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المؤلفون: Beck ES; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Mullins WA; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA., Dos Santos Silva J; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY 10029, USA., Filippini S; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.; Department of Neurosciences, Drug, and Child Health, University of Florence, Florence 50121, Italy., Parvathaneni P; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA., Maranzano J; McConnell Brain Imaging Centre, Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal, QC H3A2B4, Canada.; Department of Anatomy, University of Quebec, Trois-Rivieres, QC G9A5H7, Canada., Morrison M; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA., Suto DJ; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA., Donnay C; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA., Dieckhaus H; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA., Luciano NJ; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA., Sharma K; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA., Gaitán MI; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA., Liu J; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.; Advanced Imaging Research Center and Department of Radiology, University of Texas Southwestern Medical Center, Dallas, TX 75390, USA., de Zwart JA; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA., van Gelderen P; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA., Cortese I; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA., Narayanan S; McConnell Brain Imaging Centre, Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal, QC H3A2B4, Canada., Duyn JH; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA., Nair G; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA., Sati P; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.; Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA., Reich DS; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD 20892, USA.

المصدر: Brain communications [Brain Commun] 2024 May 02; Vol. 6 (3), pp. fcae158. Date of Electronic Publication: 2024 May 02 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 101755125 Publication Model: eCollection Cited Medium: Internet ISSN: 2632-1297 (Electronic) Linking ISSN: 26321297 NLM ISO Abbreviation: Brain Commun Subsets: PubMed not MEDLINE

المؤلفون: Assländer J; Center for Biomedical Imaging, Dept. of Radiology, New York University School of Medicine, 650 1st Avenue, New York, 10016, NY, USA.; Center for Advanced Imaging Innovation and Research (CAI R), Dept. of Radiology, New York University School of Medicine, 650 1st Avenue, New York, 10016, NY, USA., Mao A; Center for Biomedical Imaging, Dept. of Radiology, New York University School of Medicine, 650 1st Avenue, New York, 10016, NY, USA.; Center for Advanced Imaging Innovation and Research (CAI R), Dept. of Radiology, New York University School of Medicine, 650 1st Avenue, New York, 10016, NY, USA.; Vilcek Institute of Graduate Biomedical Sciences, New York University School of Medicine, 550 1st Avenue, New York, 10016, NY, USA., Marchetto E; Center for Biomedical Imaging, Dept. of Radiology, New York University School of Medicine, 650 1st Avenue, New York, 10016, NY, USA.; Center for Advanced Imaging Innovation and Research (CAI R), Dept. of Radiology, New York University School of Medicine, 650 1st Avenue, New York, 10016, NY, USA., Beck ES; Corinne Goldsmith Dickinson Center for Multiple Sclerosis, Department of Neurology, Icahn School of Medicine at Mount Sinai, 5 East 98th Street, New York, 10029, NY, USA., La Rosa F; Corinne Goldsmith Dickinson Center for Multiple Sclerosis, Department of Neurology, Icahn School of Medicine at Mount Sinai, 5 East 98th Street, New York, 10029, NY, USA., Charlson RW; Department of Neurology, New York University School of Medicine, 240 E 38th Street, New York, 10016, NY, USA., Shepherd TM; Center for Biomedical Imaging, Dept. of Radiology, New York University School of Medicine, 650 1st Avenue, New York, 10016, NY, USA., Flassbeck S; Center for Biomedical Imaging, Dept. of Radiology, New York University School of Medicine, 650 1st Avenue, New York, 10016, NY, USA.; Center for Advanced Imaging Innovation and Research (CAI R), Dept. of Radiology, New York University School of Medicine, 650 1st Avenue, New York, 10016, NY, USA.

المصدر: ArXiv [ArXiv] 2024 Apr 01. Date of Electronic Publication: 2024 Apr 01.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101759493 Publication Model: Electronic Cited Medium: Internet ISSN: 2331-8422 (Electronic) Linking ISSN: 23318422 NLM ISO Abbreviation: ArXiv Subsets: PubMed not MEDLINE

المؤلفون: Okar SV; From the Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institute of Health, Bethesda, MD, USA (S.V.O., E.S.B., M.I.G., M.A., D.S.R.); qMRI Core facility, National Institute of Neurological Disorders and Stroke, National Institute of Health, Bethesda, MD, USA (H.D., G.N.); Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA (E.S.B.); Office of Biostatistics, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA (G.N.); Department of Radiology and Radiological Sciences, Uniformed Services University of the Health Sciences, Bethesda, MD, USA (D.L.P.); Division of Neuroscience, Vita-Salute San Raffaele University and Hospital, Milan, Italy (M.A.); Department of Neurology, Johns Hopkins University School of Medicine, Baltimore, MD, USA (M.A.); Experimental Immunotherapeutics Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA (I.C.M.C.); Neuroimmunology Clinic, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA (A.F.); and Viral Immunology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD20814, USA (S.J.)., Dieckhaus H, Beck ES, Gaitán MI, Norato G, Pham DL, Absinta M, Cortese IC, Fletcher A, Jacobson S, Nair G, Reich DS

المصدر: Investigative radiology [Invest Radiol] 2024 Mar 01; Vol. 59 (3), pp. 243-251.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Lippincott Williams & Wilkins Country of Publication: United States NLM ID: 0045377 Publication Model: Print Cited Medium: Internet ISSN: 1536-0210 (Electronic) Linking ISSN: 00209996 NLM ISO Abbreviation: Invest Radiol Subsets: MEDLINE

مواضيع طبية MeSH: Multiple Sclerosis*/pathology, Humans ; Female ; Adult ; Middle Aged ; Magnetic Resonance Imaging ; Meninges/diagnostic imaging ; Meninges/pathology ; Inflammation/pathology

المؤلفون: Donnay C; Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health, Bethesda, MD, United States., Dieckhaus H; qMRI Core, NINDS, National Institutes of Health, Bethesda, MD, United States., Tsagkas C; Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health, Bethesda, MD, United States., Gaitán MI; Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health, Bethesda, MD, United States., Beck ES; Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health, Bethesda, MD, United States.; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Mullins A; Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health, Bethesda, MD, United States.; qMRI Core, NINDS, National Institutes of Health, Bethesda, MD, United States., Reich DS; Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke (NINDS), National Institutes of Health, Bethesda, MD, United States., Nair G; qMRI Core, NINDS, National Institutes of Health, Bethesda, MD, United States.

