المؤلفون: Tran F; Institute of Clinical Molecular Biology, University Medical Center Schleswig-Holstein, Christian Albrecht University Kiel, Campus Kiel, Rosalind-Franklin-Strasse 12, 24105, Kiel, Germany. f.tran@ikmb.uni-kiel.de.; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, 24105, Kiel, Germany. f.tran@ikmb.uni-kiel.de., Scharmacher A; Institute of Clinical Molecular Biology, University Medical Center Schleswig-Holstein, Christian Albrecht University Kiel, Campus Kiel, Rosalind-Franklin-Strasse 12, 24105, Kiel, Germany., Baran N; Institute of Clinical Molecular Biology, University Medical Center Schleswig-Holstein, Christian Albrecht University Kiel, Campus Kiel, Rosalind-Franklin-Strasse 12, 24105, Kiel, Germany., Mishra N; Institute of Clinical Molecular Biology, University Medical Center Schleswig-Holstein, Christian Albrecht University Kiel, Campus Kiel, Rosalind-Franklin-Strasse 12, 24105, Kiel, Germany., Wozny M; Department of Biomedical Sciences, Humanitas University, 20072, Pieve Emanuele, Italy., Chavez SP; Department of Biomedical Sciences, Humanitas University, 20072, Pieve Emanuele, Italy., Bhardwaj A; Institute of Clinical Molecular Biology, University Medical Center Schleswig-Holstein, Christian Albrecht University Kiel, Campus Kiel, Rosalind-Franklin-Strasse 12, 24105, Kiel, Germany., Hinz S; Institute of Clinical Molecular Biology, University Medical Center Schleswig-Holstein, Christian Albrecht University Kiel, Campus Kiel, Rosalind-Franklin-Strasse 12, 24105, Kiel, Germany.; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, 24105, Kiel, Germany., Juzenas S; Institute of Clinical Molecular Biology, University Medical Center Schleswig-Holstein, Christian Albrecht University Kiel, Campus Kiel, Rosalind-Franklin-Strasse 12, 24105, Kiel, Germany.; Institute of Biotechnology, Life Science Centre, Vilnius University, Vilnius, Lithuania., Bernardes JP; Institute of Clinical Molecular Biology, University Medical Center Schleswig-Holstein, Christian Albrecht University Kiel, Campus Kiel, Rosalind-Franklin-Strasse 12, 24105, Kiel, Germany., Sievers LK; Institute of Clinical Molecular Biology, University Medical Center Schleswig-Holstein, Christian Albrecht University Kiel, Campus Kiel, Rosalind-Franklin-Strasse 12, 24105, Kiel, Germany.; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, 24105, Kiel, Germany., Lessing M; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, 24105, Kiel, Germany., Aden K; Institute of Clinical Molecular Biology, University Medical Center Schleswig-Holstein, Christian Albrecht University Kiel, Campus Kiel, Rosalind-Franklin-Strasse 12, 24105, Kiel, Germany.; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, 24105, Kiel, Germany., Lassen A; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, 24105, Kiel, Germany., Bergfeld A; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, 24105, Kiel, Germany., Weber HJ; Department of Gastroenterology, Asklepios Westklinikum, 22559, Hamburg, Germany.; Institute of Infection Medicine, University Medical Center Schleswig-Holstein, Christian Albrecht University Kiel, 24105, Kiel, Germany., Neas L; Department of Internal Medicine III, University Medical Center Schleswig-Holstein, 24105, Kiel, Germany., Vetrano S; Department of Biomedical Sciences, Humanitas University, 20072, Pieve Emanuele, Italy.; IBD Unit, Department of Gastroenterology, IRCCS Humanitas Research Hospital, 20089, Rozzano, Italy., Schreiber S; Institute of Clinical Molecular Biology, University Medical Center Schleswig-Holstein, Christian Albrecht University Kiel, Campus Kiel, Rosalind-Franklin-Strasse 12, 24105, Kiel, Germany.; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, 24105, Kiel, Germany., Rosenstiel P; Institute of Clinical Molecular Biology, University Medical Center Schleswig-Holstein, Christian Albrecht University Kiel, Campus Kiel, Rosalind-Franklin-Strasse 12, 24105, Kiel, Germany.

