المؤلفون: van Rheenen, Wouter, van der Spek, Rick AA, Bakker, Mark K, van Vugt, Joke JFA, Hop, Paul J, Zwamborn, Ramona AJ, de Klein, Niek, Westra, Harm-Jan, Bakker, Olivier B, Deelen, Patrick, Shireby, Gemma, Hannon, Eilis, Moisse, Matthieu, Baird, Denis, Restuadi, Restuadi, Dolzhenko, Egor, Dekker, Annelot M, Gawor, Klara, Westeneng, Henk-Jan, Tazelaar, Gijs HP, van Eijk, Kristel R, Kooyman, Maarten, Byrne, Ross P, Doherty, Mark, Heverin, Mark, Al Khleifat, Ahmad, Iacoangeli, Alfredo, Shatunov, Aleksey, Ticozzi, Nicola, Cooper-Knock, Johnathan, Smith, Bradley N, Gromicho, Marta, Chandran, Siddharthan, Pal, Suvankar, Morrison, Karen E, Shaw, Pamela J, Hardy, John, Orrell, Richard W, Sendtner, Michael, Meyer, Thomas, Başak, Nazli, van der Kooi, Anneke J, Ratti, Antonia, Fogh, Isabella, Gellera, Cinzia, Lauria, Giuseppe, Corti, Stefania, Cereda, Cristina, Sproviero, Daisy, D’Alfonso, Sandra, Sorarù, Gianni, Siciliano, Gabriele, Filosto, Massimiliano, Padovani, Alessandro, Chiò, Adriano, Calvo, Andrea, Moglia, Cristina, Brunetti, Maura, Canosa, Antonio, Grassano, Maurizio, Beghi, Ettore, Pupillo, Elisabetta, Logroscino, Giancarlo, Nefussy, Beatrice, Osmanovic, Alma, Nordin, Angelica, Lerner, Yossef, Zabari, Michal, Gotkine, Marc, Baloh, Robert H, Bell, Shaughn, Vourc’h, Patrick, Corcia, Philippe, Couratier, Philippe, Millecamps, Stéphanie, Meininger, Vincent, Salachas, François, Mora Pardina, Jesus S, Assialioui, Abdelilah, Rojas-García, Ricardo, Dion, Patrick A, Ross, Jay P, Ludolph, Albert C, Weishaupt, Jochen H, Brenner, David, Freischmidt, Axel, Bensimon, Gilbert, Brice, Alexis, Durr, Alexandra, Payan, Christine AM, Saker-Delye, Safa, Wood, Nicholas W, Topp, Simon, Rademakers, Rosa, Tittmann, Lukas, Lieb, Wolfgang, Franke, Andre, Ripke, Stephan, Braun, Alice, Kraft, Julia

المصدر: Nature Genetics. 53(12)

مصطلحات موضوعية: Human Genome, Neurodegenerative, Clinical Research, Rare Diseases, Prevention, ALS, Neurosciences, Genetics, Brain Disorders, Aetiology, 2.1 Biological and endogenous factors, Neurological, Amyotrophic Lateral Sclerosis, Brain, Cholesterol, Disease Progression, Female, Genome-Wide Association Study, Glutamine, Humans, Male, Mendelian Randomization Analysis, Microsatellite Repeats, Mutation, Neurodegenerative Diseases, Neurons, Quantitative Trait Loci, RNA-Seq, Risk Factors, SLALOM Consortium, PARALS Consortium, SLAGEN Consortium, SLAP Consortium, Biological Sciences, Medical and Health Sciences, Developmental Biology

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المؤلفون: Lim, Tiong Y., Perpiñán, Elena, Londoño, Maria-Carlota, Miquel, Rosa, Ruiz, Paula, Kurt, Ada S., Kodela, Elisavet, Cross, Amy R., Berlin, Claudia, Hester, Joanna, Issa, Fadi, Douiri, Abdel, Volmer, Felix H., Taubert, Richard, Williams, Evangelia, Demetris, Anthony J., Lesniak, Andrew, Bensimon, Gilbert, Lozano, Juan José, Martinez-Llordella, Marc, Tree, Tim, Sánchez-Fueyo, Alberto

