المؤلفون: Davila KMS; Infectious Bacterial Disease Research Unit, National Animal Disease Center, United States Department of Agriculture, Agricultural Research Service, Ames, IA 50010, USA., Nelli RK; Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA., Mora-Díaz JC; Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA., Sang Y; Department of Agricultural and Environmental Sciences, College of Agriculture, Tennessee State University, Nashville, TN 37209, USA., Miller LC; Virus and Prion Research Unit, National Animal Disease Center, United States Department of Agriculture, Agricultural Research Service, Ames, IA 50010, USA.; Department of Diagnostic Medicine/Pathobiology, College of Veterinary Medicine, Kansas State University, Manhattan, KS 66506, USA., Giménez-Lirola LG; Department of Veterinary Diagnostic and Production Animal Medicine, College of Veterinary Medicine, Iowa State University, Ames, IA 50011, USA.

المصدر: Viruses [Viruses] 2024 Jun 11; Vol. 16 (6). Date of Electronic Publication: 2024 Jun 11.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Profiling* , Epithelial Cells*/virology , Epithelial Cells*/immunology , Interferons*/genetics , Interferons*/metabolism , Interferons*/immunology , Betacoronavirus 1*/immunology , Betacoronavirus 1*/genetics, Animals ; Swine ; Immunity, Innate ; Virus Replication ; Coronavirus Infections/immunology ; Coronavirus Infections/virology ; Coronavirus Infections/veterinary ; Cytokines/metabolism ; Cytokines/genetics ; Cytokines/immunology ; Transcriptome ; Respiratory Mucosa/virology ; Respiratory Mucosa/immunology ; Swine Diseases/virology ; Swine Diseases/immunology ; Swine Diseases/genetics ; Cells, Cultured ; Deltacoronavirus

SCR Organism: Porcine coronavirus HKU15

المؤلفون: Pusterla N; Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA, USA., Lawton K; Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA, USA., Barnum S; Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, CA, USA.

المصدر: The veterinary quarterly [Vet Q] 2024 Dec; Vol. 44 (1), pp. 1-6. Date of Electronic Publication: 2024 Mar 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Taylor & Francis Country of Publication: England NLM ID: 7909485 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1875-5941 (Electronic) Linking ISSN: 01652176 NLM ISO Abbreviation: Vet Q Subsets: MEDLINE

مواضيع طبية MeSH: Betacoronavirus 1* , Horse Diseases*/epidemiology , COVID-19*/epidemiology , COVID-19*/veterinary, Humans ; Horses ; Animals ; Female ; United States/epidemiology ; SARS-CoV-2 ; Seroepidemiologic Studies

المؤلفون: de Moura TR; Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw, ul. Ks. Trojdena 4, 02-109 Warsaw, Poland., Purta E; Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw, ul. Ks. Trojdena 4, 02-109 Warsaw, Poland., Bernat A; Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw, ul. Ks. Trojdena 4, 02-109 Warsaw, Poland., Martín-Cuevas EM; Department of Macromolecular Structures, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas, Madrid, Spain., Kurkowska M; Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw, ul. Ks. Trojdena 4, 02-109 Warsaw, Poland., Baulin EF; Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw, ul. Ks. Trojdena 4, 02-109 Warsaw, Poland., Mukherjee S; Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw, ul. Ks. Trojdena 4, 02-109 Warsaw, Poland., Nowak J; Malopolska Centre of Biotechnology, Jagiellonian University, Krakow, Poland., Biela AP; Malopolska Centre of Biotechnology, Jagiellonian University, Krakow, Poland., Rawski M; Malopolska Centre of Biotechnology, Jagiellonian University, Krakow, Poland.; National Synchrotron Radiation Centre SOLARIS, Jagiellonian University, Krakow, Poland., Glatt S; Malopolska Centre of Biotechnology, Jagiellonian University, Krakow, Poland., Moreno-Herrero F; Department of Macromolecular Structures, Centro Nacional de Biotecnología, Consejo Superior de Investigaciones Científicas, Madrid, Spain., Bujnicki JM; Laboratory of Bioinformatics and Protein Engineering, International Institute of Molecular and Cell Biology in Warsaw, ul. Ks. Trojdena 4, 02-109 Warsaw, Poland.

