المؤلفون: Leslie, J, Macia, MG, Luli, S, Worrell, JC, Reilly, WJ, Paish, HL, Knox, A, Barksby, BS, Gee, LM, Zaki, MYW, Collins, AL, Burgoyne, RA, Cameron, R, Bragg, C, Xu, X, Chung, GW, Brown, CDA, Blanchard, AD, Nanthakumar, CB, Karsdal, M, Robinson, SM, Manas, DM, Sen, G, French, J, White, SA, Murphy, S, Trost, M, Zakrzewski, JL, Klein, U, Schwabe, RF, Mederacke, I, Nixon, C, Bird, T, Teuwen, L-A, Schoonjans, L, Carmeliet, P, Mann, J, Fisher, AJ, Sheerin, NS, Borthwick, LA, Mann, DA, Oakley, F

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=core_ac_uk__::ce12613661775651b9ca842039c6f191

المؤلفون: Wilkinson AL; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK., John AE; Margaret Turner Warwick Centre for Fibrosing Lung Disease, National Heart and Lung Institute, Imperial College London, Guy Scadding Building, Cale Street, London, UK., Barrett JW; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Gower E; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Morrison VS; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Man Y; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Pun KT; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Roper JA; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Luckett JC; Nottingham Respiratory Research Unit, University of Nottingham, Nottingham, UK., Borthwick LA; Fibrosis Research Group, Newcastle University Biosciences Institute, Newcastle University Translational and Clinical Research Institute, Newcastle Upon Tyne, UK., Barksby BS; Fibrosis Research Group, Newcastle University Biosciences Institute, Newcastle University Translational and Clinical Research Institute, Newcastle Upon Tyne, UK., Burgoyne RA; Fibrosis Research Group, Newcastle University Biosciences Institute, Newcastle University Translational and Clinical Research Institute, Newcastle Upon Tyne, UK., Barnes R; Fibrosis Research Group, Newcastle University Biosciences Institute, Newcastle University Translational and Clinical Research Institute, Newcastle Upon Tyne, UK., Fisher AJ; Fibrosis Research Group, Newcastle University Biosciences Institute, Newcastle University Translational and Clinical Research Institute, Newcastle Upon Tyne, UK; Institute of Transplantation, Freeman Hospital, Newcastle Upon Tyne Hospitals NHS, Foundation Trust, Newcastle Upon Tyne, UK., Procopiou PA; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Hatley RJD; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Barrett TN; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Marshall RP; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Macdonald SJF; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Jenkins RG; Margaret Turner Warwick Centre for Fibrosing Lung Disease, National Heart and Lung Institute, Imperial College London, Guy Scadding Building, Cale Street, London, UK., Slack RJ; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK. Electronic address: RJSlack@galecto.com.

المصدر: European journal of pharmacology [Eur J Pharmacol] 2021 Dec 15; Vol. 913, pp. 174618. Date of Electronic Publication: 2021 Nov 08.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Science Country of Publication: Netherlands NLM ID: 1254354 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0712 (Electronic) Linking ISSN: 00142999 NLM ISO Abbreviation: Eur J Pharmacol Subsets: MEDLINE

مواضيع طبية MeSH: Antifibrotic Agents/*pharmacology , Integrins/*antagonists & inhibitors , Pulmonary Fibrosis/*drug therapy, Administration, Oral ; Animals ; Antifibrotic Agents/chemistry ; Antifibrotic Agents/therapeutic use ; Antigens, Neoplasm/chemistry ; Antigens, Neoplasm/metabolism ; Biological Availability ; Bleomycin/administration & dosage ; Bleomycin/toxicity ; Cells, Cultured ; Disease Models, Animal ; Epithelial Cells/drug effects ; Epithelial Cells/pathology ; Humans ; Integrins/chemistry ; Integrins/metabolism ; Lung/drug effects ; Lung/pathology ; Lysosomes/metabolism ; Male ; Mice ; Oligopeptides/chemistry ; Primary Cell Culture ; Proteolysis/drug effects ; Pulmonary Fibrosis/chemically induced ; Pulmonary Fibrosis/pathology ; Transforming Growth Factor beta/metabolism