المصدر: Scientific reports [Sci Rep] 2024 May 13; Vol. 14 (1), pp. 10925. Date of Electronic Publication: 2024 May 13.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101563288 Publication Model: Electronic Cited Medium: Internet ISSN: 2045-2322 (Electronic) Linking ISSN: 20452322 NLM ISO Abbreviation: Sci Rep Subsets: MEDLINE

مواضيع طبية MeSH: MicroRNAs*/genetics , MicroRNAs*/metabolism , Extracellular Vesicles*/metabolism , Extracellular Vesicles*/genetics , Inflammatory Bowel Diseases*/genetics , Inflammatory Bowel Diseases*/metabolism , Inflammatory Bowel Diseases*/diagnostic imaging , Inflammatory Bowel Diseases*/pathology , Ultrasonography*/methods, Humans ; Male ; Female ; Adult ; Middle Aged ; Prospective Studies ; Biomarkers/metabolism

المؤلفون: Jiménez-Gracia L; Centro Nacional de Análisis Genómico (CNAG), 08028, Barcelona, Spain.; Universitat de Barcelona (UB), Barcelona, Spain., Marchese D; Centro Nacional de Análisis Genómico (CNAG), 08028, Barcelona, Spain.; Universitat de Barcelona (UB), Barcelona, Spain., Nieto JC; Centro Nacional de Análisis Genómico (CNAG), 08028, Barcelona, Spain.; Universitat de Barcelona (UB), Barcelona, Spain., Caratù G; Centro Nacional de Análisis Genómico (CNAG), 08028, Barcelona, Spain.; Universitat de Barcelona (UB), Barcelona, Spain., Melón-Ardanaz E; Inflammatory Bowel Disease Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Barcelona, Spain., Gudiño V; Inflammatory Bowel Disease Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Barcelona, Spain., Roth S; Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, Australia.; Monash University Department of Surgery, Alfred Hospital, Melbourne, VIC, Australia., Wise K; Adelaide Centre for Epigenetics (ACE), University of Adelaide, Adelaide, South Australia, Australia.; South Australian immunoGENomics Cancer Institute (SAiGENCI), University of Adelaide, Adelaide, South Australia, Australia.; Australian Genomics Research Facility, Adelaide, South Australia, Australia., Ryan NK; South Australian immunoGENomics Cancer Institute (SAiGENCI), University of Adelaide, Adelaide, South Australia, Australia.; Freemasons Foundation Centre for Men's Health, University of Adelaide, Adelaide, South Australia, Australia.; South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia., Jensen KB; Adelaide Centre for Epigenetics (ACE), University of Adelaide, Adelaide, South Australia, Australia.; South Australian immunoGENomics Cancer Institute (SAiGENCI), University of Adelaide, Adelaide, South Australia, Australia.; Australian Genomics Research Facility, Adelaide, South Australia, Australia., Hernando-Momblona X; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Barcelona, Spain., Bernardes JP; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany., Tran F; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany.; Department of Internal Medicine I, University Hospital Schleswig-Holstein (UKSH), Campus Kiel, Kiel, Germany., Sievers LK; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany.; Department of Internal Medicine I, University Hospital Schleswig-Holstein (UKSH), Campus Kiel, Kiel, Germany., Schreiber S; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany.; Department of Internal Medicine I, University Hospital Schleswig-Holstein (UKSH), Campus Kiel, Kiel, Germany., van den Berge M; Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.; Groningen Research Institute for Asthma and COPD, University of Groningen, University Medical Center Groningen, Groningen, Netherlands., Kole T; Department of Pulmonary Diseases, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.; Groningen Research Institute for Asthma and COPD, University of Groningen, University Medical Center Groningen, Groningen, Netherlands., van der Velde PL; Groningen Research Institute for Asthma and COPD, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.; Department of Pathology & Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands., Nawijn MC; Groningen Research Institute for Asthma and COPD, University of Groningen, University Medical Center Groningen, Groningen, Netherlands.; Department of Pathology & Medical Biology, University of Groningen, University Medical Center Groningen, Groningen, Netherlands., Rosenstiel P; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany., Batlle E; Institute for Research in Biomedicine (IRB Barcelona), The Barcelona Institute of Science and Technology, Barcelona, Spain.; Centro de Investigación Biomédica en Red de Cáncer (CIBERONC), Barcelona, Spain.; ICREA, Barcelona, Spain., Butler LM; South Australian immunoGENomics Cancer Institute (SAiGENCI), University of Adelaide, Adelaide, South Australia, Australia.; Freemasons Foundation Centre for Men's Health, University of Adelaide, Adelaide, South Australia, Australia.; South Australian Health and Medical Research Institute, Adelaide, South Australia, Australia., Parish IA; Cancer Immunology Program, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Melbourne, VIC, Australia., Plummer J; St Jude Children's Research Hospital, Memphis, TN, 38105, USA., Gut I; Centro Nacional de Análisis Genómico (CNAG), 08028, Barcelona, Spain.; Universitat de Barcelona (UB), Barcelona, Spain., Salas A; Inflammatory Bowel Disease Group, Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.; Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (CIBEREHD), Barcelona, Spain., Heyn H; Centro Nacional de Análisis Genómico (CNAG), 08028, Barcelona, Spain. holger.heyn@cnag.eu.; Universitat de Barcelona (UB), Barcelona, Spain. holger.heyn@cnag.eu.; Omniscope, Barcelona, Spain. holger.heyn@cnag.eu., Martelotto LG; Adelaide Centre for Epigenetics (ACE), University of Adelaide, Adelaide, South Australia, Australia. luciano.martelotto@adelaide.edu.au.; South Australian immunoGENomics Cancer Institute (SAiGENCI), University of Adelaide, Adelaide, South Australia, Australia. luciano.martelotto@adelaide.edu.au.; Omniscope, Barcelona, Spain. luciano.martelotto@adelaide.edu.au.

