المؤلفون: Edwin Liu, Kristen McDaniel, Stephanie Case, Liping Yu, Bernd Gerhartz, Nils Ostermann, Gabriela Fankhauser, Valerie Hungerford, Chao Zou, Marcel Luyten, Katherine J. Seidl, Aaron W. Michels

المصدر: Autoimmune Diseases, Vol 2014 (2014)

مصطلحات موضوعية: Immunologic diseases. Allergy, RC581-607

وصف الملف: electronic resource

Relation: https://doaj.org/toc/2090-0422; https://doaj.org/toc/2090-0430

URL الوصول: https://doaj.org/article/3ed6788713dc4635b3bc81285e3b9baa

المؤلفون: Nello Mainolfi, Takeru Ehara, Rajeshri G. Karki, Karen Anderson, Aengus Mac Sweeney, Sha-Mei Liao, Upendra A. Argikar, Keith Jendza, Chun Zhang, James Powers, Daniel W. Klosowski, Maura Crowley, Toshio Kawanami, Jian Ding, Myriam April, Cornelia Forster, Michael Serrano-Wu, Michael Capparelli, Rrezarta Ramqaj, Catherine Solovay, Frederic Cumin, Thomas M. Smith, Luciana Ferrara, Wendy Lee, Debby Long, Melissa Prentiss, Andrea De Erkenez, Louis Yang, Fang Liu, Holger Sellner, Finton Sirockin, Eric Valeur, Paulus Erbel, Daniela Ostermeier, Paul Ramage, Bernd Gerhartz, Anna Schubart, Stefanie Flohr, Nathalie Gradoux, Roland Feifel, Barbara Vogg, Christian Wiesmann, Jürgen Maibaum, Jörg Eder, Richard Sedrani, Richard A. Harrison, Muneto Mogi, Bruce D. Jaffee, Christopher M. Adams

المصدر: Journal of Medicinal Chemistry. 63:5697-5722

مصطلحات موضوعية: Drug Discovery, Molecular Medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::161530bd60ced781537b4b5cf97869fc
https://doi.org/10.1021/acs.jmedchem.9b01870

المؤلفون: Paul Erbel, Bernd Gerhartz, Frederic Cumin, Jürgen Maibaum, Nils Ostermann, Edwige Lorthiois, Claudio Dalvit, Thomas Zoller, Stefan Andreas Randl, Simon Rüdisser, Ulrich Hommel, Anna Vulpetti, Aengus Mac Sweeney, Bahaa Salem

المصدر: Journal of Medicinal Chemistry. 60:1946-1958

مصطلحات موضوعية: 0301 basic medicine, Magnetic Resonance Spectroscopy, In silico, medicine.medical_treatment, 010402 general chemistry, 01 natural sciences, 03 medical and health sciences, Catalytic Domain, Complement Factor D, Drug Discovery, Hydrolase, medicine, Humans, Protease Inhibitors, Serine protease, Protease, Molecular Structure, biology, Chemistry, 0104 chemical sciences, Complement system, 030104 developmental biology, Biochemistry, Drug Design, biology.protein, Alternative complement pathway, Molecular Medicine, Factor D

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4cfc49de28df6dccc09e8711c747aed7
https://doi.org/10.1021/acs.jmedchem.6b01684

المؤلفون: Claus Ehrhardt, Takatoshi Kosaka, Jörg Trappe, Richard Sedrani, Bernd Gerhartz, Jürgen Maibaum, Simon Ruedisser, Sabine Geisse, Dean F. Rigel, Frederic Cumin, Johannes Ottl, Nils Ostermann, Trixie Wagner, Markus Krömer, Andreas Marzinzik, Eric Vangrevelinghe, Paul Richert, Edgar Jacoby, Martin Klumpp, Daniel K. Baeschlin, Eric Francotte, Randy L. Webb, J. Constanze D. Hartwieg, Werner Breitenstein, Ulrich Hassiepen

