المؤلفون: Diogo, D, Bastarache, L, Liao, KP, Graham, RR, Fulton, RS, Greenberg, JD, Eyre, S, Bowes, J, Cui, J, Lee, A, Pappas, DA, Kremer, JM, Barton, A, Coenen, MJH, Franke, B, Kiemeney, LA, Mariette, X, Richard-Miceli, C, Canhao, H, Fonseca, JE, de Vries, N, Tak, PP, Crusius, JBA, Nurmohamed, MT, Kurreeman, F, Mikuls, TR, Okada, Y, Stahl, EA, Larson, DE, Deluca, TL, O'Laughlin, M, Fronick, CC, Fulton, LL, Kosoy, R, Ransom, M, Bhangale, TR, Ortmann, W, Cagan, A, Gainer, V, Karlson, EW, Kohane, I, Murphy, SN, Martin, J, Zhernakova, A, Klareskog, L, Padyukov, L, Worthington, J, Mardis, ER, Seldin, MF, Gregersen, PK, Behrens, T, Raychaudhuri, S, Denny, JC, Plenge, RM

المصدر: PloS one. 10(4):e0122271

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:131098005

المؤلفون: Quinn, JP, Billingsley, Kimberley, Chang, D, Nalls, MA, Hallgrímsdóttir, IB, Hunkapiller, J, van der Brug, M, Cai, F, International Parkinson's Disease Genomics Consortium, 23andMe Research Team, Kerchner, GA, Ayalon, G, Bingol, B, Sheng, M, Hinds, D, Behrens, TW, Singleton, AB, Bhangale, TR, Graham, RR

المصدر: Nature Genetics

مصطلحات موضوعية: 0301 basic medicine, Risk, Linkage disequilibrium, Genome-wide association study, Disease, Biology, Quantitative trait locus, Article, Linkage Disequilibrium, Antiparkinson Agents, 03 medical and health sciences, 0302 clinical medicine, Genetics, Autophagy, Humans, Genetic Predisposition to Disease, Molecular Targeted Therapy, Gene, Genetic association, Case-control study, Parkinson Disease, 030104 developmental biology, Genetic Loci, Meta-analysis, Case-Control Studies, Lysosomes, 030217 neurology & neurosurgery, Genome-Wide Association Study, Transcription Factors

وصف الملف: application/pdf

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cff1aad164e898978a1abe06749892d6

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المؤلفون: Bronson, PG, Manoharan, AP, Bhangale, TR, Ortmann, W, Ferreira, RC, Pan-Hammerstrom, Q, Hammerstrom, L, Graham, RR, Behrens, TW

المصدر: TISSUE ANTIGENS. 79(6):413-414

مصطلحات موضوعية: Medicin och hälsovetenskap

URL الوصول: http://kipublications.ki.se/Default.aspx?queryparsed=id:124557772

المؤلفون: Haug-Baltzell A; Genetics Interdisciplinary Group, University of Arizona, Tucson, AZ, 85719, USA.; Department of Human Genetics, Genentech Inc, South San Francisco, 94080, CA, USA., Bhangale TR; Department of Human Genetics, Genentech Inc, South San Francisco, 94080, CA, USA.; Department of Bioinformatics and Computational Biology, Genentech Inc, South San Francisco, 94080, CA, USA., Chang D; Department of Human Genetics, Genentech Inc, South San Francisco, 94080, CA, USA., Dressen A; Department of Human Genetics, Genentech Inc, South San Francisco, 94080, CA, USA., Yaspan BL; Department of Human Genetics, Genentech Inc, South San Francisco, 94080, CA, USA., Ortmann W; Biosample and Depository Management, Genentech Inc, South San Francisco, CA, 94080, USA., Brauer MJ; Department of Bioinformatics and Computational Biology, Genentech Inc, South San Francisco, 94080, CA, USA., Hunkapiller J; Department of Human Genetics, Genentech Inc, South San Francisco, 94080, CA, USA., Reeder J; Department of Bioinformatics and Computational Biology, Genentech Inc, South San Francisco, 94080, CA, USA., Mukhyala K; Department of Bioinformatics and Computational Biology, Genentech Inc, South San Francisco, 94080, CA, USA., Cuenco KT; Department of Human Genetics, Genentech Inc, South San Francisco, 94080, CA, USA., Tom JA; Department of Bioinformatics and Computational Biology, Genentech Inc, South San Francisco, 94080, CA, USA., Cowgill A; Department of Bioinformatics and Computational Biology, Genentech Inc, South San Francisco, 94080, CA, USA., Vogel J; Department of Bioinformatics and Computational Biology, Genentech Inc, South San Francisco, 94080, CA, USA., Forrest WF; Department of Bioinformatics and Computational Biology, Genentech Inc, South San Francisco, 94080, CA, USA., Behrens TW; Department of Human Genetics, Genentech Inc, South San Francisco, 94080, CA, USA., Graham RR; Department of Human Genetics, Genentech Inc, South San Francisco, 94080, CA, USA., Wuster A; Department of Human Genetics, Genentech Inc, South San Francisco, 94080, CA, USA. wustera@gene.com.; Department of Bioinformatics and Computational Biology, Genentech Inc, South San Francisco, 94080, CA, USA. wustera@gene.com.