المصدر: Genome biology [Genome Biol] 2024 Mar 29; Vol. 25 (1), pp. 81. Date of Electronic Publication: 2024 Mar 29.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: BioMed Central Ltd Country of Publication: England NLM ID: 100960660 Publication Model: Electronic Cited Medium: Internet ISSN: 1474-760X (Electronic) Linking ISSN: 14747596 NLM ISO Abbreviation: Genome Biol Subsets: MEDLINE

مواضيع طبية MeSH: RNA*/genetics , Genomics*/methods, Humans ; Animals ; Mice ; Tissue Fixation/methods ; Reproducibility of Results ; Sequence Analysis, RNA/methods ; Single-Cell Analysis/methods

المؤلفون: Castrillón-Betancur JC; Institute of Clinical Molecular Biology, University of Kiel, Rosalind-Franklin-Straße 12, 24105 Kiel, Germany., López-Agudelo VA; Institute of Clinical Molecular Biology, University of Kiel, Rosalind-Franklin-Straße 12, 24105 Kiel, Germany., Sommer N; Institute of Clinical Molecular Biology, University of Kiel, Rosalind-Franklin-Straße 12, 24105 Kiel, Germany., Cleeves S; Fraunhofer Institute for Toxicology and Experimental Medicine ITEM, Nikolai-Fuchs-Straße 1, 30625 Hannover, Germany., Bernardes JP; Institute of Clinical Molecular Biology, University of Kiel, Rosalind-Franklin-Straße 12, 24105 Kiel, Germany., Weber-Stiehl S; Institute of Clinical Molecular Biology, University of Kiel, Rosalind-Franklin-Straße 12, 24105 Kiel, Germany., Rosenstiel P; Institute of Clinical Molecular Biology, University of Kiel, Rosalind-Franklin-Straße 12, 24105 Kiel, Germany., Sommer F; Institute of Clinical Molecular Biology, University of Kiel, Rosalind-Franklin-Straße 12, 24105 Kiel, Germany.

المصدر: Antioxidants (Basel, Switzerland) [Antioxidants (Basel)] 2023 Oct 21; Vol. 12 (10). Date of Electronic Publication: 2023 Oct 21.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI AG Country of Publication: Switzerland NLM ID: 101668981 Publication Model: Electronic Cited Medium: Print ISSN: 2076-3921 (Print) Linking ISSN: 20763921 NLM ISO Abbreviation: Antioxidants (Basel) Subsets: PubMed not MEDLINE

المؤلفون: Kunke M; Institute of Anatomy, Christian Albrechts-University Kiel, Kiel, Germany., Knöfler H; Institute of Anatomy, Christian Albrechts-University Kiel, Kiel, Germany., Dahlke E; Institute of Anatomy, Christian Albrechts-University Kiel, Kiel, Germany., Zanon Rodriguez L; Institute of Anatomy, Christian Albrechts-University Kiel, Kiel, Germany., Böttner M; Institute of Anatomy, Christian Albrechts-University Kiel, Kiel, Germany., Larionov A; Institute of Anatomy, Department of Medicine, University of Fribourg, Fribourg, Switzerland., Saudenova M; Institute of Anatomy, Christian Albrechts-University Kiel, Kiel, Germany., Ohrenschall GM; Institute of Anatomy, Christian Albrechts-University Kiel, Kiel, Germany., Westermann M; Institute of Anatomy, Christian Albrechts-University Kiel, Kiel, Germany., Porubsky S; Institute of Pathology, University of Mainz, Mainz, Germany., Bernardes JP; Department of Dermatology and Allergy, University Hospital Schleswig-Holstein, Kiel, Germany., Häsler R; Department of Dermatology and Allergy, University Hospital Schleswig-Holstein, Kiel, Germany., Magnin JL; Laboratoire HFR- Hôpital Cantonal, Fribourg, Switzerland., Koepsell H; Institute of Anatomy and Cell Biology, Julius-Maximilians-University of Würzburg, Würzburg, Germany., Jouret F; Groupe Interdisciplinaire de Génoprotéomique Appliquée (GIGA), Cardiovascular Sciences, University of Liège (ULiège), Liège, Belgium.; Division of Nephrology, CHU of Liège, University of Liège (CHU ULiège), Liège, Belgium., Theilig F; Institute of Anatomy, Christian Albrechts-University Kiel, Kiel, Germany. f.theilig@anat.uni-kiel.de.; Institute of Anatomy, Department of Medicine, University of Fribourg, Fribourg, Switzerland. f.theilig@anat.uni-kiel.de.

