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1دورية أكاديمية
المؤلفون: Heather N. Tinsley, Bini Mathew, Xi Chen, Yulia Y. Maxuitenko, Nan Li, Whitney M. Lowe, Jason D. Whitt, Wei Zhang, Bernard D. Gary, Adam B. Keeton, William E. Grizzle, Clinton J. Grubbs, Robert C. Reynolds, Gary A. Piazza
المصدر: Cancers, Vol 15, Iss 3, p 646 (2023)
مصطلحات موضوعية: nonsteroidal anti-inflammatory drug (NSAID), cyclooxygenase (COX), cyclic guanosine monophosphate (cGMP), phosphodiesterase (PDE), breast cancer, sulindac, Neoplasms. Tumors. Oncology. Including cancer and carcinogens, RC254-282
وصف الملف: electronic resource
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2دورية أكاديمية
المؤلفون: Gary A. Piazza, Adam B. Keeton, Heather N. Tinsley, Jason D. Whitt, Bernard D. Gary, Bini Mathew, Raj Singh, William E. Grizzle, Robert C. Reynolds
المصدر: Pharmaceuticals, Vol 3, Iss 5, Pp 1652-1667 (2010)
مصطلحات موضوعية: NSAIDs, sulindac, cancer, colon, chemoprevention, Medicine, Pharmacy and materia medica, RS1-441
وصف الملف: electronic resource
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3دورية أكاديمية
المؤلفون: Ritu Arora, Clayton Yates, Bernard D Gary, Steven McClellan, Ming Tan, Yaguang Xi, Eddie Reed, Gary A Piazza, Laurie B Owen, Windy Dean-Colomb
المصدر: PLoS ONE, Vol 9, Iss 6, p e98370 (2014)
وصف الملف: electronic resource
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4
المؤلفون: Ashley S. Lindsey, Joel Andrews, Gary A. Piazza, Nan Li, Adam B. Keeton, Bernard D. Gary, Kevin Lee
المصدر: Oncotarget
مصطلحات موضوعية: 0301 basic medicine, Phosphodiesterase Inhibitors, Apoptosis, medicine.disease_cause, 03 medical and health sciences, 0302 clinical medicine, Cell Line, Tumor, Survivin, medicine, Humans, Gene silencing, PKA, beta Catenin, Cell Proliferation, PDE10A, Oncogene, business.industry, PKG, Phosphodiesterase, β-catenin, 3. Good health, 030104 developmental biology, colon cancer, Oncology, 030220 oncology & carcinogenesis, Immunology, Cancer cell, Cancer research, Colorectal Neoplasms, Carcinogenesis, business, Research Paper, Signal Transduction
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e045d4fa02b05bf603bf81dd83b1a64
https://doi.org/10.18632/oncotarget.6705 -
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المؤلفون: Gary A. Piazza, Mohamed Abdel-Aziz, Hamdy M. Abdel-Rahman, Joshua C. Canzoneri, Bernard D. Gary
المصدر: Archiv der Pharmazie. 347:650-657
مصطلحات موضوعية: Schiff base, biology, Stereochemistry, Chemistry, Pharmaceutical Science, Active site, Combinatorial chemistry, In vitro, chemistry.chemical_compound, PDE4B, Docking (molecular), Cell culture, Drug Discovery, medicine, biology.protein, IC50, Rolipram, medicine.drug
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6
المؤلفون: Kevin Lee, Alexandra M. Fajardo, Bernard D. Gary, Suzanne Russo, Evrim Gurpinar, Mary Pat Moyer, Veronica Ramirez-Alcantara, John T. Piazza, Xi Chen, Sara Sigler, Adam B. Keeton, Danuel J. Laan, Wenyan Lu, Meagan Thomas, Yonghe Li, Yaguang Xi, Joshua C. Canzoneri, Joel Andrews, Larry Yet, Gary A. Piazza, Nan Li, William E. Grizzle, Brian T. Eberhardt, Bing Zhu
المصدر: Oncogene
مصطلحات موضوعية: Cancer Research, Small interfering RNA, Transcription, Genetic, Phosphodiesterase Inhibitors, colorectal cancer, Biology, medicine.disease_cause, Article, Small hairpin RNA, Growth factor receptor, Intestinal mucosa, Cell Line, Tumor, Genetics, medicine, Humans, RNA, Small Interfering, Molecular Biology, beta Catenin, Cell Proliferation, Gene knockdown, Phosphoric Diester Hydrolases, PKG, Phosphodiesterase, β-catenin, Cell cycle, HCT116 Cells, Molecular biology, 3. Good health, Gene Expression Regulation, Neoplastic, cGMP, HEK293 Cells, phosphodiesterase 10, Gene Knockdown Techniques, Colonic Neoplasms, TCF Transcription Factors, Carcinogenesis, HT29 Cells, Signal Transduction
