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1Extracellular cathepsin Z signals through the α5 integrin and augments NLRP3 inflammasome activation
المؤلفون: Justin A. MacDonald, Catherine J. Greene, Christina F. Sandall, Neil McKenna, Rhiannon I. Campden, Jose A. Chiriboga, Robin M. Yates, Devin Aggarwal, Amy L. Warren, Corey R. Arnold
المصدر: The Journal of Biological Chemistry
مصطلحات موضوعية: Inflammasomes, Interleukin-1beta, Integrin alpha5, Biochemistry, Mice, 0302 clinical medicine, 0303 health sciences, biology, Chemistry, interleukin-1 (IL-1), Inflammasome, Silicon Dioxide, PMA, phorbol myristate acetate, Cysteine protease, 3. Good health, Cell biology, silica, LPS, lipopolysaccharide, medicine.symptom, RGD, arginine-glycine-asparigine, Research Article, medicine.drug, integrin, Silicosis, Integrin, Inflammation, MSU, monosodium urate, MS, multiple sclerosis, EAE, encephalomyelitis, 03 medical and health sciences, NLRP3, FBS, fetal bovine serum, inflammasome, NLR Family, Pyrin Domain-Containing 3 Protein, medicine, Extracellular, Animals, APC, antigen-presenting cells, Molecular Biology, BMDC, bone marrow-derived dendritic cells, 030304 developmental biology, Cathepsin, Cathepsin Z, Cell Biology, arginine-glycine-aspartic acid (RGD) domain, Cell culture, biology.protein, 030217 neurology & neurosurgery
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b27c210c61616d4955d5ffecfb0fa14
https://doi.org/10.1016/j.jbc.2021.101459 -
2
المؤلفون: Sombetzki, Martina, Fuchs, Claudia D., Fickert, Peter, Österreicher, Christoph H., Mueller, Michaela, Claudel, Thierry, Loebermann, Micha, Engelmann, Robby, Langner, Cord, Sahin, Emine, Schwinge, Dorothee, Guenther, Nina D., Schramm, Christoph, Mueller-Hilke, Brigitte, Reisinger, Emil C., Trauner, Michael
المصدر: Journal of Hepatology
مصطلحات موضوعية: Schistosoma mansoni infection, Liver Cirrhosis, Anti-inflammatory/anti-fibrotic therapy, Cholagogues and Choleretics, T-Lymphocytes, BMDC, bone marrow derived dendritic cells, Liver fibrosis, Lymphocyte Activation, M-CSF, macrophage colony-stimulating factor, UDCA, ursodeoxycholic acid, Mice, norUDCA, 24-nor-ursodeoxycholic acid, HP, hydroxyproline, B. glabrata, Biomphalaria glabrata, ALT, alanine aminotransferase, Animals, ComputingMethodologies_COMPUTERGRAPHICS, Inflammation, S. mansoni, Schistosoma mansoni, BMDM, bone marrow derived macrophages, Granuloma, Hepatology, Ursodeoxycholic Acid, Immunohistochemistry, Bile acids, Schistosomiasis mansoni, Disease Models, Animal, AP, alkaline phosphatase, Treatment Outcome, Abcb4/Mdr2, canalicular phospholipid export pump/multidrug resistance protein 2, Drug Monitoring, Hepatic granulomas, Research Article
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3
المؤلفون: Rossana Zaru, Alexander J. Edgar, Colin Watts, Matthias Trost
المصدر: Bioscience Reports, Vol 34, Iss 1, p e00091 (2014)
Bioscience Reportsمصطلحات موضوعية: lcsh:Life, lcsh:QR1-502, MIP1α, macrophage inflammatory protein 1α, DSTT, Division of Signal Transduction Therapy, Biochemistry, DMEM, Dulbecco’s modified Eagle’s medium, lcsh:Microbiology, Mice, DC, dendritic cell, 0302 clinical medicine, BIX 02565, Stable isotope labeling by amino acids in cell culture, Nucleotide, chemistry.chemical_classification, 0303 health sciences, Nucleotides, Kinase, Pteridines, PI3K, phosphoinositide-3 kinase, Azepines, PIP3, phosphatidylinositol-3,4,5-triphosphate, 3. Good health, Amino acid, TNFα, tumour necrosis factor α, 030220 oncology & carcinogenesis, Biotinylation, JNK, c-Jun N-terminal kinase, LPS, lipopolysaccharide, Phosphorylation, TLR, Toll-like receptor, ERM, ezrin, radixin and moesin, PKB, protein kinase B, BI-D1870, IL6, interleukin 6, Ste-20 like kinase, Biophysics, S6, SDC, spleen dendritic cells, Protein Serine-Threonine Kinases, Biology, ERK, extracellular-signal-regulated kinase, Ribosomal Protein S6 Kinases, 90-kDa, 03 medical and health sciences, GSK3, glycogen synthase kinase 3, Animals, dendritic cells, Protein kinase A, Molecular Biology, BMDC, bone marrow-derived dendritic cells, 030304 developmental biology, EGF, epidermal growth factor, Original Paper, Staining and Labeling, FCS, foetal calf serum, Cell Biology, RSK, p90 ribosomal S6 kinase, lcsh:QH501-531, Enzyme, chemistry, Benzimidazoles, SILAC, stable isotope labelling by amino acids in cell culture, p90 ribosomal S6 kinase (Rsk), MAPK, mitogen-activated protein kinase, protein kinase B (PKB)
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::12fae0d7e2b25d40b4ebdc7cd6e124c5
https://doi.org/10.1042/bsr20130094 -
4مورد إلكتروني
المصدر: DTIC
مصطلحات الفهرس: Medicine and Medical Research, ANTIGENS, CYTOKINES, CELLS(BIOLOGY), GROWTH(PHYSIOLOGY), HYPOTHESES, MICE, NEOPLASMS, OBSERVATION, SKILLS, BMDC(BONE MARROW DERIVED DENDRITIC CELLS), NEUROFIBROMATOSIS TYPE 1, ANTIGEN PRESENTATION, ANTITUMOR, INNATE IMMUNITY, NKT CELLS, Text
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5مورد إلكتروني
المصدر: DTIC
مصطلحات الفهرس: Biochemistry, Anatomy and Physiology, Medicine and Medical Research, Microbiology, APOPTOSIS, STREPTOCOCCAL PNEUMONIA, BACTERIA, CELLS, PEPTIDES, POLYSACCHARIDES, LIGANDS, STRAINS(BIOLOGY), ENCAPSULATION, RESPONSE(BIOLOGY), MICE, IMMUNITY, DENDRITIC STRUCTURE, BONE MARROW, RECEPTOR SITES(PHYSIOLOGY), PHAGOCYTES, IODIDES, CYTOKINES, REPRINTS, FLUORESCENCE, TLR(TOLL LIKE RECEPTORS), DC(DENDRITIC CELLS), MYD88(MYELOID DIFFERENTIATION FACTOR 88), BMDC(BONE MARROW DERIVED DENDRITIC CELLS), PG(PEPTIDOGLYCAN), PI(PROPIDIUM IODIDE), FMK(FLUOROMETHYLKETONE), CD95L(CD95 LIGANDS), CM DIL(CHLOROMETHYLBENZAMIDO DERIVATIVE OF DIL), CT(CYTOCHALASIN), MFI(MEAN FLUORESCENCE INTENSITY), MUTANTS, PNEUMOLYSIN, DELAYED ONSET, FLOW CYTOMETRY, CELLULAR CASPASE ACTIVITY, PHAGOCYTIC CAPACITY, CYTOKINE ELISA, Text