المؤلفون: Lea Landolt, Jessica Furriol, Janka Babickova, Lavina Ahmed, Øystein Eikrem, Trude Skogstrand, Andreas Scherer, Salwa Suliman, Sabine Leh, James B. Lorens, Gro Gausdal, Hans‐Peter Marti, Tarig Osman

المصدر: Physiological Reports, Vol 7, Iss 10, Pp n/a-n/a (2019)

مصطلحات موضوعية: AXL targeting, Bemcentinib (BGB324), renal fibrosis, UUO, Physiology, QP1-981

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2051-817X

URL الوصول: https://doaj.org/article/ba28f9a6ff404566a3999026d8de02a5

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المؤلفون: Montserrat Marí, Anna Tutusaus, Cristina Aresté, Estefanía de Gregorio, Mar Coll, Albert Morales, James B. Lorens, Pablo García de Frutos, Gro Gausdal, Anna Colell, Blanca Cucarull, Isabel Graupera, Helena Cristóbal

المساهمون: Instituto de Salud Carlos III, Centro de Investigación Biomédica en Red Enfermedades Hepáticas y Digestivas (España), Ministerio de Economía y Competitividad (España), Ministerio de Ciencia, Innovación y Universidades (España), Agencia Estatal de Investigación (España), European Commission, Fundació La Marató de TV3, Generalitat de Catalunya

المصدر: Digital.CSIC. Repositorio Institucional del CSIC
instname
Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology (CMGH)
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 3, Pp 349-368 (2020)

مصطلحات موضوعية: 0301 basic medicine, Liver Cirrhosis, Male, medicine.medical_treatment, Biopsy, Bemcentinib (BGB324), GAS6/TAM Signaling, Mice, 0302 clinical medicine, Fibrosis, Non-alcoholic Fatty Liver Disease, Medicine, Cells, Cultured, Mice, Knockout, Gastroenterology, Middle Aged, Benzocycloheptenes, Cytokine, Editorial, Lipotoxicity, Liver, Disease Progression, Intercellular Signaling Peptides and Proteins, Liver Fibrosis, 030211 gastroenterology & hepatology, Female, Signal Transduction, Adult, STAT3 Transcription Factor, AXL Inhibitor BGB324, Kupffer Cells, Primary Cell Culture, 03 medical and health sciences, Proto-Oncogene Proteins, Hepatic Stellate Cells, Animals, Humans, lcsh:RC799-869, Aged, Hepatology, c-Mer Tyrosine Kinase, business.industry, GAS6, Receptor Protein-Tyrosine Kinases, nutritional and metabolic diseases, MERTK, Triazoles, medicine.disease, Axl Receptor Tyrosine Kinase, Disease Models, Animal, 030104 developmental biology, Cancer research, Hepatic stellate cell, Hepatocytes, lcsh:Diseases of the digestive system. Gastroenterology, Steatohepatitis, business, Proto-Oncogene Proteins c-akt, Biomarkers, Liver Inflammation

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abd0af491353a59385b69d42035b9ec9
http://hdl.handle.net/10261/223520

المؤلفون: Francisco Javier Cubero

المصدر: Cellular and Molecular Gastroenterology and Hepatology
Cellular and Molecular Gastroenterology and Hepatology, Vol 9, Iss 3, Pp 545-546 (2020)

مصطلحات موضوعية: Oncology, Bemcentinib (BGB324), ADAM17, a disintegrin and metalloproteinase 17, MPO, myeloperoxidase, GAS6/TAM Signaling, Non-alcoholic Fatty Liver Disease, Medicine, MMP9, matrix metalloproteinase-9, Original Research, TNF, tumor necrosis factor, NAS, NAFLD activity score, Gastroenterology, ELISA, enzyme-linked immunosorbent assay, MCP-1, monocyte chemoattractant protein-1, sMERTK, soluble MERTK, HSC, hepatic stellate cell, mRNA, messenger RNA, ECM, extracellular matrix, Disease Progression, Liver Fibrosis, LPS, lipopolysaccharide, NASH, nonalcoholic steatohepatitis, Signal Transduction, medicine.medical_specialty, sAXL, soluble AXL, MEDLINE, PBS, phosphate-buffered saline, TAM, Tyro3-Axl-Mertk, HFD, high-fat choline-deficient methionine-restricted diet, cDNA, complementary DNA, PA, palmitic acid, MCD, methionine-choline-deficient diet, Internal medicine, Hepatic Stellate Cells, Humans, KC, Kupffer cell, lcsh:RC799-869, KO, knockout, Hepatology, business.industry, Disease progression, nutritional and metabolic diseases, GAS6, Growth arrest-specific gene 6, WT, wild-type, IL, interleukin, ADAM10, a disintegrin and metalloproteinase 10, H&E, hematoxylin and eosin, lcsh:Diseases of the digestive system. Gastroenterology, NAFLD, nonalcoholic fatty liver disease, business, HCC, hepatocellular carcinoma, Value (mathematics), PMH, primary mouse hepatocyte, Liver Inflammation

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d4447636c8bfbf18ac86d901acecbc4e
https://pubmed.ncbi.nlm.nih.gov/31689560

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المؤلفون: Andreas Scherer, Gro Gausdal, Sabine Leh, Jessica Furriol, Øystein Solberg Eikrem, Salwa Suliman, Tarig Al-Hadi Osman, Lea Landolt, Hans-Peter Marti, Lavina Ahmed, James B. Lorens, Trude Skogstrand, Janka Bábíčková

المساهمون: Institute for Molecular Medicine Finland

المصدر: Physiological Reports
Physiological Reports, Vol 7, Iss 10, Pp n/a-n/a (2019)

مصطلحات موضوعية: CHRONIC KIDNEY-DISEASE, Male, Pathology, Physiology, Bemcentinib (BGB324), TO-MESENCHYMAL TRANSITION, RECEPTOR TYROSINE KINASES, 030204 cardiovascular system & hematology, Kidney, lcsh:Physiology, Signalling Pathways, chemistry.chemical_compound, 0302 clinical medicine, Fibrosis, Myofibroblasts, Original Research, Extracellular Matrix Proteins, UUO, lcsh:QP1-981, renal fibrosis, Renal Conditions, Disorders and Treatments, 3. Good health, Benzocycloheptenes, medicine.anatomical_structure, Immunohistochemistry, Kidney Diseases, Inflammation Mediators, Myofibroblast, Signal Transduction, Ureteral Obstruction, medicine.medical_specialty, Epithelial-Mesenchymal Transition, Immunology, INHIBITION, MECHANISMS, 03 medical and health sciences, INFLAMMATION, Proto-Oncogene Proteins, Physiology (medical), AXL targeting, medicine, Renal fibrosis, Animals, Protein Kinase Inhibitors, Sirius Red, ACCUMULATION, AXL receptor tyrosine kinase, business.industry, Macrophages, Receptor Protein-Tyrosine Kinases, Triazoles, medicine.disease, Axl Receptor Tyrosine Kinase, COLLAGEN, Mice, Inbred C57BL, MICE, Disease Models, Animal, Gene Expression Regulation, chemistry, 3111 Biomedicine, business, 030217 neurology & neurosurgery, Transforming growth factor

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5dcdfc614afb3c4aba1f83364c33ff15
https://doi.org/10.14814/phy2.14091

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مصطلحات الفهرس: Liver Fibrosis, Hepatic Stellate Cells, Bemcentinib (BGB324), GAS6/TAM Signaling, Liver Inflammation, artículo

URL: http://hdl.handle.net/10261/223520
Publisher's version
http://dx.doi.org/10.1016/j.jcmgh.2019.10.010
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