المصدر: Journal of Medicinal Chemistry. 56:2196-2206

مصطلحات موضوعية: Models, Molecular, Protein Conformation, Stereochemistry, Peptidomimetic, In silico, Administration, Oral, Biological Availability, Inhibitory Concentration 50, chemistry.chemical_compound, Piperidines, Renin, Drug Discovery, Animals, Protease Inhibitors, chemistry.chemical_classification, biology, Active site, Combinatorial chemistry, Rats, Enzyme, chemistry, Docking (molecular), Drug Design, biology.protein, Molecular Medicine, Piperidine, Pharmacophore, Tricyclic

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56536415f82cd33ef62b0ef099e5195e
https://doi.org/10.1021/jm301706j

المؤلفون: Frederic Cumin, Bernd Kinzel, Anna Vulpetti, Antonio M. Risitano, Richard A. Harrison, Kamal Fettis, Aengus Mac Sweeney, Stefan Andreas Randl, Edwige Lorthiois, Fabrice A. Kolb, Nils Ostermann, Solene Dussauge, Corinne Durand, Nicola Hughes, Bernd Gerhartz, Karen Anderson, Samuel Barbieri, Paul Erbel, Omar Delgado, Jörg Eder, Ulrich Hommel, Stefanie Flohr, Simon Rüdisser, Anna Schubart, Ty Gould, Bruce D Jaffee, Jürgen Maibaum, Julia Wagner, Sha-Mei Liao

المساهمون: Maibaum, Jürgen, Liao, Sha Mei, Vulpetti, Anna, Ostermann, Nil, Randl, Stefan, Rüdisser, Simon, Lorthiois, Edwige, Erbel, Paul, Kinzel, Bernd, Kolb, Fabrice A, Barbieri, Samuel, Wagner, Julia, Durand, Corinne, Fettis, Kamal, Dussauge, Solene, Hughes, Nicola, Delgado, Omar, Hommel, Ulrich, Gould, Ty, Sweeney, Aengus Mac, Gerhartz, Bernd, Cumin, Frederic, Flohr, Stefanie, Schubart, Anna, Jaffee, Bruce, Harrison, Richard, Risitano, ANTONIO MARIA, Eder, Jörg, Anderson, Karen

المصدر: Nature chemical biology. 12(12)

مصطلحات موضوعية: 0301 basic medicine, Lipopolysaccharides, Models, Molecular, medicine.medical_treatment, Complement Pathway, Alternative, Biology, Small Molecule Libraries, 03 medical and health sciences, Mice, Structure-Activity Relationship, 0302 clinical medicine, medicine, Animals, Humans, Enzyme Inhibitors, Molecular Biology, Protease, Innate immune system, Complement component 3, Dose-Response Relationship, Drug, Molecular Structure, Cell Biology, medicine.disease, Small molecule, Complement system, Cell biology, Mice, Inbred C57BL, 030104 developmental biology, 030220 oncology & carcinogenesis, Alternative complement pathway, Paroxysmal nocturnal hemoglobinuria, biology.protein, Factor D, Complement Factor D

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4d2c3a47759beca17b7b3f2b775e9551
https://pubmed.ncbi.nlm.nih.gov/27857140

المؤلفون: A. Hein, P. Erbel, S. Gil-Parrado, A. Bernardi, Ursula Bodendorf, D. Vinzenz, Bernd Gerhartz, C. Logel, A. Mac Sweeney

المصدر: Journal of Molecular Biology. 384:228-239

مصطلحات موضوعية: Models, Molecular, Proteases, Magnetic Resonance Spectroscopy, Tolloid-Like Metalloproteinases, medicine.medical_treatment, Molecular Sequence Data, Astacoidea, Crystallography, X-Ray, Bone morphogenetic protein, Protein Structure, Secondary, Bone morphogenetic protein 1, Bone Morphogenetic Protein 1, Substrate Specificity, Structural Biology, medicine, Animals, Humans, Amino Acid Sequence, Enzyme Inhibitors, Binding site, Molecular Biology, Metalloproteinase, Binding Sites, Protease, biology, Chemistry, Metalloendopeptidases, Active site, Protein Structure, Tertiary, Kinetics, Biochemistry, Bone Morphogenetic Proteins, Metalloproteases, biology.protein, Astacin, Sequence Alignment

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2816eaa06fe761b7b4f394fe149fad62
https://doi.org/10.1016/j.jmb.2008.09.029

