المؤلفون: Chen, RY, Via, LE, Dodd, LE, Walzl, G, Malherbe, ST, Loxton, AG, Dawson, R, Wilkinson, RJ, Thienemann, F, Tameris, M, Hatherill, M, Diacon, AH, Liu, X, Xing, J, Jin, X, Ma, Z, Pan, S, Zhang, G, Gao, Q, Jiang, Q, Zhu, H, Liang, L, Duan, H, Song, T, Alland, D, Tartakovsky, M, Rosenthal, A, Whalen, C, Duvenhage, M, Cai, Y, Goldfeder, LC, Arora, K, Smith, B, Winter, J, Barry Iii, CE, Predict TB Study Group

المساهمون: European and Developing Countries Clinical Trials Partnership

مصطلحات موضوعية: Model organisms, Human Biology & Physiology, drug sensitive, treatment shortening, PET/CT, FOS: Clinical medicine, Immunology, biomarkers, GeneXpert, Infectious Disease, MERM, pulmonary tuberculosis, cycle threshold

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bf92b84578644929cf424244724f99ac

المؤلفون: Chengalroyen MD; SAMRC/NHLS/UCT Molecular Mycobacteriology Research Unit, DST/NRF Centre of Excellence for Biomedical TB Research, Institute of Infectious Disease and Molecular Medicine and Department of Pathology, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory 7925, South Africa., Mason MK; SAMRC/NHLS/UCT Molecular Mycobacteriology Research Unit, DST/NRF Centre of Excellence for Biomedical TB Research, Institute of Infectious Disease and Molecular Medicine and Department of Pathology, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory 7925, South Africa., Borsellini A; Cell and Chemical Biology, Leiden University Medical Center, Einthovenweg 20, 2333 ZC Leiden, The Netherlands., Tassoni R; Cell and Chemical Biology, Leiden University Medical Center, Einthovenweg 20, 2333 ZC Leiden, The Netherlands., Abrahams GL; SAMRC/NHLS/UCT Molecular Mycobacteriology Research Unit, DST/NRF Centre of Excellence for Biomedical TB Research, Institute of Infectious Disease and Molecular Medicine and Department of Pathology, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory 7925, South Africa.; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Disease, National Institutes of Health, 9000 Rockville Pike, Bethesda, Maryland 20892, United States., Lynch S; SAMRC/NHLS/UCT Molecular Mycobacteriology Research Unit, DST/NRF Centre of Excellence for Biomedical TB Research, Institute of Infectious Disease and Molecular Medicine and Department of Pathology, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory 7925, South Africa., Ahn YM; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Disease, National Institutes of Health, 9000 Rockville Pike, Bethesda, Maryland 20892, United States., Ambler J; Wellcome Centre for Infectious Diseases Research in Africa, University of Cape Town, Anzio Road, Observatory 7925, South Africa., Young K; Infectious Disease, Merck & Co. Inc., West Point, Pennsylvania 19446, United States., Crowley BM; Discovery Chemistry, Merck & Co. Inc., West Point, Pennsylvania 19446, United States., Olsen DB; Infectious Disease, Merck & Co. Inc., West Point, Pennsylvania 19446, United States., Warner DF; SAMRC/NHLS/UCT Molecular Mycobacteriology Research Unit, DST/NRF Centre of Excellence for Biomedical TB Research, Institute of Infectious Disease and Molecular Medicine and Department of Pathology, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory 7925, South Africa., Barry Iii CE; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Disease, National Institutes of Health, 9000 Rockville Pike, Bethesda, Maryland 20892, United States., Boshoff HIM; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Disease, National Institutes of Health, 9000 Rockville Pike, Bethesda, Maryland 20892, United States., Lamers MH; Cell and Chemical Biology, Leiden University Medical Center, Einthovenweg 20, 2333 ZC Leiden, The Netherlands., Mizrahi V; SAMRC/NHLS/UCT Molecular Mycobacteriology Research Unit, DST/NRF Centre of Excellence for Biomedical TB Research, Institute of Infectious Disease and Molecular Medicine and Department of Pathology, Faculty of Health Sciences, University of Cape Town, Anzio Road, Observatory 7925, South Africa.

المصدر: ACS infectious diseases [ACS Infect Dis] 2022 Mar 11; Vol. 8 (3), pp. 612-625. Date of Electronic Publication: 2022 Feb 10.

