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1
المؤلفون: Christopher L. Carpenter, Eldridge N. Nartey, Dominic Suarez, Elisabeth A. Minthorn, Jesus R. Medina, Louis V. LaFrance, Ralph A. Rivero, James F. Mack, Charles F. McHugh, Xinrong Tian, Dirk A. Heerding, Christina Ng Di Marco, Thomas J. Berrodin, Aishwarya Bhaskar, Biju Mangatt, William Hoi Hong Li, Brackley James, Martyr Cuthbert, Lorena A. Kallal, Michael Butticello, Jacob Rubin
المصدر: Journal of Medicinal Chemistry. 64:16056-16087
مصطلحات موضوعية: Gene knockdown, Oncogene, Drug discovery, Chemistry, Drug Discovery, Molecular Medicine, Structure–activity relationship, Computational biology, Small molecule binding, Pharmacophore, Small molecule, Function (biology)
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2
المؤلفون: Xinrong Tian, Dominic Suarez, Douglas Thomson, William Li, Elizabeth A. King, Louis LaFrance, Jeffrey Boehm, Linda Barton, Christina Di Marco, Cuthbert Martyr, Reema Thalji, Jesus Medina, Steven Knight, Dirk Heerding, Enoch Gao, Eldridge Nartey, Ted Cecconie, Christopher Nixon, Guofeng Zhang, Thomas J. Berrodin, Christopher Phelps, Amish Patel, Xiaopeng Bai, Ken Lind, Ninad Prabhu, Jeffrey Messer, Zhengrong Zhu, Lisa Shewchuk, Rob Reid, Alan P. Graves, Charles McHugh, Biju Mangatt
المصدر: Journal of medicinal chemistry. 65(21)
مصطلحات موضوعية: Technology, Proline, Drug Discovery, Molecular Medicine, p300-CBP Transcription Factors, Adenovirus E1A Proteins, DNA, CREB-Binding Protein, High-Throughput Screening Assays, Histone Acetyltransferases
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3
المؤلفون: Kimberline Y. Gerrick, Jenny Laraio, Kelsey Annen, Hoang Tran, Marcus M. Fischer, Yevgeniy Freyman, Geeta Sharma, Isaac Bishof, Stephen Federowicz, Divya Pankajakshan, Claire L. Neilan, Biju Mangatt, Anthony Mazurek, Mark R. Lackner, Michael White, Zineb Mounir
المصدر: Cancer Research. 83:1637-1637
مصطلحات موضوعية: Cancer Research, Oncology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::52dcfbf3c9347d14e437737ba3007882
https://doi.org/10.1158/1538-7445.am2023-1637 -
4
المؤلفون: Jesús R, Medina, Xinrong, Tian, William H, Li, Dominic, Suarez, James F, Mack, Louis, LaFrance, Cuthbert, Martyr, James, Brackley, Christina, Di Marco, Ralph, Rivero, Dirk A, Heerding, Charles, McHugh, Elisabeth, Minthorn, Aishwarya, Bhaskar, Jacob, Rubin, Michael, Butticello, Christopher, Carpenter, Eldridge N, Nartey, Thomas J, Berrodin, Lorena A, Kallal, Biju, Mangatt
المصدر: Journal of medicinal chemistry. 64(21)
مصطلحات موضوعية: Proto-Oncogene Proteins c-myc, Small Molecule Libraries, Structure-Activity Relationship, Area Under Curve, Cell Line, Tumor, Drug Discovery, Animals, Humans, Xenograft Model Antitumor Assays, Half-Life, Rats
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5
المؤلفون: Paul Scott-Stevens, Qin Donghui, Allen Oliff, Andrew N. Hobbs, Yoshiaki Washio, Josh Cottom, Jennifer A. Borthwick, Julia Coggins, Robert J. Young, Biju Mangatt, Jordi Munoz-Muriedas, Paris Ward, Siegfried B. Christensen, Helen L. Evans, Jingsong Yang, Nino Campobasso, Graham L. Simpson, Julien Chabanet, Xuan Hong, Sophie M. Bertrand, Susan Chen, Helen C. Dawson
المصدر: Journal of Medicinal Chemistry. 62:2154-2171
مصطلحات موضوعية: 01 natural sciences, Mice, Structure-Activity Relationship, 03 medical and health sciences, hemic and lymphatic diseases, Drug Discovery, Animals, Humans, Proto-Oncogene Proteins c-abl, Protein Kinase Inhibitors, neoplasms, 030304 developmental biology, Myristoylation, 0303 health sciences, Binding Sites, ABL, Molecular Structure, Hematopoietic stem cell differentiation, Chemistry, Kinase, Drug discovery, Small molecule, High-Throughput Screening Assays, 0104 chemical sciences, Cell biology, Thiazoles, 010404 medicinal & biomolecular chemistry, Pyrazoles, Molecular Medicine, Tyrosine kinase, Intracellular, Protein Binding
