المؤلفون: Bhola PD; Dana Farber Cancer Institute, Boston, Massachusetts., Letai A; Dana Farber Cancer Institute, Boston, Massachusetts.

المصدر: Blood cancer discovery [Blood Cancer Discov] 2024 Mar 01; Vol. 5 (2), pp. 81-82.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101764786 Publication Model: Print Cited Medium: Internet ISSN: 2643-3249 (Electronic) Linking ISSN: 26433230 NLM ISO Abbreviation: Blood Cancer Discov Subsets: MEDLINE

مواضيع طبية MeSH: Military Personnel* , Sports*, Humans ; Animals ; Confusion ; Mythology ; Urodela

المؤلفون: Lecky E; Dana Farber Cancer Institute, Boston MA 02215, USA., Mukherji A; Dana Farber Cancer Institute, Boston MA 02215, USA., German R; Dana Farber Cancer Institute, Boston MA 02215, USA., Antonellis G; Dana Farber Cancer Institute, Boston MA 02215, USA., Lin JR; Harvard Medical School, Boston MA 02215, USA., Yorsz M; Dana Farber Cancer Institute, Boston MA 02215, USA., McQueeney KE; Dana Farber Cancer Institute, Boston MA 02215, USA., Ryan J; Dana Farber Cancer Institute, Boston MA 02215, USA., Ng K; Dana Farber Cancer Institute, Boston MA 02215, USA., Sicinska E; Dana Farber Cancer Institute, Boston MA 02215, USA., Sorger PK; Harvard Medical School, Boston MA 02215, USA., Letai A; Dana Farber Cancer Institute, Boston MA 02215, USA.; Harvard Medical School, Boston MA 02215, USA., Bhola PD; Dana Farber Cancer Institute, Boston MA 02215, USA.; Harvard Medical School, Boston MA 02215, USA.

المصدر: Science advances [Sci Adv] 2023 Jun 23; Vol. 9 (25), pp. eadg4128. Date of Electronic Publication: 2023 Jun 23.

نوع المنشور: Journal Article

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE

مواضيع طبية MeSH: Neoplasms*/metabolism , Neoplasms*/pathology , Apoptosis*, Proteomics ; Humans ; Single-Cell Analysis ; Cell Line, Tumor

المؤلفون: Lalazar G; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.; Division of Gastroenterology and Hepatology, Weill Cornell Medicine, New York, New York., Requena D; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York., Ramos-Espiritu L; High Throughput and Spectroscopy Resource Center, The Rockefeller University, New York, New York., Ng D; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York., Bhola PD; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., de Jong YP; Division of Gastroenterology and Hepatology, Weill Cornell Medicine, New York, New York.; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York., Wang R; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York., Narayan NJC; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.; Pediatric Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York., Shebl B; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York., Levin S; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York., Michailidis E; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York., Kabbani M; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York., Vercauteren KOA; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York.; Laboratory of Liver Infectious Diseases, Ghent University, Ghent, Belgium.; Institute of Tropical Medicine, Antwerp, Belgium., Hurley AM; Hospital Program Direction, The Rockefeller University, New York, New York., Farber BA; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.; Department of Surgery, Division of Pediatric Surgery, University of Iowa Hospitals and Clinics, Iowa City, Iowa., Hammond WJ; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.; Pediatric Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Surgery, New York Presbyterian Hospital-Weill Cornell Medical Center, New York, New York., Saltsman JA 3rd; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York.; Pediatric Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York.; Department of Surgery, Mount Sinai Hospital, New York, New York., Weinberg EM; Division of Gastroenterology and Hepatology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania., Glickman JF; High Throughput and Spectroscopy Resource Center, The Rockefeller University, New York, New York., Lyons BA; Department of Chemistry and Biochemistry, New Mexico State University, Las Cruces, New Mexico., Ellison J; Division of Transplantation, Rush University Medical Center, Chicago, Illinois., Schadde E; Department of Surgery, Division of Transplantation and Division of Surgical Oncology, Rush University Medical Center, Chicago, Illinois., Hertl M; Division of Transplantation, Rush University Medical Center, Chicago, Illinois., Leiting JL; Division of Subspecialty General Surgery, Department of Surgery, Mayo Clinic, Rochester, Minnesota., Truty MJ; Division of Subspecialty General Surgery, Department of Surgery, Mayo Clinic, Rochester, Minnesota., Smoot RL; Division of Subspecialty General Surgery, Department of Surgery, Mayo Clinic, Rochester, Minnesota., Tierney F; Division of Abdominal Organ Transplantation, New York-Presbyterian/Columbia University, New York, New York., Kato T; Division of Abdominal Organ Transplantation, New York-Presbyterian/Columbia University, New York, New York., Wendel HG; Cancer Biology and Genetics Program, Memorial Sloan Kettering Cancer Center, New York, New York., LaQuaglia MP; Pediatric Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, New York., Rice CM; Laboratory of Virology and Infectious Disease, The Rockefeller University, New York, New York., Letai A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Coffino P; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York., Torbenson MS; Division of Anatomic Pathology, Mayo Clinic, Rochester, Minnesota., Ortiz MV; Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, New York., Simon SM; Laboratory of Cellular Biophysics, The Rockefeller University, New York, New York. simon@rockefeller.edu.