المصدر: Genes and immunity [Genes Immun] 2019 Feb; Vol. 20 (2), pp. 172-179. Date of Electronic Publication: 2018 Mar 18.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: Nature Pub. Group Country of Publication: England NLM ID: 100953417 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5470 (Electronic) Linking ISSN: 14664879 NLM ISO Abbreviation: Genes Immun Subsets: MEDLINE

مواضيع طبية MeSH: Placebo Effect* , Polymorphism, Single Nucleotide*, Clinical Trials, Phase III as Topic/*standards, Adolescent ; Adult ; Aged ; Aged, 80 and over ; Arthritis, Rheumatoid/drug therapy ; Arthritis, Rheumatoid/genetics ; Asthma/drug therapy ; Asthma/genetics ; Female ; Genome-Wide Association Study ; Humans ; Male ; Middle Aged

المؤلفون: Dressen A; Genentech, South San Francisco, CA, USA., Abbas AR; Genentech, South San Francisco, CA, USA., Cabanski C; Genentech, South San Francisco, CA, USA., Reeder J; Genentech, South San Francisco, CA, USA., Ramalingam TR; Genentech, South San Francisco, CA, USA., Neighbors M; Genentech, South San Francisco, CA, USA., Bhangale TR; Genentech, South San Francisco, CA, USA., Brauer MJ; Genentech, South San Francisco, CA, USA., Hunkapiller J; Genentech, South San Francisco, CA, USA., Reeder J; Genentech, South San Francisco, CA, USA., Mukhyala K; Genentech, South San Francisco, CA, USA., Cuenco K; Genentech, South San Francisco, CA, USA., Tom J; Genentech, South San Francisco, CA, USA., Cowgill A; Genentech, South San Francisco, CA, USA., Vogel J; Genentech, South San Francisco, CA, USA., Forrest WF; Genentech, South San Francisco, CA, USA., Collard HR; Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California, San Francisco, CA, USA., Wolters PJ; Division of Pulmonary and Critical Care Medicine, Department of Medicine, University of California, San Francisco, CA, USA., Kropski JA; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Veterans Affairs Medical Center, Nashville, TN, USA., Lancaster LH; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA., Blackwell TS; Division of Allergy, Pulmonary and Critical Care Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA; Cell and Developmental Biology, and Cancer Biology, Department of Medicine, Vanderbilt University Medical Center, Nashville, TN, USA; Department of Veterans Affairs Medical Center, Nashville, TN, USA., Arron JR; Genentech, South San Francisco, CA, USA., Yaspan BL; Genentech, South San Francisco, CA, USA. Electronic address: yaspan.brian@gene.com.

المصدر: The Lancet. Respiratory medicine [Lancet Respir Med] 2018 Aug; Vol. 6 (8), pp. 603-614. Date of Electronic Publication: 2018 Jun 18.

نوع المنشور: Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Elsevier Country of Publication: England NLM ID: 101605555 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2619 (Electronic) Linking ISSN: 22132600 NLM ISO Abbreviation: Lancet Respir Med Subsets: MEDLINE

مواضيع طبية MeSH: Idiopathic Pulmonary Fibrosis/*blood , Mucin-5B/*blood , Telomere Homeostasis/*genetics, Aged ; Case-Control Studies ; Clinical Trials as Topic ; Female ; Humans ; Idiopathic Pulmonary Fibrosis/genetics ; Male ; Middle Aged ; Whole Genome Sequencing