المصدر: Cell death & disease [Cell Death Dis] 2023 Aug 26; Vol. 14 (8), pp. 562. Date of Electronic Publication: 2023 Aug 26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101524092 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-4889 (Electronic) NLM ISO Abbreviation: Cell Death Dis Subsets: MEDLINE

مواضيع طبية MeSH: Diabetic Nephropathies*/genetics , Diabetes Mellitus, Type 1*/complications , Diabetes Mellitus, Type 1*/genetics , Diabetes Mellitus, Experimental*/complications , Diabetes Mellitus, Experimental*/genetics, Animals ; Mice ; Kidney ; Kidney Tubules, Proximal ; Kidney Glomerulus

المؤلفون: Tran F; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Kiel, Germany., Harris DMM; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.; Institute for Human Nutrition and Food Science, University Medical Center Schleswig-Holstein, Kiel, Germany., Scharmacher A; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany., Graßhoff H; Department of Rheumatology and Clinical Immunology, University Medical Center Schleswig-Holstein, Lübeck, Germany., Sterner K; Department of Rheumatology and Clinical Immunology, University Medical Center Schleswig-Holstein, Lübeck, Germany., Schinke S; Department of Rheumatology and Clinical Immunology, University Medical Center Schleswig-Holstein, Lübeck, Germany., Käding N; Department of Infectious Diseases and Microbiology, University Medical Center Schleswig-Holstein, Lübeck, Germany., Humrich JY; Department of Rheumatology and Clinical Immunology, University Medical Center Schleswig-Holstein, Lübeck, Germany., Cabral-Marques O; Department of Immunology, Instituto de Ciencias Biomedicas, Universidade de São Paulo, São Paulo, SP, Brazil.; Department of Clinical and Toxicological Analyses, School of Pharmaceutical Sciences, University of São Paulo, São Paulo, SP, Brazil.; Network of Immunity in Infection, Malignancy, and Autoimmunity, Universal Scientific Education and Research Network, Sao Paulo, SP, Brazil.; Department of Medicine, Division of Molecular Medicine, University of São Paulo School of Medicine, São Paulo, Brazil.; Laboratory of Medical Investigation 29, University of São Paulo School of Medicine, São Paulo, Brazil., Bernardes JP; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany., Mishra N; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany., Bahmer T; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Kiel, Germany.; LungenClinic Grosshansdorf, Airway Research Center North (ARCN), German Center for Lung Research (DZL), Grosshansdorf, Germany., Franzenburg J; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.; Institute of Clinical Chemistry, University Medical Center Schleswig-Holstein, Kiel, Germany., Hoyer BF; Section for Rheumatology, Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Kiel, Germany., Glück A; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Kiel, Germany., Guggeis M; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Kiel, Germany., Ossysek A; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany., Küller A; Department of Internal Medicine III, University Medical Center Schleswig-Holstein, Kiel, Germany., Frank D; Department of Internal Medicine III, University Medical Center Schleswig-Holstein, Kiel, Germany.; German Centre for Cardiovascular Research (DZHK), partner site Hamburg, Kiel, Lübeck, Germany., Lange C; Research Center Borstel, Borstel, Germany.; German Center for Infection Research (DZIF), Hamburg-Lübeck-Borstel-Riems, Borstel, Germany.; Respiratory Medicine and International Health, University of Lübeck, Lübeck, Germany.; Baylor College of Medicine and Texas Children's Hospital, Houston, TX, USA., Rupp J; Department of Infectious Diseases and Microbiology, University Medical Center Schleswig-Holstein, Lübeck, Germany., Heyckendorf J; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Kiel, Germany.; Research Center Borstel, Borstel, Germany.; German Center for Infection Research (DZIF), Hamburg-Lübeck-Borstel-Riems, Borstel, Germany.; Airway Research Center North (ARCN), Members of the German Center for Lung Research (DZL), Borstel, Germany., Gaede KI; Research Center Borstel, Borstel, Germany.; German Center for Infection Research (DZIF), Hamburg-Lübeck-Borstel-Riems, Borstel, Germany.; Airway Research Center North (ARCN), Members of the German Center for Lung Research (DZL), Borstel, Germany.; BioMaterialBank Nord, Borstel, Germany., Amital H; Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Ramat-Gan, Israel., Rosenstiel P; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany., Shoenfeld Y; Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Ramat-Gan, Israel.; Ariel University, Ariel, Israel.; Laboratory of the Mosaic of Autoimmunity, Saint Petersburg State University, Saint-Petersburg, Russia., Halpert G; Zabludowicz Center for Autoimmune Diseases, Sheba Medical Center, Ramat-Gan, Israel., Rosenberg AZ; Department of Pathology, Johns Hopkins University, Baltimore, MD, USA., Schulze-Forster K; CellTrend GmbH, Luckenwalde, Germany., Heidecke H; CellTrend GmbH, Luckenwalde, Germany., Riemekasten G; Institute for Human Nutrition and Food Science, University Medical Center Schleswig-Holstein, Kiel, Germany.; Priority Area Asthma and Allergy, Research Center Borstel, Airway Research Center North (ARCN), Members of the German Center for Lung Research (DZL), Borstel, Germany.; These authors contributed equally., Schreiber S; Institute of Clinical Molecular Biology, Christian-Albrechts-University Kiel and University Medical Center Schleswig-Holstein, Kiel, Germany.; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Kiel, Germany.; These authors contributed equally.

