المؤلفون: Sungwoo Kim, Josh Tycko, Michael C. Bassik, Wu T, Alexandro E. Trevino, Chuan He, William J. Greenleaf, Lacramioara Bintu, Georgi K. Marinov, Bagdatli St, Anshul Kundaje

مصطلحات موضوعية: Enzyme binding, chemistry.chemical_compound, chemistry, Cas9, Epigenome editing, CRISPR, Computational biology, Cleavage (embryo), Genome, DNA, Binding selectivity

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d201a2da891e424c8dbe75aed7c40e88
https://doi.org/10.1101/2021.04.16.440202

المؤلفون: De Rop FV; VIB Center for Brain and Disease Research, Leuven, Belgium.; Department of Human Genetics, KU Leuven, Leuven, Belgium., Hulselmans G; VIB Center for Brain and Disease Research, Leuven, Belgium.; Department of Human Genetics, KU Leuven, Leuven, Belgium., Flerin C; VIB Center for Brain and Disease Research, Leuven, Belgium.; Department of Human Genetics, KU Leuven, Leuven, Belgium., Soler-Vila P; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain., Rafels A; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Christiaens V; VIB Center for Brain and Disease Research, Leuven, Belgium.; Department of Human Genetics, KU Leuven, Leuven, Belgium., González-Blas CB; VIB Center for Brain and Disease Research, Leuven, Belgium.; Department of Human Genetics, KU Leuven, Leuven, Belgium., Marchese D; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Caratù G; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Poovathingal S; VIB Center for Brain and Disease Research, Leuven, Belgium., Rozenblatt-Rosen O; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Slyper M; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Luo W; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Muus C; Broad Institute of MIT and Harvard, Cambridge, MA, USA., Duarte F; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Shrestha R; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Bagdatli ST; Department of Genetics, Stanford University, Stanford, CA, USA., Corces MR; Gladstone Institute of Neurological Disease, San Francisco, CA, USA., Mamanova L; Wellcome Sanger Institute, Cambridge, UK., Knights A; Wellcome Sanger Institute, Cambridge, UK., Meyer KB; Wellcome Sanger Institute, Cambridge, UK., Mulqueen R; Department of Molecular and Medical Genetics, Oregon Health & Science University, Portland, OR, USA., Taherinasab A; Division of Hematology & Medical Oncology, Knight Cancer Institute, Oregon Health & Sciences University, Portland, OR, USA.; Division of Oncologic Sciences, Knight Cancer Institute, Oregon Health & Sciences University, Portland, OR, USA., Maschmeyer P; Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Berlin, Germany.; Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Institute for Medical Systems Biology (BIMSB), Berlin, Germany., Pezoldt J; Laboratory of Systems Biology and Genetics, Institute of Bioengineering, School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.; Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland., Lambert CLG; Laboratory of Systems Biology and Genetics, Institute of Bioengineering, School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.; Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland., Iglesias M; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain., Najle SR; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain., Dossani ZY; Vitalant Research Institute, San Francisco, CA, USA.; Department of Laboratory Medicine, University of California, San Francisco, CA, USA., Martelotto LG; Adelaide Centre for Epigenetics and the South Australian Immunogenomics Cancer Institute, Faculty of Health and Medical Sciences, The University of Adelaide, Adelaide, South Australia, Australia.; University of Melbourne Centre for Cancer Research, Victoria Comprehensive Cancer Centre, Melbourne, Victoria, Australia., Burkett Z; Digital Biology Group, Bio-Rad, Pleasanton, CA, USA., Lebofsky R; Digital Biology Group, Bio-Rad, Pleasanton, CA, USA., Martin-Subero JI; Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Departament de Fonaments Clínics, Facultat de Medicina, Universitat de Barcelona, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Madrid, Spain.; Institució Catalana de Recerca i Estudis Avançats (ICREA), Barcelona, Spain., Pillai S; Vitalant Research Institute, San Francisco, CA, USA.; Department of Laboratory Medicine, University of California, San Francisco, CA, USA., Sebé-Pedrós A; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain.; Universitat Pompeu Fabra (UPF), Barcelona, Spain.; ICREA, Barcelona, Spain., Deplancke B; Laboratory of Systems Biology and Genetics, Institute of Bioengineering, School of Life Sciences, École Polytechnique Fédérale de Lausanne (EPFL), Lausanne, Switzerland.; Swiss Institute of Bioinformatics (SIB), Lausanne, Switzerland., Teichmann SA; Wellcome Sanger Institute, Cambridge, UK.; Department of Physics/Cavendish Laboratory, University of Cambridge, Cambridge, UK., Ludwig LS; Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Berlin Institute of Health at Charité-Universitätsmedizin Berlin, Berlin, Germany.; Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), Berlin Institute for Medical Systems Biology (BIMSB), Berlin, Germany., Braun TP; Division of Hematology & Medical Oncology, Knight Cancer Institute, Oregon Health & Sciences University, Portland, OR, USA.; Division of Oncologic Sciences, Knight Cancer Institute, Oregon Health & Sciences University, Portland, OR, USA., Adey AC; Department of Molecular and Medical Genetics, Oregon Health & Science University, Portland, OR, USA., Greenleaf WJ; Department of Genetics, Stanford University, Stanford, CA, USA.; Chan Zuckerberg Biohub, San Francisco, CA, USA., Buenrostro JD; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA, USA.; Gene Regulation Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA., Regev A; Klarman Cell Observatory, Broad Institute of MIT and Harvard, Cambridge, MA, USA.; Koch Institute of Integrative Cancer Research, Cambridge, MA, USA.; Howard Hughes Medical Institute, Department of Biology, Massachusetts Institute of Technology (MIT), Cambridge, MA, USA., Aerts S; VIB Center for Brain and Disease Research, Leuven, Belgium. stein.aerts@kuleuven.be.; Department of Human Genetics, KU Leuven, Leuven, Belgium. stein.aerts@kuleuven.be., Heyn H; CNAG-CRG, Centre for Genomic Regulation (CRG), Barcelona Institute of Science and Technology (BIST), Barcelona, Spain. holger.heyn@cnag.crg.eu.; Universitat Pompeu Fabra (UPF), Barcelona, Spain. holger.heyn@cnag.crg.eu.

