المؤلفون: Rodríguez Asiain, Arantzazu

المساهمون: University/Department: Universitat Autònoma de Barcelona. Departament de Bioquímica i Biologia Molecular

مرشدي الرسالة: Lizcano de Vega, José Miguel

المصدر: TDX (Tesis Doctorals en Xarxa)

مصطلحات موضوعية: BRSK, Neurona, Sinapsi, Ciències de la Salut

وصف الملف: application/pdf

URL الوصول: http://hdl.handle.net/10803/96911

المؤلفون: Natalia Shpiro, Maria Stella Ritorto, Kei Sakamoto, Dario R. Alessi, Vanessa P. Houde, Robert Gourlay, Joby Varghese, Paul Davies

المصدر: Biochemical Journal

مصطلحات موضوعية: AICAR, 5-amino-4-imidazolecarboxamide riboside, PDK1, phosphoinositide-dependent kinase 1, ACC, acetyl-CoA carboxylase, AMP-Activated Protein Kinases, Mitogen-activated protein kinase kinase, Biochemistry, 5-amino-4-imidazolecarboxamide riboside (AICAR), MAP2K7, Ribosomal s6 kinase, Mice, PKA, cAMP-dependent protein kinase, Serine, ASK1, Phosphorylation, MAPKAPK, MAPKAP (MAPK-activated protein) kinase, HA, haemagglutinin, DMEM, Dulbecco's modified Eagle's medium, biology, EDL, extensor digitorum longus, HRP, horseradish peroxidase, RSK, ribosomal S6 kinase, Cell biology, GAPDH, glyceraldehyde-3-phosphate dehydrogenase, SAD-A/SAD-B kinase, BDNF, brain-derived neurotrophic factor, ACTH, adrenocorticotropic hormone, NUAK1, NUAK family, SNF1-like kinase, MARK4, MAP/microtubule affinity-regulating kinase 4, signal transduction, PI3K, phosphoinositide 3-kinase, raptor, regulatory associated protein of mTOR, Research Article, PH, pleckstrin homology, Molecular Sequence Data, Protein Prenylation, mTOR, mammalian target of rapamycin, Protein Serine-Threonine Kinases, ERK, extracellular-signal-regulated kinase, SIK3, salt-inducible kinase 3, ER, endoplasmic reticulum, HEK, human embryonic kidney, TBC1D1, TBC (Tre-2/Bub2/Cdc16) domain family, member 1, Animals, Humans, HSP90, heat-shock protein 90, Amino Acid Sequence, Cysteine, c-Raf, ARK5, AMPK-related protein kinase 5, phenformin, Molecular Biology, BiP, immunoglobulin heavy-chain-binding protein, MAP kinase kinase kinase, AMP-activated protein kinase-related kinase (AMPK-related kinase), Adenylate Kinase, AMPK, Cell Biology, MEF, mouse embryonic fibroblast, Molecular biology, STRAD, STE20-related kinase adaptor, AMPK, AMP-activated protein kinase, HEK293 Cells, monoclonal antibody, biology.protein, Cyclin-dependent kinase 9, BRSK, BR serine/threonine kinase, MAPK, mitogen-activated protein kinase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fe36ddd49d60988f3b36857bd507191
https://doi.org/10.1042/bj20131324

المؤلفون: Jinhua Wang, Alan R. Prescott, Nathanael S. Gray, Ryan Traynor, Hai-Tsang Huang, Sourav Banerjee, Sara J. Buhrlage, Xianming Deng, Wenjun Zhou, Dario R. Alessi

المصدر: Biochemical Journal

مصطلحات موضوعية: PEI, polyethylenimine, Drug Evaluation, Preclinical, NUAK1, ACC, acetyl-CoA carboxylase, Biochemistry, DMEM, Dulbecco’s modified Eagle’s medium, Substrate Specificity, MAP2K7, Mice, AMP-Activated Protein Kinase Kinases, Cell Movement, Neoplasms, Anilides, ASK1, MYPT1, myosin phosphate-targeting subunit 1, MAPK1, sucrose-non-fermenting protein kinase/AMPKrelated protein kinase (SNARK), Cells, Cultured, HA, haemagglutinin, Benzodiazepinones, PP1, protein phosphatase 1, Cell biology, liver kinase B1 (LKB1), kinase profiling, NF-κB, nuclear factor κB, Research Article, kinase inhibitor, BRSK, brain-specific kinase, AMPK-related kinase 5 (ARK5), Protein Serine-Threonine Kinases, Biology, Heterocyclic Compounds, 4 or More Rings, HEK, human embryonic kidney, LKB1, liver kinase B1, AMP-activated protein kinase (AMPK), Animals, Humans, c-Raf, Protein kinase A, Protein Kinase Inhibitors, Molecular Biology, Cell Proliferation, MAPK14, Tumor Suppressor Proteins, Cyclin-dependent kinase 2, Cell Biology, SIK, salt-induced kinase, MEF, mouse embryonic fibroblast, MARK, microtubule-affinity-regulating kinase, Enzyme Activation, Repressor Proteins, AMPK, AMP-activated protein kinase, HEK293 Cells, Pyrimidines, biology.protein, myosin phosphate-targeting subunit 1(MYPT1), Protein Kinases