المصدر: Cancer discovery [Cancer Discov] 2021 Oct; Vol. 11 (10), pp. 2544-2563. Date of Electronic Publication: 2021 Jun 14.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101561693 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2159-8290 (Electronic) Linking ISSN: 21598274 NLM ISO Abbreviation: Cancer Discov Subsets: MEDLINE

مواضيع طبية MeSH: Gene Expression Regulation, Neoplastic* , Xenograft Model Antitumor Assays*, Carcinoma, Hepatocellular/*drug therapy , Liver Neoplasms/*drug therapy, Aniline Compounds/therapeutic use ; Animals ; Antineoplastic Agents/therapeutic use ; Benzofurans/therapeutic use ; Carcinoma, Hepatocellular/genetics ; Female ; Humans ; Liver Neoplasms/genetics ; Male ; Mice ; Naphthoquinones/therapeutic use ; Sulfonamides/therapeutic use

SCR Disease Name: Fibrolamellar hepatocellular carcinoma

المؤلفون: Daniels VW; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.; Ludwig Center at Harvard, Boston, MA 02215, USA., Zoeller JJ; Ludwig Center at Harvard, Boston, MA 02215, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA 02215, USA., van Gastel N; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA.; Harvard Stem Cell Institute, Harvard University, Cambridge, MA 02138, USA.; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA 02114, USA., McQueeney KE; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Parvin S; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Potter DS; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Fell GG; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Ferreira VG; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA.; Instituto de Química de São Carlos, Universidade de São Paulo, São Carlos, SP 13568-250, Brazil.; Instituto Nacional de Ciência e Tecnologia de Bioanalítica, INCTBio, Campinas, SP 13083-970, Brazil., Yilma B; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Gupta R; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Spetz J; Department of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, MA 02215, USA., Bhola PD; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Endress JE; Ludwig Center at Harvard, Boston, MA 02215, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA 02215, USA., Harris IS; Ludwig Center at Harvard, Boston, MA 02215, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA 02215, USA.; Department of Biomedical Genetics and Wilmot Cancer Institute, University of Rochester Medical Center, 601 Elmwood Ave., Rochester, NY 14642, USA., Carrilho E; Instituto de Química de São Carlos, Universidade de São Paulo, São Carlos, SP 13568-250, Brazil.; Instituto Nacional de Ciência e Tecnologia de Bioanalítica, INCTBio, Campinas, SP 13083-970, Brazil., Sarosiek KA; Department of Environmental Health, Harvard T. H. Chan School of Public Health, Boston, MA 02215, USA., Scadden DT; Department of Stem Cell and Regenerative Biology, Harvard University, Cambridge, MA 02138, USA.; Harvard Stem Cell Institute, Harvard University, Cambridge, MA 02138, USA.; Center for Regenerative Medicine, Massachusetts General Hospital, Boston, MA 02114, USA., Brugge JS; Ludwig Center at Harvard, Boston, MA 02215, USA.; Department of Cell Biology, Harvard Medical School, Boston, MA 02215, USA., Letai A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA. anthony_letai@dfci.harvard.edu.; Ludwig Center at Harvard, Boston, MA 02215, USA.

