المؤلفون: Joel Quispe, David Veesler, Philip Bradley, Scott E. Boyken, David Baker, Una Nattermann, William Sheffler, D. Nagarajan, George Ueda, Alexis Courbet, Young-Jun Park, Justin M. Kollman, J. P. Hansen, Bethel Np, Daniel-Adriano Silva, Adam Moyer, Chunfu Xu, Yang Hsia, Neil P. King

مصطلحات موضوعية: Physics, Mechanical system, Degrees of freedom, Protein design, Energy landscape, Computational design, Biological system, Rotation (mathematics), Nanoscopic scale, Symmetry (physics)

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::d1980c347129ed6f10ca632fa616b536
https://doi.org/10.1101/2021.11.11.468255

المؤلفون: Pamela A. Silver, Thadani Nn, Roger L. Chang, David Baker, Mike T. Veling, Jeffrey C. Way, Bethel Np, Oster Me, Nguyen Dt, Nathanael J. Rollins, Kelly P Brock, Debora S. Marks

مصطلحات موضوعية: Synthetic protein, Downregulation and upregulation, Chemistry, Apoptosis, Intrinsically disordered proteins, Cell biology

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::17a46f0161144e3d2f717b097c45156b
https://doi.org/10.1101/2021.10.01.462432

المؤلفون: Shen H; Department of Biochemistry, University of Washington, Seattle, WA, USA. shenh2@uw.edu.; Institute for Protein Design, University of Washington, Seattle, WA, USA. shenh2@uw.edu., Lynch EM; Department of Biochemistry, University of Washington, Seattle, WA, USA., Akkineni S; Department of Materials Science and Engineering, University of Washington, Seattle, WA, USA.; Physical Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA., Watson JL; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA.; MRC Laboratory of Molecular Biology, Cambridge, UK., Decarreau J; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Bethel NP; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Benna I; Institute for Protein Design, University of Washington, Seattle, WA, USA.; Department of Bioengineering, University of Washington, Seattle, WA, USA., Sheffler W; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Farrell D; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., DiMaio F; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Derivery E; MRC Laboratory of Molecular Biology, Cambridge, UK., De Yoreo JJ; Department of Materials Science and Engineering, University of Washington, Seattle, WA, USA.; Physical Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA., Kollman J; Department of Biochemistry, University of Washington, Seattle, WA, USA., Baker D; Department of Biochemistry, University of Washington, Seattle, WA, USA. dabaker@uw.edu.; Institute for Protein Design, University of Washington, Seattle, WA, USA. dabaker@uw.edu.; Howard Hughes Medical Institute, University of Washington, Seattle, WA, USA. dabaker@uw.edu.

المصدر: Nature nanotechnology [Nat Nanotechnol] 2024 Jul; Vol. 19 (7), pp. 1016-1021. Date of Electronic Publication: 2024 Apr 03.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101283273 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1748-3395 (Electronic) Linking ISSN: 17483387 NLM ISO Abbreviation: Nat Nanotechnol Subsets: MEDLINE

مواضيع طبية MeSH: Histidine*/chemistry, Hydrogen-Ion Concentration ; Proteins/chemistry ; Nanostructures/chemistry ; Models, Molecular ; Hydrogen Bonding ; Cryoelectron Microscopy

المؤلفون: Bethel NP; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA.; Howard Hughes Medical Institute, University of Washington, Seattle, WA, USA., Borst AJ; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Parmeggiani F; School of Chemistry, University of Bristol, Bristol, UK.; School of Biochemistry, University of Bristol, Bristol, UK.; Bristol Biodesign Institute, University of Bristol, Bristol, UK., Bick MJ; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Brunette TJ; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Nguyen H; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Kang A; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Bera AK; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Carter L; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Miranda MC; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Kibler RD; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Lamb M; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Li X; Department of Biochemistry, University of Washington, Seattle, WA, USA.; Institute for Protein Design, University of Washington, Seattle, WA, USA., Sankaran B; Berkeley Center for Structural Biology, Molecular Biophysics and Integrated Bioimaging, Lawrence Berkeley Laboratory, Berkeley, CA, USA., Baker D; Department of Biochemistry, University of Washington, Seattle, WA, USA. dabaker@uw.edu.; Institute for Protein Design, University of Washington, Seattle, WA, USA. dabaker@uw.edu.; Howard Hughes Medical Institute, University of Washington, Seattle, WA, USA. dabaker@uw.edu.