المصدر: In Journal of Hepatology January 2023 78(1):153-164

المؤلفون: Chen, Zhongbo, Chen, Jason A, Shatunov, Aleksey, Jones, Ashley R, Kravitz, Stephanie N, Huang, Alden Y, Lawrence, Lauren, Lowe, Jennifer K, Lewis, Cathryn M, Payan, Christine AM, Lieb, Wolfgang, Franke, Andre, Deloukas, Panagiotis, Amouyel, Philippe, Tzourio, Christophe, Dartigues, Jean‐François, Groups, NNIPPS and BBBIPPS Study, Ludolph, Albert, Bensimon, Gilbert, Leigh, P Nigel, Bronstein, Jeff M, Coppola, Giovanni, Geschwind, Daniel H, Al‐Chalabi, Ammar

المصدر: Movement Disorders. 34(7)

مصطلحات موضوعية: Biomedical and Clinical Sciences, Neurosciences, Clinical Sciences, Prevention, Clinical Research, Neurodegenerative, Genetics, Brain Disorders, Rare Diseases, Genetic Testing, Human Genome, Aetiology, 2.1 Biological and endogenous factors, Neurological, Adult, Age of Onset, Aged, Aged, 80 and over, DNA Copy Number Variations, Female, Genome-Wide Association Study, Genotype, Humans, Male, Middle Aged, Polymorphism, Single Nucleotide, Supranuclear Palsy, Progressive, tau Proteins, copy number variation, genome-wide association study, progressive supranuclear palsy, NNIPPS and BBBIPPS Study Groups, Human Movement and Sports Sciences, Neurology & Neurosurgery, Clinical sciences

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URL الوصول: https://escholarship.org/uc/item/1fg3g3t6

المؤلفون: Chen, Jason A, Chen, Zhongbo, Won, Hyejung, Huang, Alden Y, Lowe, Jennifer K, Wojta, Kevin, Yokoyama, Jennifer S, Bensimon, Gilbert, Leigh, P Nigel, Payan, Christine, Shatunov, Aleksey, Jones, Ashley R, Lewis, Cathryn M, Deloukas, Panagiotis, Amouyel, Philippe, Tzourio, Christophe, Dartigues, Jean-Francois, Ludolph, Albert, Boxer, Adam L, Bronstein, Jeff M, Al-Chalabi, Ammar, Geschwind, Daniel H, Coppola, Giovanni

المصدر: Molecular neurodegeneration. 13(1)

مصطلحات موضوعية: Humans, Supranuclear Palsy, Progressive, Neurodegenerative Diseases, Genetic Predisposition to Disease, Genotype, Polymorphism, Single Nucleotide, Female, Male, Genome-Wide Association Study, Genome-wide association study, Neurodegeneration, Progressive supranuclear palsy, Supranuclear Palsy, Progressive, Polymorphism, Single Nucleotide, Prevention, Clinical Trials and Supportive Activities, Neurodegenerative, Rare Diseases, Genetics, Human Genome, Clinical Research, 2.1 Biological and endogenous factors, Neurological, Clinical Sciences, Neurosciences, Neurology & Neurosurgery

