نتائج البحث - "Bhavanam Sekhara Reddy"

1

Synthesis and characterization of potential impurities of ezetimibe

المؤلفون: Deekonda Satheesh, Dharmasoth Rama Devi, Keloth Basavaiah, B. Sreenivasulu, Bhavanam Sekhara Reddy, Balakrishna Aegurla, Pallerla Satish Kumar, Anil Kumar Guduri, Ramadas Chavakula

المصدر: Journal of Heterocyclic Chemistry. 60:318-326

مصطلحات موضوعية: Organic Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::3784fcfd8853740631efb8552c96fa15
https://doi.org/10.1002/jhet.4584

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2

Synthesis and characterization of impurities of Apixaban drug substance—An anticoagulant

المؤلفون: Deekonda Satheesh, B. Sreenivasulu, Bhavanam Sekhara Reddy, U. Rajasekhar Reddy, J. S. Chakradhar Saladi, P. Badrinath Gupta, Aaramadaka Sunil Kumar Reddy, Balakrishna Aegurla, Keloth Basavaiah

المصدر: Journal of Heterocyclic Chemistry. 59:1736-1741

مصطلحات موضوعية: Organic Chemistry

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c92e15897b0c9320a2707b505b2e47c5
https://doi.org/10.1002/jhet.4501

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3

Highly Selective and Potent Human β-Secretase 2 (BACE2) Inhibitors against Type 2 Diabetes: Design, Synthesis, X-ray Structure and Structure-Activity Relationship Studies

المؤلفون: Emma K. Lendy, Bhavanam Sekhara Reddy, Satish Kovela, Emilio L. Cárdenas, Andrew D. Mesecar, Yu-Chen Yen, Margherita Brindisi, Xiangping Huang, Jordan Tang, Arun K. Ghosh, Deborah Downs, Kalapala Venketeswara Rao

المساهمون: Ghosh, A. K., Brindisi, M., Yen, Y. -C., Lendy, E. K., Kovela, S., Cardenas, E. L., Reddy, B. S., Rao, K. V., Downs, D., Huang, X., Tang, J., Mesecar, A. D.

المصدر: ChemMedChem. 14(5)

مصطلحات موضوعية: Isostere, Stereochemistry, BACE2 inhibitor, Drug Evaluation, Preclinical, Crystallography, X-Ray, Biochemistry, Article, chemistry.chemical_compound, Structure-Activity Relationship, Tmem27, Drug Discovery, Amyloid precursor protein, Ethylamines, Structure–activity relationship, Aspartic Acid Endopeptidases, Humans, Hypoglycemic Agents, General Pharmacology, Toxicology and Pharmaceutics, Enzyme Inhibitors, Pharmacology, chemistry.chemical_classification, type 2 diabete, Trifluoromethyl, Binding Sites, biology, Molecular Structure, Organic Chemistry, BACE2 inhibitors, structure-based design, type 2 diabetes, β-secretase 2, Molecular Docking Simulation, Memapsin 1, Enzyme, chemistry, Diabetes Mellitus, Type 2, Docking (molecular), biology.protein, Molecular Medicine, Thermodynamics, Amyloid Precursor Protein Secretases, Selectivity, Protein Binding

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9fba27ca172570d648b5c71e66b4c56d
https://pubmed.ncbi.nlm.nih.gov/30637955

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4

Design of potent and highly selective inhibitors for human β-secretase 2 (memapsin 1), a target for type 2 diabetes

المؤلفون: Andrew D. Mesecar, Emilio L. Cárdenas, Deborah Downs, Kanury V. S. Rao, Yu-Chen Yen, Xiangping Huang, Jordan Tang, Arun K. Ghosh, Bhavanam Sekhara Reddy

المصدر: Chemical Science. 7:3117-3122

مصطلحات موضوعية: 0301 basic medicine, Cathepsin, Chemistry, General Chemistry, Type 2 diabetes, Pharmacology, Highly selective, medicine.disease, Combinatorial chemistry, 3. Good health, 03 medical and health sciences, Memapsin 1, 030104 developmental biology, β secretase, medicine

URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::573b8d66f02273c2c3c567ed0e16a2b0
https://doi.org/10.1039/c5sc03718b

5

Design of Highly Potent, Dual-Acting and Central-Nervous-System-Penetrating HIV-1 Protease Inhibitors with Excellent Potency against Multidrug-Resistant HIV-1 Variants

المؤلفون: Kanury V. S. Rao, Johnson Agniswamy, Arun K. Ghosh, Hiroaki Mitsuya, Heather L. Osswald, Yuan-Fang Wang, Irene T. Weber, Prasanth R. Nyalapatla, Margherita Brindisi, Satish Kovela, Shinichiro Hattori, Bhavanam Sekhara Reddy, Manabu Aoki

المساهمون: Ghosh, Arun K, Rao, Kalapala Venkateswara, Nyalapatla, Prasanth R, Kovela, Satish, Brindisi, Margherita, Osswald, Heather L, Sekhara Reddy, Bhavanam, Agniswamy, Johnson, Wang, Yuan-Fang, Aoki, Manabu, Hattori, Shin-Ichiro, Weber, Irene T, Mitsuya, Hiroaki

مصطلحات موضوعية: 0301 basic medicine, Models, Molecular, Carbamate, Halogenation, medicine.medical_treatment, HIV Infections, Crystallography, X-Ray, 01 natural sciences, Biochemistry, Article, brain penetration, Cell Line, antiviral agent, 03 medical and health sciences, chemistry.chemical_compound, HIV-1 protease, HIV Protease, Drug Discovery, antiviral agents, medicine, Potency, HIV Protease Inhibitor, Animals, Humans, General Pharmacology, Toxicology and Pharmaceutics, Thiazole, Pharmacology, Protease, drug resistance, biology, 010405 organic chemistry, Organic Chemistry, Brain, HIV Protease Inhibitors, structure-based design, 0104 chemical sciences, Rats, Multiple drug resistance, 030104 developmental biology, chemistry, Cell culture, Drug Design, biology.protein, HIV-1, Molecular Medicine, Carbamates