المؤلفون: Chang D; Genentech, Inc., South San Francisco, California, USA., Nalls MA; Laboratory of Neurogenetics, National Institute on Aging, US National Institutes of Health, Bethesda, Maryland, USA.; Data Tecnica International, Glen Echo, Maryland, USA., Hallgrímsdóttir IB; 23andMe Inc., Mountain View, California, USA., Hunkapiller J; Genentech, Inc., South San Francisco, California, USA., van der Brug M; Genentech, Inc., South San Francisco, California, USA., Cai F; Genentech, Inc., South San Francisco, California, USA., Kerchner GA; Genentech, Inc., South San Francisco, California, USA., Ayalon G; Genentech, Inc., South San Francisco, California, USA., Bingol B; Genentech, Inc., South San Francisco, California, USA., Sheng M; Genentech, Inc., South San Francisco, California, USA., Hinds D; 23andMe Inc., Mountain View, California, USA., Behrens TW; Genentech, Inc., South San Francisco, California, USA., Singleton AB; Laboratory of Neurogenetics, National Institute on Aging, US National Institutes of Health, Bethesda, Maryland, USA., Bhangale TR; Genentech, Inc., South San Francisco, California, USA., Graham RR; Genentech, Inc., South San Francisco, California, USA.

مؤلفون مشاركون: International Parkinson's Disease Genomics Consortium, 23andMe Research Team

المصدر: Nature genetics [Nat Genet] 2017 Oct; Vol. 49 (10), pp. 1511-1516. Date of Electronic Publication: 2017 Sep 11.

نوع المنشور: Journal Article; Meta-Analysis

بيانات الدورية: Publisher: Nature Pub. Co Country of Publication: United States NLM ID: 9216904 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1546-1718 (Electronic) Linking ISSN: 10614036 NLM ISO Abbreviation: Nat Genet Subsets: MEDLINE

مواضيع طبية MeSH: Genome-Wide Association Study*, Parkinson Disease/*genetics, Antiparkinson Agents/pharmacology ; Autophagy/genetics ; Case-Control Studies ; Genetic Predisposition to Disease ; Humans ; Linkage Disequilibrium ; Lysosomes/physiology ; Molecular Targeted Therapy ; Parkinson Disease/drug therapy ; Parkinson Disease/epidemiology ; Risk ; Transcription Factors

المؤلفون: Tom JA; Bioinformatics and Computational Biology Department, Genentech Inc, 1 DNA Way, South San Francisco, CA, 94080, USA. tom.jennifer@gene.com., Reeder J; Bioinformatics and Computational Biology Department, Genentech Inc, 1 DNA Way, South San Francisco, CA, 94080, USA., Forrest WF; Bioinformatics and Computational Biology Department, Genentech Inc, 1 DNA Way, South San Francisco, CA, 94080, USA., Graham RR; Human Genetics Department, Genentech Inc, 1 DNA Way, South San Francisco, CA, 94080, USA., Hunkapiller J; Human Genetics Department, Genentech Inc, 1 DNA Way, South San Francisco, CA, 94080, USA., Behrens TW; Human Genetics Department, Genentech Inc, 1 DNA Way, South San Francisco, CA, 94080, USA., Bhangale TR; Bioinformatics and Computational Biology Department, Genentech Inc, 1 DNA Way, South San Francisco, CA, 94080, USA.; Human Genetics Department, Genentech Inc, 1 DNA Way, South San Francisco, CA, 94080, USA.

المصدر: BMC bioinformatics [BMC Bioinformatics] 2017 Jul 24; Vol. 18 (1), pp. 351. Date of Electronic Publication: 2017 Jul 24.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: BioMed Central Country of Publication: England NLM ID: 100965194 Publication Model: Electronic Cited Medium: Internet ISSN: 1471-2105 (Electronic) Linking ISSN: 14712105 NLM ISO Abbreviation: BMC Bioinformatics Subsets: MEDLINE

مواضيع طبية MeSH: Genome-Wide Association Study/*methods, Genotype ; High-Throughput Nucleotide Sequencing ; Humans ; Macular Degeneration/genetics ; Macular Degeneration/pathology ; Phenotype ; Polymorphism, Single Nucleotide ; Principal Component Analysis ; Sequence Analysis, DNA ; Software