المصدر: Nucleic acids research [Nucleic Acids Res] 2024 Apr 12; Vol. 52 (6), pp. 3419-3432.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Oxford University Press Country of Publication: England NLM ID: 0411011 Publication Model: Print Cited Medium: Internet ISSN: 1362-4962 (Electronic) Linking ISSN: 03051048 NLM ISO Abbreviation: Nucleic Acids Res Subsets: MEDLINE

مواضيع طبية MeSH: Betacoronavirus*/genetics , RNA, Viral*/chemistry , RNA, Viral*/genetics , RNA, Viral*/ultrastructure, Cryoelectron Microscopy ; Genome, Viral/genetics ; SARS-CoV-2/genetics

المؤلفون: Zhou Q; Key Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China., Lan Y; Key Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China., Tang Y; Key Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China., Guan J; Key Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China., Zhao K; Key Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China., Gao F; Key Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China., He W; Key Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China., Li Z; Key Laboratory of Zoonosis Research, Ministry of Education, College of Veterinary Medicine, Jilin University, Changchun, China; Key Lab of Animal Production, Product Quality and Security, Ministry of Education, Jilin Agricultural University, Changchun, China. Electronic address: lizi1227@jlu.edu.cn.

المصدر: Veterinary microbiology [Vet Microbiol] 2022 Jun; Vol. 269, pp. 109448. Date of Electronic Publication: 2022 Apr 27.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Scientific Pub. Co Country of Publication: Netherlands NLM ID: 7705469 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1873-2542 (Electronic) Linking ISSN: 03781135 NLM ISO Abbreviation: Vet Microbiol Subsets: MEDLINE

مواضيع طبية MeSH: Betacoronavirus 1* , Coronavirus Infections*/veterinary , Swine Diseases*, Animals ; Betacoronavirus ; Microtubules ; Swine ; Tubulin/genetics ; Tubulin/metabolism ; Virus Replication

المؤلفون: Dolliver SM; Department of Microbiology and Immunology, Faculty of Medicine, Dalhousie University, Halifax, NS B3H 4R2, Canada., Galbraith C; Department of Microbiology and Immunology, Faculty of Medicine, Dalhousie University, Halifax, NS B3H 4R2, Canada., Khaperskyy DA; Department of Microbiology and Immunology, Faculty of Medicine, Dalhousie University, Halifax, NS B3H 4R2, Canada.

المصدر: Viruses [Viruses] 2024 Jan 31; Vol. 16 (2). Date of Electronic Publication: 2024 Jan 31.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: MDPI Country of Publication: Switzerland NLM ID: 101509722 Publication Model: Electronic Cited Medium: Internet ISSN: 1999-4915 (Electronic) Linking ISSN: 19994915 NLM ISO Abbreviation: Viruses Subsets: MEDLINE

مواضيع طبية MeSH: Betacoronavirus*/metabolism , Common Cold*, Humans ; Protein Phosphatase 1/metabolism ; Proteins/metabolism ; Phosphorylation ; Protein Biosynthesis ; Eukaryotic Initiation Factor-2/metabolism ; eIF-2 Kinase/genetics