المؤلفون: Leslie J; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK. jack.leslie@newcastle.ac.uk., Macia MG; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Luli S; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Worrell JC; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Reilly WJ; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Paish HL; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Knox A; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Barksby BS; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Gee LM; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Zaki MYW; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Biochemistry Department, Faculty of Pharmacy, Minia University, Minia, Egypt., Collins AL; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Burgoyne RA; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Cameron R; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Bragg C; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Xu X; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Chung GW; Newcells Biotech, The Biosphere, Newcastle Helix, Newcastle upon Tyne, UK., Brown CDA; Newcells Biotech, The Biosphere, Newcastle Helix, Newcastle upon Tyne, UK., Blanchard AD; Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, UK., Nanthakumar CB; Fibrosis Discovery Performance Unit, Respiratory Therapy Area, Medicines Research Centre, GlaxoSmithKline R&D, Stevenage, UK., Karsdal M; Nordic Bioscience A/S, Biomarkers & Research, Herlev, Denmark., Robinson SM; Department of Hepatobiliary Surgery, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Manas DM; Department of Hepatobiliary Surgery, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Sen G; Department of Hepatobiliary Surgery, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., French J; Department of Hepatobiliary Surgery, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., White SA; Department of Hepatobiliary Surgery, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Murphy S; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Trost M; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Zakrzewski JL; Center for Discovery and Innovation and John Theurer Cancer Center, Hackensack University Medical Center, Hackensack, NJ, USA., Klein U; Division of Haematology & Immunology, Leeds Institute of Medical Research at St. James's, University of Leeds, Leeds, UK., Schwabe RF; Department of Medicine, Columbia University, New York, NY, USA., Mederacke I; Department of Gastroenterology, Hepatology and Endocrinology, Hannover Medical School, Hannover, Germany., Nixon C; Cancer Research UK Beatson Institute, Garscube Estate, Glasgow, UK., Bird T; Cancer Research UK Beatson Institute, Garscube Estate, Glasgow, UK.; Institute of Cancer Sciences, University of Glasgow, Garscube Estate, Glasgow, UK.; MRC Centre for Inflammation Research, The Queen's Medical Research Institute, University of Edinburgh, Edinburgh, UK., Teuwen LA; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, Leuven, Belgium., Schoonjans L; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, Leuven, Belgium., Carmeliet P; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology, VIB, Leuven, Belgium.; Laboratory of Angiogenesis and Vascular Metabolism, Center for Cancer Biology, Department of Oncology and Leuven Cancer Institute (LKI), KU Leuven, Leuven, Belgium., Mann J; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Fibrofind, Medical School, Newcastle University, Newcastle upon Tyne, UK., Fisher AJ; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Institute of Transplantation, The Freeman Hospital, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, UK., Sheerin NS; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK., Borthwick LA; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Fibrofind, Medical School, Newcastle University, Newcastle upon Tyne, UK., Mann DA; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK.; Fibrofind, Medical School, Newcastle University, Newcastle upon Tyne, UK., Oakley F; Newcastle Fibrosis Research Group, Biosciences Institute, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, UK. fiona.oakley@newcastle.ac.uk.; Fibrofind, Medical School, Newcastle University, Newcastle upon Tyne, UK. fiona.oakley@newcastle.ac.uk.

المصدر: Nature metabolism [Nat Metab] 2020 Nov; Vol. 2 (11), pp. 1350-1367. Date of Electronic Publication: 2020 Nov 09.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Springer Nature Country of Publication: Germany NLM ID: 101736592 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2522-5812 (Electronic) Linking ISSN: 25225812 NLM ISO Abbreviation: Nat Metab Subsets: MEDLINE

مواضيع طبية MeSH: Epithelium/*pathology , Liver Cirrhosis/*genetics , Liver Cirrhosis/*pathology , Macrophages/*pathology , Proto-Oncogene Proteins c-rel/*genetics, Animals ; Cell Polarity/genetics ; Gene Targeting ; Hepatocytes/pathology ; Hydroxyproline/metabolism ; Liver Cirrhosis/prevention & control ; Liver Regeneration/genetics ; Mice ; Mice, Inbred C57BL ; Mice, Knockout ; Mitosis/genetics ; Paracrine Communication/genetics ; Phosphofructokinase-2/genetics ; Proto-Oncogene Proteins c-rel/antagonists & inhibitors ; Proto-Oncogene Proteins c-rel/metabolism