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المؤلفون: van Rheenen, Wouter, Shatunov, Aleksey, Dekker, Annelot M, McLaughlin, Russell L, Diekstra, Frank P, Pulit, Sara L, van der Spek, Rick AA, Võsa, Urmo, de Jong, Simone, Robinson, Matthew R, Yang, Jian, Fogh, Isabella, van Doormaal, Perry Tc, Tazelaar, Gijs HP, Koppers, Max, Blokhuis, Anna M, Sproviero, William, Jones, Ashley R, Kenna, Kevin P, van Eijk, Kristel R, Harschnitz, Oliver, Schellevis, Raymond D, Brands, William J, Medic, Jelena, Menelaou, Androniki, Vajda, Alice, Ticozzi, Nicola, Lin, Kuang, Rogelj, Boris, Vrabec, Katarina, Ravnik-Glavač, Metka, Koritnik, Blaž, Zidar, Janez, Leonardis, Lea, Grošelj, Leja Dolenc, Millecamps, Stéphanie, Salachas, François, Meininger, Vincent, de Carvalho, Mamede, Pinto, Susana, Mora, Jesus S, Rojas-García, Ricardo, Polak, Meraida, Chandran, Siddharthan, Colville, Shuna, Swingler, Robert, Morrison, Karen E, Shaw, Pamela J, Hardy, John, Orrell, Richard W, Pittman, Alan, Sidle, Katie, Fratta, Pietro, Malaspina, Andrea, Topp, Simon, Petri, Susanne, Abdulla, Susanne, Drepper, Carsten, Sendtner, Michael, Meyer, Thomas, Ophoff, Roel A, Staats, Kim A, Wiedau-Pazos, Martina, Lomen-Hoerth, Catherine, Van Deerlin, Vivianna M, Trojanowski, John Q, Elman, Lauren, McCluskey, Leo, Basak, A Nazli, Tunca, Ceren, Hamzeiy, Hamid, Parman, Yesim, Meitinger, Thomas, Lichtner, Peter, Radivojkov-Blagojevic, Milena, Andres, Christian R, Maurel, Cindy, Bensimon, Gilbert, Landwehrmeyer, Bernhard, Brice, Alexis, Payan, Christine AM, Saker-Delye, Safaa, Dürr, Alexandra, Wood, Nicholas W, Tittmann, Lukas, Lieb, Wolfgang, Franke, Andre, Rietschel, Marcella, Cichon, Sven, Nöthen, Markus M, Amouyel, Philippe, Tzourio, Christophe, Dartigues, Jean-François, Uitterlinden, Andre G, Rivadeneira, Fernando, Estrada, Karol, Hofman, Albert, Curtis, Charles, Blauw, Hylke M

المصدر: Nature genetics. 48(9)

مصطلحات موضوعية: PARALS Registry, SLALOM Group, SLAP Registry, FALS Sequencing Consortium, SLAGEN Consortium, NNIPPS Study Group, Humans, Amyotrophic Lateral Sclerosis, Genetic Predisposition to Disease, Proteins, Cytoskeletal Proteins, Myelin Proteins, Case-Control Studies, Cohort Studies, Mutation, Netherlands, Munc18 Proteins, Genome-Wide Association Study, Neurosciences, Rare Diseases, Brain Disorders, Biotechnology, Prevention, Human Genome, Neurodegenerative, Genetics, ALS, Aetiology, 2.1 Biological and endogenous factors, Biological Sciences, Medical and Health Sciences, Developmental Biology

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URL الوصول: https://escholarship.org/uc/item/22r175sv