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6High-Throughput Screening and Triage Assays Identify Small Molecules Targeting c-MYC in Cancer Cells
المؤلفون: Jon-Paul Jaworski, Lisa A. Payne, Anna Waszkiewicz, Biju Mangatt, Anthony J. Jurewicz, Lorena A. Kallal, Jesus R. Medina, Pat Brady, Xin Zeng, Thomas J. Berrodin, Carolyn Doepner-Buser, Anthony Della Pietra
المصدر: SLAS discovery : advancing life sciences RD. 26(2)
مصطلحات موضوعية: 0301 basic medicine, High-throughput screening, Genes, myc, Biochemistry, Analytical Chemistry, Flow cytometry, Small Molecule Libraries, 03 medical and health sciences, 0302 clinical medicine, Drug Discovery, medicine, Fluorescence Resonance Energy Transfer, Humans, Transcription factor, Reporter gene, medicine.diagnostic_test, Cell growth, Chemistry, Reverse Transcriptase Polymerase Chain Reaction, Cell cycle, Gene signature, Flow Cytometry, Molecular biology, High-Throughput Screening Assays, Gene Expression Regulation, Neoplastic, 030104 developmental biology, 030220 oncology & carcinogenesis, Cancer cell, Molecular Medicine, Drug Screening Assays, Antitumor, Biotechnology
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0dbee602aec0943dd6af57df9d435d52
https://pubmed.ncbi.nlm.nih.gov/33482073 -
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المؤلفون: Kallal, Lorena A., Waszkiewicz, Anna, Jon-Paul Jaworski, Pietra, Anthony Della, Berrodin, Tom, Brady, Pat, Jurewicz, Anthony J., Zeng, Xin, Payne, Lisa, Medina, Jesús R., Doepner-Buser, Carolyn, Biju Mangatt
مصطلحات موضوعية: FOS: Clinical medicine, 111599 Pharmacology and Pharmaceutical Sciences not elsewhere classified
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::c1d52f21526c095048c780164829e038
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المؤلفون: Anja Ruusulehto, Andrew J. Plodkowski, Victor D. Martinez, Roger S. Smith, Jason C. Chang, Marc Ladanyi, Maria E. Arcila, Henrik Edgren, Kenneth K.-S. Ng, Gopinath Ganji, Charles M. Rudin, Christopher Matheny, Joshua K. Sabari, Joseph Montecalvo, Huichun Tai, Romel Somwar, Lukas Delasos, Natasha Rekhtman, Alexander Drilon, Ryma Benayed, Gregory J. Riely, Biju Mangatt, Mark G. Kris, Morana Vojnic, William W. Lockwood, Patrice Desmeules
المصدر: Cancer Discovery. 8:686-695
مصطلحات موضوعية: 0301 basic medicine, business.industry, Afatinib, medicine.medical_treatment, Exceptional Responder, Targeted therapy, Clinical trial, 03 medical and health sciences, 030104 developmental biology, 0302 clinical medicine, medicine.anatomical_structure, Oncology, Drug development, Prostate, 030220 oncology & carcinogenesis, mental disorders, Monoclonal, medicine, Cancer research, ERBB3, business, medicine.drug
URL الوصول: https://explore.openaire.eu/search/publication?articleId=doi_________::ba87b5e5e83002dac2bfef7860f03a85
https://doi.org/10.1158/2159-8290.cd-17-1004 -
9دورية أكاديمية
المؤلفون: Biju, Mangatt P., Pyroja, Sulaiman, Rajeshkumar, Neelimmathara V., Paulose, Cheramadathikudyil S.
المصدر: Neurochemical Research. September 2002 27(9):905-910
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10دورية أكاديمية
المؤلفون: Biju, Mangatt P., Pyroja, Sulaiman, Rajeshkumar, Neelimmathara V., Paulose, Cheramadathikudyil S.
المصدر: Molecular and Cellular Biochemistry: An International Journal for Chemical Biology in Health and Disease. January 2001 216(1-2):65-70