المصدر: Nature biotechnology [Nat Biotechnol] 2024 Jun; Vol. 42 (6), pp. 916-926. Date of Electronic Publication: 2023 Aug 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature America Publishing Country of Publication: United States NLM ID: 9604648 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1696 (Electronic) Linking ISSN: 10870156 NLM ISO Abbreviation: Nat Biotechnol Subsets: MEDLINE

مواضيع طبية MeSH: Single-Cell Analysis*/methods , Benchmarking* , Leukocytes, Mononuclear*, Humans ; Chromatin Immunoprecipitation Sequencing/methods ; Chromatin/genetics ; Transposases/genetics ; Sequence Analysis, DNA/methods ; High-Throughput Nucleotide Sequencing/methods

المؤلفون: Marinov GK; Department of Genetics, Stanford University, Stanford, CA, 94305, USA. GKM359@gmail.com., Bagdatli ST; Department of Genetics, Stanford University, Stanford, CA, 94305, USA., Wu T; Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, 60637, USA., He C; Department of Chemistry and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, 60637, USA.; Department of Biochemistry and Molecular Biology and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, 60637, USA.; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, 60637, USA., Kundaje A; Department of Genetics, Stanford University, Stanford, CA, 94305, USA.; Department of Computer Science, Stanford University, Stanford, CA, 94305, USA., Greenleaf WJ; Department of Genetics, Stanford University, Stanford, CA, 94305, USA.; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA, 94305, USA.; Department of Applied Physics, Stanford University, Stanford, CA, 94305, USA.; Chan Zuckerberg Biohub, San Francisco, CA, USA.

المصدر: Genome biology [Genome Biol] 2023 Nov 06; Vol. 24 (1), pp. 253. Date of Electronic Publication: 2023 Nov 06.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100960660 Publication Model: Electronic Cited Medium: Internet ISSN: 1474-760X (Electronic) Linking ISSN: 14747596 NLM ISO Abbreviation: Genome Biol Subsets: MEDLINE

مواضيع طبية MeSH: Haloferax volcanii*/genetics , Haloferax volcanii*/metabolism , Archaeal Proteins*/genetics, Chromatin ; Histones/genetics ; Nucleosomes ; Biological Evolution ; Eukaryota/genetics

