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1
المؤلفون: Jeffrey J Barlow, Lynn Scarlett, Keith Hopkinson Gibson, Susan Ashton, Walter Grundy, Lianne Henthorn, Laura Richards, Brenda Curry, Mark P Healy, Barker Andrew John, J. R. Woodburn, Godfrey Andrew Aydon
المصدر: Bioorganic & Medicinal Chemistry Letters. 11:1911-1914
مصطلحات موضوعية: Clinical Biochemistry, Administration, Oral, Pharmaceutical Science, Antineoplastic Agents, Sensitivity and Specificity, Biochemistry, KB Cells, Gefitinib, Growth factor receptor, Epidermal growth factor, Drug Discovery, Tumor Cells, Cultured, medicine, Humans, Growth factor receptor inhibitor, Molecular Biology, biology, Chemistry, Organic Chemistry, Cancer, medicine.disease, ErbB Receptors, Enzyme inhibitor, Carcinoma, Squamous Cell, Quinazolines, biology.protein, Cancer research, Molecular Medicine, Signal transduction, Tyrosine kinase, medicine.drug
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2
المؤلفون: L. Scarlett, Walter Grundy, Barker Andrew John, Keith Hopkinson Gibson, J. R. Woodburn, Susan Ashton, Godfrey Andrew Aydon, D. S. Brown, Brenda Curry
المصدر: Bioorganic & Medicinal Chemistry Letters. 7:2723-2728
مصطلحات موضوعية: chemistry.chemical_classification, biology, Chemistry, Organic Chemistry, Clinical Biochemistry, Pharmaceutical Science, Pharmacology, Biochemistry, In vitro, Enzyme, Epidermoid carcinoma, Enzyme inhibitor, In vivo, Epidermal growth factor, Drug Discovery, biology.protein, Molecular Medicine, Signal transduction, Molecular Biology, Tyrosine kinase
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3
المؤلفون: Godfrey Andrew Aydon, Susan Ashton, J. R. Woodburn, Walter Grundy, L. Scarlett, Barker Andrew John, Brenda Curry, Keith Hopkinson Gibson, D. S. Brown
المصدر: ChemInform. 29
مصطلحات موضوعية: Antitumor activity, Biochemistry, Chemistry, General Medicine, Pharmacology, Epidermal growth factor receptor tyrosine kinase
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4
المؤلفون: Kin Yip Tam, David Alan Rudge, Julie A. Tucker, Louise Moss, Barker Andrew John, Clifford David Jones, Peter B. Simpson, Alexandra McGregor, David M. Andrews, Michael A. Walker, Kevin Blades, Catherine Geh, Swain Michael Lingard, S J East, Keith M. Johnson, Heather M. McFarland, Mark A. Graham, Sarah A. Loddick, Paula Daunt
المصدر: Bioorganicmedicinal chemistry letters. 18(24)
مصطلحات موضوعية: ERG1 Potassium Channel, Pyrimidine, Clinical Biochemistry, hERG, Molecular Conformation, Pharmaceutical Science, Crystallography, X-Ray, Biochemistry, chemistry.chemical_compound, Cyclin-dependent kinase, Cell Line, Tumor, Drug Discovery, Imidazole, Humans, Protein Isoforms, Infusions, Intravenous, Molecular Biology, Protein Kinase Inhibitors, Cyclin-Dependent Kinase Inhibitor Proteins, biology, Chemistry, Chemistry, Physical, Organic Chemistry, Imidazoles, Biological activity, Amides, Ether-A-Go-Go Potassium Channels, Pyrimidines, Models, Chemical, Enzyme inhibitor, Drug Design, Lipophilicity, biology.protein, Molecular Medicine, CDK inhibitor, Neoplasm Transplantation
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5
المؤلفون: Kate Byth, Barker Andrew John, David M. Andrews, Marie Willaing Johannsen, M. Raymond V. Finlay, Clive Green, Hazel M. Weir, Catherine Geh, Kevin Blades, Clifford David Jones, Michael A. Walker
المصدر: Bioorganicmedicinal chemistry letters. 18(24)
مصطلحات موضوعية: Male, Pyrimidine, medicine.drug_class, Clinical Biochemistry, hERG, Pharmaceutical Science, Administration, Oral, Mice, Nude, Carboxamide, Biochemistry, chemistry.chemical_compound, Inhibitory Concentration 50, Mice, In vivo, Cyclin-dependent kinase, Cell Line, Tumor, Drug Discovery, medicine, Animals, Humans, Rats, Wistar, Molecular Biology, Cyclin-Dependent Kinase Inhibitor Proteins, biology, Organic Chemistry, Cyclin-dependent kinase 2, Imidazoles, Rats, Pyrimidines, chemistry, Enzyme inhibitor, Lipophilicity, biology.protein, Molecular Medicine, Female, Drug Screening Assays, Antitumor
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6
المؤلفون: David William AstraZeneca R D Alderley Heaton, Hazel M. Weir, Julie A. Tucker, Eric Fisher, Galith Karoutchi, Sarah A. Loddick, Mark A. Graham, Michael Dennis, Clive Green, Barker Andrew John, David M. Andrews, Andrew D. Roberts, M. Raymond V. Finlay, Rémy Morgentin, David G. Acton
المصدر: Bioorganicmedicinal chemistry letters. 18(15)
مصطلحات موضوعية: Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Mice, Nude, Antineoplastic Agents, Biochemistry, Chemical synthesis, Piperazines, Mice, Structure-Activity Relationship, Cyclin-dependent kinase, Drug Discovery, Structure–activity relationship, Transferase, Animals, Combinatorial Chemistry Techniques, Binding site, Enzyme Inhibitors, Molecular Biology, chemistry.chemical_classification, Aspartic Acid, Binding Sites, biology, Molecular Structure, Chemistry, Kinase, Organic Chemistry, Cyclin-dependent kinase 2, Cyclin-Dependent Kinase 2, Imidazoles, Xenograft Model Antitumor Assays, Cyclin-Dependent Kinases, Enzyme, Drug Design, biology.protein, Molecular Medicine, Drug Screening Assays, Antitumor
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7
المؤلفون: Barker Andrew John, Keith Hopkinson Gibson, A. E. Wakeling, L. Scarlett, Susan Ashton, L. R. Henthorn, Brenda Curry, J. R. Woodburn
المصدر: Journal of Immunotherapy. 20:408
مصطلحات موضوعية: Pharmacology, Cancer Research, TGF alpha, biology, medicine.drug_class, Chemistry, Immunology, Receptor tyrosine kinase, Tyrosine-kinase inhibitor, Epidermal growth factor, biology.protein, medicine, Cancer research, Immunology and Allergy, Growth factor receptor inhibitor, Tyrosine kinase, Platelet-derived growth factor receptor, Proto-oncogene tyrosine-protein kinase Src
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::aaf62e8dcca61cf4a540c8640c36e7bd
https://doi.org/10.1097/00002371-199709000-00044