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65d07d9ac0f6f4c4a17a25a75be92725
https://doi.org/10.1042/bj20131152

المؤلفون: Simon A, Hawley, Fiona A, Ross, Graeme J, Gowans, Priyanka, Tibarewal, Nicholas R, Leslie, D Grahame, Hardie

المصدر: Biochemical Journal

مصطلحات موضوعية: Models, Molecular, PTEN, phosphatase and tensin homologue deleted on chromosome 10, STRADα, Ste20-related adapter protein-α, tumour suppressor, Protein Conformation, BRSK, brain-specific kinase, AICAR, 5-amino-4-imidazolecarboxamide riboside, Down-Regulation, ACC, acetyl-CoA carboxylase, AMP-Activated Protein Kinases, MO25α, mouse protein-25α, DMEM, Dulbecco’s modified Eagle’s medium, HEK, human embryonic kidney, LKB1, liver kinase B1, ST loop, serine/threonine-rich loop, AMP-activated protein kinase (AMPK), GSK3, glycogen synthase kinase 3, S6K1, S6 kinase 1, Animals, Humans, cancer, Amino Acid Sequence, Phosphorylation, IGF-1, insulin-like growth factor 1, Akt, NEAA, non-essential amino acid, PTEN Phosphohydrolase, PKA, protein kinase A (cAMP-dependent protein kinase), mTORC1, mammalian (or mechanistic) target of rapamycin complex 1, MEF, mouse embryonic fibroblast, WT, wild-type, Protein Structure, Tertiary, Gene Expression Regulation, Neoplastic, AMPK, AMP-activated protein kinase, HEK293 Cells, cross-talk, CaMKK, calmodulin-dependent kinase kinase β, Proto-Oncogene Proteins c-akt, PI3K, phosphoinositide 3-kinase, Protein Binding, Research Article

URL الوصول: https://explore.openaire.eu/search/publication?articleId=pmid________::8369fb16e1bedfa5ac5bda12a5ea49ec
https://pubmed.ncbi.nlm.nih.gov/24467442

المؤلفون: D. Grahame Hardie, Sarah Fogarty, Kevin A. Green, Simon A. Hawley, Nazan Saner, Kirsty J. Mustard

المصدر: Biochemical Journal

مصطلحات موضوعية: CaMK, Ca2+/calmodulin-dependent protein kinase, AICAR, 5-amino-4-imidazolecarboxamide riboside, ACC, acetyl-CoA carboxylase, Mitogen-activated protein kinase kinase, AMP-Activated Protein Kinases, CaMKK, Ca2+/calmodulin-dependent protein kinase kinase, Ca2+/calmodulin-dependent protein kinase kinase (CaMKK), Biochemistry, MAP2K7, 0302 clinical medicine, Adenosine Triphosphate, Phenformin, GST, glutathione transferase, Cyclic AMP, ASK1, Phosphorylation, Calcimycin, GFP, green fluorescent protein, 0303 health sciences, biology, Chemistry, UBA, ubiquitin-associated, SIK, salt-inducible kinase, 3. Good health, Cell biology, Adenosine Diphosphate, FBS, foetal bovine serum, NUAK, SNF1 (sucrose-non-fermenting kinase-1)-like kinase, Protein Binding, Research Article, BRSK, brain-specific kinase, Molecular Sequence Data, MO25, mouse protein 25, Calcium-Calmodulin-Dependent Protein Kinase Kinase, AMPactivated protein kinase-related kinase (ARK), STRAD, Ste20-related adaptor, Cell Line, 03 medical and health sciences, HEK, human embryonic kidney, ARK, AMPK-related kinase, AMP-activated protein kinase (AMPK), Humans, Immunoprecipitation, Amino Acid Sequence, Protein kinase A, Molecular Biology, 030304 developmental biology, MAPK14, MARK, microtubule affinity-regulating kinase, Ionophores, Sequence Homology, Amino Acid, Cyclin-dependent kinase 2, AMPK, Cell Biology, TBS, Tris-buffered saline, Calmodulin dependent protein kinase, AMPK, AMP-activated protein kinase, Ca2+/calmodulindependent protein kinase (CaMK), biology.protein, Calcium, 030217 neurology & neurosurgery, HeLa Cells

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3de745e2779247632c658448fd232552
https://pubmed.ncbi.nlm.nih.gov/19958286

المؤلفون: Banerjee, Sourav, Buhrlage, Sara J., Huang, Hai-Tsang, Deng, Xianming, Zhou, Wenjun, Wang, Jinhua, Traynor, Ryan, Prescott, Alan R., Alessi, Dario R., Gray, Nathanael S.