المصدر: Nature chemistry [Nat Chem] 2023 Dec; Vol. 15 (12), pp. 1664-1671. Date of Electronic Publication: 2023 Sep 04.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 101499734 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1755-4349 (Electronic) Linking ISSN: 17554330 NLM ISO Abbreviation: Nat Chem Subsets: MEDLINE

مواضيع طبية MeSH: Nanofibers*, Models, Molecular ; Protein Conformation, alpha-Helical ; Protein Subunits

المؤلفون: Khmelinskaia A, Bethel NP, Fatehi F, Antanasijevic A, Borst AJ, Lai SH, Wang JYJ, Mallik BB, Miranda MC, Watkins AM, Ogohara C, Caldwell S, Wu M, Heck AJR, Veesler D, Ward AB, Baker D, Twarock R, King NP

المصدر: BioRxiv : the preprint server for biology [bioRxiv] 2023 Oct 19. Date of Electronic Publication: 2023 Oct 19.

نوع المنشور: Preprint

بيانات الدورية: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE

المؤلفون: Veling MT; Department of Systems Biology, Harvard Medical School, Boston, Massachusetts 02115, United States.; Wyss Institute for Biologically Inspired Engineering, Boston, Massachusetts 02115, United States., Nguyen DT; Department of Systems Biology, Harvard Medical School, Boston, Massachusetts 02115, United States.; Wyss Institute for Biologically Inspired Engineering, Boston, Massachusetts 02115, United States., Thadani NN; Department of Systems Biology, Harvard Medical School, Boston, Massachusetts 02115, United States., Oster ME; Department of Systems Biology, Harvard Medical School, Boston, Massachusetts 02115, United States.; Wyss Institute for Biologically Inspired Engineering, Boston, Massachusetts 02115, United States., Rollins NJ; Department of Systems Biology, Harvard Medical School, Boston, Massachusetts 02115, United States.; Wyss Institute for Biologically Inspired Engineering, Boston, Massachusetts 02115, United States., Brock KP; Department of Systems Biology, Harvard Medical School, Boston, Massachusetts 02115, United States., Bethel NP; Institute for Protein Design, University of Washington, Seattle, Washington 98195, United States.; Department of Biochemistry, University of Washington, Seattle, Washington 98195, United States., Lim S; Department of Systems Biology, Harvard Medical School, Boston, Massachusetts 02115, United States.; Wyss Institute for Biologically Inspired Engineering, Boston, Massachusetts 02115, United States., Baker D; Institute for Protein Design, University of Washington, Seattle, Washington 98195, United States.; Department of Biochemistry, University of Washington, Seattle, Washington 98195, United States.; Howard Hughes Medical Institute, University of Washington, Seattle, Washington 98195, United States., Way JC; Department of Systems Biology, Harvard Medical School, Boston, Massachusetts 02115, United States.; Wyss Institute for Biologically Inspired Engineering, Boston, Massachusetts 02115, United States., Marks DS; Department of Systems Biology, Harvard Medical School, Boston, Massachusetts 02115, United States.; Broad Institute of Harvard and MIT, Cambridge, Massachusetts 02142, United States., Chang RL; Department of Systems Biology, Harvard Medical School, Boston, Massachusetts 02115, United States.; Wyss Institute for Biologically Inspired Engineering, Boston, Massachusetts 02115, United States.; Department of Systems & Computational Biology, Albert Einstein College of Medicine, Bronx, New York 10461, United States., Silver PA; Department of Systems Biology, Harvard Medical School, Boston, Massachusetts 02115, United States.; Wyss Institute for Biologically Inspired Engineering, Boston, Massachusetts 02115, United States.