المصدر: Frontiers in neuroimaging [Front Neuroimaging] 2023 Dec 01; Vol. 2, pp. 1252261. Date of Electronic Publication: 2023 Dec 01 (Print Publication: 2023).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 9918402387106676 Publication Model: eCollection Cited Medium: Internet ISSN: 2813-1193 (Electronic) Linking ISSN: 28131193 NLM ISO Abbreviation: Front Neuroimaging Subsets: PubMed not MEDLINE

المؤلفون: Beck ES; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Mullins WA; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA., Dos Santos Silva J; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Filippini S; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.; Department of Neurosciences, Drug, and Child Health, University of Florence, Florence, Italy., Parvathaneni P; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA., Maranzano J; McConnell Brain Imaging Centre, Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal, QC, Canada.; Department of Anatomy, University of Quebec, Trois-Rivieres, QC, Canada., Morrison M; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA., Suto DJ; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA., Donnay C; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA., Dieckhaus H; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA., Luciano NJ; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA., Sharma K; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA., Gaitán MI; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA., Liu J; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.; Advanced Imaging Research Center and Department of Radiology, University of Texas Southwestern Medical Center, Dallas, TX, USA., de Zwart JA; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA., van Gelderen P; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA., Cortese I; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA., Narayanan S; McConnell Brain Imaging Centre, Department of Neurology and Neurosurgery, Montreal Neurological Institute and Hospital, McGill University, Montreal, QC, Canada., Duyn JH; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA., Nair G; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, USA., Sati P; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.; Department of Neurology, Cedars-Sinai Medical Center, Los Angeles, CA, USA., Reich DS; National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA.

المصدر: MedRxiv : the preprint server for health sciences [medRxiv] 2023 Sep 25. Date of Electronic Publication: 2023 Sep 25.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101767986 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: medRxiv Subsets: PubMed not MEDLINE

المؤلفون: Manning AR; Penn Statistics in Imaging and Visualization Center, Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Beck ES; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA., Schindler MK; Department of Neurology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Nair G; Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA., Clark KA; Penn Statistics in Imaging and Visualization Center, Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Parvathaneni P; Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA., Reich DS; Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Maryland, USA., Shinohara RT; Penn Statistics in Imaging and Visualization Center, Department of Biostatistics, Epidemiology, and Informatics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.; Center for Biomedical Image Computing and Analytics, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA., Solomon AJ; Department of Neurological Sciences, Larner College of Medicine at The University of Vermont, Burlington, Vermont, USA.

المصدر: Journal of neuroimaging : official journal of the American Society of Neuroimaging [J Neuroimaging] 2023 May-Jun; Vol. 33 (3), pp. 434-445. Date of Electronic Publication: 2023 Jan 30.

نوع المنشور: Journal Article; Research Support, N.I.H., Intramural; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Wiley Country of Publication: United States NLM ID: 9102705 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-6569 (Electronic) Linking ISSN: 10512284 NLM ISO Abbreviation: J Neuroimaging Subsets: MEDLINE

مواضيع طبية MeSH: Multiple Sclerosis*/diagnostic imaging , Multiple Sclerosis*/pathology, Adult ; Humans ; Magnetic Resonance Imaging/methods

المؤلفون: van Gelderen P; Advanced MRI Section, Laboratory of Functional and Molecular Imaging, NINDS, NIH, Bethesda, MD, United States of America., Li X; F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, United States of America; Department of Radiology and Radiological Sciences, Johns Hopkins University, Baltimore, MD, United States of America., de Zwart JA; Advanced MRI Section, Laboratory of Functional and Molecular Imaging, NINDS, NIH, Bethesda, MD, United States of America., Beck ES; Translational Neurology Section, NINDS, NIH, Bethesda, MD, United States of America; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York City, NY, United States of America., Okar SV; Translational Neurology Section, NINDS, NIH, Bethesda, MD, United States of America., Huang Y; Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States of America., Lai K; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, United States of America; Department of Electrical & Computer Engineering, Georgia Institute of Technology, Atlanta, GA, United States of America., Sulam J; Department of Biomedical Engineering, Johns Hopkins University, Baltimore, MD, United States of America., van Zijl PCM; F.M. Kirby Research Center for Functional Brain Imaging, Kennedy Krieger Institute, Baltimore, MD, United States of America; Department of Radiology and Radiological Sciences, Johns Hopkins University, Baltimore, MD, United States of America., Reich DS; Translational Neurology Section, NINDS, NIH, Bethesda, MD, United States of America., Duyn JH; Advanced MRI Section, Laboratory of Functional and Molecular Imaging, NINDS, NIH, Bethesda, MD, United States of America., Liu J; Advanced Imaging Research Center, UT Southwestern Medical Center, Dallas, TX, United States of America. Electronic address: jiaen.liu@utsouthwestern.edu.

المصدر: NeuroImage [Neuroimage] 2023 Apr 15; Vol. 270, pp. 119992. Date of Electronic Publication: 2023 Feb 27.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural

بيانات الدورية: Publisher: Academic Press Country of Publication: United States NLM ID: 9215515 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1095-9572 (Electronic) Linking ISSN: 10538119 NLM ISO Abbreviation: Neuroimage Subsets: MEDLINE

مواضيع طبية MeSH: Brain* , Magnetic Resonance Imaging*/methods, Humans ; Reproducibility of Results ; Retrospective Studies ; Motion