المؤلفون: John AE; Respiratory Medicine NIHR Biomedical Research Centre, University of Nottingham, Nottingham, UK., Graves RH; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Pun KT; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Vitulli G; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Forty EJ; Centre for Inflammation and Tissue Repair, University College London, London, UK., Mercer PF; Centre for Inflammation and Tissue Repair, University College London, London, UK., Morrell JL; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Barrett JW; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Rogers RF; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Hafeji M; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Bibby LI; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Gower E; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Morrison VS; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Man Y; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Roper JA; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Luckett JC; Radiological Sciences, University of Nottingham, Nottingham, UK., Borthwick LA; Fibrosis Research Group, Newcastle University Biosciences Institute and Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK., Barksby BS; Fibrosis Research Group, Newcastle University Biosciences Institute and Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK., Burgoyne RA; Fibrosis Research Group, Newcastle University Biosciences Institute and Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK., Barnes R; Fibrosis Research Group, Newcastle University Biosciences Institute and Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK., Le J; Drug Design and Selection - Molecular Design, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Flint DJ; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK., Pyne S; Strathclyde Institute of Pharmacy and Biomedical Sciences, University of Strathclyde, Glasgow, UK., Habgood A; Respiratory Medicine NIHR Biomedical Research Centre, University of Nottingham, Nottingham, UK., Organ LA; Respiratory Medicine NIHR Biomedical Research Centre, University of Nottingham, Nottingham, UK., Joseph C; Respiratory Medicine NIHR Biomedical Research Centre, University of Nottingham, Nottingham, UK., Edwards-Pritchard RC; Respiratory Medicine NIHR Biomedical Research Centre, University of Nottingham, Nottingham, UK., Maher TM; NIHR Respiratory Clinical Research Facility, Royal Brompton Hospital, London, UK.; Fibrosis Research Group, National Heart and Lung Institute, Imperial College, London, UK., Fisher AJ; Fibrosis Research Group, Newcastle University Biosciences Institute and Newcastle University Translational and Clinical Research Institute, Newcastle upon Tyne, UK.; Institute of Transplantation, Freeman Hospital, Newcastle Upon Tyne Hospitals NHS, Foundation Trust, Newcastle upon Tyne, UK., Gudmann NS; Nordic Bioscience A/S, Biomarkers and Research, Herlev Hovedgade 205-207, Herlev, Denmark., Leeming DJ; Nordic Bioscience A/S, Biomarkers and Research, Herlev Hovedgade 205-207, Herlev, Denmark., Chambers RC; Centre for Inflammation and Tissue Repair, University College London, London, UK., Lukey PT; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Marshall RP; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Macdonald SJF; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK., Jenkins RG; Respiratory Medicine NIHR Biomedical Research Centre, University of Nottingham, Nottingham, UK. gisli.jenkins@nottingham.ac.uk., Slack RJ; Fibrosis DPU, Respiratory TAU, GlaxoSmithKline, Stevenage, Hertfordshire, UK.

المصدر: Nature communications [Nat Commun] 2020 Sep 16; Vol. 11 (1), pp. 4659. Date of Electronic Publication: 2020 Sep 16.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Butyrates/*pharmacology , Idiopathic Pulmonary Fibrosis/*drug therapy , Integrins/*antagonists & inhibitors , Naphthyridines/*pharmacology , Pyrazoles/*pharmacology , Pyrrolidines/*pharmacology, Administration, Inhalation ; Animals ; Antigens, Neoplasm/metabolism ; Bleomycin/toxicity ; Butyrates/administration & dosage ; Butyrates/metabolism ; Butyrates/pharmacokinetics ; Collagen/metabolism ; Disease Models, Animal ; Epithelial Cells/drug effects ; Humans ; Idiopathic Pulmonary Fibrosis/chemically induced ; Idiopathic Pulmonary Fibrosis/pathology ; Integrins/metabolism ; Male ; Mice, Inbred C57BL ; Molecular Docking Simulation ; Naphthyridines/administration & dosage ; Naphthyridines/metabolism ; Naphthyridines/pharmacokinetics ; Pyrazoles/administration & dosage ; Pyrazoles/metabolism ; Pyrazoles/pharmacokinetics ; Pyrrolidines/administration & dosage ; Pyrrolidines/metabolism ; Pyrrolidines/pharmacokinetics ; Small Molecule Libraries/chemistry ; Small Molecule Libraries/pharmacology ; Tomography, Emission-Computed, Single-Photon ; Transforming Growth Factor beta/metabolism ; Translational Research, Biomedical