نوع المنشور: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: ACS Publications Country of Publication: United States NLM ID: 101654580 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2373-8227 (Electronic) Linking ISSN: 23738227 NLM ISO Abbreviation: ACS Infect Dis Subsets: MEDLINE

مواضيع طبية MeSH: Mycobacterium tuberculosis*/genetics , Tuberculosis*/drug therapy , Tuberculosis*/microbiology, Anti-Bacterial Agents/pharmacology ; Cryoelectron Microscopy ; DNA-Directed DNA Polymerase ; Humans

المؤلفون: Sakai S; T Lymphocyte Biology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA., Lora NE; T Lymphocyte Biology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA., Kauffman KD; T Lymphocyte Biology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA., Dorosky DE; T Lymphocyte Biology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA., Oh S; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA., Namasivayam S; Immunobiology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA., Gomez F; Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Fleegle JD; Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Arlehamn CSL; Center for Infectious Disease, La Jolla Institute for Immunology, La Jolla, CA, USA., Sette A; Center for Infectious Disease, La Jolla Institute for Immunology, La Jolla, CA, USA.; Department of Medicine, University of California San Diego, La Jolla, CA, USA., Sher A; Immunobiology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA., Freeman GJ; Department of Medical Oncology, Dana-Farber Cancer Institute, Harvard Medical School, Boston, MA, USA., Via LE; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA.; Division of Intramural Research, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.; Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa., Barry Iii CE; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA.; Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa., Barber DL; T Lymphocyte Biology Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA. barberd@niaid.nih.gov.

مؤلفون مشاركون: Tuberculosis Imaging Program

المصدر: Mucosal immunology [Mucosal Immunol] 2021 Sep; Vol. 14 (5), pp. 1055-1066. Date of Electronic Publication: 2021 Jun 22.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural

بيانات الدورية: Publisher: Elsevier Country of Publication: United States NLM ID: 101299742 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1935-3456 (Electronic) Linking ISSN: 19330219 NLM ISO Abbreviation: Mucosal Immunol Subsets: MEDLINE

مواضيع طبية MeSH: Lung/*drug effects , Lung/*immunology , Lung/*metabolism , Mucosal-Associated Invariant T Cells/*drug effects , Mucosal-Associated Invariant T Cells/*immunology , Mucosal-Associated Invariant T Cells/*metabolism , Ribitol/*analogs & derivatives , Uracil/*analogs & derivatives, Animals ; Biomarkers ; Cytokines/biosynthesis ; Disease Management ; Disease Susceptibility ; Host-Pathogen Interactions/genetics ; Host-Pathogen Interactions/immunology ; Immunophenotyping ; Lymphocyte Activation/drug effects ; Lymphocyte Activation/immunology ; Macaca mulatta ; Monkey Diseases/diagnosis ; Monkey Diseases/drug therapy ; Monkey Diseases/etiology ; Monkey Diseases/metabolism ; Mycobacterium tuberculosis/immunology ; Positron-Emission Tomography ; Ribitol/administration & dosage ; Tomography, X-Ray Computed ; Tuberculosis/veterinary ; Uracil/administration & dosage

المؤلفون: Zhao G; Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Kosek D; Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Liu HB; Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Ohlemacher SI; Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Blackburne B; National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland 20894, United States., Nikolskaya A; National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland 20894, United States., Makarova KS; National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland 20894, United States., Sun J; Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Barry Iii CE; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20894, United States., Koonin EV; National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health, Bethesda, Maryland 20894, United States., Dyda F; Laboratory of Molecular Biology, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States., Bewley CA; Laboratory of Bioorganic Chemistry, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, Maryland 20892, United States.

المصدر: Journal of the American Chemical Society [J Am Chem Soc] 2021 Jun 02; Vol. 143 (21), pp. 8056-8068. Date of Electronic Publication: 2021 May 24.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 7503056 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-5126 (Electronic) Linking ISSN: 00027863 NLM ISO Abbreviation: J Am Chem Soc Subsets: MEDLINE

مواضيع طبية MeSH: Adenosine Triphosphate/*metabolism , Biological Products/*metabolism , Ligases/*metabolism , Peptides/*metabolism, Adenosine Triphosphate/chemistry ; Amides/chemistry ; Amides/metabolism ; Biological Products/chemistry ; Esters/chemistry ; Esters/metabolism ; Ligases/chemistry ; Macrocyclic Compounds/chemistry ; Macrocyclic Compounds/metabolism ; Molecular Conformation ; Peptides/chemistry ; Protein Processing, Post-Translational

المؤلفون: Mizrahi V, Barry Iii CE

المصدر: Nature [Nature] 2021 Jan; Vol. 589 (7840), pp. 21-22.