المؤلفون: Marinov GK; Department of Genetics, School of Medicine, Stanford University, Stanford, CA, 94305, USA. GKM359@gmail.com., Kim SH; Cancer Biology Program, School of Medicine, Stanford University, Stanford, CA, 94305, USA., Bagdatli ST; Department of Genetics, School of Medicine, Stanford University, Stanford, CA, 94305, USA., Higashino SI; Department of Genetics, School of Medicine, Stanford University, Stanford, CA, 94305, USA., Trevino AE; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA, 94305, USA.; Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA., Tycko J; Department of Genetics, School of Medicine, Stanford University, Stanford, CA, 94305, USA., Wu T; Department of Chemistry, The University of Chicago, Chicago, IL, 60637, USA., Bintu L; Department of Bioengineering, Stanford University, Stanford, CA, 94305, USA., Bassik MC; Department of Genetics, School of Medicine, Stanford University, Stanford, CA, 94305, USA.; Chemistry, Engineering, and Medicine for Human Health (ChEM-H), Stanford University, Stanford, CA, 94305, USA., He C; Department of Chemistry, The University of Chicago, Chicago, IL, 60637, USA.; Department of Biochemistry and Molecular Biology and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL, 60637, USA.; Howard Hughes Medical Institute, The University of Chicago, Chicago, IL, 60637, USA., Kundaje A; Department of Genetics, School of Medicine, Stanford University, Stanford, CA, 94305, USA.; Department of Computer Science, Stanford University, Stanford, CA, 94305, USA., Greenleaf WJ; Department of Genetics, School of Medicine, Stanford University, Stanford, CA, 94305, USA. wjg@stanford.edu.; Department of Applied Physics, Stanford University, Stanford, CA, 94305, USA. wjg@stanford.edu.; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA, 94305, USA. wjg@stanford.edu.; Chan Zuckerberg Biohub, San Francisco, CA, USA. wjg@stanford.edu.

المصدر: Genome biology [Genome Biol] 2023 Apr 21; Vol. 24 (1), pp. 85. Date of Electronic Publication: 2023 Apr 21.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100960660 Publication Model: Electronic Cited Medium: Internet ISSN: 1474-760X (Electronic) Linking ISSN: 14747596 NLM ISO Abbreviation: Genome Biol Subsets: MEDLINE

مواضيع طبية MeSH: CRISPR-Cas Systems* , DNA, Single-Stranded*/genetics, Genome ; CRISPR-Associated Protein 9/genetics ; Epigenome ; Gene Editing/methods

المؤلفون: Kim SH; Cancer Biology Program, School of Medicine, Stanford University, Stanford, CA, USA. samhkim@stanford.edu.; Medical Scientist Training Program, Stanford University, Stanford, CA, USA. samhkim@stanford.edu., Marinov GK; Department of Genetics, Stanford University, Stanford, CA, USA., Bagdatli ST; Department of Genetics, Stanford University, Stanford, CA, USA., Higashino SI; Department of Genetics, Stanford University, Stanford, CA, USA., Shipony Z; Department of Genetics, Stanford University, Stanford, CA, USA., Kundaje A; Department of Genetics, Stanford University, Stanford, CA, USA.; Department of Computer Science, Stanford University, Stanford, CA, USA., Greenleaf WJ; Department of Genetics, Stanford University, Stanford, CA, USA.; Center for Personal Dynamic Regulomes, Stanford University, Stanford, California, USA.; Department of Applied Physics, Stanford University, Stanford, CA, USA.; Chan Zuckerberg Biohub, San Francisco, CA, USA.

المصدر: Methods in molecular biology (Clifton, N.J.) [Methods Mol Biol] 2023; Vol. 2611, pp. 187-230.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Humana Press Country of Publication: United States NLM ID: 9214969 Publication Model: Print Cited Medium: Internet ISSN: 1940-6029 (Electronic) Linking ISSN: 10643745 NLM ISO Abbreviation: Methods Mol Biol Subsets: MEDLINE

مواضيع طبية MeSH: Chromatin* , Transcriptome*, High-Throughput Nucleotide Sequencing/methods ; Sequence Analysis, DNA/methods ; Regulatory Sequences, Nucleic Acid ; Single-Cell Analysis/methods

المؤلفون: Granja JM; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA. jgranja.stanford@gmail.com.; Program in Biophysics, Stanford University, Stanford, CA, USA. jgranja.stanford@gmail.com.; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA, USA. jgranja.stanford@gmail.com., Corces MR; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA, USA.; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Gladstone Institute of Neurological Disease, Gladstone Institute of Data Science and Biotechnology, San Francisco, CA, USA.; Department of Neurology, University of California San Francisco, San Francisco, CA, USA., Pierce SE; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Program in Cancer Biology, Stanford University School of Medicine, Stanford, CA, USA., Bagdatli ST; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Choudhry H; Department of Biochemistry, Faculty of Science, Cancer and Mutagenesis Unit, King Fahd Center for Medical Research, King Abdulaziz University, Jeddah, Saudi Arabia., Chang HY; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA. howchang@stanford.edu.; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA, USA. howchang@stanford.edu.; Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA. howchang@stanford.edu., Greenleaf WJ; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA. wjg@stanford.edu.; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA, USA. wjg@stanford.edu.; Department of Applied Physics, Stanford University, Stanford, CA, USA. wjg@stanford.edu.; Chan Zuckerberg Biohub, San Francisco, CA, USA. wjg@stanford.edu.

