المؤلفون: CA Fielding, P Sabberwal, JC Williamson, EJD Greenwood, TWM Crozier, W Zelek, J Seow, C Graham, I Huettner, JD Edgeworth, D Price, BP Morgan, K Ladell, M Eberl, IR Humphreys, B Merrick, K Doores, SJ Wilson, PJ Lehner, ECY Wang, RJ Stanton

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::cf0a5d918f62649dcec327d6a21d9f50
https://doi.org/10.1101/2021.04.06.438630

المؤلفون: Aj Day, Sj Clark, Bp Morgan, I Zambrano, P. N. Bishop, S Hakobyan

المصدر: Acta Ophthalmologica. 87

مصطلحات موضوعية: chemistry.chemical_classification, Retinal pigment epithelium, genetic structures, General Medicine, Biology, Molecular biology, Bruch's membrane, eye diseases, law.invention, Complement system, Pathogenesis, Ophthalmology, Enzyme, medicine.anatomical_structure, Biochemistry, chemistry, law, Factor H, Recombinant DNA, medicine, Alternative complement pathway, sense organs

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::6e8b7641bc89205f4ace57b35af98d07
https://doi.org/10.1111/j.1755-3768.2009.2222.x

المؤلفون: Denise Vilarinho Tambourgi, Bp, Morgan, Rm, Andrade, Fc, Magnoli, Cw, Den Berg

المصدر: Europe PubMed Central

مصطلحات موضوعية: Erythrocytes, Phosphoric Diester Hydrolases, Erythrocyte Membrane, Metalloendopeptidases, Neuraminidase, Spider Venoms, Spiders, Complement System Proteins, U937 Cells, In Vitro Techniques, Hemolysis, Enzyme Activation, Jurkat Cells, Animals, Humans, Protease Inhibitors, Glycophorins, K562 Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::c57b7b501bc9dbaf9948c58e3e8e8571
https://pubmed.ncbi.nlm.nih.gov/10627480

المؤلفون: Sj, Piddlesden, Mk, Storch, Hibbs M, Am, Freeman, Hans Lassmann, Bp, Morgan

المصدر: Europe PubMed Central

مصطلحات موضوعية: Male, Encephalomyelitis, Autoimmune, Experimental, Rats, Inbred Lew, Receptors, Complement 3b, Animals, Antibodies, Recombinant Proteins, Rats

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::7a97c9cd3446102a05f95ed8c11c764f
https://pubmed.ncbi.nlm.nih.gov/8189065

المؤلفون: David J.A. Evans, BP Morgan, R Powell, OB Spiller, Ian Goodfellow

المصدر: Immunopharmacology. 49:67

مصطلحات موضوعية: Pharmacology, Echovirus, Downregulation and upregulation, Factor H, Direct binding, medicine, COMPLEMENT REGULATORS, Biology, Complement mediated lysis, medicine.disease_cause, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::90ea1918d3484bef41d3f4e0d85a40bd
https://doi.org/10.1016/s0162-3109(00)80191-5

المؤلفون: kevin james marchbank, Bp, Morgan, Cw, Den Berg

المصدر: Europe PubMed Central

مصطلحات موضوعية: Cytotoxicity, Immunologic, Complement Inactivator Proteins, Leukemia, Experimental, Membrane Glycoproteins, Phosphoric Diester Hydrolases, Phosphatidylinositol Diacylglycerol-Lyase, Blotting, Western, chemical and pharmacologic phenomena, CD59 Antigens, Complement System Proteins, Up-Regulation, Antigens, CD, Dactinomycin, Tumor Cells, Cultured, Animals, Humans, Tetradecanoylphorbol Acetate, Cycloheximide, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::23a2a041c499df6900b362183de3a483
http://europepmc.org/abstract/med/7543447

المؤلفون: Mb, Powell, kevin james marchbank, Nk, Rushmere, Cw, Den Berg, Bp, Morgan

المصدر: Europe PubMed Central

مصطلحات موضوعية: Cytotoxicity, Immunologic, Mice, Inbred BALB C, DNA, Complementary, Base Sequence, Blotting, Western, Molecular Sequence Data, Chromosome Mapping, CD59 Antigens, Blotting, Northern, Polymerase Chain Reaction, Rats, Mice, Gene Expression Regulation, Animals, Humans, Amino Acid Sequence, Cloning, Molecular, In Situ Hybridization, Fluorescence