المؤلفون: van Rheenen, Wouter^{Aff1, IDs41588022010203_cor1}, van der Spek, Rick A. A., Bakker, Mark K., van Vugt, Joke J. F. A., Hop, Paul J., Zwamborn, Ramona A. J., de Klein, Niek, Westra, Harm-Jan, Bakker, Olivier B., Deelen, Patrick^{Aff2, Aff3}, Shireby, Gemma, Hannon, Eilis, Moisse, Matthieu^{Aff5, Aff6, Aff7}, Baird, Denis^{Aff8, Aff9}, Restuadi, Restuadi, Dolzhenko, Egor, Dekker, Annelot M., Gawor, Klara, Westeneng, Henk-Jan, Tazelaar, Gijs H. P., van Eijk, Kristel R., Kooyman, Maarten, Byrne, Ross P., Doherty, Mark, Heverin, Mark, Al Khleifat, Ahmad, Iacoangeli, Alfredo^{Aff14, Aff15, Aff16}, Shatunov, Aleksey, Ticozzi, Nicola^{Aff17, Aff18}, Cooper-Knock, Johnathan, Smith, Bradley N., Gromicho, Marta, Chandran, Siddharthan^{Aff21, Aff22}, Pal, Suvankar^{Aff21, Aff22}, Morrison, Karen E., Shaw, Pamela J., Hardy, John, Orrell, Richard W., Sendtner, Michael, Meyer, Thomas, Başak, Nazli, van der Kooi, Anneke J., Ratti, Antonia^{Aff17, Aff30}, Fogh, Isabella, Gellera, Cinzia, Lauria, Giuseppe^{Aff32, Aff33}, Corti, Stefania^{Aff18, Aff34}, Cereda, Cristina, Sproviero, Daisy, D’Alfonso, Sandra, Sorarù, Gianni, Siciliano, Gabriele, Filosto, Massimiliano, Padovani, Alessandro, Chiò, Adriano^{Aff40, Aff41}, Calvo, Andrea^{Aff40, Aff41}, Moglia, Cristina^{Aff40, Aff41}, Brunetti, Maura, Canosa, Antonio^{Aff40, Aff41}, Grassano, Maurizio, Beghi, Ettore, Pupillo, Elisabetta, Logroscino, Giancarlo, Nefussy, Beatrice, Osmanovic, Alma^{Aff45, Aff46}, Nordin, Angelica, Lerner, Yossef^{Aff48, Aff49}, Zabari, Michal^{Aff48, Aff49}, Gotkine, Marc^{Aff48, Aff49}, Baloh, Robert H.^{Aff50, Aff51}, Bell, Shaughn^{Aff50, Aff51}, Vourc’h, Patrick^{Aff52, Aff53}, Corcia, Philippe^{Aff53, Aff54}, Couratier, Philippe^{Aff55, Aff56}, Millecamps, Stéphanie, Meininger, Vincent, Salachas, François^{Aff57, Aff59}, Mora Pardina, Jesus S., Assialioui, Abdelilah, Rojas-García, Ricardo, Dion, Patrick A.^{Aff63, Aff64}, Ross, Jay P.^{Aff63, Aff65}, Ludolph, Albert C., Weishaupt, Jochen H., Brenner, David, Freischmidt, Axel^{Aff66, Aff68}, Bensimon, Gilbert^{Aff69, Aff70, Aff71, Aff72}, Brice, Alexis, Durr, Alexandra, Payan, Christine A. M., Saker-Delye, Safa, Wood, Nicholas W., Topp, Simon, Rademakers, Rosa, Tittmann, Lukas, Lieb, Wolfgang, Franke, Andre, Ripke, Stephan^{Aff79, Aff80, Aff81}, Braun, Alice, Kraft, Julia, Whiteman, David C., Olsen, Catherine M., Uitterlinden, Andre G.^{Aff83, Aff84}, Hofman, Albert, Rietschel, Marcella^{Aff85, Aff86}, Cichon, Sven^{Aff87, Aff88, Aff89, Aff90}, Nöthen, Markus M.^{Aff87, Aff88}, Amouyel, Philippe, Traynor, Bryan J.^{Aff92, Aff93}, Singleton, Andrew B., Mitne Neto, Miguel, Cauchi, Ruben J., Ophoff, Roel A.^{Aff97, Aff98, Aff99}, Wiedau-Pazos, Martina, Lomen-Hoerth, Catherine, van Deerlin, Vivianna M., Grosskreutz, Julian^{Aff103, Aff104}, Roediger, Annekathrin, Gaur, Nayana, Jörk, Alexander, Barthel, Tabea, Theele, Erik, Ilse, Benjamin, Stubendorff, Beatrice, Witte, Otto W., Steinbach, Robert, Hübner, Christian A., Graff, Caroline, Brylev, Lev^{Aff107, Aff108, Aff109}, Fominykh, Vera^{Aff107, Aff109}, Demeshonok, Vera, Ataulina, Anastasia, Rogelj, Boris^{Aff111, Aff112, Aff113}, Koritnik, Blaž, Zidar, Janez, Ravnik-Glavač, Metka, Glavač, Damjan, Stević, Zorica, Drory, Vivian^{Aff44, Aff118}, Povedano, Monica, Blair, Ian P., Kiernan, Matthew C., Benyamin, Beben^{Aff10, Aff121}, Henderson, Robert D.^{Aff122, Aff123}, Furlong, Sarah, Mathers, Susan, McCombe, Pamela A.^{Aff123, Aff125}, Needham, Merrilee^{Aff126, Aff127, Aff128}, Ngo, Shyuan T.^{Aff122, Aff123, Aff125}, Nicholson, Garth A.^{Aff119, Aff129, Aff130}, Pamphlett, Roger, Rowe, Dominic B., Steyn, Frederik J.^{Aff123, Aff132}, Williams, Kelly L., Mather, Karen A.^{Aff133, Aff134}, Sachdev, Perminder S.^{Aff133, Aff135}, Henders, Anjali K., Wallace, Leanne, de Carvalho, Mamede, Pinto, Susana, Petri, Susanne, Weber, Markus, Rouleau, Guy A.^{Aff63, Aff64, Aff65}, Silani, Vincenzo^{Aff17, Aff18}, Curtis, Charles J.^{Aff137, Aff138}, Breen, Gerome^{Aff137, Aff138}, Glass, Jonathan D., Brown, Jr., Robert H., Landers, John E., Shaw, Christopher E., Andersen, Peter M., Groen, Ewout J. N., van Es, Michael A., Pasterkamp, R. Jeroen, Fan, Dongsheng, Garton, Fleur C., McRae, Allan F., Davey Smith, George^{Aff9, Aff143}, Gaunt, Tom R.^{Aff9, Aff143}, Eberle, Michael A., Mill, Jonathan, McLaughlin, Russell L., Hardiman, Orla, Kenna, Kevin P.^{Aff1, Aff141}, Wray, Naomi R.^{Aff10, Aff125}, Tsai, Ellen, Runz, Heiko, Franke, Lude, Al-Chalabi, Ammar^{Aff14, Aff144}, Van Damme, Philip^{Aff5, Aff6, Aff7}, van den Berg, Leonard H., Veldink, Jan H.^{Aff1, IDs41588022010203_cor196}