المؤلفون: Marsh EK; Department of Infection, Immunity and Cardiovascular Disease, Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, United Kingdom.; Human Sciences Research Centre, College of Life and Natural Sciences, University of Derby, Derby, United Kingdom., Prestwich EC; Department of Infection, Immunity and Cardiovascular Disease, Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, United Kingdom., Williams L; Department of Infection, Immunity and Cardiovascular Disease, Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, United Kingdom., Hart AR; Department of Infection, Immunity and Cardiovascular Disease, Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, United Kingdom., Muir CF; Department of Infection, Immunity and Cardiovascular Disease, Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, United Kingdom., Parker LC; Department of Infection, Immunity and Cardiovascular Disease, Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, United Kingdom., Jonker MR; Department of Pathology and Medical Biology, University of Groningen, University Medical Centre Groningen, Groningen, Netherlands., Heijink IH; Department of Pathology and Medical Biology, University of Groningen, University Medical Centre Groningen, Groningen, Netherlands., Timens W; Department of Pathology and Medical Biology, University of Groningen, University Medical Centre Groningen, Groningen, Netherlands., Fife M; Manchester Collaborative Centre for Inflammation Research, Core Technology Facility, University of Manchester, Manchester, United Kingdom., Hussell T; Manchester Collaborative Centre for Inflammation Research, Core Technology Facility, University of Manchester, Manchester, United Kingdom., Hershenson MB; Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, MI, United States., Bentley JK; Department of Pediatrics and Communicable Diseases, University of Michigan Medical School, Ann Arbor, MI, United States., Sun SC; Department of Immunology, University of Texas MD Anderson Cancer Center, Houston, TX, United States., Barksby BS; Newcastle Fibrosis Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom., Borthwick LA; Newcastle Fibrosis Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle upon Tyne, United Kingdom., Stewart JP; Department of Infection Biology, University of Liverpool, Liverpool, United Kingdom., Sabroe I; Department of Infection, Immunity and Cardiovascular Disease, Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, United Kingdom., Dockrell DH; Department of Infection, Immunity and Cardiovascular Disease, Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, United Kingdom.; MRC/UoE Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, United Kingdom., Marriott HM; Department of Infection, Immunity and Cardiovascular Disease, Faculty of Medicine, Dentistry and Health, University of Sheffield, Sheffield, United Kingdom.

المصدر: Frontiers in cellular and infection microbiology [Front Cell Infect Microbiol] 2020 Aug 31; Vol. 10, pp. 456. Date of Electronic Publication: 2020 Aug 31 (Print Publication: 2020).

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Frontiers Media SA Country of Publication: Switzerland NLM ID: 101585359 Publication Model: eCollection Cited Medium: Internet ISSN: 2235-2988 (Electronic) Linking ISSN: 22352988 NLM ISO Abbreviation: Front Cell Infect Microbiol Subsets: MEDLINE

مواضيع طبية MeSH: Picornaviridae Infections* , Pulmonary Disease, Chronic Obstructive* , Virus Diseases*, Animals ; Humans ; Mice ; Mice, Inbred C57BL ; Nuclear Proteins ; Rhinovirus ; Ubiquitin-Protein Ligases/genetics

المؤلفون: Leslie J; Newcastle Fibrosis Research Group and., Millar BJ; Newcastle Fibrosis Research Group and., Del Carpio Pons A; Newcastle Fibrosis Research Group and., Burgoyne RA; Newcastle Fibrosis Research Group and., Frost JD; Newcastle Fibrosis Research Group and., Barksby BS; Newcastle Fibrosis Research Group and., Luli S; Newcastle Fibrosis Research Group and., Scott J; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom., Simpson AJ; Translational and Clinical Research Institute, Newcastle University, Newcastle upon Tyne, United Kingdom.; Interstitial Lung Disease Clinic, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom., Gauldie J; Firestone Institute for Respiratory Health, Saint Joseph's Healthcare and Department of Pathology and Molecular Medicine, McMaster University Hamilton, Hamilton, Ontario, Canada., Murray LA; MedImmune Ltd., Cambridge, United Kingdom., Finch DK; MedImmune Ltd., Cambridge, United Kingdom., Carruthers AM; MedImmune Ltd., Cambridge, United Kingdom., Ferguson J; MedImmune Ltd., Cambridge, United Kingdom., Sleeman MA; MedImmune Ltd., Cambridge, United Kingdom., Rider D; MedImmune Ltd., Cambridge, United Kingdom., Howarth R; Newcastle Fibrosis Research Group and., Fox C; Newcastle Fibrosis Research Group and., Oakley F; Newcastle Fibrosis Research Group and., Fisher AJ; Newcastle Fibrosis Research Group and.; Institute of Transplantation, Freeman Hospital, Newcastle upon Tyne, United Kingdom., Mann DA; Newcastle Fibrosis Research Group and., Borthwick LA; Newcastle Fibrosis Research Group and.

