المؤلفون: Bernard L. Schneider, Rashmi Kothary, Maica Llavero-Hurtado, Thomas H. Gillingwater, Abdelmadjid Atrih, Alexandra Tierney, Jean Michaud, Ariane Beauvais, Thomas M. Wishart, Lucia Chehade, Marc-Olivier Deguise, Douglas J. Lamont, Simon H. Parson, Yves De Repentigny, Mary-Ellen Harper, Chantal A. Pileggi

المصدر: Cellular and Molecular Gastroenterology and Hepatology, Vol 12, Iss 1, Pp 354-377.e3 (2021)
Cellular and Molecular Gastroenterology and Hepatology
Deguise, M-O, Pileggi, C, De Repentigny, Y, Beauvais, A, Tierney, A, Chehade, L, Michaud, J, Llavero hurtado, M, Lamont, D, Atrih, A, Wishart, T, Gillingwater, T, Schneider, B L, Harper, M-E, Parson, S & Kothary, R 2021, ' SMN depleted mice offer a robust and rapid onset model of non-alcoholic fatty liver disease ', Cellular and Molecular Gastroenterology and Hepatology . https://doi.org/10.1016/j.jcmgh.2021.01.019

مصطلحات موضوعية: 0301 basic medicine, LC-MS, liquid chromatography-mass spectrometry, DAVID, Database for Annotation, Visualization and Integrated Discovery, IGF1, insulin-like growth factor 1, AST, aspartate aminotransferase, RC799-869, muscular-atrophy phenotype, CS, citric synthase, animal-models, Mice, 0302 clinical medicine, iron, Fibrosis, Non-alcoholic Fatty Liver Disease, LDL, low-density lipoprotein, Nonalcoholic fatty liver disease, MCD, methionine and choline deficient diet, steatosis, Medicine, TNFR1, tumor necrosis factor receptor superfamily member 1A, defects, ANOVA, analysis of variance, Original Research, Mice, Knockout, P, postnatal day, FasR, Fas receptor, NEFA, non-esterified fatty acid, p53, tumor protein p53, TEAB, triethyl ammonium bicarbonate, Fatty liver, Gastroenterology, NASH, CPT1, carnitine palmitoyl transferase 1, p21, cyclin dependent kinase inhibitor 1A, Diseases of the digestive system. Gastroenterology, 3. Good health, ECM, extracellular matrix, SMN, TMT, tandem mass tagging, mouse-model, qPCR, quantitative polymerase chain reaction, 030211 gastroenterology & hepatology, NASH, nonalcoholic steatohepatitis, medicine.medical_specialty, insulin, HDL, high-density lipoprotein, PBS, phosphate-buffered saline, steatohepatitis, Hypoglycemia, SMN1, survival motor neuron 1, 03 medical and health sciences, Insulin resistance, ROS, reactive oxygen species, VLDL, very low density lipoprotein, Internal medicine, ALT, alanine aminotransferase, NAFLD, mitochondrial dysfunction, Animals, MCL, Markov Clustering Algorithm, Hepatology, ALP, alkaline phosphatase, business.industry, T2DM, type 2 diabetes mellitus, IPA, ingenuity pathway analysis, medicine.disease, WT, wild-type, Survival of Motor Neuron 1 Protein, igfals, insulin-like growth factor binding protein acid labile subunit, digestive system diseases, Fatty Liver, Mice, Inbred C57BL, Disease Models, Animal, 030104 developmental biology, Endocrinology, Metabolism, AAV9, adeno-associated virus 9, SMA, spinal muscular atrophy, network, Akt, protein kinase B, Hepatic stellate cell, NAFLD, nonalcoholic fatty liver disease, Steatosis, Steatohepatitis, business, Bax, BCL2 associated X protein, HFN4a, hepatic nuclear factor 4 alpha

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7a717cf593f4034226b292cb0ee07cc
http://www.sciencedirect.com/science/article/pii/S2352345X21000254

المؤلفون: Barman S; Department of Biochemistry and Nutrition,Central Food Technological Research Institute (CSIR),Mysore 570 020,India., Srinivasan K; Department of Biochemistry and Nutrition,Central Food Technological Research Institute (CSIR),Mysore 570 020,India.

المصدر: The British journal of nutrition [Br J Nutr] 2017 Feb; Vol. 117 (3), pp. 335-350. Date of Electronic Publication: 2017 Mar 01.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Published on behalf of the Nutrition Society by CABI Publishing Country of Publication: England NLM ID: 0372547 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1475-2662 (Electronic) Linking ISSN: 00071145 NLM ISO Abbreviation: Br J Nutr Subsets: MEDLINE

مواضيع طبية MeSH: Diabetes Mellitus, Experimental*/drug therapy , Diabetes Mellitus, Experimental*/metabolism , Diabetes Mellitus, Experimental*/pathology , Dietary Supplements* , Myocardium*/metabolism , Myocardium*/pathology, Antioxidants/*pharmacology , Heart/*drug effects , Oxidative Stress/*drug effects , Zinc/*pharmacology, Aldehydes/metabolism ; Animals ; Antioxidants/metabolism ; Apoptosis ; Biomarkers/metabolism ; Cardiovascular Diseases/metabolism ; Cardiovascular Diseases/pathology ; Cardiovascular Diseases/prevention & control ; Catalase/metabolism ; Fibrosis ; Glutathione/metabolism ; Lipid Peroxidation/drug effects ; Liver/drug effects ; Liver/metabolism ; Liver/pathology ; RNA, Messenger/metabolism ; Rats, Wistar ; Superoxide Dismutase/metabolism ; Trace Elements/pharmacology ; Trace Elements/therapeutic use ; Zinc/therapeutic use