المصدر: ERJ open research [ERJ Open Res] 2022 Dec 27; Vol. 8 (4). Date of Electronic Publication: 2022 Dec 27 (Print Publication: 2022).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: European Respiratory Society Country of Publication: England NLM ID: 101671641 Publication Model: eCollection Cited Medium: Print ISSN: 2312-0541 (Print) Linking ISSN: 23120541 NLM ISO Abbreviation: ERJ Open Res Subsets: PubMed not MEDLINE

المؤلفون: Fazio A; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, 24105, Kiel, Germany., Bordoni D; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, 24105, Kiel, Germany., Kuiper JWP; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, 24105, Kiel, Germany., Weber-Stiehl S; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, 24105, Kiel, Germany., Stengel ST; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, 24105, Kiel, Germany., Arnold P; Institute of Functional and Clinical Anatomy, Friedrich-Alexander-University Erlangen-Nürnberg (FAU), 91058, Erlangen, Germany., Ellinghaus D; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, 24105, Kiel, Germany., Ito G; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, 24105, Kiel, Germany.; Advanced Research Institute, Tokyo Medical and Dental University, Tokyo, Japan., Tran F; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, 24105, Kiel, Germany.; Department of Internal Medicine I., Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, 24105, Kiel, Germany., Messner B; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, 24105, Kiel, Germany., Henning A; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, 24105, Kiel, Germany., Bernardes JP; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, 24105, Kiel, Germany., Häsler R; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, 24105, Kiel, Germany.; Department of Dermatology and Allergy, University Hospital Schleswig-Holstein, Campus Kiel, Kiel, Germany., Luzius A; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, 24105, Kiel, Germany., Imm S; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, 24105, Kiel, Germany., Hinrichsen F; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, 24105, Kiel, Germany., Franke A; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, 24105, Kiel, Germany., Huber S; I. Department of Medicine, University Medical Center Hamburg-Eppendorf, Hamburg, Germany., Nikolaus S; Department of Internal Medicine I., Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, 24105, Kiel, Germany., Aden K; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, 24105, Kiel, Germany.; Department of Internal Medicine I., Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, 24105, Kiel, Germany., Schreiber S; Department of Internal Medicine I., Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, 24105, Kiel, Germany., Sommer F; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, 24105, Kiel, Germany., Natoli G; Department of Experimental Oncology, European Institute of Oncology IRCCS (IEO), 20139, Milan, Italy., Mishra N; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, 24105, Kiel, Germany., Rosenstiel P; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Campus Kiel, 24105, Kiel, Germany. p.rosenstiel@mucosa.de.

المصدر: Nature communications [Nat Commun] 2022 Oct 21; Vol. 13 (1), pp. 6266. Date of Electronic Publication: 2022 Oct 21.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: DNA Methyltransferase 3A* , Inflammatory Bowel Diseases*/pathology, Humans ; Mice ; Animals ; Caco-2 Cells ; Intestinal Mucosa/metabolism ; Colon/pathology ; Epithelial Cells/metabolism ; Tumor Necrosis Factors/metabolism ; DNA/metabolism

