المؤلفون: Beach, Te Kohatea, Watkins, Helena

المصدر: Toitoi, Sum 2020; n.18:p.56-57

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المؤلفون: Prag HA; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 0XY, UK.; Department of Medicine, University of Cambridge, Cambridge, CB2 0QQ, UK., Pala L; School of Chemistry, University of Glasgow, Glasgow, G12 8QQ, UK., Kula-Alwar D; Department of Medicine, University of Cambridge, Cambridge, CB2 0QQ, UK., Mulvey JF; Department of Medicine, University of Cambridge, Cambridge, CB2 0QQ, UK., Luping D; Tianjin Medical University, Tianjin, 300070, China., Beach TE; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, CB2 0QQ, UK., Booty LM; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 0XY, UK., Hall AR; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 0XY, UK., Logan A; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 0XY, UK., Sauchanka V; Department of Medicine, University of Cambridge, Cambridge, CB2 0QQ, UK., Caldwell ST; School of Chemistry, University of Glasgow, Glasgow, G12 8QQ, UK., Robb EL; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 0XY, UK., James AM; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 0XY, UK., Xu Z; Tianjin Medical University, Tianjin, 300070, China., Saeb-Parsy K; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, CB2 0QQ, UK., Hartley RC; School of Chemistry, University of Glasgow, Glasgow, G12 8QQ, UK., Murphy MP; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge Biomedical Campus, Cambridge, CB2 0XY, UK. mpm@mrc-mbu.cam.ac.uk.; Department of Medicine, University of Cambridge, Cambridge, CB2 0QQ, UK. mpm@mrc-mbu.cam.ac.uk., Krieg T; Department of Medicine, University of Cambridge, Cambridge, CB2 0QQ, UK. tk382@medschl.cam.ac.uk.

المصدر: Cardiovascular drugs and therapy [Cardiovasc Drugs Ther] 2022 Feb; Vol. 36 (1), pp. 1-13. Date of Electronic Publication: 2020 Jul 09.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Kluwer Academic For The International Society For Cardiovascular Pharmacotherapy Country of Publication: United States NLM ID: 8712220 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1573-7241 (Electronic) Linking ISSN: 09203206 NLM ISO Abbreviation: Cardiovasc Drugs Ther Subsets: MEDLINE

مواضيع طبية MeSH: Cardiotonic Agents/*pharmacology , Malonates/*pharmacology , Myocardial Infarction/*prevention & control , Myocardial Reperfusion Injury/*drug therapy, Animals ; Cardiotonic Agents/chemical synthesis ; Cardiotonic Agents/chemistry ; Cell Line ; Disease Models, Animal ; Esters/chemistry ; Female ; Humans ; Male ; Malonates/chemical synthesis ; Malonates/chemistry ; Mice ; Mice, Inbred C57BL ; Mitochondria/drug effects ; Mitochondria/metabolism ; Myocardial Reperfusion Injury/physiopathology ; Prodrugs ; Rats ; Rats, Wistar ; Reactive Oxygen Species/metabolism ; Succinic Acid/metabolism

