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1
المؤلفون: E. Michael August, Lana Louise Smith Keenan, Jun Li, S. Mariana Margarit, Alexander Heim-Riether, Hans-Dieter Junker, Kathleen Haverty, Neil A. Farrow, Brandon Collins, Bennett T. Farmer, Thomas Neumann, Shuang Liang, John R. Proudfoot, Renate Sekul, Qiang Zhang, Donghong Amy Gao, Steven John Taylor, Zhaoming Xiong, Neil Moss, Melissa Hill-Drzewi
المصدر: Bioorganic & Medicinal Chemistry Letters. 19:5321-5324
مصطلحات موضوعية: Models, Molecular, Matrix metalloproteinase inhibitor, medicine.drug_class, Stereochemistry, Clinical Biochemistry, Pharmaceutical Science, Carboxamide, Matrix Metalloproteinase Inhibitors, Biochemistry, Structure-Activity Relationship, Catalytic Domain, Matrix Metalloproteinase 13, Drug Discovery, medicine, Potency, Structure–activity relationship, Protease Inhibitors, Molecular Biology, Chelating Agents, chemistry.chemical_classification, biology, Organic Chemistry, Active site, Enzyme, chemistry, Enzyme inhibitor, biology.protein, Molecular Medicine, Selectivity, Protein Binding
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2
المؤلفون: Eugene R. Hickey, Anthony S. Prokopowicz, George E. Lee, Carol Ann Homon, Scott Jakes, Wang Mao, Jun Li, Charlene Peng, Bennett T. Farmer, Scott F. Leonard, Mohammed A. Kashem, Kevin Chungeng Qian, Charles L. Cywin, Lian Wang, Ronald Magboo, Morgan Welzel, John P. Wolak, Edward Pack, Tina Morwick
المصدر: Journal of Medicinal Chemistry. 52:1814-1827
مصطلحات موضوعية: Models, Molecular, Binding Sites, Phenylpropionates, Kinase, Chemistry, Stereochemistry, High-throughput screening, Stereoisomerism, Azepines, Hit to lead, Crystallography, X-Ray, Homology (biology), Structure-Activity Relationship, Crystallography, Proto-Oncogene Proteins c-pim-1, hemic and lymphatic diseases, Drug Discovery, Molecular Medicine, Structure–activity relationship, Transferase, Kinase binding, Binding site, Casein Kinase II
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3
المؤلفون: Dianlin Xie, Ning Yan, Matthew D. Healy, Keith L. Constantine, Joseph Yanchunas, Brian A. Dougherty, Li Tao, Jane A. Thanassi, Bennett T. Farmer, Stanley R. Krystek, Michael L. Doyle, Valentina Goldfarb, Nathan O. Siemers
المصدر: Protein Science. 14:1472-1484
مصطلحات موضوعية: biology, Stereochemistry, Chemistry, Molecular Sequence Data, Active site, Sequence alignment, Methyltransferases, computer.file_format, Protein structure prediction, Protein Data Bank, Biochemistry, Article, Protein Structure, Tertiary, Streptococcus pneumoniae, Protein structure, Bacterial Proteins, Structural Homology, Protein, Essential gene, biology.protein, Amino Acid Sequence, Molecular Biology, computer, Peptide sequence, Protein secondary structure
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4
المؤلفون: Venkata Velvadapu, Bennett T. Farmer, Allen B. Reitz
مصطلحات موضوعية: Generation process, Drug discovery, Computer science, Fragment-based lead discovery, Computational biology, New drug application
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::61dccfa48f73ff06c107514dbe2ba2c5
https://doi.org/10.1016/b978-0-12-417205-0.00007-9 -
5
المؤلفون: Anne Badel, Patrick Bazzini, Frans M. Belpaire, Alexandre Borrel, Koen Boussery, Christopher Brice, Anne-Claude Camproux, David Cavalla, Paola Ciapetti, Hongming Chen, Yong Mi Choi-Sledeski, Bernd Clement, Gordon M. Cragg, Patrick M. Dansette, Pierre deMontigny, Ji-Cui Dong, Iain G. Dougall, Ola Engkvist, Bernard Faller, Bennett T. Farmer, Delphine Flatters, Bruno Galli, Colette Geneix, Bruno Giethlen, Serge Grisoni, Gerhard Gross, David Harris, Yuichi Hashimoto, Chris Ho, Andrew L. Hopkins, Hiba Abi Hussein, Peter Imming, Minoru Ishikawa, Tim Jonckers, Sabine Kopp, David G.I. Kingston, Thierry Kogej, Sophie Lasseur, Dominique Lesuisse, Harvey Lieberman, Richard