المؤلفون: Formes H; Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, Langenbeckstrasse 1, 55131 Mainz, Germany.; Department of Chemistry, Biochemistry, Johannes Gutenberg-University Mainz, Hanns-Dieter-Hüsch-Weg 17, 55128 Mainz, Germany., Bernardes JP; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Medical Center Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany., Mann A; Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, Langenbeckstrasse 1, 55131 Mainz, Germany., Bayer F; Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, Langenbeckstrasse 1, 55131 Mainz, Germany., Pontarollo G; Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, Langenbeckstrasse 1, 55131 Mainz, Germany., Kiouptsi K; Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, Langenbeckstrasse 1, 55131 Mainz, Germany., Schäfer K; Department of Cardiology, Cardiology I, University Medical Center Mainz, Johannes Gutenberg-University Mainz, Langenbeckstrasse 1, 55131 Mainz, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Mainz, Germany., Attig S; Research Center for Immunotherapy (FZI), University Medical Center, Johannes Gutenberg-University Mainz, Langenbeckstrasse 1, 55131 Mainz, Germany.; TRON, Translational Oncology at the University Medical Center, Johannes Gutenberg-University Mainz gGmbH, Freiligrathstrasse 12, 55131 Mainz, Germany., Nikolova T; Institute of Toxicology, University Medical Center Mainz, Johannes Gutenberg-University Mainz, 55131 Mainz, Germany., Hofmann TG; Institute of Toxicology, University Medical Center Mainz, Johannes Gutenberg-University Mainz, 55131 Mainz, Germany., Schattenberg JM; Metabolic Liver Research Program, Department of Internal Medicine I, University Medical Center, Johannes Gutenberg University Mainz, Langenbeckstrasse 1, 55131 Mainz, Germany., Todorov H; Institute of Human Genetics, University Medical Center, Johannes Gutenberg-University Mainz, Langenbeckstrasse 1, 55131 Mainz, Germany., Gerber S; Institute of Human Genetics, University Medical Center, Johannes Gutenberg-University Mainz, Langenbeckstrasse 1, 55131 Mainz, Germany., Rosenstiel P; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Medical Center Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany., Bopp T; Research Center for Immunotherapy (FZI), University Medical Center, Johannes Gutenberg-University Mainz, Langenbeckstrasse 1, 55131 Mainz, Germany.; Institute for Immunology, University Medical Center Mainz, Johannes Gutenberg-University Mainz, Langenbeckstrasse 1, 55131 Mainz, Germany., Sommer F; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Medical Center Schleswig-Holstein, Campus Kiel, 24105 Kiel, Germany., Reinhardt C; Center for Thrombosis and Hemostasis (CTH), University Medical Center Mainz, Johannes Gutenberg-University Mainz, Langenbeckstrasse 1, 55131 Mainz, Germany.; German Center for Cardiovascular Research (DZHK), Partner Site Rhine-Main, Mainz, Germany.

المصدر: IScience [iScience] 2021 Sep 10; Vol. 24 (10), pp. 103092. Date of Electronic Publication: 2021 Sep 10 (Print Publication: 2021).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101724038 Publication Model: eCollection Cited Medium: Internet ISSN: 2589-0042 (Electronic) Linking ISSN: 25890042 NLM ISO Abbreviation: iScience Subsets: PubMed not MEDLINE

المؤلفون: Bernardes JP; Community Dynamics Group, Department of Evolutionary Ecology, Max Planck Institute for Evolutionary Biology, D-Plön, Germany.; Institute of Clinical Molecular Biology, Kiel University, Kiel, Germany., John U; Alfred Wegener Institute Helmholtz Centre for Polar and Marine Research, Bremerhaven, Germany.; Helmholtz Institute for Functional Marine Biodiversity, Oldenburg, Oldenburg, Germany., Woltermann N; Community Dynamics Group, Department of Evolutionary Ecology, Max Planck Institute for Evolutionary Biology, D-Plön, Germany., Valiadi M; Community Dynamics Group, Department of Evolutionary Ecology, Max Planck Institute for Evolutionary Biology, D-Plön, Germany.; Institute for Molecular Biology and Biotechnology, Foundation for Research and Technology Hellas, Heraklion, Crete, Greece., Hermann RJ; Limnological Institute University Konstanz, Aquatic Ecology and Evolution, Konstanz, Germany., Becks L; Community Dynamics Group, Department of Evolutionary Ecology, Max Planck Institute for Evolutionary Biology, D-Plön, Germany. lutz.becks@uni-konstanz.de.; Limnological Institute University Konstanz, Aquatic Ecology and Evolution, Konstanz, Germany. lutz.becks@uni-konstanz.de.

المصدر: Nature communications [Nat Commun] 2021 Jul 09; Vol. 12 (1), pp. 4222. Date of Electronic Publication: 2021 Jul 09.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101528555 Publication Model: Electronic Cited Medium: Internet ISSN: 2041-1723 (Electronic) Linking ISSN: 20411723 NLM ISO Abbreviation: Nat Commun Subsets: MEDLINE

مواضيع طبية MeSH: Biological Evolution* , Models, Biological*, Chlamydomonas reinhardtii/*physiology, Animals ; Cell Survival/physiology ; Predatory Behavior ; Rotifera/physiology