المصدر: ACS synthetic biology [ACS Synth Biol] 2022 Mar 18; Vol. 11 (3), pp. 1292-1302. Date of Electronic Publication: 2022 Feb 18.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101575075 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2161-5063 (Electronic) Linking ISSN: 21615063 NLM ISO Abbreviation: ACS Synth Biol Subsets: MEDLINE

مواضيع طبية MeSH: Intrinsically Disordered Proteins*/chemistry , Intrinsically Disordered Proteins*/metabolism , Tardigrada*/metabolism, Animals ; Apoptosis ; Humans

المؤلفون: Argudo D; Cardiovascular Research Institute, Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA., Capponi S; Cardiovascular Research Institute, Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA., Bethel NP; Cardiovascular Research Institute, Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA., Grabe M; Cardiovascular Research Institute, Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA michael.grabe@ucsf.edu.

المصدر: The Journal of general physiology [J Gen Physiol] 2019 Mar 04; Vol. 151 (3), pp. 316-327. Date of Electronic Publication: 2019 Feb 06.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Rockefeller University Press Country of Publication: United States NLM ID: 2985110R Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1540-7748 (Electronic) Linking ISSN: 00221295 NLM ISO Abbreviation: J Gen Physiol Subsets: MEDLINE

مواضيع طبية MeSH: Mechanotransduction, Cellular*, Ankyrins/*chemistry , Drosophila Proteins/*chemistry , Transient Receptor Potential Channels/*chemistry, Animals ; Ankyrins/metabolism ; Binding Sites ; Drosophila ; Drosophila Proteins/metabolism ; Ion Channel Gating ; Molecular Dynamics Simulation ; Protein Binding ; Transient Receptor Potential Channels/metabolism

المؤلفون: Han TW; Howard Hughes Medical Institute, University of California, San Francisco, CA 94143.; Department of Physiology, University of California, San Francisco, CA 94143.; Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94143., Ye W; Howard Hughes Medical Institute, University of California, San Francisco, CA 94143.; Department of Physiology, University of California, San Francisco, CA 94143.; Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94143., Bethel NP; Department of Pharmaceutical Chemistry, Cardiovascular Research Institute, University of California, San Francisco, CA 94143., Zubia M; Howard Hughes Medical Institute, University of California, San Francisco, CA 94143.; Department of Physiology, University of California, San Francisco, CA 94143.; Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94143., Kim A; Howard Hughes Medical Institute, University of California, San Francisco, CA 94143.; Department of Physiology, University of California, San Francisco, CA 94143.; Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94143., Li KH; Mass Spectrometry Facility, University of California, San Francisco, CA 94143., Burlingame AL; Mass Spectrometry Facility, University of California, San Francisco, CA 94143., Grabe M; Department of Pharmaceutical Chemistry, Cardiovascular Research Institute, University of California, San Francisco, CA 94143., Jan YN; Howard Hughes Medical Institute, University of California, San Francisco, CA 94143.; Department of Physiology, University of California, San Francisco, CA 94143.; Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94143., Jan LY; Howard Hughes Medical Institute, University of California, San Francisco, CA 94143; Lily.Jan@ucsf.edu.; Department of Physiology, University of California, San Francisco, CA 94143.; Department of Biochemistry and Biophysics, University of California, San Francisco, CA 94143.

المصدر: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2019 Jan 22; Vol. 116 (4), pp. 1309-1318. Date of Electronic Publication: 2019 Jan 08.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE

مواضيع طبية MeSH: Anoctamins/*metabolism , Biological Transport/*physiology , Phospholipid Transfer Proteins/*metabolism, Animals ; Calcium/metabolism ; Cell Line ; Cell Line, Tumor ; Cell Membrane/metabolism ; Cell-Derived Microparticles/metabolism ; Extracellular Vesicles/metabolism ; HEK293 Cells ; Humans ; Mice ; Phospholipids/metabolism