المصدر: JCI insight [JCI Insight] 2020 Feb 27; Vol. 5 (4). Date of Electronic Publication: 2020 Feb 27.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 101676073 Publication Model: Electronic Cited Medium: Internet ISSN: 2379-3708 (Electronic) Linking ISSN: 23793708 NLM ISO Abbreviation: JCI Insight Subsets: MEDLINE

مواضيع طبية MeSH: Neutrophil Infiltration/*physiology , Pulmonary Fibrosis/*physiopathology , Receptors, Formyl Peptide/*physiology, Animals ; Bleomycin/toxicity ; Humans ; Ligands ; Mice, Inbred C57BL ; Mice, Knockout ; Pulmonary Fibrosis/chemically induced ; Pulmonary Fibrosis/pathology ; Receptors, Formyl Peptide/genetics ; Receptors, Formyl Peptide/metabolism

المؤلفون: Paish HL; Newcastle Fibrosis Research Group, Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Reed LH; Newcastle Fibrosis Research Group, Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Brown H; Newcastle Fibrosis Research Group, Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Bryan MC; Newcastle Fibrosis Research Group, Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Govaere O; Liver Research Group, Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Leslie J; Newcastle Fibrosis Research Group, Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Barksby BS; Newcastle Fibrosis Research Group, Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Garcia Macia M; Newcastle Fibrosis Research Group, Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Watson A; Newcastle Fibrosis Research Group, Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Xu X; Newcastle Fibrosis Research Group, Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Zaki MYW; Newcastle Fibrosis Research Group, Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Greaves L; Newcastle University LLHW Centre for Ageing and Vitality, Newcastle University, Newcastle upon Tyne, United Kingdom.; Wellcome Centre for Mitochondrial Research, Institute of Neuroscience, Newcastle University, Newcastle upon Tyne, United Kingdom., Whitehall J; Newcastle University LLHW Centre for Ageing and Vitality, Newcastle University, Newcastle upon Tyne, United Kingdom., French J; Department of Hepatobiliary Surgery, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom., White SA; Department of Hepatobiliary Surgery, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom., Manas DM; Department of Hepatobiliary Surgery, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom., Robinson SM; Department of Hepatobiliary Surgery, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom., Spoletini G; Department of Hepatobiliary Surgery, Newcastle upon Tyne Hospitals NHS Foundation Trust, Newcastle upon Tyne, United Kingdom., Griffiths C; Newcastle Fibrosis Research Group, Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Mann DA; Newcastle Fibrosis Research Group, Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Borthwick LA; Newcastle Fibrosis Research Group, Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Drinnan MJ; Newcastle Fibrosis Research Group, Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Mann J; Newcastle Fibrosis Research Group, Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom., Oakley F; Newcastle Fibrosis Research Group, Institute of Cellular Medicine, Faculty of Medical Sciences, Newcastle University, Newcastle upon Tyne, United Kingdom.

المصدر: Hepatology (Baltimore, Md.) [Hepatology] 2019 Oct; Vol. 70 (4), pp. 1377-1391. Date of Electronic Publication: 2019 May 28.

نوع المنشور: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wolters Kluwer Health, Inc Country of Publication: United States NLM ID: 8302946 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-3350 (Electronic) Linking ISSN: 02709139 NLM ISO Abbreviation: Hepatology Subsets: MEDLINE

مواضيع طبية MeSH: Bioreactors* , Gene Expression Regulation*, Liver Cirrhosis/*genetics , Liver Cirrhosis/*pathology , Tissue Culture Techniques/*methods, Animals ; Biopsy, Needle ; Coculture Techniques/methods ; Disease Models, Animal ; Humans ; Immunohistochemistry ; Male ; Random Allocation ; Rats ; Rats, Sprague-Dawley ; Sensitivity and Specificity ; Time Factors