المؤلفون: Hamed M; Department of Surgery, University of Cambridge, Cambridge, UK.; MRC Mitochondrial Biology Unit, Cambridge, UK.; Cambridge National Institute for Health Research (NIHR) Biomedical Research Centre and NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Cambridge, UK., Logan A; MRC Mitochondrial Biology Unit, Cambridge, UK., Gruszczyk AV; Department of Surgery, University of Cambridge, Cambridge, UK.; MRC Mitochondrial Biology Unit, Cambridge, UK.; Cambridge National Institute for Health Research (NIHR) Biomedical Research Centre and NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Cambridge, UK., Beach TE; Department of Surgery, University of Cambridge, Cambridge, UK.; MRC Mitochondrial Biology Unit, Cambridge, UK.; Cambridge National Institute for Health Research (NIHR) Biomedical Research Centre and NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Cambridge, UK., James AM; MRC Mitochondrial Biology Unit, Cambridge, UK., Dare AJ; Department of Surgery, University of Cambridge, Cambridge, UK.; MRC Mitochondrial Biology Unit, Cambridge, UK., Barlow A; Department of Surgery, University of Cambridge, Cambridge, UK., Martin J; Department of Surgery, University of Cambridge, Cambridge, UK.; MRC Mitochondrial Biology Unit, Cambridge, UK.; Cambridge National Institute for Health Research (NIHR) Biomedical Research Centre and NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Cambridge, UK., Georgakopoulos N; Department of Surgery, University of Cambridge, Cambridge, UK.; Cambridge National Institute for Health Research (NIHR) Biomedical Research Centre and NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Cambridge, UK., Gane AM; Department of Surgery, University of Cambridge, Cambridge, UK.; MRC Mitochondrial Biology Unit, Cambridge, UK., Crick K; Department of Surgery, University of Cambridge, Cambridge, UK.; Cambridge National Institute for Health Research (NIHR) Biomedical Research Centre and NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Cambridge, UK., Fouto D; Department of Surgery, University of Cambridge, Cambridge, UK.; Cambridge National Institute for Health Research (NIHR) Biomedical Research Centre and NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Cambridge, UK., Fear C; Department of Surgery, University of Cambridge, Cambridge, UK.; Cambridge National Institute for Health Research (NIHR) Biomedical Research Centre and NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Cambridge, UK., Thiru S; Department of Pathology, Cambridge University Hospitals NHS Trust, Addenbrooke's Hospital, Cambridge, UK., Dolezalova N; Department of Surgery, University of Cambridge, Cambridge, UK.; Cambridge National Institute for Health Research (NIHR) Biomedical Research Centre and NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Cambridge, UK., Ferdinand JR; Cambridge National Institute for Health Research (NIHR) Biomedical Research Centre and NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Cambridge, UK.; Department of Medicine, University of Cambridge, Cambridge, UK., Clatworthy MR; Cambridge National Institute for Health Research (NIHR) Biomedical Research Centre and NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Cambridge, UK.; Department of Medicine, University of Cambridge, Cambridge, UK., Hosgood SA; Department of Surgery, University of Cambridge, Cambridge, UK.; Cambridge National Institute for Health Research (NIHR) Biomedical Research Centre and NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Cambridge, UK., Nicholson ML; Department of Surgery, University of Cambridge, Cambridge, UK.; Cambridge National Institute for Health Research (NIHR) Biomedical Research Centre and NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Cambridge, UK., Murphy MP; MRC Mitochondrial Biology Unit, Cambridge, UK.; Department of Medicine, University of Cambridge, Cambridge, UK., Saeb-Parsy K; Department of Surgery, University of Cambridge, Cambridge, UK.; Cambridge National Institute for Health Research (NIHR) Biomedical Research Centre and NIHR Blood and Transplant Research Unit in Organ Donation and Transplantation, Cambridge, UK.

المصدر: The British journal of surgery [Br J Surg] 2021 Sep 27; Vol. 108 (9), pp. 1072-1081.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press on behalf of BJS Foundation Ltd Country of Publication: England NLM ID: 0372553 Publication Model: Print Cited Medium: Internet ISSN: 1365-2168 (Electronic) Linking ISSN: 00071323 NLM ISO Abbreviation: Br J Surg Subsets: MEDLINE

مواضيع طبية MeSH: Kidney/*blood supply , Kidney Transplantation/*adverse effects , Organ Preservation/*methods , Organophosphorus Compounds/*pharmacology , Reperfusion Injury/*therapy , Ubiquinone/*analogs & derivatives, Animals ; Antioxidants/pharmacology ; Disease Models, Animal ; Humans ; Swine ; Ubiquinone/pharmacology