المؤلفون: Peters CJ; Departments of Physiology, Biophysics and Biochemistry, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address: christian.peters@ucsf.edu., Gilchrist JM; Departments of Physiology, Biophysics and Biochemistry, University of California, San Francisco, San Francisco, CA 94158, USA., Tien J; Departments of Physiology, Biophysics and Biochemistry, University of California, San Francisco, San Francisco, CA 94158, USA., Bethel NP; Department of Pharmaceutical Chemistry and Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 94158, USA., Qi L; Departments of Physiology, Biophysics and Biochemistry, University of California, San Francisco, San Francisco, CA 94158, USA., Chen T; Departments of Physiology, Biophysics and Biochemistry, University of California, San Francisco, San Francisco, CA 94158, USA., Wang L; Departments of Physiology, Biophysics and Biochemistry, University of California, San Francisco, San Francisco, CA 94158, USA., Jan YN; Departments of Physiology, Biophysics and Biochemistry, University of California, San Francisco, San Francisco, CA 94158, USA; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA 94158, USA., Grabe M; Department of Pharmaceutical Chemistry and Cardiovascular Research Institute, University of California, San Francisco, San Francisco, CA 94158, USA., Jan LY; Departments of Physiology, Biophysics and Biochemistry, University of California, San Francisco, San Francisco, CA 94158, USA; Howard Hughes Medical Institute, University of California, San Francisco, San Francisco, CA 94158, USA. Electronic address: lily.jan@ucsf.edu.

المصدر: Neuron [Neuron] 2018 Mar 07; Vol. 97 (5), pp. 1063-1077.e4. Date of Electronic Publication: 2018 Feb 22.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 8809320 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-4199 (Electronic) Linking ISSN: 08966273 NLM ISO Abbreviation: Neuron Subsets: MEDLINE

مواضيع طبية MeSH: Anoctamin-1/*chemistry , Anoctamin-1/*metabolism , Chloride Channels/*chemistry , Chloride Channels/*metabolism , Ion Channel Gating/*physiology, Amino Acid Sequence ; Animals ; Anoctamin-1/genetics ; Chloride Channels/genetics ; HEK293 Cells ; Humans ; Mice ; Protein Binding/physiology ; Protein Structure, Secondary

المؤلفون: Guerriero CJ; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260., Reutter KR; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260., Augustine AA; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260., Preston GM; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260., Weiberth KF; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260., Mackie TD; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260., Cleveland-Rubeor HC; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260., Bethel NP; Cardiovascular Research Institute, Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 94158., Callenberg KM; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260., Nakatsukasa K; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260.; Division of Biological Science, Graduate School of Natural Sciences, Nagoya City University, Nagoya, Aichi 467-8501, Japan., Grabe M; Cardiovascular Research Institute, Department of Pharmaceutical Chemistry, University of California, San Francisco, San Francisco, CA 94158., Brodsky JL; Department of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260 jbrodsky@pitt.edu.

المصدر: Molecular biology of the cell [Mol Biol Cell] 2017 Jul 15; Vol. 28 (15), pp. 2076-2090. Date of Electronic Publication: 2017 May 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Society for Cell Biology Country of Publication: United States NLM ID: 9201390 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1939-4586 (Electronic) Linking ISSN: 10591524 NLM ISO Abbreviation: Mol Biol Cell Subsets: MEDLINE

مواضيع طبية MeSH: Endoplasmic Reticulum-Associated Degradation/*physiology , Membrane Proteins/*metabolism, Adenosine Triphosphatases/metabolism ; Cell Cycle Proteins/metabolism ; Endoplasmic Reticulum/metabolism ; Hydrophobic and Hydrophilic Interactions ; Membranes/metabolism ; Mutation ; Proteasome Endopeptidase Complex/metabolism ; Protein Folding ; Protein Translocation Systems/metabolism ; Protein Transport ; Saccharomyces cerevisiae/metabolism ; Saccharomyces cerevisiae Proteins/metabolism ; Ubiquitin/metabolism ; Ubiquitin-Protein Ligases/metabolism ; Ubiquitination