نوع المنشور: News; Comment

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Pharmaceutical Preparations* , Tuberculosis*/drug therapy, Adenosine Triphosphate ; Diarylquinolines ; Humans ; Motion Pictures

المؤلفون: Kolbe K; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States., Bell AC; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States., Prosser GA; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.; Drug Discovery Unit, College of Life Sciences, James Black Centre, University of Dundee, Dundee, United Kingdom., Assmann M; Inflammation and Innate Immunity Unit, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States., Yang HJ; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States., Forbes HE; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States., Gallucci S; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States., Mayer-Barber KD; Inflammation and Innate Immunity Unit, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States., Boshoff HI; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States., Barry Iii CE; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, United States.

المصدر: Frontiers in microbiology [Front Microbiol] 2020 Dec 09; Vol. 11, pp. 591866. Date of Electronic Publication: 2020 Dec 09 (Print Publication: 2020).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101548977 Publication Model: eCollection Cited Medium: Print ISSN: 1664-302X (Print) Linking ISSN: 1664302X NLM ISO Abbreviation: Front Microbiol Subsets: PubMed not MEDLINE

المؤلفون: Dong YY; Structural Genomics Consortium, University of Oxford, Oxford, OX3 7DQ, UK., Wang H; Chemistry Research Laboratory, University of Oxford, Oxford, OX1 3TA, UK., Pike ACW; Structural Genomics Consortium, University of Oxford, Oxford, OX3 7DQ, UK., Cochrane SA; Chemistry Research Laboratory, University of Oxford, Oxford, OX1 3TA, UK; School of Chemistry and Chemical Engineering, Queen's University, Belfast, UK., Hamedzadeh S; Chemistry Research Laboratory, University of Oxford, Oxford, OX1 3TA, UK., Wyszyński FJ; Chemistry Research Laboratory, University of Oxford, Oxford, OX1 3TA, UK., Bushell SR; Structural Genomics Consortium, University of Oxford, Oxford, OX3 7DQ, UK., Royer SF; Chemistry Research Laboratory, University of Oxford, Oxford, OX1 3TA, UK., Widdick DA; Department of Molecular Microbiology, John Innes Centre, Norwich, NR4 7UH, UK., Sajid A; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA., Boshoff HI; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA., Park Y; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA., Lucas R; Chemistry Research Laboratory, University of Oxford, Oxford, OX1 3TA, UK., Liu WM; Chemistry Research Laboratory, University of Oxford, Oxford, OX1 3TA, UK., Lee SS; Chemistry Research Laboratory, University of Oxford, Oxford, OX1 3TA, UK., Machida T; Chemistry Research Laboratory, University of Oxford, Oxford, OX1 3TA, UK., Minall L; Chemistry Research Laboratory, University of Oxford, Oxford, OX1 3TA, UK., Mehmood S; Department of Chemistry, Oxford, OX1 3QZ, UK., Belaya K; Neurosciences Group, Nuffield Department of Clinical Neuroscience, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, OX3 9DS, UK., Liu WW; Neurosciences Group, Nuffield Department of Clinical Neuroscience, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, OX3 9DS, UK., Chu A; Structural Genomics Consortium, University of Oxford, Oxford, OX3 7DQ, UK., Shrestha L; Structural Genomics Consortium, University of Oxford, Oxford, OX3 7DQ, UK., Mukhopadhyay SMM; Structural Genomics Consortium, University of Oxford, Oxford, OX3 7DQ, UK., Strain-Damerell C; Structural Genomics Consortium, University of Oxford, Oxford, OX3 7DQ, UK., Chalk R; Structural Genomics Consortium, University of Oxford, Oxford, OX3 7DQ, UK., Burgess-Brown NA; Structural Genomics Consortium, University of Oxford, Oxford, OX3 7DQ, UK., Bibb MJ; Department of Molecular Microbiology, John Innes Centre, Norwich, NR4 7UH, UK., Barry Iii CE; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland 20892, USA., Robinson CV; Department of Chemistry, Oxford, OX1 3QZ, UK., Beeson D; Neurosciences Group, Nuffield Department of Clinical Neuroscience, Weatherall Institute of Molecular Medicine, University of Oxford, Oxford, OX3 9DS, UK., Davis BG; Chemistry Research Laboratory, University of Oxford, Oxford, OX1 3TA, UK. Electronic address: Ben.Davis@chem.ox.ac.uk., Carpenter EP; Structural Genomics Consortium, University of Oxford, Oxford, OX3 7DQ, UK. Electronic address: liz.carpenter@sgc.ox.ac.uk.