Luthi, Anne-Christine Macherey, André Mann, Raffaella G. Balocco Mattavelli, Christophe Morice, Richard Morphy, David J. Newman, Anne Olivier, Michel Petitjean, Pierre Raboisson, Zoran Rankovic, Leslie Regad, Allen B. Reitz, Bernd U. Riebesehl, Jean-Philippe Rocher, Tiago Rodrigues, A. Romeo, Jean-Michel Rondeau, Laurent Schaeffer, Jean-Michel Scherrmann, Gisbert Schneider, Herman Schreuder, Wolfgang Sippl, Erin M. Skoda, Olivier Taboureau, Bernard Testa, John Unitt, Johan Van de Voorde, Walter M.M. Van den Broeck, N. Murti Vemuri, Venkata Velvadapu, Franz Weiberth, Bruno Villoutreix, Camille G. Wermuth, Peter Wipf, Gerhard Wolber
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::9ac78ac235601f775503cbb8ecc81d18
https://doi.org/10.1016/b978-0-12-417205-0.00044-4 -
6
المؤلفون: William J. Metzler, Keith L. Constantine, Stephen R. Johnson, Patricia A. McDonnell, Thomas J. Caulfield, David R. Magnin, Richard B. Sulsky, Jeffrey A. Robl, Luciano Mueller, Valentina Goldfarb, David S. Taylor, Bennett T. Farmer, Rex A. Parker, Leonard P. Adam
المصدر: Journal of Medicinal Chemistry. 49:5013-5017
مصطلحات موضوعية: Keratinocytes, Models, Molecular, Binding Sites, Magnetic Resonance Spectroscopy, Molecular Structure, Protein family, Molecular model, Chemistry, Stereochemistry, Binding protein, Fatty Acid-Binding Proteins, Ligands, Mandelic acid, Small molecule, Fatty acid-binding protein, chemistry.chemical_compound, Drug Discovery, Benzyl group, Humans, Molecular Medicine, Moiety, Computer Simulation
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7
المؤلفون: and Luciano Mueller, Rex A. Parker, Michael Wittekind, Mark S. Friedrichs, Ching-Hsuen Chu, Keith L. Constantine, Ii‡ Bennett T. Farmer, Valentina Goldfarb, Jamil Haris
المصدر: Biochemistry. 37:7965-7980
مصطلحات موضوعية: Intracellular Fluid, Models, Molecular, Protein Conformation, Stereochemistry, Nerve Tissue Proteins, Fatty Acid-Binding Proteins, Myelin P2 Protein, Biochemistry, Fatty acid-binding protein, Mice, chemistry.chemical_compound, Adipocyte, Adipocytes, Side chain, Animals, Humans, Molecule, Computer Simulation, Muscle, Skeletal, Nuclear Magnetic Resonance, Biomolecular, Nitrogen Isotopes, Chemistry, Tumor Suppressor Proteins, Dynamics (mechanics), Relaxation (NMR), Metabolism, Neoplasm Proteins, Cytosol, Thermodynamics, lipids (amino acids, peptides, and proteins), Carrier Proteins, Fatty Acid-Binding Protein 7, Hydrogen, Protein Binding
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8
المصدر: Journal of the American Chemical Society. 118:3253-3261
مصطلحات موضوعية: Dipole, Colloid and Surface Chemistry, Nuclear magnetic resonance, Field (physics), Chemical physics, Chemistry, Intermolecular force, Resonance, General Chemistry, Biochemistry, Two-dimensional nuclear magnetic resonance spectroscopy, Catalysis, Characterization (materials science)
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9
المؤلفون: Chih Chin Huang, Carol A. Fierke, Ronald A. Venters, Leonard D. Spicer, Ronald Trolard, Bennett T. Farmer
المصدر: Journal of Biomolecular NMR. 5:339-344
مصطلحات موضوعية: Deuterium NMR, Carbon Isotopes, Magnetic Resonance Spectroscopy, Molecular Structure, Nitrogen Isotopes, Chemistry, Stereochemistry, Carbonic anhydrase II, Proteins, Pulse sequence, Deuterium, Biochemistry, Mass Spectrometry, chemistry.chemical_compound, Nuclear magnetic resonance, Isotopic shift, Escherichia coli, Humans, Molecule, Ammonium chloride, Sodium acetate, Spectroscopy, Carbonic Anhydrases
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10
المصدر: Journal of Magnetic Resonance, Series B. 107:197-200
مصطلحات موضوعية: Chemistry, Computational chemistry, Simple (abstract algebra), Hydrogen-1, Carbon-13, General Engineering, Analytical chemistry, Identification (biology), Pulse sequence, Nuclear Overhauser effect