المصدر: Nature genetics [Nat Genet] 2021 Jun; Vol. 53 (6), pp. 935.

نوع المنشور: Published Erratum

بيانات الدورية: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: PubMed not MEDLINE; MEDLINE

المؤلفون: Granja JM; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA. jgranja.stanford@gmail.com.; Program in Biophysics, Stanford University, Stanford, CA, USA. jgranja.stanford@gmail.com.; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA, USA. jgranja.stanford@gmail.com., Corces MR; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA, USA.; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Gladstone Institute of Neurological Disease, Gladstone Institute of Data Science and Biotechnology, San Francisco, CA, USA.; Department of Neurology, University of California San Francisco, San Francisco, CA, USA., Pierce SE; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Program in Cancer Biology, Stanford University School of Medicine, Stanford, CA, USA., Bagdatli ST; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Choudhry H; Department of Biochemistry, Faculty of Science, Cancer and Mutagenesis Unit, King Fahd Center for Medical Research, King Abdulaziz University, Jeddah, Saudi Arabia., Chang HY; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA. howchang@stanford.edu.; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA, USA. howchang@stanford.edu.; Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA. howchang@stanford.edu., Greenleaf WJ; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA. wjg@stanford.edu.; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA, USA. wjg@stanford.edu.; Department of Applied Physics, Stanford University, Stanford, CA, USA. wjg@stanford.edu.; Chan Zuckerberg Biohub, San Francisco, CA, USA. wjg@stanford.edu.

المصدر: Nature genetics [Nat Genet] 2021 Mar; Vol. 53 (3), pp. 403-411. Date of Electronic Publication: 2021 Feb 25.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE

مواضيع طبية MeSH: Chromatin*/genetics , Chromatin*/metabolism , Software*, Single-Cell Analysis/*methods, Animals ; Cluster Analysis ; Gene Expression Regulation ; Genome ; Humans ; Mice ; Sequence Analysis, RNA/methods ; Transcription Factors/genetics ; Transcription Factors/metabolism ; User-Computer Interface ; Web Browser

المؤلفون: Corces MR; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA, USA., Shcherbina A; Department of Biomedical Data Science, Stanford University School of Medicine, Stanford, CA, USA.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Kundu S; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Department of Computer Science, Stanford University, Stanford, CA, USA., Gloudemans MJ; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Biomedical Data Science, Stanford University School of Medicine, Stanford, CA, USA., Frésard L; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Granja JM; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA, USA.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Program in Biophysics, Stanford University, Stanford, CA, USA., Louie BH; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA, USA., Eulalio T; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Biomedical Data Science, Stanford University School of Medicine, Stanford, CA, USA., Shams S; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA, USA.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Bagdatli ST; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA, USA.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Mumbach MR; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA, USA.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Liu B; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Biology, Stanford University, Stanford, CA, USA.; Baidu Research, Sunnyvale, CA, USA., Montine KS; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA., Greenleaf WJ; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA, USA.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Department of Applied Physics, Stanford University, Stanford, CA, USA.; Chan Zuckerberg Biohub, San Francisco, CA, USA., Kundaje A; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA.; Department of Computer Science, Stanford University, Stanford, CA, USA., Montgomery SB; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA., Chang HY; Center for Personal Dynamic Regulomes, Stanford University, Stanford, CA, USA. howchang@stanford.edu.; Department of Genetics, Stanford University School of Medicine, Stanford, CA, USA. howchang@stanford.edu.; Program in Epithelial Biology, Stanford University, Stanford, CA, USA. howchang@stanford.edu.; Howard Hughes Medical Institute, Stanford University, Stanford, CA, USA. howchang@stanford.edu., Montine TJ; Department of Pathology, Stanford University School of Medicine, Stanford, CA, USA. tmontine@stanford.edu.

المصدر: Nature genetics [Nat Genet] 2020 Nov; Vol. 52 (11), pp. 1158-1168. Date of Electronic Publication: 2020 Oct 26.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE

مواضيع طبية MeSH: Alzheimer Disease/*genetics , Brain/*anatomy & histology , Neurons/*physiology , Parkinson Disease/*genetics, Adult ; Atlases as Topic ; Biological Variation, Population ; Chromatin Assembly and Disassembly ; Cohort Studies ; Enhancer Elements, Genetic ; Epigenomics ; Genetic Heterogeneity ; Genetic Predisposition to Disease ; Genome-Wide Association Study ; Haplotypes ; Humans ; Machine Learning ; Polymorphism, Single Nucleotide ; Promoter Regions, Genetic ; tau Proteins/genetics