المصدر: Cell [Cell] 2018 Nov 01; Vol. 175 (4), pp. 1045-1058.e16.

نوع المنشور: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 0413066 Publication Model: Print Cited Medium: Internet ISSN: 1097-4172 (Electronic) Linking ISSN: 00928674 NLM ISO Abbreviation: Cell

مواضيع طبية MeSH: Antibiotics, Antitubercular/*pharmacology , Congenital Disorders of Glycosylation/*metabolism , Enzyme Inhibitors/*pharmacology , N-Acetylglucosaminyltransferases/*chemistry, Animals ; Antibiotics, Antitubercular/chemistry ; Binding Sites ; Congenital Disorders of Glycosylation/genetics ; Enzyme Inhibitors/chemistry ; Female ; HEK293 Cells ; Hep G2 Cells ; Humans ; Lipid Metabolism ; Mice ; Molecular Docking Simulation ; Mutation ; N-Acetylglucosaminyltransferases/antagonists & inhibitors ; N-Acetylglucosaminyltransferases/genetics ; N-Acetylglucosaminyltransferases/metabolism ; Protein Binding ; Sf9 Cells ; Spodoptera ; Tunicamycin/chemistry ; Tunicamycin/pharmacology ; Uridine Diphosphate Glucuronic Acid/chemistry ; Uridine Diphosphate Glucuronic Acid/metabolism

المؤلفون: Chen RY; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA., Via LE; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.; Wellcome Centre for Infectious Diseases Research in Africa,Institute of Infectious Disease and Molecular Medicine, University of Cape Town (UCT), Cape Town, South Africa., Dodd LE; Biostatistics Research Branch, Division of Clinical Research, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA., Walzl G; South Africa Department of Science and Technology - National Research Foundation Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa., Malherbe ST; South Africa Department of Science and Technology - National Research Foundation Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa., Loxton AG; South Africa Department of Science and Technology - National Research Foundation Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa., Dawson R; Division of Pulmonology, Department of Medicine, University Of Cape Town Lung Institute, University of Cape Town (UCT), Cape Town, South Africa., Wilkinson RJ; Wellcome Centre for Infectious Diseases Research in Africa,Institute of Infectious Disease and Molecular Medicine, University of Cape Town (UCT), Cape Town, South Africa.; Francis Crick Institute, London, NW1 2AT, UK.; Department of Medicine, Imperial College London, London, W2 1PG, UK., Thienemann F; Wellcome Centre for Infectious Diseases Research in Africa,Institute of Infectious Disease and Molecular Medicine, University of Cape Town (UCT), Cape Town, South Africa.; Department of Internal Medicine, University Hospital Zurich, Zurich, Switzerland., Tameris M; South African Tuberculosis Vaccine Initiative, University of Cape Town (UCT), Cape Town, South Africa., Hatherill M; South African Tuberculosis Vaccine Initiative, University of Cape Town (UCT), Cape Town, South Africa., Diacon AH; TASK Applied Science and Stellenbosch University, Cape Town, South Africa., Liu X; Henan Provincial Chest Hospital, Zhengzhou, Henan, China., Xing J; Henan Provincial Institute of Tuberculosis and Prevention, Henan Center for Disease Control, Zhengzhou, Henan, China., Jin X; Xinmi City Institute of Tuberculosis Prevention and Control, Xinmi, Henan, China., Ma Z; Kaifeng City Institute of Tuberculosis Prevention and Control, Kaifeng, Henan, China., Pan S; Zhongmu County Health and Epidemic Prevention Station, Zhongmu, Henan, China., Zhang G; Henan Provincial Institute of Tuberculosis and Prevention, Henan Center for Disease Control, Zhengzhou, Henan, China., Gao Q; Fudan University, Shanghai, China., Jiang Q; Fudan University, Shanghai, China., Zhu H; Sino-US Tuberculosis Collaborative Research Program, Zhengzhou, Henan, China., Liang L; TASK Applied Science and Stellenbosch University, Cape Town, South Africa., Duan H; Beijing Chest Hospital, Beijing, China., Song T; Institute of Infectious Disease and Molecular Medicine, University of Cape Town (UCT), Cape Town, South Africa., Alland D; Division of Infectious Diseases, Department of Medicine, Rutgers New Jersey Medical School, Newark, NJ, USA., Tartakovsky M; Office of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA., Rosenthal A; Office of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA., Whalen C; Office of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA., Duvenhage M; Office of Cyber Infrastructure and Computational Biology, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA., Cai Y; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA., Goldfeder LC; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA., Arora K; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA., Smith B; South Africa Department of Science and Technology - National Research Foundation Centre of Excellence for Biomedical Tuberculosis Research, South African Medical Research Council Centre for Tuberculosis Research, Division of Molecular Biology and Human Genetics, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa., Winter J; Catalysis Foundation for Health, Emeryville, CA, USA., Barry Iii CE; Tuberculosis Research Section, Laboratory of Clinical Immunology and Microbiology, Division of Intramural Research, National Institute of Allergy and Infectious Diseases (NIAID), National Institutes of Health (NIH), Bethesda, MD, USA.; Wellcome Centre for Infectious Diseases Research in Africa,Institute of Infectious Disease and Molecular Medicine, University of Cape Town (UCT), Cape Town, South Africa.