المصدر: Nature Genetics. 54(3):361-361

المؤلفون: Fang, Ton, Al Khleifat, Ahmad, Meurgey, Jacques-Henri, Jones, Ashley, Leigh, P Nigel, Bensimon, Gilbert, Al-Chalabi, Ammar

المصدر: In The Lancet Neurology May 2018 17(5):416-422

المؤلفون: Hartemann, Agnès, Bensimon, Gilbert, Payan, Christine A, Jacqueminet, Sophie, Bourron, Olivier, Nicolas, Nathalie, Fonfrede, Michèle, Rosenzwajg, Michelle, Bernard, Claude, Klatzmann, David

المصدر: In The Lancet Diabetes & Endocrinology December 2013 1(4):295-305

المؤلفون: Hop, Paul J., Zwamborn, Ramona A. J., Hannon, Eilis, Shireby, Gemma L., Nabais, Marta F., Walker, Emma M., van Rheenen, Wouter, van Vugt, Joke J. F. A., Dekker, Annelot M., Westeneng, Henk-Jan, Tazelaar, Gijs H. P., Slagboom, P. Eline, Beekman, Marian, Deelen, Joris, van Heemst, Diana, Veldink, Jan H., van den Berg, Leonard H., van Duijn, Cornelia M., Hofman, Bert A., Isaacs, Aaron, Uitterlinden, Andre G., van Eijk, Kristel R., van Meurs, Joyce, Jhamai, P. Mila, Verbiest, Michael, Suchiman, H. Eka D., Verkerk, Marijn, van der Breggen, Ruud, van Rooij, Jeroen, Lakenberg, Nico, Mei, Hailiang, van Iterson, Maarten, Moisse, Matthieu, van Galen, Michiel, Bot, Jan, Zhernakova, Dasha V., Jansen, Rick, van ‘t Hof, Peter, Deelen, Patrick, Nooren, Irene, t Hoen, Peter A. C., Heijmans, Bastiaan T., Moed, Matthijs, Baird, Denis, Franke, Lude, Vermaat, Martijn, Luijk, Rene, Jan Bonder, Marc, van Dijk, Freerk, Arindrarto, Wibowo, Al Khleifat, Ahmad, Kielbasa, Szymon M., Swertz, Morris A., van Zwet, Erik W., Al-Chalabi, Ammar, Wray, Naomi R., Bensimon, Gilbert, Hardiman, Orla, Iacoangeli, Alfredo, Chio, Adriano, Smith, George Davey, Mill, Jonathan, Ticozzi, Nicola, Ratti, Antonia, Cooper-Knock, Jonathan, Morrison, Karen E., Shaw, Pamela J., Basak, A. Nazli, Chiò, Adriano, Calvo, Andrea, Moglia, Cristina, Canosa, Antonio, Brunetti, Maura, Grassano, Maurizio, Gotkine, Marc, Lerner, Yossef, Zabari, Michal, Vourc’h, Patrick, Corcia, Philippe, Couratier, Philippe, Mora Pardina, Jesus S., Salas, Teresa, Dion, Patrick, Ross, Jay P., Henderson, Robert D., Mathers, Susan, McCombe, Pamela A., Needham, Merrilee, Nicholson, Garth, Rowe, Dominic B., Pamphlett, Roger, Mather, Karen A., Sachdev, Perminder S., Furlong, Sarah, Garton, Fleur C., Henders, Anjali K., Lin, Tian, Ngo, Shyuan T., Steyn, Frederik J., Wallace, Leanne, Williams, Kelly L., Neto, Miguel Mitne, Cauchi, Ruben J., Blair, Ian P., Kiernan, Matthew C., Drory, Vivian, Povedano, Monica, Carvalho, Mamede, Pinto, Susana, Weber, Markus, Rouleau, Guy A., Silani, Vincenzo, Landers, John E., Shaw, Christopher E., Andersen, Peter M., McRae, Allan F., van Es, Michael A., Pasterkamp, R. Jeroen, McLaughlin, Russell L., Kenna, Kevin P., Tsai, Ellen, Runz, Heiko, Van Damme, Philip, Boomsma, Dorret I., Pool, Rene, van Dongen, Jenny, Hottenga, Joukje J., van Greevenbroek, Marleen M. J., Stehouwer, Coen D.A., van der Kallen, Carla J.H., Schalkwijk, Casper G., Wijmenga, Cisca, Zhernakova, Sasha, Tigchelaar, Ettje F.

