Food and Drug Administration, respiratory tract diseases, Mice, Inbred C57BL, BALF, Complementary and alternative medicine, chemistry, COL1A1, Collagen1α1, Cancer research, Extra-cellular matrix, business, Ex vivo
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المؤلفون: C. Sowmya, S. Chennakesavulu, C. Suryaprakash Reddy, E. Bhargav, A. Mishra, Akkiraju Sudheer
المصدر: Asian Journal of Pharmaceutical Sciences, Vol 13, Iss 1, Pp 91-100 (2018)
Asian Journal of Pharmaceutical Sciencesمصطلحات موضوعية: Budesonide, HDPE, High density polyethylene, education, EPC, Egg phosphatidyl choline, FPF, Fine particle fraction, Pharmaceutical Science, Pharmacology, 030226 pharmacology & pharmacy, 03 medical and health sciences, Idiopathic pulmonary fibrosis, Hydroxyproline, chemistry.chemical_compound, 0302 clinical medicine, Idiopathic Pulmonary fibrosis, BLM, Bleomycin, medicine, Original Research Article, SLS, Sodium lauryl sulphate, M2, Mixture of BUD & COL (Optimized formulation), PVC, Poly vinyl chloride, PBS, Saline Phosphate buffer, UV, Ultraviolet, Liposome, Lung, DE, Drug entrapment, Liposomal dry powder inhaler, lcsh:RM1-950, medicine.disease, MDI's, Metered Dose Inhalers, MMAD, Mean Median Aerodynamic diameter, Pulmonary drug delivery, Dry-powder inhaler, DPI, Dry Powder Inhaler, medicine.anatomical_structure, lcsh:Therapeutics. Pharmacology, chemistry, 030220 oncology & carcinogenesis, Drug delivery, Mannitol, Colchicine, medicine.drug
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المؤلفون: Marika Cordaro, Giuseppe Bruschetta, Jose Maria Zubelia, Rosalia Crupi, Daniela Impellizzeri, Rosalba Siracusa, Emanuela Esposito, Virginia Motilva, Salvatore Cuzzocrea, Antonio Montero Alcaide, Elena Talero
المصدر: British Journal of Nutrition. 114:853-865
مصطلحات موضوعية: Male, Pulmonary Fibrosis, Xanthones, Medicine (miscellaneous), Apoptosis, Respiratory Mucosa, Lung injury, Pharmacology, Resveratrol, medicine.disease_cause, Antioxidants, Random Allocation, chemistry.chemical_compound, Stilbenes, Pulmonary fibrosis, medicine, Animals, Vitis, Mangiferin, Lung, Mice, Inbred ICR, Mangifera, Nutrition and Dietetics, medicine.diagnostic_test, Plant Extracts, Nitrotyrosine, Anti-Inflammatory Agents, Non-Steroidal, Polyphenols, food and beverages, medicine.disease, Apoptosis, BAL bronchoalveolar lavage, BLM bleomycin, COX-2 cyclo-oxygenase-2, DHQ dihydroquercetin, IPF idiopathic pulmonary fibrosis, Inflammation, Lung injury, MPO myeloperoxidase, Oxidative stress, PARP poly (ADP-ribose) polymerase, Polyphenols, ROS reactive oxygen species, iNOS inducible NO synthase, pERK phosphorylated extracellular signal-regulated kinase, Animals, Anti-Inflammatory Agents Non-Steroidal, Antioxidants, Apoptosis, Lung, Male, Mangifera, Mice Inbred ICR, Neutrophil Infiltration, Plant Extracts, Plant Leaves, Polyphenols, Pulmonary Fibrosis, Quercetin, Random Allocation, Respiratory Mucosa, Stilbenes, Vitis, Xanthones, Dietary Supplements, Disease Models Animal, Plant Leaves, Disease Models, Animal, Bronchoalveolar lavage, Neutrophil Infiltration, chemistry, Dietary Supplements, Immunology, Quercetin, Oxidative stress
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المؤلفون: Lian-Di Kan, Liu-Cheng Li
المصدر: Journal of Ethnopharmacology