المؤلفون: Bouman PM; From the MS Center Amsterdam, Anatomy & Neurosciences, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands (P.M.B., S.N., F.A.N.S., M.M.S., J.J.G.G., M.D.S.); Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Md (E.S.B., D.S.R.); Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY (E.S.B.); Bio-imaging Institute, University of Bordeaux, Bordeaux, France (G.B.); Neurology Section, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy (M. Castellaro, M. Calabrese); Department of Information Engineering, University of Padova, Padova, Italy (M. Castellaro); NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK (D.T.C.); National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK (D.T.C.); Departments of Neuroradiology (P.E., B.W.) and Neurology (M.M.), School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; Neuroimaging Research Unit, Division of Neuroscience Neurology Unit, IRCCS San Raffaele Scientific Institute Vita-Salute San Raffaele University, Milan, Italy (M.F., P.P., M.A.R.); Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genoa, Italy (M.I., C.L.); IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, Genoa, Italy (M.I., C.L.); Center for Neurologic Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.M., A.M.P., C.R.G.G.); Department of Radiology and Nuclear Medicine, MS Center Amsterdam, Amsterdam Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (B.M.); Department of Epidemiology and Data Science, Amsterdam University Medical Center, Amsterdam, the Netherlands (J.W.R.T.); Anatomy & Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (L.E.J.); and Amsterdam Neuroscience, Brain Imaging and Neurodegeneration, Amsterdam, the Netherlands (L.E.J.)., Noteboom S; From the MS Center Amsterdam, Anatomy & Neurosciences, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands (P.M.B., S.N., F.A.N.S., M.M.S., J.J.G.G., M.D.S.); Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Md (E.S.B., D.S.R.); Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY (E.S.B.); Bio-imaging Institute, University of Bordeaux, Bordeaux, France (G.B.); Neurology Section, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy (M. Castellaro, M. Calabrese); Department of Information Engineering, University of Padova, Padova, Italy (M. Castellaro); NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK (D.T.C.); National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK (D.T.C.); Departments of Neuroradiology (P.E., B.W.) and Neurology (M.M.), School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; Neuroimaging Research Unit, Division of Neuroscience Neurology Unit, IRCCS San Raffaele Scientific Institute Vita-Salute San Raffaele University, Milan, Italy (M.F., P.P., M.A.R.); Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genoa, Italy (M.I., C.L.); IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, Genoa, Italy (M.I., C.L.); Center for Neurologic Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.M., A.M.P., C.R.G.G.); Department of Radiology and Nuclear Medicine, MS Center Amsterdam, Amsterdam Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (B.M.); Department of Epidemiology and Data Science, Amsterdam University Medical Center, Amsterdam, the Netherlands (J.W.R.T.); Anatomy & Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (L.E.J.); and Amsterdam Neuroscience, Brain Imaging and Neurodegeneration, Amsterdam, the Netherlands (L.E.J.)., Nobrega Santos FA; From the MS Center Amsterdam, Anatomy & Neurosciences, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands (P.M.B., S.N., F.A.N.S., M.M.S., J.J.G.G., M.D.S.); Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Md (E.S.B., D.S.R.); Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY (E.S.B.); Bio-imaging Institute, University of Bordeaux, Bordeaux, France (G.B.); Neurology Section, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy (M. Castellaro, M. Calabrese); Department of Information Engineering, University of Padova, Padova, Italy (M. Castellaro); NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK (D.T.C.); National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK (D.T.C.); Departments of Neuroradiology (P.E., B.W.) and Neurology (M.M.), School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; Neuroimaging Research Unit, Division of Neuroscience Neurology Unit, IRCCS San Raffaele Scientific Institute Vita-Salute San Raffaele University, Milan, Italy (M.F., P.P., M.A.R.); Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genoa, Italy (M.I., C.L.); IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, Genoa, Italy (M.I., C.L.); Center for Neurologic Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.M., A.M.P., C.R.G.G.); Department of Radiology and Nuclear Medicine, MS Center Amsterdam, Amsterdam Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (B.M.); Department of Epidemiology and Data Science, Amsterdam University Medical Center, Amsterdam, the Netherlands (J.W.R.T.); Anatomy & Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (L.E.J.); and Amsterdam Neuroscience, Brain Imaging and Neurodegeneration, Amsterdam, the Netherlands (L.E.J.)., Beck ES; From the MS Center Amsterdam, Anatomy & Neurosciences, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands (P.M.B., S.N., F.A.N.S., M.M.S., J.J.G.G., M.D.S.); Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Md (E.S.B., D.S.R.); Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY (E.S.B.); Bio-imaging Institute, University of Bordeaux, Bordeaux, France (G.B.); Neurology Section, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy (M. Castellaro, M. Calabrese); Department of Information Engineering, University of Padova, Padova, Italy (M. Castellaro); NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK (D.T.C.); National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK (D.T.C.); Departments of Neuroradiology (P.E., B.W.) and Neurology (M.M.), School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; Neuroimaging Research Unit, Division of Neuroscience Neurology Unit, IRCCS San Raffaele Scientific Institute Vita-Salute San Raffaele University, Milan, Italy (M.F., P.P., M.A.R.); Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genoa, Italy (M.I., C.L.); IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, Genoa, Italy (M.I., C.L.); Center for Neurologic Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.M., A.M.P., C.R.G.G.); Department of Radiology and Nuclear Medicine, MS Center Amsterdam, Amsterdam Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (B.M.); Department of Epidemiology and Data Science, Amsterdam University Medical Center, Amsterdam, the Netherlands (J.W.R.T.); Anatomy & Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (L.E.J.); and Amsterdam Neuroscience, Brain Imaging and Neurodegeneration, Amsterdam, the Netherlands (L.E.J.)., Bliault G; From the MS Center Amsterdam, Anatomy & Neurosciences, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands (P.M.B., S.N., F.A.N.S., M.M.S., J.J.G.G., M.D.S.); Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Md (E.S.B., D.S.R.); Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY (E.S.B.); Bio-imaging Institute, University of Bordeaux, Bordeaux, France (G.B.); Neurology Section, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy (M. Castellaro, M. Calabrese); Department of Information Engineering, University of Padova, Padova, Italy (M. Castellaro); NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK (D.T.C.); National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK (D.T.C.); Departments of Neuroradiology (P.E., B.W.) and Neurology (M.M.), School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; Neuroimaging Research Unit, Division of Neuroscience Neurology Unit, IRCCS San Raffaele Scientific Institute Vita-Salute San Raffaele University, Milan, Italy (M.F., P.P., M.A.R.); Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genoa, Italy (M.I., C.L.); IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, Genoa, Italy (M.I., C.L.); Center for Neurologic Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.M., A.M.P., C.R.G.G.); Department of Radiology and Nuclear Medicine, MS Center Amsterdam, Amsterdam Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (B.M.); Department of Epidemiology and Data Science, Amsterdam University Medical Center, Amsterdam, the Netherlands (J.W.R.T.); Anatomy & Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (L.E.J.); and Amsterdam Neuroscience, Brain Imaging and Neurodegeneration, Amsterdam, the Netherlands (L.E.J.)