المؤلفون: Warnat-Herresthal S; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Schultze H; Hewlett Packard Enterprise, Houston, TX, USA., Shastry KL; Hewlett Packard Enterprise, Houston, TX, USA., Manamohan S; Hewlett Packard Enterprise, Houston, TX, USA., Mukherjee S; Hewlett Packard Enterprise, Houston, TX, USA., Garg V; Hewlett Packard Enterprise, Houston, TX, USA.; Mesh Dynamics, Bangalore, India., Sarveswara R; Hewlett Packard Enterprise, Houston, TX, USA., Händler K; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.; PRECISE Platform for Single Cell Genomics and Epigenomics, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE) and the University of Bonn, Bonn, Germany., Pickkers P; Department of Intensive Care Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands., Aziz NA; Population Health Sciences, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.; Department of Neurology, Faculty of Medicine, University of Bonn, Bonn, Germany., Ktena S; 4th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece., Tran F; Department of Internal Medicine I, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Kiel, Germany.; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Kiel, Germany., Bitzer M; Department of Internal Medicine I, University Hospital, University of Tübingen, Tübingen, Germany., Ossowski S; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany.; NGS Competence Center Tübingen, Tübingen, Germany., Casadei N; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany.; NGS Competence Center Tübingen, Tübingen, Germany., Herr C; Department of Internal Medicine V, Saarland University Hospital, Homburg, Germany., Petersheim D; Department of Pediatrics, Dr. von Hauner Children's Hospital, University Hospital LMU Munich, Munich, Germany., Behrends U; Children's Hospital, Medical Faculty, Technical University Munich, Munich, Germany., Kern F; Clinical Bioinformatics, Saarland University, Saarbrücken, Germany., Fehlmann T; Clinical Bioinformatics, Saarland University, Saarbrücken, Germany., Schommers P; Department I of Internal Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany., Lehmann C; Department I of Internal Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany., Augustin M; Department I of Internal Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany., Rybniker J; Department I of Internal Medicine, Faculty of Medicine and University Hospital of Cologne, University of Cologne, Cologne, Germany.; Center for Molecular Medicine Cologne (CMMC), University of Cologne, Cologne, Germany.; German Center for Infection Research (DZIF), Partner Site Bonn-Cologne, Cologne, Germany., Altmüller J; Cologne Center for Genomics, West German Genome Center, University of Cologne, Cologne, Germany., Mishra N; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Kiel, Germany., Bernardes JP; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Kiel, Germany., Krämer B; Clinical Infectious Diseases, Research Center Borstel and German Center for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, Borstel, Germany., Bonaguro L; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Schulte-Schrepping J; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., De Domenico E; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.; PRECISE Platform for Single Cell Genomics and Epigenomics, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE) and the University of Bonn, Bonn, Germany., Siever C; Hewlett Packard Enterprise, Houston, TX, USA., Kraut M; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.; PRECISE Platform for Single Cell Genomics and Epigenomics, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE) and the University of Bonn, Bonn, Germany., Desai M; Hewlett Packard Enterprise, Houston, TX, USA., Monnet B; Hewlett Packard Enterprise, Houston, TX, USA., Saridaki M; 4th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece., Siegel CM; Hewlett Packard Enterprise, Houston, TX, USA., Drews A; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.; PRECISE Platform for Single Cell Genomics and Epigenomics, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE) and the University of Bonn, Bonn, Germany., Nuesch-Germano M; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Theis H; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.; PRECISE Platform for Single Cell Genomics and Epigenomics, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE) and the University of Bonn, Bonn, Germany., Heyckendorf J; Clinical Infectious Diseases, Research Center Borstel and German Center for Infection Research (DZIF), Partner Site Hamburg-Lübeck-Borstel-Riems, Borstel, Germany., Schreiber S; Department of Internal Medicine I, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Kiel, Germany., Kim-Hellmuth S; Department of Pediatrics, Dr. von Hauner Children's Hospital, University Hospital LMU Munich, Munich, Germany., Nattermann J; Department of Internal Medicine I, University Hospital Bonn, Bonn, Germany.; German Center for Infection Research (DZIF), Braunschweig, Germany., Skowasch D; Department of Internal Medicine II - Cardiology/Pneumology, University of Bonn, Bonn, Germany., Kurth I; Institute of Human Genetics, Medical Faculty, RWTH Aachen University, Aachen, Germany., Keller A; Clinical Bioinformatics, Saarland University, Saarbrücken, Germany.; Department of Neurology and Neurological Sciences, Stanford University School of Medicine, Stanford, CA, USA., Bals R; Department of Internal Medicine V, Saarland University Hospital, Homburg, Germany., Nürnberg P; Cologne Center for Genomics, West German Genome Center, University of Cologne, Cologne, Germany., Rieß O; Institute of Medical Genetics and Applied Genomics, University of Tübingen, Tübingen, Germany.; NGS Competence Center Tübingen, Tübingen, Germany., Rosenstiel P; Institute of Clinical Molecular Biology, Christian-Albrechts-University and University Hospital Schleswig-Holstein, Kiel, Germany., Netea MG; Department of Internal Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands.; Immunology & Metabolism, Life and Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Theis F; Institute of Computational Biology, Helmholtz Center Munich (HMGU), Neuherberg, Germany., Mukherjee S; Statistics and Machine Learning, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany., Backes M; CISPA Helmholtz Center for Information Security, Saarbrücken, Germany., Aschenbrenner AC; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany.; PRECISE Platform for Single Cell Genomics and Epigenomics, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE) and the University of Bonn, Bonn, Germany.; Department of Internal Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands., Ulas T; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany., Breteler MMB; Population Health Sciences, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.; Institute for Medical Biometry, Informatics and Epidemiology (IMBIE), Faculty of Medicine, University of Bonn, Bonn, Germany., Giamarellos-Bourboulis EJ; 4th Department of Internal Medicine, National and Kapodistrian University of Athens, Medical School, Athens, Greece., Kox M; Department of Intensive Care Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands., Becker M; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany.; PRECISE Platform for Single Cell Genomics and Epigenomics, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE) and the University of Bonn, Bonn, Germany., Cheran S; Hewlett Packard Enterprise, Houston, TX, USA., Woodacre MS; Hewlett Packard Enterprise, Houston, TX, USA., Goh EL; Hewlett Packard Enterprise, Houston, TX, USA., Schultze JL; Systems Medicine, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE), Bonn, Germany. joachim.schultze@dzne.de.; Genomics and Immunoregulation, Life & Medical Sciences (LIMES) Institute, University of Bonn, Bonn, Germany. joachim.schultze@dzne.de.; PRECISE Platform for Single Cell Genomics and Epigenomics, Deutsches Zentrum für Neurodegenerative Erkrankungen (DZNE) and the University of Bonn, Bonn, Germany. joachim.schultze@dzne.de.