المؤلفون: Pronker MF; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research, Department of Chemistry, Faculty of Science, Utrecht University, Utrecht, The Netherlands., Creutznacher R; Virology Section, Infectious Diseases and Immunology Division, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands., Drulyte I; Materials and Structural Analysis, Thermo Fisher Scientific, Eindhoven, The Netherlands., Hulswit RJG; Virology Section, Infectious Diseases and Immunology Division, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands., Li Z; Department of Chemical Biology and Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands., van Kuppeveld FJM; Virology Section, Infectious Diseases and Immunology Division, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands., Snijder J; Biomolecular Mass Spectrometry and Proteomics, Bijvoet Center for Biomolecular Research, Department of Chemistry, Faculty of Science, Utrecht University, Utrecht, The Netherlands., Lang Y; Virology Section, Infectious Diseases and Immunology Division, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands.; Research Center for Swine Diseases, College of Veterinary Medicine, Sichuan Agricultural University, Chengdu, China., Bosch BJ; Virology Section, Infectious Diseases and Immunology Division, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands., Boons GJ; Department of Chemical Biology and Drug Discovery, Utrecht Institute for Pharmaceutical Sciences, Utrecht University, Utrecht, The Netherlands., Frank M; Biognos AB, Gothenburg, Sweden., de Groot RJ; Virology Section, Infectious Diseases and Immunology Division, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands. r.j.degroot@uu.nl., Hurdiss DL; Virology Section, Infectious Diseases and Immunology Division, Department of Biomolecular Health Sciences, Faculty of Veterinary Medicine, Utrecht University, Utrecht, The Netherlands. d.l.hurdiss@uu.nl.

المصدر: Nature [Nature] 2023 Dec; Vol. 624 (7990), pp. 201-206. Date of Electronic Publication: 2023 Oct 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Betacoronavirus*/chemistry , Betacoronavirus*/ultrastructure , Polysaccharides*/chemistry , Polysaccharides*/metabolism , Sialic Acids*/chemistry , Sialic Acids*/metabolism , Spike Glycoprotein, Coronavirus*/chemistry , Spike Glycoprotein, Coronavirus*/metabolism , Spike Glycoprotein, Coronavirus*/ultrastructure, Humans ; Allosteric Regulation ; Common Cold/virology ; Cryoelectron Microscopy ; Molecular Dynamics Simulation ; Protein Binding ; Protein Conformation ; Immune Evasion

المؤلفون: Wang Z; State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, Jilin, China., He W; State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, Jilin, China., Li C; State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, Jilin, China., Chen Y; State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, Jilin, China., Li Z; State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, Jilin, China., Jiao Y; State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, Jilin, China., Zhang J; State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, Jilin, China., Shi J; State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, Jilin, China., Wang G; Jilin Academy of Animal Husbandry and Veterinary Medicine, Changchun, Jilin, China., Guan J; State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, Jilin, China., Zhao K; State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, Jilin, China., Song D; State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, Jilin, China., Gao F; State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, Jilin, China., Lan Y; State Key Laboratory for Diagnosis and Treatment of Severe Zoonotic Infectious Diseases, Key Laboratory for Zoonosis Research of the Ministry of Education, Institute of Zoonosis, and College of Veterinary Medicine, Jilin University, Changchun, Jilin, China.

المصدر: Journal of virology [J Virol] 2023 Dec 21; Vol. 97 (12), pp. e0133823. Date of Electronic Publication: 2023 Nov 27.

نوع المنشور: Comparative Study; Journal Article

بيانات الدورية: Publisher: American Society For Microbiology Country of Publication: United States NLM ID: 0113724 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1098-5514 (Electronic) Linking ISSN: 0022538X NLM ISO Abbreviation: J Virol Subsets: MEDLINE

مواضيع طبية MeSH: Betacoronavirus 1*/metabolism , Lysosomes*/enzymology , Lysosomes*/metabolism , Lysosomes*/virology , Neurons*/enzymology , Neurons*/metabolism , Neurons*/pathology , Neurons*/virology , Exocytosis* , Coronavirus Infections*/pathology , Coronavirus Infections*/transmission , Coronavirus Infections*/virology, Animals ; Mice ; Murine hepatitis virus/metabolism ; SARS-CoV-2/metabolism ; Swine/virology ; Hydrogen-Ion Concentration ; Vacuolar Proton-Translocating ATPases/metabolism