المؤلفون: Prag HA; MRC Mitochondrial Biology Unit, University of Cambridge, The Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK.; Department of Medicine, University of Cambridge, Addenbrookes Hospital, Hills Road, Cambridge CB2 0QQ, UK., Gruszczyk AV; MRC Mitochondrial Biology Unit, University of Cambridge, The Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK.; Department of Surgery, University of Cambridge, Cambridge NIHR Biomedical Research Centre, Biomedical Campus, Hills Road, Cambridge CB2 0QQ, UK., Huang MM; Department of Surgery, University of Cambridge, Cambridge NIHR Biomedical Research Centre, Biomedical Campus, Hills Road, Cambridge CB2 0QQ, UK., Beach TE; Department of Surgery, University of Cambridge, Cambridge NIHR Biomedical Research Centre, Biomedical Campus, Hills Road, Cambridge CB2 0QQ, UK., Young T; Department of Medicine, University of Cambridge, Addenbrookes Hospital, Hills Road, Cambridge CB2 0QQ, UK.; MRC Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Cambridge Biomedical Campus, PO Box 197, Cambridge CB2 0XZ, UK., Tronci L; MRC Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Cambridge Biomedical Campus, PO Box 197, Cambridge CB2 0XZ, UK., Nikitopoulou E; MRC Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Cambridge Biomedical Campus, PO Box 197, Cambridge CB2 0XZ, UK., Mulvey JF; Department of Medicine, University of Cambridge, Addenbrookes Hospital, Hills Road, Cambridge CB2 0QQ, UK., Ascione R; Bristol Medical School and Translational Biomedical Research Centre, Faculty of Health Science, University of Bristol, Level 7, Bristol Royal Infirmary, Upper Maudlin Street, Bristol BS2 8HW, UK., Hadjihambi A; Département de Physiologie, Université de Lausanne, 7 Rue du Bugnon, 1005 Lausanne, Switzerland., Shattock MJ; King's College London, British Heart Foundation Centre of Excellence, The Rayne Institute, St Thomas' Hospital, Lambeth Palace Road, London SE1 7EH, UK., Pellerin L; Département de Physiologie, Université de Lausanne, 7 Rue du Bugnon, 1005 Lausanne, Switzerland.; Centre de Résonance Magnétique des Systèmes Biologiques, UMR5536 CNRS, LabEx TRAIL-IBIO, Université de Bordeaux, 146 Rue Leo Saignat, Bordeaux 33076, France.; Inserm U1082, Université de Poitiers, 2 Rue de la Miletrie, Poitiers 86021, France., Saeb-Parsy K; Department of Surgery, University of Cambridge, Cambridge NIHR Biomedical Research Centre, Biomedical Campus, Hills Road, Cambridge CB2 0QQ, UK., Frezza C; MRC Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Cambridge Biomedical Campus, PO Box 197, Cambridge CB2 0XZ, UK., James AM; MRC Mitochondrial Biology Unit, University of Cambridge, The Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK., Krieg T; Department of Medicine, University of Cambridge, Addenbrookes Hospital, Hills Road, Cambridge CB2 0QQ, UK., Murphy MP; MRC Mitochondrial Biology Unit, University of Cambridge, The Keith Peters Building, Cambridge Biomedical Campus, Hills Road, Cambridge CB2 0XY, UK.; Department of Medicine, University of Cambridge, Addenbrookes Hospital, Hills Road, Cambridge CB2 0QQ, UK., Aksentijević D; William Harvey Research Institute, Barts and The London School of Medicine and Dentistry, Queen Mary University of London, Charterhouse Square, London, UK.; Centre for inflammation and Therapeutic Innovation, Queen Mary University of London, Charterhouse Square, London, UK.

المصدر: Cardiovascular research [Cardiovasc Res] 2021 Mar 21; Vol. 117 (4), pp. 1188-1201.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford Journals Country of Publication: England NLM ID: 0077427 Publication Model: Print Cited Medium: Internet ISSN: 1755-3245 (Electronic) Linking ISSN: 00086363 NLM ISO Abbreviation: Cardiovasc Res Subsets: MEDLINE

مواضيع طبية MeSH: Mitochondria, Heart/*metabolism , Monocarboxylic Acid Transporters/*metabolism , Myocardial Infarction/*therapy , Myocardial Reperfusion/*adverse effects , Myocardial Reperfusion Injury/*metabolism , Myocytes, Cardiac/*metabolism , Succinic Acid/*metabolism , Symporters/*metabolism, Animals ; Cells, Cultured ; Disease Models, Animal ; Female ; Isolated Heart Preparation ; Male ; Metabolome ; Mice, Inbred C57BL ; Mice, Knockout ; Monocarboxylic Acid Transporters/genetics ; Myocardial Infarction/genetics ; Myocardial Infarction/metabolism ; Myocardial Reperfusion Injury/genetics ; Oxidation-Reduction ; Rats ; Reactive Oxygen Species/metabolism ; Receptors, G-Protein-Coupled/metabolism ; Sus scrofa ; Symporters/genetics ; Time Factors ; Mice