مؤلفون مشاركون: COVID-19 Aachen Study (COVAS), Deutsche COVID-19 Omics Initiative (DeCOI)

المصدر: Nature [Nature] 2021 Jun; Vol. 594 (7862), pp. 265-270. Date of Electronic Publication: 2021 May 26.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Blockchain* , Confidentiality* , Datasets as Topic* , Machine Learning*/trends, Clinical Decision-Making/*methods , Precision Medicine/*methods, COVID-19/diagnosis ; COVID-19/epidemiology ; Disease Outbreaks ; Female ; Humans ; Leukemia/diagnosis ; Leukemia/pathology ; Leukocytes/pathology ; Lung Diseases/diagnosis ; Male ; Software ; Tuberculosis/diagnosis

المؤلفون: Schreiber S; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany; Institute of Clinical Molecular Biology, Kiel University and University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany. Electronic address: s.schreiber@mucosa.de., Aden K; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany; Institute of Clinical Molecular Biology, Kiel University and University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany., Bernardes JP; Institute of Clinical Molecular Biology, Kiel University and University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany., Conrad C; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany., Tran F; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany; Institute of Clinical Molecular Biology, Kiel University and University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany., Höper H; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany., Volk V; Institute for Pathology, Medizinische Hochschule Hannover, Hannover, Germany., Mishra N; Institute of Clinical Molecular Biology, Kiel University and University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany., Blase JI; Institute of Clinical Molecular Biology, Kiel University and University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany., Nikolaus S; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany., Bethge J; Department of Internal Medicine I, University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany., Kühbacher T; Asklepios Westklinikum Hamburg, Hamburg, Germany., Röcken C; Department of Pathology, Kiel University and University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany., Chen M; The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China., Cottingham I; Ferring Pharmaceuticals A/S, Copenhagen S, Denmark., Petri N; Ferring Pharmaceuticals A/S, Copenhagen S, Denmark., Rasmussen BB; Ferring Pharmaceuticals A/S, Copenhagen S, Denmark., Lokau J; Department of Pathology, Otto-von-Guericke-University Magdeburg, Medical Faculty, Magdeburg, Germany., Lenk L; Department of Pediatrics I, Christian-Albrechts University Kiel and University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany., Garbers C; Department of Pathology, Otto-von-Guericke-University Magdeburg, Medical Faculty, Magdeburg, Germany., Feuerhake F; Institute for Pathology, Medizinische Hochschule Hannover, Hannover, Germany., Rose-John S; Institute of Biochemistry, Kiel University, Kiel, Germany., Waetzig GH; Institute of Clinical Molecular Biology, Kiel University and University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany; Conaris Research Institute AG, Kiel, Germany., Rosenstiel P; Institute of Clinical Molecular Biology, Kiel University and University Medical Center Schleswig-Holstein, Campus Kiel, Kiel, Germany. Electronic address: p.rosenstiel@mucosa.de.

المصدر: Gastroenterology [Gastroenterology] 2021 Jun; Vol. 160 (7), pp. 2354-2366.e11. Date of Electronic Publication: 2021 Mar 02.

نوع المنشور: Clinical Trial, Phase II; Journal Article; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: W.B. Saunders Country of Publication: United States NLM ID: 0374630 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1528-0012 (Electronic) Linking ISSN: 00165085 NLM ISO Abbreviation: Gastroenterology Subsets: MEDLINE

مواضيع طبية MeSH: Colitis, Ulcerative/*drug therapy , Crohn Disease/*drug therapy , Interleukin-6/*antagonists & inhibitors , Recombinant Fusion Proteins/*pharmacology , Signal Transduction/*drug effects, Adult ; Aged ; Colitis, Ulcerative/immunology ; Crohn Disease/immunology ; Female ; Humans ; Male ; Middle Aged ; Prospective Studies ; Receptors, Interleukin-6/metabolism ; Severity of Illness Index ; Treatment Outcome ; Young Adult