المساهمون: Stem Cell Aging Leukemia and Lymphoma (SALL), Groningen Institute for Gastro Intestinal Genetics and Immunology (3GI), Translational Immunology Groningen (TRIGR), Psychiatry, Amsterdam Neuroscience - Complex Trait Genetics, Laboratory Medicine, APH - Mental Health, Internal Medicine, Epidemiology, Repositório da Universidade de Lisboa

المصدر: Science Translational Medicine, 14(633):eabj0264. AMER ASSOC ADVANCEMENT SCIENCE
Science Translational Medicine, 14(633):eabj0264. American Association for the Advancement of Science
Hop, P J, Zwamborn, R A J, Hannon, E, Shireby, G L, Nabais, M F, Walker, E M, van Rheenen, W, van Vugt, J J F A, Dekker, A M, Westeneng, H J, Tazelaar, G H P, van Eijk, K R, Moisse, M, Baird, D, Al Khleifat, A, Iacoangeli, A, Ticozzi, N, Ratti, A, Cooper-Knock, J, Morrison, K E, Shaw, P J, Basak, A N, Chiò, A, Calvo, A, Moglia, C, Canosa, A, Brunetti, M, Grassano, M, Gotkine, M, Lerner, Y, Zabari, M, Vourc'H, P, Corcia, P, Couratier, P, Mora Pardina, J S, Salas, T, Dion, P, Ross, J P, Henderson, R D, Mathers, S, McCombe, P A, Needham, M, Nicholson, G, Rowe, D B, Pamphlett, R, Mather, K A, Sachdev, P S & Furlong, S & Shaw, C E & Al-Chalabi, A 2022, ' Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS ', Science Translational Medicine, vol. 14, no. 633, eabj0264 . https://doi.org/10.1126/scitranslmed.abj0264
Science Translational Medicine, 14633
BIOS Consortium 2022, ' Genome-wide study of DNA methylation shows alterations in metabolic, inflammatory, and cholesterol pathways in ALS ', Science Translational Medicine, vol. 14, no. 633, eabj0264, pp. eabj0264 . https://doi.org/10.1126/scitranslmed.abj0264
Sci Transl Med

مصطلحات موضوعية: Cholesterol, Amyotrophic Lateral Sclerosis, Humans, Neurodegenerative Diseases, General Medicine, DNA Methylation, Nanomedicine Radboud Institute for Molecular Life Sciences [Radboudumc 19], Article, Epigenesis, Genetic, Genome-Wide Association Study

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URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::04495e1fac05acb2703581971447b8c1
https://hdl.handle.net/11370/70304f9f-5b0d-47ff-a7fa-be1edbd253ff