المؤلفون: Sampaziotis F; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, Cambridgeshire, UK. fs347@cam.ac.uk lv225@cam.ac.uk.; Department of Medicine, University of Cambridge, Cambridge, Cambridgeshire, UK.; Cambridge Liver Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK., Muraro D; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, Cambridgeshire, UK., Tysoe OC; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, Cambridgeshire, UK.; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, Cambridgeshire, UK., Sawiak S; Department of Clinical Neurosciences, University of Cambridge, Cambridge, Cambridgeshire, UK., Beach TE; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, Cambridgeshire, UK., Godfrey EM; Department of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK., Upponi SS; Department of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK., Brevini T; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, Cambridgeshire, UK., Wesley BT; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, Cambridgeshire, UK., Garcia-Bernardo J; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, UK., Mahbubani K; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, Cambridgeshire, UK., Canu G; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, Cambridgeshire, UK., Gieseck R 3rd; Immunopathogenesis Section, Laboratory of Parasitic Diseases, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA., Berntsen NL; Norwegian PSC Research Center, Department of Transplantation Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Research Institute of Internal Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway., Mulcahy VL; Department of Medicine, University of Cambridge, Cambridge, Cambridgeshire, UK.; Academic Department of Medical Genetics, University of Cambridge, Cambridge, Cambridgeshire, UK., Crick K; Department of Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK., Fear C; Department of Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK., Robinson S; Department of Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK., Swift L; Department of Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK., Gambardella L; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, Cambridgeshire, UK.; Department of Medicine, University of Cambridge, Cambridge, Cambridgeshire, UK., Bargehr J; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, Cambridgeshire, UK.; Department of Medicine, University of Cambridge, Cambridge, Cambridgeshire, UK.; Division of Cardiovascular Medicine, University of Cambridge, Cambridge, Cambridgeshire, UK., Ortmann D; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, Cambridgeshire, UK., Brown SE; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, Cambridgeshire, UK., Osnato A; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, Cambridgeshire, UK., Murphy MP; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, Cambridgeshire, UK., Corbett G; Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK., Gelson WTH; Department of Medicine, University of Cambridge, Cambridge, Cambridgeshire, UK.; Cambridge Liver Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK., Mells GF; Department of Medicine, University of Cambridge, Cambridge, Cambridgeshire, UK.; Cambridge Liver Unit, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK.; Academic Department of Medical Genetics, University of Cambridge, Cambridge, Cambridgeshire, UK., Humphreys P; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, Cambridgeshire, UK., Davies SE; Department of Histopathology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK., Amin I; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, Cambridgeshire, UK.; Department of Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK., Gibbs P; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, Cambridgeshire, UK.; Department of Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK., Sinha S; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, Cambridgeshire, UK.; Department of Medicine, University of Cambridge, Cambridge, Cambridgeshire, UK., Teichmann SA; Wellcome Sanger Institute, Wellcome Genome Campus, Hinxton, Cambridgeshire, UK.; Cavendish Laboratory, Department of Physics, University of Cambridge, Cambridge, Cambridgeshire, UK., Butler AJ; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, Cambridgeshire, UK.; Department of Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK., See TC; Department of Radiology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK., Melum E; Norwegian PSC Research Center, Department of Transplantation Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Research Institute of Internal Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Oslo, Norway.; Institute of Clinical Medicine, Faculty of Medicine, University of Oslo, Oslo, Norway.; Section for Gastroenterology, Department of Transplantation Medicine, Division of Surgery, Inflammatory Diseases and Transplantation, Oslo University Hospital, Rikshospitalet, Oslo, Norway.; Hybrid Technology Hub-Centre of Excellence, Institute of Basic Medical Sciences, Faculty of Medicine, University of Oslo, Oslo, Norway., Watson CJE; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, Cambridgeshire, UK.; Department of Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK.; National Institute of Health Research (NIHR) Cambridge Biomedical Research Centre and the NIHR Blood and Transplant Research Unit (BTRU), Cambridge, Cambridgeshire, UK.; University of Cambridge in collaboration with Newcastle University and in partnership with NHS Blood and Transplant (NHSBT), Cambridge, Cambridgeshire, UK., Saeb-Parsy K; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, Cambridgeshire, UK.; Department of Surgery, Cambridge University Hospitals NHS Foundation Trust, Cambridge, Cambridgeshire, UK., Vallier L; Wellcome-MRC Cambridge Stem Cell Institute, Cambridge, Cambridgeshire, UK. fs347@cam.ac.uk lv225@cam.ac.uk.; Department of Surgery, University of Cambridge and NIHR Cambridge Biomedical Research Centre, Cambridge, Cambridgeshire, UK.