., Castellaro M; From the MS Center Amsterdam, Anatomy & Neurosciences, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands (P.M.B., S.N., F.A.N.S., M.M.S., J.J.G.G., M.D.S.); Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Md (E.S.B., D.S.R.); Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY (E.S.B.); Bio-imaging Institute, University of Bordeaux, Bordeaux, France (G.B.); Neurology Section, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy (M. Castellaro, M. Calabrese); Department of Information Engineering, University of Padova, Padova, Italy (M. Castellaro); NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK (D.T.C.); National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK (D.T.C.); Departments of Neuroradiology (P.E., B.W.) and Neurology (M.M.), School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; Neuroimaging Research Unit, Division of Neuroscience Neurology Unit, IRCCS San Raffaele Scientific Institute Vita-Salute San Raffaele University, Milan, Italy (M.F., P.P., M.A.R.); Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genoa, Italy (M.I., C.L.); IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, Genoa, Italy (M.I., C.L.); Center for Neurologic Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.M., A.M.P., C.R.G.G.); Department of Radiology and Nuclear Medicine, MS Center Amsterdam, Amsterdam Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (B.M.); Department of Epidemiology and Data Science, Amsterdam University Medical Center, Amsterdam, the Netherlands (J.W.R.T.); Anatomy & Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (L.E.J.); and Amsterdam Neuroscience, Brain Imaging and Neurodegeneration, Amsterdam, the Netherlands (L.E.J.)., Calabrese M; From the MS Center Amsterdam, Anatomy & Neurosciences, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands (P.M.B., S.N., F.A.N.S., M.M.S., J.J.G.G., M.D.S.); Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Md (E.S.B., D.S.R.); Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY (E.S.B.); Bio-imaging Institute, University of Bordeaux, Bordeaux, France (G.B.); Neurology Section, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy (M. Castellaro, M. Calabrese); Department of Information Engineering, University of Padova, Padova, Italy (M. Castellaro); NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK (D.T.C.); National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK (D.T.C.); Departments of Neuroradiology (P.E., B.W.) and Neurology (M.M.), School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; Neuroimaging Research Unit, Division of Neuroscience Neurology Unit, IRCCS San Raffaele Scientific Institute Vita-Salute San Raffaele University, Milan, Italy (M.F., P.P., M.A.R.); Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genoa, Italy (M.I., C.L.); IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, Genoa, Italy (M.I., C.L.); Center for Neurologic Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.M., A.M.P., C.R.G.G.); Department of Radiology and Nuclear Medicine, MS Center Amsterdam, Amsterdam Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (B.M.); Department of Epidemiology and Data Science, Amsterdam University Medical Center, Amsterdam, the Netherlands (J.W.R.T.); Anatomy & Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (L.E.J.); and Amsterdam Neuroscience, Brain Imaging and Neurodegeneration, Amsterdam, the Netherlands (L.E.J.)., Chard DT; From the MS Center Amsterdam, Anatomy & Neurosciences, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands (P.M.B., S.N., F.A.N.S., M.M.S., J.J.G.G., M.D.S.); Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Md (E.S.B., D.S.R.); Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY (E.S.B.); Bio-imaging Institute, University of Bordeaux, Bordeaux, France (G.B.); Neurology Section, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy (M. Castellaro, M. Calabrese); Department of Information Engineering, University of Padova, Padova, Italy (M. Castellaro); NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK (D.T.C.); National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK (D.T.C.); Departments of Neuroradiology (P.E., B.W.) and Neurology (M.M.), School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; Neuroimaging Research Unit, Division of Neuroscience Neurology Unit, IRCCS San Raffaele Scientific Institute Vita-Salute San Raffaele University, Milan, Italy (M.F., P.P., M.A.R.); Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genoa, Italy (M.I., C.L.); IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, Genoa, Italy (M.I., C.L.); Center for Neurologic Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.M., A.M.P., C.R.G.G.); Department of Radiology and Nuclear Medicine, MS Center Amsterdam, Amsterdam Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (B.M.); Department of Epidemiology and Data Science, Amsterdam University Medical Center, Amsterdam, the Netherlands (J.W.R.T.); Anatomy & Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (L.E.J.); and Amsterdam Neuroscience, Brain Imaging and Neurodegeneration, Amsterdam, the Netherlands (L.E.J.)., Eichinger P; From the MS Center Amsterdam, Anatomy & Neurosciences, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands (P.M.B., S.N., F.A.N.S., M.M.S., J.J.G.G., M.D.S.); Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Md (E.S.B., D.S.R.); Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY (E.S.B.); Bio-imaging Institute, University of Bordeaux, Bordeaux, France (G.B.); Neurology Section, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy (M. Castellaro, M. Calabrese); Department of Information Engineering, University of Padova, Padova, Italy (M. Castellaro); NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK (D.T.C.); National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK (D.T.C.); Departments of Neuroradiology (P.E., B.W.) and Neurology (M.M.), School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; Neuroimaging Research Unit, Division of Neuroscience Neurology Unit, IRCCS San Raffaele Scientific Institute Vita-Salute San Raffaele University, Milan, Italy (M.F., P.P., M.A.R.); Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genoa, Italy (M.I., C.L.); IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, Genoa, Italy (M.I., C.L.); Center for Neurologic Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.M., A.M.P., C.R.G.G.); Department of Radiology and Nuclear Medicine, MS Center Amsterdam, Amsterdam Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (B.M.); Department of Epidemiology and Data Science, Amsterdam University Medical Center, Amsterdam, the Netherlands (J.W.R.T.); Anatomy & Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (L.E.J.); and Amsterdam Neuroscience, Brain Imaging and Neurodegeneration, Amsterdam, the Netherlands (L.E.J.)., Filippi M; From the MS Center Amsterdam, Anatomy & Neurosciences, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands (P.M.B., S.N., F.A.N.S., M.M.S., J.J.G.G., M.D.S.); Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Md (E.S.B., D.S.R.); Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY (E.S.B.); Bio-imaging Institute, University of Bordeaux, Bordeaux, France (G.B.); Neurology Section, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy (M. Castellaro, M. Calabrese); Department of Information Engineering, University of Padova, Padova, Italy (M. Castellaro); NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK (D.T.C.); National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK (D.T.C.); Departments of Neuroradiology (P.E., B.W.) and Neurology (M.M.), School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; Neuroimaging Research Unit, Division of Neuroscience Neurology Unit, IRCCS San Raffaele Scientific Institute Vita-Salute San Raffaele University, Milan, Italy (M.F., P.P., M.A.R.); Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genoa, Italy (M.I., C.L.); IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, Genoa, Italy (M.I., C.L.); Center for Neurologic Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.M., A.M.P., C.R.G.G.); Department of Radiology and Nuclear Medicine, MS Center Amsterdam, Amsterdam Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (B.M.); Department of Epidemiology and Data Science, Amsterdam University Medical Center, Amsterdam, the Netherlands (J.W.R.T.); Anatomy & Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (L.E.J.); and Amsterdam Neuroscience, Brain Imaging and Neurodegeneration, Amsterdam, the Netherlands (L.E.J.)