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7
المؤلفون: Gary A. Piazza, Marwa Saeed Hany, Bernard D. Gary, Heather N. Tinsley, Ashraf H. Abadi, Amal Abdel Haleem Eissa, Shimaa Awadain Elsharif
المصدر: Chemical and Pharmaceutical Bulletin. 61:405-410
مصطلحات موضوعية: Formamide, Pyrimidine, Pyridines, Stereochemistry, Phosphodiesterase 3, Phosphodiesterase 3 Inhibitors, Article, Substrate Specificity, Structure-Activity Relationship, chemistry.chemical_compound, Hydrolysis, Catalytic Domain, Drug Discovery, Pyridine, Humans, Cyclic GMP, Cyclic guanosine monophosphate, Cell Proliferation, Binding Sites, Chemistry, General Chemistry, General Medicine, Cyclic Nucleotide Phosphodiesterases, Type 3, Molecular Docking Simulation, Pyrimidines, Cyclization, Amine gas treating, Selectivity, HT29 Cells, Protein Binding
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d761a74f78bc8079ee427337d79614b8
https://doi.org/10.1248/cpb.c12-00993 -
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المؤلفون: Bernard D. Gary, Ashraf H. Abadi, Alexandra M. Fajardo, Amal H. Ali, Gary A. Piazza, Shreen M. El-Nashar, Nermin S. Ahmed, Matthias Negri, Heather N. Tinsley
المصدر: European Journal of Medicinal Chemistry. 57:329-343
مصطلحات موضوعية: Stereochemistry, Substituent, Hydantoin, Diketopiperazines, Molecular Docking Simulation, Article, Protein Structure, Secondary, Tadalafil, Inhibitory Concentration 50, Structure-Activity Relationship, chemistry.chemical_compound, 3',5'-Cyclic-GMP Phosphodiesterases, Drug Discovery, Humans, Structure–activity relationship, Conformational isomerism, Cell Proliferation, Enzyme Assays, Cyclic Nucleotide Phosphodiesterases, Type 5, Pharmacology, Phosphoric Diester Hydrolases, Hydantoins, Organic Chemistry, Hydrogen Bonding, General Medicine, Phosphodiesterase 5 Inhibitors, Piperazinedione, Recombinant Proteins, Kinetics, chemistry, Searching the conformational space for docking, Docking (molecular), Drug Design, Thermodynamics, Carbolines
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المؤلفون: Windy Dean-Colomb, William R. Taylor, Yaguang Xi, Bernard D. Gary, Lalita A. Shevde, Rajeev S. Samant, Donna Lynn Dyess, Xiaobo Li, Gary A. Piazza, Q Cui, Lin Gao
المصدر: Oncogene
مصطلحات موضوعية: Cancer Research, Transcription, Genetic, Biology, Article, NF-κB, 03 medical and health sciences, chemistry.chemical_compound, Sulindac, 0302 clinical medicine, Growth factor receptor, Cell Line, Tumor, Neoplasms, microRNA, Genetics, medicine, Humans, Neoplasm Invasiveness, Molecular Biology, 030304 developmental biology, 0303 health sciences, Anti-Inflammatory Agents, Non-Steroidal, NF-kappa B, Promoter, Cell cycle, invasion, Molecular biology, 3. Good health, MicroRNAs, chemistry, Apoptosis, 030220 oncology & carcinogenesis, Cancer research, Chromatin immunoprecipitation, medicine.drug
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المؤلفون: Hamdy M, Abdel-Rahman, Mohamed, Abdel-Aziz, Heather N, Tinsley, Bernard D, Gary, Joshua C, Canzoneri, Gary A, Piazza
المصدر: Archiv der Pharmazie. 349(2)
مصطلحات موضوعية: Molecular Docking Simulation, Pyridazines, Structure-Activity Relationship, Hydrazones, Humans, Phosphodiesterase 4 Inhibitors, Cyclic Nucleotide Phosphodiesterases, Type 4