مصطلحات موضوعية: PQ, paraquat, Active ingredient, NQO1, NAD(P)H:quinone oxidoreductase 1, GC-MS, gas chromatograph-mass spectrometer, HSYA, hydroxy safflor yellow A, Traditional Chinese medicine, TNF-α, tumor necrosis factor-α, ESA, eclipta saponin A, Triptolide (PubChem CID: 107985), BA, boswellic acids, 0302 clinical medicine, LPO, lipid peroxide, HLF, human lung fibroblasts, Drug Discovery, Pulmonary fibrosis, CCl4, carbon tetrachloride, GSH, glutathione, Medicine, GR, glutathione reductase, Glycosides, ET, endothelin, PARP, poly ADP-ribose polymerase, HO-1, heme oxygenase-1, EGCG, epigallocatechin-3-gallate, FB, fibroblasts, LPA1, lysophosphatidic acid receptor 1, LDH, lactate dehydrogenase, Drug discovery, Tanshinone IIA (PubChem CID: 164676), Celastrol (PubChem CID: 122724), PMVEC, pulmonary microvascular endothelial cells, MCP-1, monocyte chemoattractant protein-1, Andro, Andrographolide, Res, resveratrol, ECM, extracellular matrix, 030220 oncology & carcinogenesis, EndoMT, endothelial-mesenchymal transition, iNOS, inducible nitric oxide synthase, p-Smads, phosphorylated Smads, AMs, alveolar macrophages, Mechanism, TIMP, tissue inhibitor of metalloproteinase, HMGB1, high-mobility group box 1, medicine.medical_specialty, SAA, salvianolic acid A, DSQRL, Decoction for Strengthening Qi and Replenishing Lung, PF, pulmonary fibrosis, CP, cyclophosphamide, Quercetin (PubChem CID: 5280343), HSM, Hirsutella sinensis mycelium, Article, 03 medical and health sciences, Humans, miR, miRNA, MFb, myofibroblasts, SARS, severe acute respiratory syndrome, Tan IIA, tanshinone IIA, Intensive care medicine, ARDS, acute respiratory distress syndrome, FN, fibronectin, NS, Nigella sativa L, Pharmacology, MDA, malondialdehyde, HELFs, human embryonic lung fibroblast, SOD, superoxide dismutases, GBA, gambogic acid, Medical practice, medicine.disease, SP-D, surfactant protein-D, ANG, angiotensin, IL, interleukin, Clinical trial, RPF, rapid pulmonary fibrosis, 030104 developmental biology, Eclipta saponin A (PubChem CID: 476537), DBTG, total glucosides of Danggui-Buxue-Tang, TAL, triterpene acids of loquat, CAT, catalase, Paeoniflorin (PubChem CID: 442534), 0301 basic medicine, ALI, acute lung injury, LC3A/B, light chains 3A/B, NLRP, NOD-like receptor, Pulmonary Fibrosis, Hyp, hydroxyproline, MPO, myeloperoxidase, PDGF, platelet-derived growth factor, T-AOC, total antioxidant capacity, ACE, angiotensin converting enzyme, BALF, bronchoalveolar lavage fluid, Keap, Kelch like ECH-associated protein, Medicine, Chinese Traditional, NF-κB, nuclear factor kappa B, BLM, bleomycin, SY, safflor yellow, NOX, NADPH oxidase, VEGF, vascular endothelial growth factor, MMP, matrix metalloproteinase, Curcumin (PubChem CID: 969516), LOX, lipooxygenase, Nrf2, nuclear factor erythroid 2-related factor, TGF-β1, transforming growth factor-β1, Flavanones, LPS, lipopolysaccharide, Quercetin, TCM, traditional Chinese medicine, EMT, epithelial-mesenchymal transition, AEC, alveolar epithelial cells, Col-I, collagen types I, OM, Oxymatrine, mKG, Modified Kushen Gancao Formula, RPFS, Renshen pingfei decoction, BECs, bronchial epithelial cells, CTGF, connective tissue growth factor, α-SMA, α-smooth muscle actin, Lung Disorder, GCA, glycyrrhizic acid, OVA, ovalbumin, ROS, reactive oxygen species, Phenols, BAI, Baicalein, Animals, IFN, interferon, PG, prostaglandin, YPF-G, total glycoside of Yupingfeng, THP, tetrahydropalmatine, TPL, triptolide, Herb, business.industry, Mechanism (biology), Terpenes, FEV1, forced expiratory volume in one second, Paclitaxel (PubChem CID: 36314), HC, Houttuynia cordata, GA, gallic acid, EOCR, essential oil of Citrus reticulata, GPx, glutathione peroxidases, TQABDA, Tonifying Qi, Activating Blood and Dispersing Accumulation, IR, irradiation, Baicalein (PubChem CID: 5281605), Processing methods, FGF, fibroblast growth factor, COX, cyclooxygenase, PTX, paclitaxel, Tectorigenin (PubChem CID: 5281811), α-terpineol (PubChem CID: 17100), MAPK, mitogen-activated protein kinases, XRT, x-ray treatment, FVC, forced vital capacity, VASH, Vasohibin, COL1A1, procollagen type 1 a1, business, Phytotherapy, HPMECs, human pulmonary microvascular endothelial cells