المؤلفون: Saunders N; Virus & Immunity Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France., Fernandez I; Structural Virology Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France., Planchais C; Humoral Immunology Unit, Institut Pasteur, Université de Paris Cité, INSERM U1222, Paris, France., Michel V; Pathogenesis of Vascular Infections Unit, Institut Pasteur, INSERM, Paris, France., Rajah MM; Virus & Immunity Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France., Baquero Salazar E; Nanoimaging core, Institut Pasteur, Université de Paris Cité, INSERM U1222, Paris, France., Postal J; Virus & Immunity Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France., Porrot F; Virus & Immunity Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France., Guivel-Benhassine F; Virus & Immunity Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France., Blanc C; Pasteur-TheraVectys Joint Lab, Institut Pasteur, Université de Paris Cité, Paris, France., Chauveau-Le Friec G; Antibody Engineering Platform, C2RT, Institut Pasteur, Université de Paris Cité, CNRS UMR 3528, Paris, France., Martin A; Virus & Immunity Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France., Grzelak L; Virus & Immunity Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France., Oktavia RM; Structural Virology Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France., Meola A; Structural Virology Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France., Ahouzi O; Structural Virology Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France., Hoover-Watson H; Virus & Immunity Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France., Prot M; G5 Evolutionary Genomics of RNA Viruses, Institut Pasteur, Paris, France., Delaune D; G5 Evolutionary Genomics of RNA Viruses, Institut Pasteur, Paris, France.; Institut de Recherche Biomédicale des Armées, Brétigny-sur-Orge, France., Cornelissen M; Department of Medical Microbiology and Infection Prevention, Amsterdam UMC, Molecular Diagnostic Unit, University of Amsterdam, Amsterdam, The Netherlands.; Amsterdam Institute for Infection and Immunity, Amsterdam, The Netherlands., Deijs M; Amsterdam Institute for Infection and Immunity, Amsterdam, The Netherlands.; Department of Medical Microbiology and Infection Prevention, Amsterdam UMC, Laboratory of Experimental Virology, University of Amsterdam, Amsterdam, The Netherlands., Meriaux V; Antibody Engineering Platform, C2RT, Institut Pasteur, Université de Paris Cité, CNRS UMR 3528, Paris, France., Mouquet H; Humoral Immunology Unit, Institut Pasteur, Université de Paris Cité, INSERM U1222, Paris, France., Simon-Lorière E; G5 Evolutionary Genomics of RNA Viruses, Institut Pasteur, Paris, France.; National Reference Center for viruses of respiratory infections, Institut Pasteur, Paris, France., van der Hoek L; Amsterdam Institute for Infection and Immunity, Amsterdam, The Netherlands.; Department of Medical Microbiology and Infection Prevention, Amsterdam UMC, Laboratory of Experimental Virology, University of Amsterdam, Amsterdam, The Netherlands., Lafaye P; Antibody Engineering Platform, C2RT, Institut Pasteur, Université de Paris Cité, CNRS UMR 3528, Paris, France., Rey F; Structural Virology Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France., Buchrieser J; Virus & Immunity Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France. julian.buchrieser@pasteur.fr., Schwartz O; Virus & Immunity Unit, Institut Pasteur, Université de Paris Cité, CNRS UMR 3569, Paris, France. olivier.schwartz@pasteur.fr.; Vaccine Research Institute, Creteil, France. olivier.schwartz@pasteur.fr.

المصدر: Nature [Nature] 2023 Dec; Vol. 624 (7990), pp. 207-214. Date of Electronic Publication: 2023 Oct 25.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 0410462 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-4687 (Electronic) Linking ISSN: 00280836 NLM ISO Abbreviation: Nature Subsets: MEDLINE

مواضيع طبية MeSH: Betacoronavirus*/metabolism , Receptors, Virus*/metabolism , Serine Endopeptidases*/metabolism , Spike Glycoprotein, Coronavirus*/metabolism, Humans ; Bronchi/cytology ; Bronchi/virology ; Common Cold/drug therapy ; Common Cold/virology ; Membrane Fusion ; SARS-CoV-2 ; Single-Domain Antibodies/pharmacology ; Single-Domain Antibodies/therapeutic use ; Species Specificity ; Virus Internalization