المصدر: Science (New York, N.Y.) [Science] 2021 Feb 19; Vol. 371 (6531), pp. 839-846.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 0404511 Publication Model: Print Cited Medium: Internet ISSN: 1095-9203 (Electronic) Linking ISSN: 00368075 NLM ISO Abbreviation: Science Subsets: MEDLINE

مواضيع طبية MeSH: Cell- and Tissue-Based Therapy*, Bile Duct Diseases/*therapy , Bile Ducts/*cytology , Bile Ducts, Intrahepatic/*physiology , Epithelial Cells/*cytology , Organoids/*transplantation, Animals ; Bile ; Bile Ducts/physiology ; Bile Ducts, Intrahepatic/cytology ; Common Bile Duct/cytology ; Epithelial Cells/physiology ; Gallbladder/cytology ; Gene Expression Regulation ; Humans ; Liver/physiology ; Liver Transplantation ; Mesenchymal Stem Cell Transplantation ; Mice ; Organoids/physiology ; RNA-Seq ; Tissue and Organ Procurement ; Transcriptome

المؤلفون: Prag HA; Molecular Research Center, Mitochondrial Biology Unit, Biomedical Campus, University of Cambridge, Cambridge CB2 0XY, United Kingdom., Kula-Alwar D; Department of Medicine, University of Cambridge, Cambridge CB2 0QQ, United Kingdom., Pala L; School of Chemistry, University of Glasgow, Glasgow G12 8QQ, United Kingdom., Caldwell ST; School of Chemistry, University of Glasgow, Glasgow G12 8QQ, United Kingdom., Beach TE; Department of Surgery, Cambridge National Institute for Health Research Biomedical Research Centre, University of Cambridge, Cambridge CB2 0QQ, United Kingdom., James AM; Molecular Research Center, Mitochondrial Biology Unit, Biomedical Campus, University of Cambridge, Cambridge CB2 0XY, United Kingdom., Saeb-Parsy K; Department of Surgery, Cambridge National Institute for Health Research Biomedical Research Centre, University of Cambridge, Cambridge CB2 0QQ, United Kingdom., Krieg T; Department of Medicine, University of Cambridge, Cambridge CB2 0QQ, United Kingdom., Hartley RC; School of Chemistry, University of Glasgow, Glasgow G12 8QQ, United Kingdom., Murphy MP; Molecular Research Center, Mitochondrial Biology Unit, Biomedical Campus, University of Cambridge, Cambridge CB2 0XY, United Kingdom.; Department of Medicine, University of Cambridge, Cambridge CB2 0QQ, United Kingdom.

المصدر: Molecular pharmaceutics [Mol Pharm] 2020 Sep 08; Vol. 17 (9), pp. 3526-3540. Date of Electronic Publication: 2020 Aug 05.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101197791 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1543-8392 (Electronic) Linking ISSN: 15438384 NLM ISO Abbreviation: Mol Pharm Subsets: MEDLINE

مواضيع طبية MeSH: Carboxylic Acids/*chemistry , Cations/*chemistry , Mitochondria/*drug effects, Animals ; Cell Line, Tumor ; Cell Membrane/drug effects ; Drug Delivery Systems/methods ; Esters/chemistry ; Female ; HeLa Cells ; Heterocyclic Compounds/chemistry ; Humans ; Hydrophobic and Hydrophilic Interactions ; Male ; Malonates/chemistry ; Membrane Potentials/drug effects ; Mice ; Mice, Inbred C57BL ; Organophosphorus Compounds/chemistry ; Rats ; Rats, Wistar