., Inglese M; From the MS Center Amsterdam, Anatomy & Neurosciences, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands (P.M.B., S.N., F.A.N.S., M.M.S., J.J.G.G., M.D.S.); Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Md (E.S.B., D.S.R.); Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY (E.S.B.); Bio-imaging Institute, University of Bordeaux, Bordeaux, France (G.B.); Neurology Section, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy (M. Castellaro, M. Calabrese); Department of Information Engineering, University of Padova, Padova, Italy (M. Castellaro); NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK (D.T.C.); National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK (D.T.C.); Departments of Neuroradiology (P.E., B.W.) and Neurology (M.M.), School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; Neuroimaging Research Unit, Division of Neuroscience Neurology Unit, IRCCS San Raffaele Scientific Institute Vita-Salute San Raffaele University, Milan, Italy (M.F., P.P., M.A.R.); Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genoa, Italy (M.I., C.L.); IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, Genoa, Italy (M.I., C.L.); Center for Neurologic Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.M., A.M.P., C.R.G.G.); Department of Radiology and Nuclear Medicine, MS Center Amsterdam, Amsterdam Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (B.M.); Department of Epidemiology and Data Science, Amsterdam University Medical Center, Amsterdam, the Netherlands (J.W.R.T.); Anatomy & Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (L.E.J.); and Amsterdam Neuroscience, Brain Imaging and Neurodegeneration, Amsterdam, the Netherlands (L.E.J.)., Lapucci C; From the MS Center Amsterdam, Anatomy & Neurosciences, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands (P.M.B., S.N., F.A.N.S., M.M.S., J.J.G.G., M.D.S.); Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Md (E.S.B., D.S.R.); Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY (E.S.B.); Bio-imaging Institute, University of Bordeaux, Bordeaux, France (G.B.); Neurology Section, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy (M. Castellaro, M. Calabrese); Department of Information Engineering, University of Padova, Padova, Italy (M. Castellaro); NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK (D.T.C.); National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK (D.T.C.); Departments of Neuroradiology (P.E., B.W.) and Neurology (M.M.), School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; Neuroimaging Research Unit, Division of Neuroscience Neurology Unit, IRCCS San Raffaele Scientific Institute Vita-Salute San Raffaele University, Milan, Italy (M.F., P.P., M.A.R.); Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genoa, Italy (M.I., C.L.); IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, Genoa, Italy (M.I., C.L.); Center for Neurologic Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.M., A.M.P., C.R.G.G.); Department of Radiology and Nuclear Medicine, MS Center Amsterdam, Amsterdam Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (B.M.); Department of Epidemiology and Data Science, Amsterdam University Medical Center, Amsterdam, the Netherlands (J.W.R.T.); Anatomy & Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (L.E.J.); and Amsterdam Neuroscience, Brain Imaging and Neurodegeneration, Amsterdam, the Netherlands (L.E.J.)., Marciniak A; From the MS Center Amsterdam, Anatomy & Neurosciences, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands (P.M.B., S.N., F.A.N.S., M.M.S., J.J.G.G., M.D.S.); Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Md (E.S.B., D.S.R.); Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY (E.S.B.); Bio-imaging Institute, University of Bordeaux, Bordeaux, France (G.B.); Neurology Section, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy (M. Castellaro, M. Calabrese); Department of Information Engineering, University of Padova, Padova, Italy (M. Castellaro); NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK (D.T.C.); National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK (D.T.C.); Departments of Neuroradiology (P.E., B.W.) and Neurology (M.M.), School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; Neuroimaging Research Unit, Division of Neuroscience Neurology Unit, IRCCS San Raffaele Scientific Institute Vita-Salute San Raffaele University, Milan, Italy (M.F., P.P., M.A.R.); Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genoa, Italy (M.I., C.L.); IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, Genoa, Italy (M.I., C.L.); Center for Neurologic Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.M., A.M.P., C.R.G.G.); Department of Radiology and Nuclear Medicine, MS Center Amsterdam, Amsterdam Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (B.M.); Department of Epidemiology and Data Science, Amsterdam University Medical Center, Amsterdam, the Netherlands (J.W.R.T.); Anatomy & Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (L.E.J.); and Amsterdam Neuroscience, Brain Imaging and Neurodegeneration, Amsterdam, the Netherlands (L.E.J.)., Moraal B; From the MS Center Amsterdam, Anatomy & Neurosciences, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands (P.M.B., S.N., F.A.N.S., M.M.S., J.J.G.G., M.D.S.); Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Md (E.S.B., D.S.R.); Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY (E.S.B.); Bio-imaging Institute, University of Bordeaux, Bordeaux, France (G.B.); Neurology Section, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy (M. Castellaro, M. Calabrese); Department of Information Engineering, University of Padova, Padova, Italy (M. Castellaro); NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK (D.T.C.); National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK (D.T.C.); Departments of Neuroradiology (P.E., B.W.) and Neurology (M.M.), School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; Neuroimaging Research Unit, Division of Neuroscience Neurology Unit, IRCCS San Raffaele Scientific Institute Vita-Salute San Raffaele University, Milan, Italy (M.F., P.P., M.A.R.); Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genoa, Italy (M.I., C.L.); IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, Genoa, Italy (M.I., C.L.); Center for Neurologic Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.M., A.M.P., C.R.G.G.); Department of Radiology and Nuclear Medicine, MS Center Amsterdam, Amsterdam Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (B.M.); Department of Epidemiology and Data Science, Amsterdam University Medical Center, Amsterdam, the Netherlands (J.W.R.T.); Anatomy & Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (L.E.J.); and Amsterdam Neuroscience, Brain Imaging and Neurodegeneration, Amsterdam, the Netherlands (L.E.J.)., Morales Pinzon A; From the MS Center Amsterdam, Anatomy & Neurosciences, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands (P.M.B., S.N., F.A.N.S., M.M.S., J.J.G.G., M.D.S.); Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Md (E.S.B., D.S.R.); Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY (E.S.B.); Bio-imaging Institute, University of Bordeaux, Bordeaux, France (G.B.); Neurology Section, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy (M. Castellaro, M. Calabrese); Department of Information Engineering, University of Padova, Padova, Italy (M. Castellaro); NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK (D.T.C.); National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK (D.T.C.); Departments of Neuroradiology (P.E., B.W.) and Neurology (M.M.), School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; Neuroimaging Research Unit, Division of Neuroscience Neurology Unit, IRCCS San Raffaele Scientific Institute Vita-Salute San Raffaele University, Milan, Italy (M.F., P.P., M.A.R.); Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genoa, Italy (M.I., C.L.); IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, Genoa, Italy (M.I., C.L.); Center for Neurologic Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.M., A.M.P., C.R.G.G.); Department of Radiology and Nuclear Medicine, MS Center Amsterdam, Amsterdam Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (B.M.); Department of Epidemiology and Data Science, Amsterdam University Medical Center, Amsterdam, the Netherlands (J.W.R.T.); Anatomy & Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (L.E.J.); and Amsterdam Neuroscience, Brain Imaging and Neurodegeneration, Amsterdam, the Netherlands (L.E.J.)., Mühlau M; From the MS Center Amsterdam, Anatomy & Neurosciences, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands (P.M.B., S.N., F.A.N.S., M.M.S., J.J.G.G., M.D.S.); Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Md (E.S.B., D.S.R.); Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY (E.S.B.); Bio-imaging Institute, University of Bordeaux, Bordeaux, France (G.B.); Neurology Section, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy (M. Castellaro, M. Calabrese); Department of Information Engineering, University of Padova, Padova, Italy (M. Castellaro); NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK (D.T.C.); National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK (D.T.C.); Departments of Neuroradiology (P.E., B.W.) and Neurology (M.M.), School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; Neuroimaging Research Unit, Division of Neuroscience Neurology Unit, IRCCS San Raffaele Scientific Institute Vita-Salute San Raffaele University, Milan, Italy (M.F., P.P., M.A.R.); Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genoa, Italy (M.I., C.L.); IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, Genoa, Italy (M.I., C.L.); Center for Neurologic Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.M., A.M.P., C.R.G.G.); Department of Radiology and Nuclear Medicine, MS Center Amsterdam, Amsterdam Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (B.M.); Department of Epidemiology and Data Science, Amsterdam University Medical Center, Amsterdam, the Netherlands (J.W.R.T.); Anatomy & Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (L.E.J.); and Amsterdam Neuroscience, Brain Imaging and Neurodegeneration, Amsterdam, the Netherlands (L.E.J.)