المصدر: Science signaling [Sci Signal] 2021 Jun 08; Vol. 14 (686). Date of Electronic Publication: 2021 Jun 08.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE

مواضيع طبية MeSH: Triple Negative Breast Neoplasms*/drug therapy, Apoptosis ; Apoptosis Regulatory Proteins ; Cell Line, Tumor ; Humans ; Mitochondria ; Myeloid Cell Leukemia Sequence 1 Protein ; Proto-Oncogene Proteins c-bcl-2

المؤلفون: Bhola PD; Dana-Farber Cancer Institute, Boston, MA 02215, USA.; Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA 02115, USA., Ahmed E; Dana-Farber Cancer Institute, Boston, MA 02215, USA., Guerriero JL; Dana-Farber Cancer Institute, Boston, MA 02215, USA., Sicinska E; Dana-Farber Cancer Institute, Boston, MA 02215, USA., Su E; Dana-Farber Cancer Institute, Boston, MA 02215, USA., Lavrova E; Dana-Farber Cancer Institute, Boston, MA 02215, USA., Ni J; Dana-Farber Cancer Institute, Boston, MA 02215, USA., Chipashvili O; Dana-Farber Cancer Institute, Boston, MA 02215, USA., Hagan T; Dana-Farber Cancer Institute, Boston, MA 02215, USA., Pioso MS; Dana-Farber Cancer Institute, Boston, MA 02215, USA., McQueeney K; Dana-Farber Cancer Institute, Boston, MA 02215, USA., Ng K; Dana-Farber Cancer Institute, Boston, MA 02215, USA., Aguirre AJ; Dana-Farber Cancer Institute, Boston, MA 02215, USA.; Broad Institute, Cambridge, MA 02115, USA., Cleary JM; Dana-Farber Cancer Institute, Boston, MA 02215, USA., Cocozziello D; Broad Institute, Cambridge, MA 02115, USA., Sotayo A; Dana-Farber Cancer Institute, Boston, MA 02215, USA., Ryan J; Dana-Farber Cancer Institute, Boston, MA 02215, USA., Zhao JJ; Dana-Farber Cancer Institute, Boston, MA 02215, USA.; Broad Institute, Cambridge, MA 02115, USA.; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02215, USA., Letai A; Dana-Farber Cancer Institute, Boston, MA 02215, USA. anthony_letai@dfci.harvard.edu.; Laboratory of Systems Pharmacology, Harvard Medical School, Boston, MA 02115, USA.; Broad Institute, Cambridge, MA 02115, USA.

المصدر: Science signaling [Sci Signal] 2020 Jun 16; Vol. 13 (636). Date of Electronic Publication: 2020 Jun 16.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101465400 Publication Model: Electronic Cited Medium: Internet ISSN: 1937-9145 (Electronic) Linking ISSN: 19450877 NLM ISO Abbreviation: Sci Signal Subsets: MEDLINE

مواضيع طبية MeSH: Apoptosis/*drug effects , Colonic Neoplasms/*drug therapy , Colonic Neoplasms/*metabolism , Neoplasms, Experimental/*drug therapy , Neoplasms, Experimental/*metabolism, Animals ; Apoptosis/genetics ; Cell Line, Tumor ; Colonic Neoplasms/genetics ; Female ; Humans ; Mice ; Neoplasms, Experimental/genetics ; Xenograft Model Antitumor Assays

المؤلفون: Stover EH; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts.; Cancer Program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Baco MB; Cancer Program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Cohen O; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts.; Cancer Program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Li YY; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts.; Cancer Program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Christie EL; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Victoria, Australia., Bagul M; Cancer Program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Goodale A; Genetic Perturbation Platform, Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Lee Y; Genetic Perturbation Platform, Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Pantel S; Genetic Perturbation Platform, Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Rees MG; Cancer Program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Wei G; Cancer Program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Presser AG; John B. Little Center for Radiation Sciences, Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts., Gelbard MK; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Zhang W; Cancer Program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Zervantonakis IK; Department of Cell Biology, Harvard Medical School, Boston, Massachusetts., Bhola PD; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Ryan J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Guerriero JL; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts., Montero J; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Institute for Bioengineering of Catalonia, Barcelona, Spain., Liang FJ; Cancer Program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Cherniack AD; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Cancer Program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Piccioni F; Genetic Perturbation Platform, Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Matulonis UA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts., Bowtell DDL; Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia.; Sir Peter MacCallum Department of Oncology, The University of Melbourne, Victoria, Australia., Sarosiek KA; John B. Little Center for Radiation Sciences, Department of Environmental Health, Harvard T.H. Chan School of Public Health, Boston, Massachusetts., Letai A; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts.; Department of Medicine, Harvard Medical School, Boston, Massachusetts., Garraway LA; Eli Lilly and Company, Indianapolis, Indiana., Johannessen CM; Cancer Program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts., Meyerson M; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, Massachusetts. matthew_meyerson@dfci.harvard.edu.; Department of Medicine, Harvard Medical School, Boston, Massachusetts.; Cancer Program, Broad Institute of Harvard and MIT, Cambridge, Massachusetts.