المصدر: Banerjee, Sourav, Sara J. Buhrlage, Hai-Tsang Huang, Xianming Deng, Wenjun Zhou, Jinhua Wang, Ryan Traynor, Alan R. Prescott, Dario R. Alessi, and Nathanael S. Gray. 2014. “Characterization of WZ4003 and HTH-01-015 as selective inhibitors of the LKB1-tumour-suppressor-activated NUAK kinases.” Biochemical Journal 457 (Pt 1): 215-225. doi:10.1042/BJ20131152. http://dx.doi.org/10.1042/BJ20131152.

مصطلحات موضوعية: AMP-activated protein kinase (AMPK), AMPK-related kinase 5 (ARK5), kinase inhibitor, kinase profiling, liver kinase B1 (LKB1), myosin phosphate-targeting subunit 1(MYPT1), sucrose-non-fermenting protein kinase/AMPKrelated protein kinase (SNARK), ACC, acetyl-CoA carboxylase, AMPK, AMP-activated protein kinase, BRSK, brain-specific kinase, DMEM, Dulbecco’s modified Eagle’s medium, HA, haemagglutinin, HEK, human embryonic kidney, LKB1, liver kinase B1, MARK, microtubule-affinity-regulating kinase, MEF, mouse embryonic fibroblast, MYPT1, myosin phosphate-targeting subunit 1, NF-κB, nuclear factor κB, PEI, polyethylenimine, PP1, protein phosphatase 1, SIK, salt-induced kinase

Relation: http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3969223/pdf/; Biochemical Journal

URL الوصول: http://nrs.harvard.edu/urn-3:HUL.InstRepos:12153015

المؤلفون: Ramamurthy S; Department of Neuroscience, Johns Hopkins University School of Medicine, 855 N Wolfe Street, Baltimore, MD 21205, USA; Center for Metabolism and Obesity Research, Johns Hopkins University School of Medicine, 855 N Wolfe Street, Baltimore, MD 21205, USA., Chang E; Department of Neuroscience, Johns Hopkins University School of Medicine, 855 N Wolfe Street, Baltimore, MD 21205, USA; Center for Metabolism and Obesity Research, Johns Hopkins University School of Medicine, 855 N Wolfe Street, Baltimore, MD 21205, USA., Cao Y; Department of Neuroscience, Johns Hopkins University School of Medicine, 855 N Wolfe Street, Baltimore, MD 21205, USA; Center for Metabolism and Obesity Research, Johns Hopkins University School of Medicine, 855 N Wolfe Street, Baltimore, MD 21205, USA., Zhu J; Department of Neuroscience, Johns Hopkins University School of Medicine, 855 N Wolfe Street, Baltimore, MD 21205, USA; Center for Metabolism and Obesity Research, Johns Hopkins University School of Medicine, 855 N Wolfe Street, Baltimore, MD 21205, USA., Ronnett GV; Department of Neuroscience, Johns Hopkins University School of Medicine, 855 N Wolfe Street, Baltimore, MD 21205, USA; Department of Neurology, Johns Hopkins University School of Medicine, 855 N Wolfe Street, Baltimore, MD 21205, USA; Department of Biological Chemistry, Johns Hopkins University School of Medicine, 855 N Wolfe Street, Baltimore, MD 21205, USA; Center for Metabolism and Obesity Research, Johns Hopkins University School of Medicine, 855 N Wolfe Street, Baltimore, MD 21205, USA; Daegu Gyeongbuk Institute of Science and Technology, Daegu, Republic of Korea. Electronic address: gronnett@jhmi.edu.

المصدر: Neuroscience [Neuroscience] 2014 Feb 14; Vol. 259, pp. 13-24. Date of Electronic Publication: 2013 Dec 01.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier Science Country of Publication: United States NLM ID: 7605074 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-7544 (Electronic) Linking ISSN: 03064522 NLM ISO Abbreviation: Neuroscience Subsets: MEDLINE

مواضيع طبية MeSH: AMP-Activated Protein Kinases/*metabolism , Dendrites/*physiology , Gene Expression Regulation, Developmental/*physiology , Hippocampus/*cytology , Neurites/*physiology , Neurons/*ultrastructure, AMP-Activated Protein Kinases/deficiency ; AMP-Activated Protein Kinases/genetics ; Age Factors ; Aminoimidazole Carboxamide/analogs & derivatives ; Aminoimidazole Carboxamide/pharmacology ; Animals ; Animals, Newborn ; Cells, Cultured ; Embryo, Mammalian ; Female ; Gene Expression Regulation, Developmental/drug effects ; Hypoglycemic Agents/pharmacology ; Male ; Mice ; Mice, Inbred C57BL ; Mice, Transgenic ; Neurons/physiology ; Rats ; Rats, Sprague-Dawley ; Ribonucleotides/pharmacology