مؤلفون مشاركون: Predict TB Study Group

المصدر: Gates open research [Gates Open Res] 2017 Nov 06; Vol. 1, pp. 9. Date of Electronic Publication: 2017 Nov 06.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Bill and Melinda Gates Foundation Country of Publication: United States NLM ID: 101717821 Publication Model: Electronic Cited Medium: Internet ISSN: 2572-4754 (Electronic) Linking ISSN: 25724754 NLM ISO Abbreviation: Gates Open Res Subsets: PubMed not MEDLINE

المؤلفون: Gengenbacher M; Max Planck Institute for Infection Biology, Department of Immunology, Berlin, Germany. mg1435@njms.rutgers.edu.; Public Health Research Institute, Rutgers, The State University of New Jersey, Newark, NJ, USA. mg1435@njms.rutgers.edu., Duque-Correa MA; Max Planck Institute for Infection Biology, Department of Immunology, Berlin, Germany.; Wellcome Trust Sanger Institute, Cambridge, United Kingdom., Kaiser P; Max Planck Institute for Infection Biology, Department of Immunology, Berlin, Germany., Schuerer S; Max Planck Institute for Infection Biology, Department of Immunology, Berlin, Germany., Lazar D; Max Planck Institute for Infection Biology, Department of Immunology, Berlin, Germany., Zedler U; Max Planck Institute for Infection Biology, Department of Immunology, Berlin, Germany., Reece ST; Max Planck Institute for Infection Biology, Department of Immunology, Berlin, Germany.; University of Cambridge School of Clinical Medicine, Cambridge, United Kingdom., Nayyar A; Tuberculosis Research Section, Laboratory of Clinical Infectious Diseases, National Institute of Health-National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA.; Albany Molecular Research Inc, Singapore, Singapore., Cole ST; Global Health Institute, École Polytechnique Fédérale de Lausanne, Lausanne, Switzerland., Makarov V; A. N. Bakh Institute of Biochemistry, Russian Academy of Science, Moscow, Russia., Barry Iii CE; Tuberculosis Research Section, Laboratory of Clinical Infectious Diseases, National Institute of Health-National Institute of Allergy and Infectious Diseases, Bethesda, MD, USA.; Institute of Infectious Disease and Molecular Medicine, Faculty of Health Sciences, University of Cape Town, Rondebosch, Republic of South Africa., Dartois V; Public Health Research Institute, Rutgers, The State University of New Jersey, Newark, NJ, USA., Kaufmann SHE; Max Planck Institute for Infection Biology, Department of Immunology, Berlin, Germany. kaufmann@mpiib-berlin.mpg.de.