المؤلفون: Randolph AG; Department of Anesthesia, Perioperative and Pain Medicine, Boston Children's Hospital.; Departments of Anaesthesia and Pediatrics, Harvard Medical School, Boston., Yip WK; Foundation Medicine Inc, Cambridge, Massachusetts., Allen EK; Department of Immunology, St Jude Children's Research Hospital, Memphis, Tennessee., Rosenberger CM; Biomarker Discovery, Genentech, Inc, South San Francisco, California., Agan AA; Department of Anesthesia, Perioperative and Pain Medicine, Boston Children's Hospital., Ash SA; Department of Anesthesia, Perioperative and Pain Medicine, Boston Children's Hospital., Zhang Y; Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland., Bhangale TR; Human Genetics, Genentech, Inc, South San Francisco, California., Finkelstein D; Department of Computational Biology, St Jude Children's Research Hospital, Memphis, Tennessee., Cvijanovich NZ; Pediatric Critical Care, UCSF Benioff Children's Hospital Oakland, California., Mourani PM; Section of Critical Care, Department of Pediatrics, University of Colorado School of Medicine and Research Institute, Children's Hospital Colorado, Aurora., Hall MW; Critical Care Medicine, Nationwide Children's Hospital, Columbus, Ohio., Su HC; Laboratory of Host Defenses, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, Maryland., Thomas PG; Department of Immunology, St Jude Children's Research Hospital, Memphis, Tennessee.

مؤلفون مشاركون: Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network Pediatric Influenza (PICFLU) Investigators, Pediatric Acute Lung Injury and Sepsis Investigators (PALISI) Network Pediatric Influenza (PICFLU) Investigators

المصدر: The Journal of infectious diseases [J Infect Dis] 2017 Jul 01; Vol. 216 (1), pp. 14-21.

نوع المنشور: Journal Article; Multicenter Study; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: Oxford University Press Country of Publication: United States NLM ID: 0413675 Publication Model: Print Cited Medium: Internet ISSN: 1537-6613 (Electronic) Linking ISSN: 00221899 NLM ISO Abbreviation: J Infect Dis Subsets: MEDLINE

مواضيع طبية MeSH: Influenza, Human/*genetics , Membrane Proteins/*genetics , RNA-Binding Proteins/*genetics, Black or African American/genetics ; Child ; Child, Preschool ; Female ; Genetic Predisposition to Disease ; Genotyping Techniques ; Homozygote ; Humans ; Influenza A virus ; Male ; Polymorphism, Single Nucleotide ; Prospective Studies ; Protein Isoforms/genetics ; RNA, Viral/isolation & purification

المؤلفون: Yaspan BL; Genentech Inc., South San Francisco, CA 94080, USA., Williams DF; VitreoRetinal Surgery, PA, Minneapolis, MN 55404, USA., Holz FG; Department of Ophthalmology, University of Bonn, Bonn, Germany., Regillo CD; Wills Eye Hospital, Philadelphia, PA 19107, USA., Li Z; Genentech Inc., South San Francisco, CA 94080, USA., Dressen A; Genentech Inc., South San Francisco, CA 94080, USA., van Lookeren Campagne M; Genentech Inc., South San Francisco, CA 94080, USA., Le KN; Genentech Inc., South San Francisco, CA 94080, USA., Graham RR; Genentech Inc., South San Francisco, CA 94080, USA., Beres T; Genentech Inc., South San Francisco, CA 94080, USA., Bhangale TR; Genentech Inc., South San Francisco, CA 94080, USA., Honigberg LA; Genentech Inc., South San Francisco, CA 94080, USA., Smith A; Genentech Inc., South San Francisco, CA 94080, USA., Henry EC; Genentech Inc., South San Francisco, CA 94080, USA., Ho C; Genentech Inc., South San Francisco, CA 94080, USA., Strauss EC; Genentech Inc., South San Francisco, CA 94080, USA. strauss.erich@gene.com.

مؤلفون مشاركون: MAHALO Study Investigators

المصدر: Science translational medicine [Sci Transl Med] 2017 Jun 21; Vol. 9 (395).

نوع المنشور: Clinical Trial, Phase II; Journal Article; Multicenter Study; Randomized Controlled Trial

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101505086 Publication Model: Print Cited Medium: Internet ISSN: 1946-6242 (Electronic) Linking ISSN: 19466234 NLM ISO Abbreviation: Sci Transl Med Subsets: MEDLINE

مواضيع طبية MeSH: Geographic Atrophy/*drug therapy , Geographic Atrophy/*metabolism , Immunoglobulin Fab Fragments/*therapeutic use , Macular Degeneration/*drug therapy , Macular Degeneration/*metabolism, Aged ; Complement Factor D/antagonists & inhibitors ; Complement Factor D/metabolism ; Complement Pathway, Alternative ; Disease Progression ; Female ; Geographic Atrophy/pathology ; Humans ; Macular Degeneration/pathology ; Male ; Middle Aged