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المؤلفون: Meng-Li Chen, Ming Hung Chan, Wing Keung Liu, Florence W K Cheung, Chun-Tao Che, Yick Hin Ling, Pak K. Hui, Siu-Po Ip
المصدر: Journal of Ethnopharmacology
مصطلحات موضوعية: Male, Pathology, Pulmonary Fibrosis, CE, Cordyceps powder extract in culture medium, Rats, Sprague-Dawley, Extracellular matrix, Idiopathic pulmonary fibrosis, chemistry.chemical_compound, BALF, bronchoalveolar lavage fluid, Drug Discovery, Medicine, Medicine, Chinese Traditional, BLM, bleomycin, Deoxyadenosines, biology, Cadherins, CS, Cordyceps sinensis, ECM, extracellular matrix, medicine.anatomical_structure, Matrix Metalloproteinase 9, MMP, matrix metalloproteinases, Collagen, EMT, epithelial–mesenchymal transition, Cordyceps sinensis, Myofibroblast, medicine.medical_specialty, TIMP, tissue inhibitors of metalloproteinases, Protective Agents, Bleomycin, Article, Bleomycin-induced lung fibrosis, Transforming Growth Factor beta1, ROS, reactive oxygen species, Traditional Chinese medicine, Cordycepin, Cell Line, Tumor, Animals, Humans, Vimentin, IPF, idiopathic pulmonary fibrosis, TGF-β1, transforming growth factor beta-1, Pharmacology, CS1, low-dose CS powder suspension treatment, Cordyceps, Tissue Inhibitor of Metalloproteinase-1, Lung, business.industry, medicine.disease, biology.organism_classification, Rats, chemistry, business, CS2, high-dose CS powder suspension treatment, Transforming growth factor
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10دورية أكاديمية
المؤلفون: Chennakesavulu S; Pharmacy Department, NDDS Laboratory, Donors Plaza, Faculty of Technology and Engineering, The Maharaja Sayajirao University of Baroda, Gujarat, India., Mishra A; Pharmacy Department, NDDS Laboratory, Donors Plaza, Faculty of Technology and Engineering, The Maharaja Sayajirao University of Baroda, Gujarat, India., Sudheer A; Pharmacology Department, Faculty of Technology and Engineering, The Maharaja Sayajirao University of Baroda, Gujarat, India., Sowmya C; Center for Pharmaceutical Research, Pharmaceutics Department, Raghavendra Institute of Pharmaceutical Education and Research, Anantapuramu 515721, Andhra Pradesh, India., Suryaprakash Reddy C; Center for Pharmaceutical Research, Pharmaceutics Department, Raghavendra Institute of Pharmaceutical Education and Research, Anantapuramu 515721, Andhra Pradesh, India., Bhargav E; Center for Pharmaceutical Research, Pharmaceutics Department, Raghavendra Institute of Pharmaceutical Education and Research, Anantapuramu 515721, Andhra Pradesh, India.
المصدر: Asian journal of pharmaceutical sciences [Asian J Pharm Sci] 2018 Jan; Vol. 13 (1), pp. 91-100. Date of Electronic Publication: 2017 Aug 18.
نوع المنشور: Journal Article
بيانات الدورية: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101535338 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2221-285X (Electronic) Linking ISSN: 18180876 NLM ISO Abbreviation: Asian J Pharm Sci Subsets: PubMed not MEDLINE
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