المصدر: Scientific reports [Sci Rep] 2017 Aug 18; Vol. 7 (1), pp. 8853. Date of Electronic Publication: 2017 Aug 18.

نوع المنشور: Journal Article; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: Hypoxia/*metabolism , Necrosis/*genetics , Necrosis/*metabolism , Nitric Oxide Synthase Type II/*deficiency , Tuberculosis, Pulmonary/*etiology , Tuberculosis, Pulmonary/*metabolism, Animals ; Antitubercular Agents/pharmacology ; Disease Models, Animal ; Fibrosis ; Foam Cells/immunology ; Foam Cells/metabolism ; Foam Cells/pathology ; Humans ; Hypoxia/pathology ; Isoniazid/pharmacology ; Mice ; Mice, Knockout ; Necrosis/pathology ; Rifampin/analogs & derivatives ; Rifampin/pharmacology ; Treatment Outcome ; Tuberculosis, Pulmonary/drug therapy ; Tuberculosis, Pulmonary/pathology

المؤلفون: Esmail H; Department of Medicine, Imperial College London, London, UK.; Clinical Infectious Disease Research Initiative, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.; Radcliffe Department of Medicine, University of Oxford, Oxford, UK., Lai RP; Francis Crick Institute Mill Hill Laboratory, London, UK., Lesosky M; Clinical Infectious Disease Research Initiative, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.; Division of Epidemiology and Biostatistics, School of Public Health and Family Medicine, University of Cape Town, Cape Town, South Africa., Wilkinson KA; Clinical Infectious Disease Research Initiative, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.; Francis Crick Institute Mill Hill Laboratory, London, UK., Graham CM; Francis Crick Institute Mill Hill Laboratory, London, UK., Coussens AK; Clinical Infectious Disease Research Initiative, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa., Oni T; Clinical Infectious Disease Research Initiative, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa., Warwick JM; Department of Medical Imaging and Clinical Oncology, Stellenbosch University, Cape Town, South Africa., Said-Hartley Q; Department of Radiology, Groote Schuur Hospital, Cape Town, South Africa., Koegelenberg CF; Department of Medicine, Stellenbosch University, Cape Town, South Africa., Walzl G; Department of Medicine, Stellenbosch University, Cape Town, South Africa.; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa., Flynn JL; Department of Microbiology and Molecular Genetics, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, USA., Young DB; Department of Medicine, Imperial College London, London, UK.; Francis Crick Institute Mill Hill Laboratory, London, UK., Barry Iii CE; Clinical Infectious Disease Research Initiative, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.; Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Stellenbosch University, Cape Town, South Africa.; Tuberculosis Research Section, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland, USA.; Department of Pathology, University of Cape Town, Cape Town, South Africa., O'Garra A; Francis Crick Institute Mill Hill Laboratory, London, UK.; National Heart and Lung Institute, Imperial College London, London, UK., Wilkinson RJ; Department of Medicine, Imperial College London, London, UK.; Clinical Infectious Disease Research Initiative, Institute of Infectious Disease and Molecular Medicine, University of Cape Town, Cape Town, South Africa.; Francis Crick Institute Mill Hill Laboratory, London, UK.

المصدر: Nature medicine [Nat Med] 2016 Oct; Vol. 22 (10), pp. 1090-1093. Date of Electronic Publication: 2016 Sep 05.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural

بيانات الدورية: Publisher: Nature Publishing Company Country of Publication: United States NLM ID: 9502015 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-170X (Electronic) Linking ISSN: 10788956 NLM ISO Abbreviation: Nat Med Subsets: MEDLINE

مواضيع طبية MeSH: HIV Infections/*complications , Latent Tuberculosis/*diagnostic imaging , Tuberculosis, Pulmonary/*diagnostic imaging, Adult ; Coinfection/diagnostic imaging ; Disease Progression ; Female ; Fluorodeoxyglucose F18 ; Humans ; Interferon-gamma Release Tests ; Latent Tuberculosis/complications ; Male ; Mycobacterium tuberculosis/isolation & purification ; Positron Emission Tomography Computed Tomography ; Radiography, Thoracic ; Radiopharmaceuticals ; South Africa ; Sputum/microbiology ; Tuberculosis/complications ; Tuberculosis/diagnostic imaging ; Tuberculosis, Pulmonary/complications