المصدر: Molecular cancer research : MCR [Mol Cancer Res] 2019 Nov; Vol. 17 (11), pp. 2281-2293. Date of Electronic Publication: 2019 Aug 28.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't

بيانات الدورية: Publisher: American Association for Cancer Research Country of Publication: United States NLM ID: 101150042 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1557-3125 (Electronic) Linking ISSN: 15417786 NLM ISO Abbreviation: Mol Cancer Res Subsets: MEDLINE

مواضيع طبية MeSH: Drug Resistance, Neoplasm*, Antineoplastic Agents/*pharmacology , Apoptosis/*genetics , Apoptosis Regulatory Proteins/*genetics , Myeloid Cell Leukemia Sequence 1 Protein/*antagonists & inhibitors , Ovarian Neoplasms/*genetics , bcl-X Protein/*antagonists & inhibitors, Cell Line, Tumor ; Cisplatin/pharmacology ; Female ; Genomics ; Humans ; Myeloid Cell Leukemia Sequence 1 Protein/genetics ; Myeloid Cell Leukemia Sequence 1 Protein/metabolism ; Ovarian Neoplasms/drug therapy ; Paclitaxel/pharmacology ; bcl-X Protein/genetics ; bcl-X Protein/metabolism

المؤلفون: Sarosiek KA; Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Mayer 430, Boston, MA 02115, USA; Harvard Medical School, Boston, MA 02115, USA., Fraser C; Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Mayer 430, Boston, MA 02115, USA., Muthalagu N; Cancer Research UK Beatson Institute, Glasgow G61 1BD, Scotland., Bhola PD; Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Mayer 430, Boston, MA 02115, USA; Harvard Medical School, Boston, MA 02115, USA., Chang W; Harvard Medical School, Boston, MA 02115, USA; Division of Genetics and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., McBrayer SK; Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Mayer 430, Boston, MA 02115, USA; Harvard Medical School, Boston, MA 02115, USA., Cantlon A; Harvard Medical School, Boston, MA 02115, USA; Division of Genetics and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Fisch S; Harvard Medical School, Boston, MA 02115, USA; Division of Genetics and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Golomb-Mello G; Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI 02912, USA., Ryan JA; Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Mayer 430, Boston, MA 02115, USA; Harvard Medical School, Boston, MA 02115, USA., Deng J; Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Mayer 430, Boston, MA 02115, USA; Harvard Medical School, Boston, MA 02115, USA., Jian B; Department of Neurosurgery, Kaiser Permanente, Sacramento, CA 95815, USA., Corbett C; Department of Neurosurgery, Boston Children's Hospital, Boston, MA 02115, USA., Goldenberg M; Department of Neurosurgery, Boston Children's Hospital, Boston, MA 02115, USA., Madsen JR; Harvard Medical School, Boston, MA 02115, USA; Department of Neurosurgery, Boston Children's Hospital, Boston, MA 02115, USA., Liao R; Harvard Medical School, Boston, MA 02115, USA; Division of Genetics and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Walsh D; Harvard Medical School, Boston, MA 02115, USA; Division of Genetics and Division of Cardiovascular Medicine, Department of Medicine, Brigham and Women's Hospital, Boston, MA 02115, USA., Sedivy J; Department of Molecular Biology, Cell Biology and Biochemistry, Brown University, Providence, RI 02912, USA., Murphy DJ; Cancer Research UK Beatson Institute, Glasgow G61 1BD, Scotland; Institute of Cancer Sciences, University of Glasgow, Glasgow G61 1BD, Scotland., Carrasco DR; Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Mayer 430, Boston, MA 02115, USA; Harvard Medical School, Boston, MA 02115, USA., Robinson S; Harvard Medical School, Boston, MA 02115, USA; Department of Neurosurgery, Boston Children's Hospital, Boston, MA 02115, USA., Moslehi J; Division of Cardiovascular Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA; Division of Hematology-Oncology, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA; Cardio-Oncology Program, Department of Medicine, Vanderbilt-Ingram Cancer Center, Vanderbilt University School of Medicine, Nashville, TN 37232, USA., Letai A; Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Mayer 430, Boston, MA 02115, USA; Harvard Medical School, Boston, MA 02115, USA. Electronic address: anthony_letai@dfci.harvard.edu.