المؤلفون: Marion Mahnke, Benoit Pierrat, Robert Mader, Tewis Bouwmeester, Bernd Gerhartz, Susanne Worpenberg, Jean-Marc Schlaeppi, Gerard Joberty, Amaury Ernesto Fernandez-Montalvan

المصدر: FEBS Journal. 274:4256-4270

مصطلحات موضوعية: Protease, biology, medicine.medical_treatment, Cell Biology, Subcellular localization, Biochemistry, Cysteine protease, Ubiquitin ligase, Deubiquitinating enzyme, Ubiquitin, medicine, biology.protein, Nuclear transport, Molecular Biology, Nuclear localization sequence

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d902de2aaf3a82202daebca27153be6a
https://doi.org/10.1111/j.1742-4658.2007.05952.x

المؤلفون: Silvio Roggo, Cecile Delmas, Nathalie Bürstner, Matthias Rottmann, Jason Murphy, Manuel Mihalic, Jutta Blank, Dominik Pistorius, Nils Ostermann, Dominic Hoepfner, Alexandra Hinniger, Brigitta Liechty, Esther K. Schmitt, Markus Schirle, Jason R. Thomas, Felix Freuler, Bernd Gerhartz

المصدر: Chembiochem : a European journal of chemical biology. 16(17)

مصطلحات موضوعية: medicine.medical_treatment, Plasmodium falciparum, Plasma protein binding, Molecular Dynamics Simulation, Biochemistry, Microbiology, Mycobacterium tuberculosis, chemistry.chemical_compound, Antimalarials, Inhibitory Concentration 50, Bacterial Proteins, Hydrolase, medicine, Humans, Binding site, Molecular Biology, Biological Products, Natural product, Protease, Binding Sites, biology, Organic Chemistry, Endopeptidase Clp, biology.organism_classification, medicine.disease, Acid Anhydride Hydrolases, Neoplasm Proteins, Protein Structure, Tertiary, chemistry, Molecular Medicine, Oligopeptides, Malaria, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dbe4dc9bff950984b0487cba0a3fa51d
https://pubmed.ncbi.nlm.nih.gov/26472355

المؤلفون: Ireos Filipuzzi, Johann Zimmermann, Johannes Ottl, Lukas Leder, Alain Schilb, Beate Leuenberger, Felix Freuler, Bernd Gerhartz, Virginie Riou, Aline Tirat, Ulf Eidhoff, Lorenz M. Mayr, Susanne Worpenberg, Thomas Stettler

المصدر: Analytical Biochemistry. 343:244-255

مصطلحات موضوعية: Time Factors, Lysine, Biophysics, Biology, Ubiquitin-conjugating enzyme, Biochemistry, Deubiquitinating enzyme, Ubiquitin, Endopeptidases, Molecular Biology, Chromatography, High Pressure Liquid, Fluorescent Dyes, chemistry.chemical_classification, Isopeptide bond, Rhodamines, Cell Biology, Fusion protein, Ubiquitin ligase, Kinetics, Enzyme, chemistry, biology.protein, Electrophoresis, Polyacrylamide Gel, Ubiquitin Thiolesterase

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f2a54e322618b6458d7fd23c329ea0b7
https://doi.org/10.1016/j.ab.2005.04.023

المؤلفون: David Ruiz-Carrillo, Hans-Ulrich Demuth, Steffen Roßner, Ulrike Zeitschel, Thomas Rudolph, Ingo Schulz, Volker Bigl, Bernd Gerhartz, Jens-Ulrich Rahfeld

المصدر: Journal of Neurochemistry. 94:970-979

مصطلحات موضوعية: education, Biology, Subcellular localization, Biochemistry, Fusion protein, Cellular and Molecular Neuroscience, Nocodazole, chemistry.chemical_compound, Tubulin, Prolyl endopeptidase, chemistry, cardiovascular system, biology.protein, medicine, Secretion, Cytoskeleton, Intracellular, circulatory and respiratory physiology, medicine.drug

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::58c0e4ed1e90fd0308feda0a905b5eae
https://doi.org/10.1111/j.1471-4159.2005.03237.x