., Preziosa P; From the MS Center Amsterdam, Anatomy & Neurosciences, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands (P.M.B., S.N., F.A.N.S., M.M.S., J.J.G.G., M.D.S.); Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Md (E.S.B., D.S.R.); Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY (E.S.B.); Bio-imaging Institute, University of Bordeaux, Bordeaux, France (G.B.); Neurology Section, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy (M. Castellaro, M. Calabrese); Department of Information Engineering, University of Padova, Padova, Italy (M. Castellaro); NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK (D.T.C.); National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK (D.T.C.); Departments of Neuroradiology (P.E., B.W.) and Neurology (M.M.), School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; Neuroimaging Research Unit, Division of Neuroscience Neurology Unit, IRCCS San Raffaele Scientific Institute Vita-Salute San Raffaele University, Milan, Italy (M.F., P.P., M.A.R.); Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genoa, Italy (M.I., C.L.); IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, Genoa, Italy (M.I., C.L.); Center for Neurologic Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.M., A.M.P., C.R.G.G.); Department of Radiology and Nuclear Medicine, MS Center Amsterdam, Amsterdam Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (B.M.); Department of Epidemiology and Data Science, Amsterdam University Medical Center, Amsterdam, the Netherlands (J.W.R.T.); Anatomy & Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (L.E.J.); and Amsterdam Neuroscience, Brain Imaging and Neurodegeneration, Amsterdam, the Netherlands (L.E.J.)., Reich DS; From the MS Center Amsterdam, Anatomy & Neurosciences, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands (P.M.B., S.N., F.A.N.S., M.M.S., J.J.G.G., M.D.S.); Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Md (E.S.B., D.S.R.); Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY (E.S.B.); Bio-imaging Institute, University of Bordeaux, Bordeaux, France (G.B.); Neurology Section, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy (M. Castellaro, M. Calabrese); Department of Information Engineering, University of Padova, Padova, Italy (M. Castellaro); NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK (D.T.C.); National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK (D.T.C.); Departments of Neuroradiology (P.E., B.W.) and Neurology (M.M.), School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; Neuroimaging Research Unit, Division of Neuroscience Neurology Unit, IRCCS San Raffaele Scientific Institute Vita-Salute San Raffaele University, Milan, Italy (M.F., P.P., M.A.R.); Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genoa, Italy (M.I., C.L.); IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, Genoa, Italy (M.I., C.L.); Center for Neurologic Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.M., A.M.P., C.R.G.G.); Department of Radiology and Nuclear Medicine, MS Center Amsterdam, Amsterdam Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (B.M.); Department of Epidemiology and Data Science, Amsterdam University Medical Center, Amsterdam, the Netherlands (J.W.R.T.); Anatomy & Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (L.E.J.); and Amsterdam Neuroscience, Brain Imaging and Neurodegeneration, Amsterdam, the Netherlands (L.E.J.)., Rocca MA; From the MS Center Amsterdam, Anatomy & Neurosciences, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands (P.M.B., S.N., F.A.N.S., M.M.S., J.J.G.G., M.D.S.); Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Md (E.S.B., D.S.R.); Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY (E.S.B.); Bio-imaging Institute, University of Bordeaux, Bordeaux, France (G.B.); Neurology Section, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy (M. Castellaro, M. Calabrese); Department of Information Engineering, University of Padova, Padova, Italy (M. Castellaro); NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK (D.T.C.); National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK (D.T.C.); Departments of Neuroradiology (P.E., B.W.) and Neurology (M.M.), School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; Neuroimaging Research Unit, Division of Neuroscience Neurology Unit, IRCCS San Raffaele Scientific Institute Vita-Salute San Raffaele University, Milan, Italy (M.F., P.P., M.A.R.); Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genoa, Italy (M.I., C.L.); IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, Genoa, Italy (M.I., C.L.); Center for Neurologic Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.M., A.M.P., C.R.G.G.); Department of Radiology and Nuclear Medicine, MS Center Amsterdam, Amsterdam Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (B.M.); Department of Epidemiology and Data Science, Amsterdam University Medical Center, Amsterdam, the Netherlands (J.W.R.T.); Anatomy & Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (L.E.J.); and Amsterdam Neuroscience, Brain Imaging and Neurodegeneration, Amsterdam, the Netherlands (L.E.J.)., Schoonheim MM; From the MS Center Amsterdam, Anatomy & Neurosciences, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands (P.M.B., S.N., F.A.N.S., M.M.S., J.J.G.G., M.D.S.); Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Md (E.S.B., D.S.R.); Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY (E.S.B.); Bio-imaging Institute, University of Bordeaux, Bordeaux, France (G.B.); Neurology Section, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy (M. Castellaro, M. Calabrese); Department of Information Engineering, University of Padova, Padova, Italy (M. Castellaro); NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK (D.T.C.); National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK (D.T.C.); Departments of Neuroradiology (P.E., B.W.) and Neurology (M.M.), School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; Neuroimaging Research Unit, Division of Neuroscience Neurology Unit, IRCCS San Raffaele Scientific Institute Vita-Salute San Raffaele University, Milan, Italy (M.F., P.P., M.A.R.); Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genoa, Italy (M.I., C.L.); IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, Genoa, Italy (M.I., C.L.); Center for Neurologic Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.M., A.M.P., C.R.G.G.); Department of Radiology and Nuclear Medicine, MS Center Amsterdam, Amsterdam Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (B.M.); Department of Epidemiology and Data Science, Amsterdam University Medical Center, Amsterdam, the Netherlands (J.W.R.T.); Anatomy & Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (L.E.J.); and Amsterdam Neuroscience, Brain Imaging and Neurodegeneration, Amsterdam, the Netherlands (L.E.J.)., Twisk JWR; From the MS Center Amsterdam, Anatomy & Neurosciences, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands (P.M.B., S.N., F.A.N.S., M.M.S., J.J.G.G., M.D.S.); Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Md (E.S.B., D.S.R.); Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY (E.S.B.); Bio-imaging Institute, University of Bordeaux, Bordeaux, France (G.B.); Neurology Section, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy (M. Castellaro, M. Calabrese); Department of Information Engineering, University of Padova, Padova, Italy (M. Castellaro); NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK (D.T.C.); National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK (D.T.C.); Departments of Neuroradiology (P.E., B.W.) and Neurology (M.M.), School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; Neuroimaging Research Unit, Division of Neuroscience Neurology Unit, IRCCS San Raffaele Scientific Institute Vita-Salute San Raffaele University, Milan, Italy (M.F., P.P., M.A.R.); Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genoa, Italy (M.I., C.L.); IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, Genoa, Italy (M.I., C.L.); Center for Neurologic Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.M., A.M.P., C.R.G.G.); Department of Radiology and Nuclear Medicine, MS Center Amsterdam, Amsterdam Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (B.M.); Department of Epidemiology and Data Science, Amsterdam University Medical Center, Amsterdam, the Netherlands (J.W.R.T.); Anatomy & Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (L.E.J.); and Amsterdam Neuroscience, Brain Imaging and Neurodegeneration, Amsterdam, the Netherlands (L.E.J.)