المصدر: Cancer cell [Cancer Cell] 2017 Jan 09; Vol. 31 (1), pp. 142-156. Date of Electronic Publication: 2016 Dec 22.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 101130617 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-3686 (Electronic) Linking ISSN: 15356108 NLM ISO Abbreviation: Cancer Cell Subsets: MEDLINE

مواضيع طبية MeSH: Apoptosis*, Mitochondria/*physiology , Neoplasms/*drug therapy , Proto-Oncogene Proteins c-myc/*physiology, Age Factors ; Animals ; Doxorubicin/toxicity ; Humans ; Mice ; Neoplasms/pathology ; Organ Specificity ; bcl-2 Homologous Antagonist-Killer Protein/physiology ; bcl-2-Associated X Protein/physiology

المؤلفون: Bhola PD, Mar BG, Lindsley RC, Ryan JA, Hogdal LJ, Vo TT, DeAngelo DJ, Galinsky I, Ebert BL, Letai A

المصدر: The Journal of clinical investigation [J Clin Invest] 2016 Oct 03; Vol. 126 (10), pp. 3827-3836. Date of Electronic Publication: 2016 Sep 06.

نوع المنشور: Journal Article; Research Support, Non-U.S. Gov't; Research Support, N.I.H., Extramural

بيانات الدورية: Publisher: American Society for Clinical Investigation Country of Publication: United States NLM ID: 7802877 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1558-8238 (Electronic) Linking ISSN: 00219738 NLM ISO Abbreviation: J Clin Invest Subsets: MEDLINE

مواضيع طبية MeSH: Apoptosis/*drug effects , Leukemia, Myeloid, Acute/*pathology, Antineoplastic Agents, Phytogenic/pharmacology ; Cell Line, Tumor ; Cell Survival/drug effects ; Drug Resistance, Neoplasm ; Drug Screening Assays, Antitumor ; Etoposide/pharmacology ; Granulocyte Precursor Cells/drug effects ; Granulocyte Precursor Cells/physiology ; Humans ; Inhibitory Concentration 50 ; Leukemia, Myeloid, Acute/drug therapy ; Mitochondria/drug effects ; Single-Cell Analysis

المؤلفون: Bhola PD; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA., Letai A; Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA; Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA 02215, USA. Electronic address: anthony_letai@dfci.harvard.edu.

المصدر: Molecular cell [Mol Cell] 2016 Mar 03; Vol. 61 (5), pp. 695-704.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Review

بيانات الدورية: Publisher: Cell Press Country of Publication: United States NLM ID: 9802571 Publication Model: Print Cited Medium: Internet ISSN: 1097-4164 (Electronic) Linking ISSN: 10972765 NLM ISO Abbreviation: Mol Cell Subsets: MEDLINE

مواضيع طبية MeSH: Apoptosis*/drug effects , Signal Transduction*/drug effects, Apoptosis Regulatory Proteins/*metabolism , Mitochondria/*metabolism , Mitochondria/*pathology, Animals ; Antineoplastic Agents/therapeutic use ; Humans ; Mitochondria/drug effects ; Mitochondrial Membrane Transport Proteins/metabolism ; Mitochondrial Membranes/metabolism ; Mitochondrial Permeability Transition Pore ; Molecular Targeted Therapy ; Neoplasms/drug therapy ; Neoplasms/metabolism ; Neoplasms/pathology ; Permeability ; Protein Binding ; Protein Interaction Domains and Motifs ; Proto-Oncogene Proteins c-bcl-2/metabolism

المؤلفون: Bhola PD; Department of Cellular Biophysics, The Rockefeller University, New York, NY 10065, USA., Simon SM

المصدر: Journal of cell science [J Cell Sci] 2009 Dec 01; Vol. 122 (Pt 23), pp. 4296-302. Date of Electronic Publication: 2009 Nov 03.

نوع المنشور: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, Non-P.H.S.

بيانات الدورية: Publisher: Company of Biologists Country of Publication: England NLM ID: 0052457 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1477-9137 (Electronic) Linking ISSN: 00219533 NLM ISO Abbreviation: J Cell Sci Subsets: MEDLINE

مواضيع طبية MeSH: Apoptosis/*physiology , Cells/*cytology, Animals ; Apoptosis/genetics ; Caspases/metabolism ; Cell Line ; Cells/metabolism ; Epigenesis, Genetic/genetics ; Epigenesis, Genetic/physiology ; HeLa Cells ; Humans ; Mice ; Microscopy, Fluorescence ; NIH 3T3 Cells ; Signal Transduction/genetics ; Signal Transduction/physiology