المؤلفون: Costacurta F; Institute of Virology, Medical University of Innsbruck, Innsbruck, Tyrol, Austria., Dodaro A; Molecular Modeling Section (MMS), Department of Pharmaceutical and Pharmacological Sciences, University of Padua, Padova, Italy., Bante D; Institute of Virology, Medical University of Innsbruck, Innsbruck, Tyrol, Austria., Schöppe H; Institute of Pharmacy/Pharmaceutical Chemistry and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innsbruck, Tyrol, Austria., Peng JY; Department of Infectious Diseases and Vaccines Research, MRL, Merck & Co., Inc., Rahway, New Jersey, United States of America., Sprenger B; Institute of Biochemistry and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innsbruck, Austria., He X; Department of Infectious Diseases and Vaccines Research, MRL, Merck & Co., Inc., Rahway, New Jersey, United States of America., Moghadasi SA; Department of Biochemistry, Molecular Biology and Biophysics, Institute for Molecular Virology, University of Minnesota, Minneapolis, Minnesota, United States of America., Egger LM; Institute of Molecular Biochemistry, Biocentre, Medical University of Innsbruck, Innsbruck, Austria., Fleischmann J; Institute of Molecular Biology, University of Innsbruck, Innsbruck, Tyrol, Austria.; Tyrolean Cancer Research Institute (TKFI), Innsbruck, Tyrol, Austria., Pavan M; Molecular Modeling Section (MMS), Department of Pharmaceutical and Pharmacological Sciences, University of Padua, Padova, Italy., Bassani D; Molecular Modeling Section (MMS), Department of Pharmaceutical and Pharmacological Sciences, University of Padua, Padova, Italy., Menin S; Molecular Modeling Section (MMS), Department of Pharmaceutical and Pharmacological Sciences, University of Padua, Padova, Italy., Rauch S; Institute of Virology, Medical University of Innsbruck, Innsbruck, Tyrol, Austria., Krismer L; Institute of Virology, Medical University of Innsbruck, Innsbruck, Tyrol, Austria., Sauerwein A; Institute of Virology, Medical University of Innsbruck, Innsbruck, Tyrol, Austria., Heberle A; Institute of Virology, Medical University of Innsbruck, Innsbruck, Tyrol, Austria., Rabensteiner T; Institute of Virology, Medical University of Innsbruck, Innsbruck, Tyrol, Austria., Ho J; Bioinformatics Institute, Agency for Science Technology and Research, Singapore, Singapore., Harris RS; Department of Biochemistry and Structural Biology, University of Texas Health San Antonio, San Antonio, Texas, United States of America.; Howard Hughes Medical Institute, University of Texas Health San Antonio, San Antonio, Texas, United States of America., Stefan E; Institute of Molecular Biology, University of Innsbruck, Innsbruck, Tyrol, Austria.; Tyrolean Cancer Research Institute (TKFI), Innsbruck, Tyrol, Austria., Schneider R; Institute of Biochemistry and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innsbruck, Austria., Dunzendorfer-Matt T; Institute of Molecular Biochemistry, Biocentre, Medical University of Innsbruck, Innsbruck, Austria., Naschberger A; Division of Biological and Environmental Sciences and Engineering (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia., Wang D; Department of Infectious Diseases and Vaccines Research, MRL, Merck & Co., Inc., Rahway, New Jersey, United States of America., Kaserer T; Institute of Pharmacy/Pharmaceutical Chemistry and Center for Molecular Biosciences Innsbruck (CMBI), University of Innsbruck, Innsbruck, Tyrol, Austria., Moro S; Molecular Modeling Section (MMS), Department of Pharmaceutical and Pharmacological Sciences, University of Padua, Padova, Italy., von Laer D; Institute of Virology, Medical University of Innsbruck, Innsbruck, Tyrol, Austria., Heilmann E; Institute of Virology, Medical University of Innsbruck, Innsbruck, Tyrol, Austria.; Division of Biological and Environmental Sciences and Engineering (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, Saudi Arabia.