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid_dedup__::5e13931f025b48f2e10732f44ac748f9
http://europepmc.org/abstract/med/9029105

المؤلفون: Rivas VN; Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 1060 William Moore Dr, Raleigh, NC, 27607, USA.; Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California-Davis, Davis, CA, USA., Crofton AE; Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California-Davis, Davis, CA, USA., Jauregui CE; Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California-Davis, Davis, CA, USA., Wouters JR; Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California-Davis, Davis, CA, USA., Yang BS; Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California-Davis, Davis, CA, USA., Wittenburg LA; Department of Surgical and Radiological Sciences, School of Veterinary Medicine, University of California-Davis, Davis, CA, USA., Kaplan JL; Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California-Davis, Davis, CA, USA., Hwee DT; Research and Non-Clinical Development, Cytokinetics, Inc., South San Francisco, CA, USA., Murphy AN; Research and Non-Clinical Development, Cytokinetics, Inc., South San Francisco, CA, USA., Morgan BP; Research and Non-Clinical Development, Cytokinetics, Inc., South San Francisco, CA, USA., Malik FI; Research and Non-Clinical Development, Cytokinetics, Inc., South San Francisco, CA, USA., Harris SP; Department of Physiology, University of Arizona, Tucson, AZ, USA., Stern JA; Department of Clinical Sciences, College of Veterinary Medicine, North Carolina State University, 1060 William Moore Dr, Raleigh, NC, 27607, USA. jastern@ncsu.edu.; Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California-Davis, Davis, CA, USA. jastern@ncsu.edu.

المصدر: Scientific reports [Sci Rep] 2024 May 27; Vol. 14 (1), pp. 12038. Date of Electronic Publication: 2024 May 27.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Cardiomyopathy, Hypertrophic*/drug therapy , Cardiac Myosins*/metabolism, Animals ; Cats ; Cat Diseases/drug therapy ; Male ; Female ; Ventricular Outflow Obstruction/drug therapy ; Systole/drug effects ; Echocardiography ; Cross-Over Studies

المؤلفون: Collibee SE; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., Romero A; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., Muci AR; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., Hwee DT; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., Chuang C; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., Hartman JJ; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., Motani AS; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., Ashcraft L; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., DeRosier A; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., Grillo M; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., Lu Q; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., Malik FI; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., Morgan BP; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States.

المصدر: Journal of medicinal chemistry [J Med Chem] 2024 May 23; Vol. 67 (10), pp. 7859-7869. Date of Electronic Publication: 2024 Mar 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Myocardial Contraction*/drug effects , Troponin*/metabolism, Animals ; Male ; Rats ; Myocytes, Cardiac/metabolism ; Myocytes, Cardiac/drug effects ; Rats, Sprague-Dawley ; Structure-Activity Relationship

المؤلفون: Romero A; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., Ashcraft L; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., Chandra A; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., DiMassa V; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., Cremin P; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., Collibee SE; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., Chuang C; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., Hartman J; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., Hwee DT; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., St Jean D; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., Malinowski J; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., DeBenedetto M; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., Moebius D; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., Payette J; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., Vargas R; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., Yeoman J; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., Motani A; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., Reagan J; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., Malik FI; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States., Morgan BP; Cytokinetics, Inc., 350 Oyster Point Boulevard, South San Francisco, California 94080, United States.

المصدر: Journal of medicinal chemistry [J Med Chem] 2024 May 23; Vol. 67 (10), pp. 7825-7835. Date of Electronic Publication: 2024 May 10.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE

مواضيع طبية MeSH: Myocardial Contraction*/drug effects, Humans ; Animals ; Cardiovascular Diseases/drug therapy ; Rats ; Structure-Activity Relationship ; Male ; Drug Discovery ; Troponin/metabolism ; Mice ; Rats, Sprague-Dawley ; Sulfonamides/pharmacology ; Sulfonamides/pharmacokinetics ; Sulfonamides/chemistry ; Sulfonamides/therapeutic use ; Sulfonamides/chemical synthesis