المؤلفون: Beach TE; Department of Surgery and Cambridge NIHR Biomedical Research Centre, Biomedical Campus, University of Cambridge, Cambridge, CB2 0QQ, UK., Prag HA; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, CB2 0XY, UK., Pala L; School of Chemistry, University of Glasgow, Glasgow, G12 8QQ, UK., Logan A; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, CB2 0XY, UK., Huang MM; Department of Surgery and Cambridge NIHR Biomedical Research Centre, Biomedical Campus, University of Cambridge, Cambridge, CB2 0QQ, UK., Gruszczyk AV; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, CB2 0XY, UK., Martin JL; Department of Surgery and Cambridge NIHR Biomedical Research Centre, Biomedical Campus, University of Cambridge, Cambridge, CB2 0QQ, UK., Mahbubani K; Department of Surgery and Cambridge NIHR Biomedical Research Centre, Biomedical Campus, University of Cambridge, Cambridge, CB2 0QQ, UK., Hamed MO; Department of Surgery and Cambridge NIHR Biomedical Research Centre, Biomedical Campus, University of Cambridge, Cambridge, CB2 0QQ, UK., Hosgood SA; Department of Surgery and Cambridge NIHR Biomedical Research Centre, Biomedical Campus, University of Cambridge, Cambridge, CB2 0QQ, UK., Nicholson ML; Department of Surgery and Cambridge NIHR Biomedical Research Centre, Biomedical Campus, University of Cambridge, Cambridge, CB2 0QQ, UK., James AM; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, CB2 0XY, UK., Hartley RC; School of Chemistry, University of Glasgow, Glasgow, G12 8QQ, UK., Murphy MP; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, CB2 0XY, UK. Electronic address: mpm@mrc-mbu.cam.ac.uk., Saeb-Parsy K; Department of Surgery and Cambridge NIHR Biomedical Research Centre, Biomedical Campus, University of Cambridge, Cambridge, CB2 0QQ, UK. Electronic address: ks10014@cam.ac.uk.

المصدر: Redox biology [Redox Biol] 2020 Sep; Vol. 36, pp. 101640. Date of Electronic Publication: 2020 Jul 12.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Elsevier, B.V Country of Publication: Netherlands NLM ID: 101605639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2317 (Electronic) Linking ISSN: 22132317 NLM ISO Abbreviation: Redox Biol Subsets: MEDLINE

مواضيع طبية MeSH: Prodrugs*/pharmacology , Reperfusion Injury*/drug therapy, Animals ; Esters ; Humans ; Malonates ; Mice ; Succinate Dehydrogenase/metabolism ; Swine

المؤلفون: Martin JL; Department of Surgery and Cambridge NIHR Biomedical Research Centre, Biomedical Campus, University of Cambridge, Cambridge, UK., Costa ASH; MRC Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Cambridge, UK., Gruszczyk AV; Department of Surgery and Cambridge NIHR Biomedical Research Centre, Biomedical Campus, University of Cambridge, Cambridge, UK.; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK., Beach TE; Department of Surgery and Cambridge NIHR Biomedical Research Centre, Biomedical Campus, University of Cambridge, Cambridge, UK., Allen FM; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK., Prag HA; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK., Hinchy EC; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK., Mahbubani K; Department of Surgery and Cambridge NIHR Biomedical Research Centre, Biomedical Campus, University of Cambridge, Cambridge, UK., Hamed M; Department of Surgery and Cambridge NIHR Biomedical Research Centre, Biomedical Campus, University of Cambridge, Cambridge, UK., Tronci L; MRC Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Cambridge, UK., Nikitopoulou E; MRC Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Cambridge, UK., James AM; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK., Krieg T; Department of Medicine, University of Cambridge, Cambridge, UK., Robinson AJ; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK., Huang MM; Department of Surgery and Cambridge NIHR Biomedical Research Centre, Biomedical Campus, University of Cambridge, Cambridge, UK.; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK., Caldwell ST; School of Chemistry, University of Glasgow, Glasgow, UK., Logan A; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK., Pala L; School of Chemistry, University of Glasgow, Glasgow, UK., Hartley RC; School of Chemistry, University of Glasgow, Glasgow, UK., Frezza C; MRC Cancer Unit, University of Cambridge, Hutchison/MRC Research Centre, Cambridge, UK., Saeb-Parsy K; Department of Surgery and Cambridge NIHR Biomedical Research Centre, Biomedical Campus, University of Cambridge, Cambridge, UK., Murphy MP; MRC Mitochondrial Biology Unit, University of Cambridge, Cambridge, UK. mpm@mrc-mbu.cam.ac.uk.; Department of Medicine, University of Cambridge, Cambridge, UK. mpm@mrc-mbu.cam.ac.uk.

المصدر: Nature metabolism [Nat Metab] 2019 Sep 30; Vol. 1, pp. 966-974.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Springer Nature Country of Publication: Germany NLM ID: 101736592 Publication Model: Print Cited Medium: Internet ISSN: 2522-5812 (Electronic) Linking ISSN: 25225812 NLM ISO Abbreviation: Nat Metab

مواضيع طبية MeSH: Organ Transplantation*, Reperfusion Injury/*metabolism , Succinic Acid/*metabolism, Animals ; Humans ; Mice ; Swine