المصدر: PLoS pathogens [PLoS Pathog] 2024 Sep 11; Vol. 20 (9), pp. e1012522. Date of Electronic Publication: 2024 Sep 11 (Print Publication: 2024).

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Public Library of Science Country of Publication: United States NLM ID: 101238921 Publication Model: eCollection Cited Medium: Internet ISSN: 1553-7374 (Electronic) Linking ISSN: 15537366 NLM ISO Abbreviation: PLoS Pathog Subsets: MEDLINE

مواضيع طبية MeSH: SARS-CoV-2*/genetics , SARS-CoV-2*/drug effects , Drug Resistance, Viral*/genetics , Protease Inhibitors*/pharmacology , Mutation* , Coronavirus 3C Proteases*/genetics , Coronavirus 3C Proteases*/antagonists & inhibitors , Coronavirus 3C Proteases*/metabolism , Antiviral Agents*/pharmacology, Humans ; COVID-19/virology ; Leucine/analogs & derivatives ; Leucine/genetics ; Leucine/pharmacology ; Animals ; Betacoronavirus/genetics ; Betacoronavirus/drug effects ; Vesiculovirus/genetics ; Vesiculovirus/drug effects ; COVID-19 Drug Treatment ; Lactams ; Nitriles ; Proline

SCR Organism: SARS-CoV-2 variants

المؤلفون: Jiang H; School of Basic Medical Sciences, Jiangxi Medical College, Nanchang University, Nanchang 330031, China., Li W; College of Pharmaceutical Sciences, Gannan Medical University, Ganzhou 341000, China., Zhou X; College of Pharmaceutical Sciences, Gannan Medical University, Ganzhou 341000, China., Zhang J; School of Basic Medical Sciences, Jiangxi Medical College, Nanchang University, Nanchang 330031, China., Li J; College of Pharmaceutical Sciences, Gannan Medical University, Ganzhou 341000, China. Electronic address: rmsl_2040@163.com.

المصدر: International journal of biological macromolecules [Int J Biol Macromol] 2024 Sep; Vol. 276 (Pt 1), pp. 133706. Date of Electronic Publication: 2024 Jul 07.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Elsevier Country of Publication: Netherlands NLM ID: 7909578 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0003 (Electronic) Linking ISSN: 01418130 NLM ISO Abbreviation: Int J Biol Macromol Subsets: MEDLINE

مواضيع طبية MeSH: SARS-CoV-2*/enzymology , SARS-CoV-2*/drug effects , Molecular Dynamics Simulation* , Coronavirus 3C Proteases*/antagonists & inhibitors , Coronavirus 3C Proteases*/chemistry , Coronavirus 3C Proteases*/metabolism, Crystallography, X-Ray ; Antiviral Agents/chemistry ; Antiviral Agents/pharmacology ; Humans ; Protein Binding ; Protease Inhibitors/chemistry ; Protease Inhibitors/pharmacology ; COVID-19/virology ; Severe acute respiratory syndrome-related coronavirus/enzymology ; Betacoronavirus/enzymology ; Betacoronavirus/drug effects ; Middle East Respiratory Syndrome Coronavirus/enzymology ; Middle East Respiratory Syndrome Coronavirus/drug effects ; Cysteine Endopeptidases/chemistry ; Cysteine Endopeptidases/metabolism ; Viral Nonstructural Proteins/chemistry ; Viral Nonstructural Proteins/antagonists & inhibitors ; Viral Nonstructural Proteins/metabolism ; Binding Sites ; Coronavirus Infections/virology ; Coronavirus Infections/drug therapy ; Pandemics ; Pneumonia, Viral/virology ; Pneumonia, Viral/drug therapy