., Wiestler B; From the MS Center Amsterdam, Anatomy & Neurosciences, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands (P.M.B., S.N., F.A.N.S., M.M.S., J.J.G.G., M.D.S.); Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Md (E.S.B., D.S.R.); Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY (E.S.B.); Bio-imaging Institute, University of Bordeaux, Bordeaux, France (G.B.); Neurology Section, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy (M. Castellaro, M. Calabrese); Department of Information Engineering, University of Padova, Padova, Italy (M. Castellaro); NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK (D.T.C.); National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK (D.T.C.); Departments of Neuroradiology (P.E., B.W.) and Neurology (M.M.), School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; Neuroimaging Research Unit, Division of Neuroscience Neurology Unit, IRCCS San Raffaele Scientific Institute Vita-Salute San Raffaele University, Milan, Italy (M.F., P.P., M.A.R.); Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genoa, Italy (M.I., C.L.); IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, Genoa, Italy (M.I., C.L.); Center for Neurologic Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.M., A.M.P., C.R.G.G.); Department of Radiology and Nuclear Medicine, MS Center Amsterdam, Amsterdam Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (B.M.); Department of Epidemiology and Data Science, Amsterdam University Medical Center, Amsterdam, the Netherlands (J.W.R.T.); Anatomy & Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (L.E.J.); and Amsterdam Neuroscience, Brain Imaging and Neurodegeneration, Amsterdam, the Netherlands (L.E.J.)., Jonkman LE; From the MS Center Amsterdam, Anatomy & Neurosciences, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands (P.M.B., S.N., F.A.N.S., M.M.S., J.J.G.G., M.D.S.); Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Md (E.S.B., D.S.R.); Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY (E.S.B.); Bio-imaging Institute, University of Bordeaux, Bordeaux, France (G.B.); Neurology Section, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy (M. Castellaro, M. Calabrese); Department of Information Engineering, University of Padova, Padova, Italy (M. Castellaro); NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK (D.T.C.); National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK (D.T.C.); Departments of Neuroradiology (P.E., B.W.) and Neurology (M.M.), School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; Neuroimaging Research Unit, Division of Neuroscience Neurology Unit, IRCCS San Raffaele Scientific Institute Vita-Salute San Raffaele University, Milan, Italy (M.F., P.P., M.A.R.); Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genoa, Italy (M.I., C.L.); IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, Genoa, Italy (M.I., C.L.); Center for Neurologic Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.M., A.M.P., C.R.G.G.); Department of Radiology and Nuclear Medicine, MS Center Amsterdam, Amsterdam Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (B.M.); Department of Epidemiology and Data Science, Amsterdam University Medical Center, Amsterdam, the Netherlands (J.W.R.T.); Anatomy & Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (L.E.J.); and Amsterdam Neuroscience, Brain Imaging and Neurodegeneration, Amsterdam, the Netherlands (L.E.J.)., Guttmann CRG; From the MS Center Amsterdam, Anatomy & Neurosciences, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands (P.M.B., S.N., F.A.N.S., M.M.S., J.J.G.G., M.D.S.); Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Md (E.S.B., D.S.R.); Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY (E.S.B.); Bio-imaging Institute, University of Bordeaux, Bordeaux, France (G.B.); Neurology Section, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy (M. Castellaro, M. Calabrese); Department of Information Engineering, University of Padova, Padova, Italy (M. Castellaro); NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK (D.T.C.); National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK (D.T.C.); Departments of Neuroradiology (P.E., B.W.) and Neurology (M.M.), School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; Neuroimaging Research Unit, Division of Neuroscience Neurology Unit, IRCCS San Raffaele Scientific Institute Vita-Salute San Raffaele University, Milan, Italy (M.F., P.P., M.A.R.); Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genoa, Italy (M.I., C.L.); IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, Genoa, Italy (M.I., C.L.); Center for Neurologic Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.M., A.M.P., C.R.G.G.); Department of Radiology and Nuclear Medicine, MS Center Amsterdam, Amsterdam Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (B.M.); Department of Epidemiology and Data Science, Amsterdam University Medical Center, Amsterdam, the Netherlands (J.W.R.T.); Anatomy & Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (L.E.J.); and Amsterdam Neuroscience, Brain Imaging and Neurodegeneration, Amsterdam, the Netherlands (L.E.J.)., Geurts JJG; From the MS Center Amsterdam, Anatomy & Neurosciences, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands (P.M.B., S.N., F.A.N.S., M.M.S., J.J.G.G., M.D.S.); Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Md (E.S.B., D.S.R.); Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY (E.S.B.); Bio-imaging Institute, University of Bordeaux, Bordeaux, France (G.B.); Neurology Section, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy (M. Castellaro, M. Calabrese); Department of Information Engineering, University of Padova, Padova, Italy (M. Castellaro); NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK (D.T.C.); National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK (D.T.C.); Departments of Neuroradiology (P.E., B.W.) and Neurology (M.M.), School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; Neuroimaging Research Unit, Division of Neuroscience Neurology Unit, IRCCS San Raffaele Scientific Institute Vita-Salute San Raffaele University, Milan, Italy (M.F., P.P., M.A.R.); Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genoa, Italy (M.I., C.L.); IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, Genoa, Italy (M.I., C.L.); Center for Neurologic Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.M., A.M.P., C.R.G.G.); Department of Radiology and Nuclear Medicine, MS Center Amsterdam, Amsterdam Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (B.M.); Department of Epidemiology and Data Science, Amsterdam University Medical Center, Amsterdam, the Netherlands (J.W.R.T.); Anatomy & Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (L.E.J.); and Amsterdam Neuroscience, Brain Imaging and Neurodegeneration, Amsterdam, the Netherlands (L.E.J.)., Steenwijk MD; From the MS Center Amsterdam, Anatomy & Neurosciences, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, De Boelelaan 1117, Amsterdam, the Netherlands (P.M.B., S.N., F.A.N.S., M.M.S., J.J.G.G., M.D.S.); Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, Md (E.S.B., D.S.R.); Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY (E.S.B.); Bio-imaging Institute, University of Bordeaux, Bordeaux, France (G.B.); Neurology Section, Department of Neuroscience, Biomedicine and Movement Sciences, University of Verona, Verona, Italy (M. Castellaro, M. Calabrese); Department of Information Engineering, University of Padova, Padova, Italy (M. Castellaro); NMR Research Unit, Queen Square MS Centre, Department of Neuroinflammation, UCL Queen Square Institute of Neurology, Faculty of Brain Sciences, University College London, London, UK (D.T.C.); National Institute for Health Research University College London Hospitals Biomedical Research Centre, London, UK (D.T.C.); Departments of Neuroradiology (P.E., B.W.) and Neurology (M.M.), School of Medicine, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany; Neuroimaging Research Unit, Division of Neuroscience Neurology Unit, IRCCS San Raffaele Scientific Institute Vita-Salute San Raffaele University, Milan, Italy (M.F., P.P., M.A.R.); Department of Neuroscience, Rehabilitation, Ophthalmology, Genetics, Maternal and Child Health, University of Genova, Genoa, Italy (M.I., C.L.); IRCCS Ospedale Policlinico San Martino, Largo Rosanna Benzi, Genoa, Italy (M.I., C.L.); Center for Neurologic Imaging, Department of Radiology, Brigham and Women's Hospital, Harvard Medical School, Boston, Mass (A.M., A.M.P., C.R.G.G.); Department of Radiology and Nuclear Medicine, MS Center Amsterdam, Amsterdam Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (B.M.); Department of Epidemiology and Data Science, Amsterdam University Medical Center, Amsterdam, the Netherlands (J.W.R.T.); Anatomy & Neurosciences, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands (L.E.J.); and Amsterdam Neuroscience, Brain Imaging and Neurodegeneration, Amsterdam, the Netherlands (L.E.J.).

المصدر: Radiology [Radiology] 2023 Apr; Vol. 307 (2), pp. e221425. Date of Electronic Publication: 2023 Feb 07.

نوع المنشور: Multicenter Study; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Radiological Society of North America Country of Publication: United States NLM ID: 0401260 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1527-1315 (Electronic) Linking ISSN: 00338419 NLM ISO Abbreviation: Radiology Subsets: MEDLINE

مواضيع طبية MeSH: Multiple Sclerosis*/diagnostic imaging , Multiple Sclerosis*/pathology, Humans ; Female ; Middle Aged ; Artificial Intelligence ; Retrospective Studies ; Reproducibility of Results ; Magnetic Resonance Imaging/methods

المؤلفون: Okar SV; Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, United States., Hu F; Department of Biostatistics, Epidemiology, and Informatics, Penn Statistics in Imaging and Visualization Center, University of Pennsylvania, Philadelphia, PA, United States., Shinohara RT; Department of Biostatistics, Epidemiology, and Informatics, Penn Statistics in Imaging and Visualization Center, University of Pennsylvania, Philadelphia, PA, United States., Beck ES; Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, United States.; Department of Neurology, Icahn School of Medicine at Mount Sinai, New York, NY, United States., Reich DS; Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, United States., Ineichen BV; Translational Neuroradiology Section, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, United States.; Department of Neuroradiology, Clinical Neuroscience Center, University Hospital Zurich, University of Zurich, Zurich, Switzerland.; Center for Reproducible Science, University of Zurich, Zurich, Switzerland.

المصدر: Frontiers in neuroscience [Front Neurosci] 2023 Mar 30; Vol. 17, pp. 1038011. Date of Electronic Publication: 2023 Mar 30 (Print Publication: 2023).

نوع المنشور: Systematic Review

بيانات الدورية: Publisher: Frontiers Research Foundation Country of Publication: Switzerland NLM ID: 101478481 Publication Model: eCollection Cited Medium: Print ISSN: 1662-4548 (Print) Linking ISSN: 1662453X NLM ISO Abbreviation: Front Neurosci Subsets: PubMed not MEDLINE